| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J W McDonald, F S Silverstein, M V Johnsto. MK-801 pretreatment enhances N-methyl-D-aspartate-mediated brain injury and increases brain N-methyl-D-aspartate recognition site binding in rats. Neuroscience. vol 38. issue 1. 1991-01-24. PMID:2255390. |
a 2 h mk-801 pretreatment produced a 30-50% increase in [3h]glutamate binding at n-methyl-d-aspartate preferring recognition sites in all four brain regions examined (areas ca1 and ca3 of the hippocampus, corpus striatum, cingulate cortex) in comparison with saline-treated controls (p less than 0.05, anova). |
1991-01-24 |
2023-08-11 |
rat |
| H R Olpe, G Karlsso. The effects of baclofen and two GABAB-receptor antagonists on long-term potentiation. Naunyn-Schmiedeberg's archives of pharmacology. vol 342. issue 2. 1990-12-27. PMID:2172841. |
the aim of the present study was to investigate whether activation or inhibition of gabab receptors in hippocampal slices of rats has an impact on the synaptic plasticity in the ca1 area. |
1990-12-27 |
2023-08-11 |
rat |
| M Y Globus, R Busto, E Martinez, I Valdés, W D Dietric. Ischemia induces release of glutamate in regions spared from histopathologic damage in the rat. Stroke. vol 21. issue 11 Suppl. 1990-12-20. PMID:2237984. |
specifically, we compared the temporal profile of ischemia-induced changes in extracellular levels of glutamate in a region selectively vulnerable to 10 minutes of transient ischemia (ca1 sector of the hippocampus) to the changes occurring in regions that, although rendered ischemic, are usually unaffected by a 10-minute insult (i.e., thalamus, cortex, and dorsolateral striatum). |
1990-12-20 |
2023-08-11 |
rat |
| Y Chaput, R C Araneda, R Andrad. Pharmacological and functional analysis of a novel serotonin receptor in the rat hippocampus. European journal of pharmacology. vol 182. issue 3. 1990-12-12. PMID:2226619. |
administration of serotonin (5-hydroxytryptamine, 5-ht) to pyramidal cells of the ca1 region of the hippocampus results in a hyperpolarizing response which is followed by a rebound depolarization and a decrease in the calcium-activated afterhyperpolarization (ahp). |
1990-12-12 |
2023-08-11 |
rat |
| Y Chaput, R C Araneda, R Andrad. Pharmacological and functional analysis of a novel serotonin receptor in the rat hippocampus. European journal of pharmacology. vol 182. issue 3. 1990-12-12. PMID:2226619. |
the present results thus suggest the presence in the ca1 region of the hippocampus of a novel 5-ht receptor at which brl 24924 functions as a selective antagonist and which is capable of mediating slow excitatory responses in central neurons. |
1990-12-12 |
2023-08-11 |
rat |
| U Frey, H Schroeder, H Matthie. Dopaminergic antagonists prevent long-term maintenance of posttetanic LTP in the CA1 region of rat hippocampal slices. Brain research. vol 522. issue 1. 1990-12-10. PMID:1977494. |
dopaminergic antagonists prevent long-term maintenance of posttetanic ltp in the ca1 region of rat hippocampal slices. |
1990-12-10 |
2023-08-11 |
rat |
| U Frey, H Schroeder, H Matthie. Dopaminergic antagonists prevent long-term maintenance of posttetanic LTP in the CA1 region of rat hippocampal slices. Brain research. vol 522. issue 1. 1990-12-10. PMID:1977494. |
the involvement of dopaminergic mechanisms in the induction and maintenance of posttetanic long-term potentiation (ltp) was investigated on ca1 cells of rat hippocampal slices. |
1990-12-10 |
2023-08-11 |
rat |
| K J Sass, D D Spencer, J H Kim, M Westerveld, R A Novelly, T Lenc. Verbal memory impairment correlates with hippocampal pyramidal cell density. Neurology. vol 40. issue 11. 1990-12-10. PMID:2234424. |
after surgical removal of the mesial temporal lobe structures, 2 blinded observers established volumetric cell densities for hippocampal subfields ca1, ca2, ca3, the hilar area, and the granule cell layer of the area dentata. |
1990-12-10 |
2023-08-11 |
Not clear |
| R Trullas, P Skolnic. Functional antagonists at the NMDA receptor complex exhibit antidepressant actions. European journal of pharmacology. vol 185. issue 1. 1990-12-07. PMID:2171955. |
inescapable, but not escapable, stress inhibits the induction of long term potentiation (ltp) in the ca1 region of hippocampus, a process that is dependent upon activation of the n-methyl-d-aspartate (nmda) subtype of glutamate receptor. |
1990-12-07 |
2023-08-11 |
Not clear |
| H Markram, M Sega. Long-lasting facilitation of excitatory postsynaptic potentials in the rat hippocampus by acetylcholine. The Journal of physiology. vol 427. 1990-11-21. PMID:2145426. |
the effects of acetylcholine (ach) on excitatory postsynaptic potentials (epsps) evoked by stimulating schaffer-commissural afferents and on ionophoretically applied l-glutamate ligands, were investigated in ca1 neurones of hippocampal slices using current- and voltage-clamp techniques. |
1990-11-21 |
2023-08-11 |
rat |
| P Ernfors, C Wetmore, L Olson, H Persso. Identification of cells in rat brain and peripheral tissues expressing mRNA for members of the nerve growth factor family. Neuron. vol 5. issue 4. 1990-11-21. PMID:2206535. |
in the rat brain, hdnf mrna was predominantly found in pyramidal neurons in ca1 and ca2 of the hippocampus. |
1990-11-21 |
2023-08-11 |
rat |
| P Andiné, K A Rudolphi, B B Fredholm, H Hagber. Effect of propentofylline (HWA 285) on extracellular purines and excitatory amino acids in CA1 of rat hippocampus during transient ischaemia. British journal of pharmacology. vol 100. issue 4. 1990-11-19. PMID:2207501. |
the influence of propentofylline, on the extracellular concentrations of purines, aspartate and glutamate in the ca1 of the rat hippocampus during transient forebrain ischaemia was investigated. |
1990-11-19 |
2023-08-11 |
rat |
| J T Cummins, M Sack, K von Hunge. The effect of chronic ethanol on glutamate binding in human and rat brain. Life sciences. vol 47. issue 10. 1990-11-15. PMID:2145488. |
a 14% decrease in [3h]-glutamate binding in the hippocampal ca1 region is seen both in the rat after five days of ethanol administration and in postmortem hippocampal tissues from alcoholics. |
1990-11-15 |
2023-08-11 |
human |
| H S Phillips, J M Hains, G R Laramee, A Rosenthal, J W Winslo. Widespread expression of BDNF but not NT3 by target areas of basal forebrain cholinergic neurons. Science (New York, N.Y.). vol 250. issue 4978. 1990-11-14. PMID:1688328. |
within the hippocampus, labeled cells were restricted to ca2, the most medial portion of ca1, and the dentate gyrus. |
1990-11-14 |
2023-08-11 |
human |
| T Kondo, K Ikenaka, H Kato, K Ito, S Aimoto, H Hojo, K Mikoshib. Long-term enhancement of synaptic transmission by synthetic mast cell degranulating peptide and its localization of binding sites in hippocampus. Neuroscience research. vol 8. issue 3. 1990-11-14. PMID:2170876. |
we found that even after brief application of n-biotinyl-mcd (1 microm) to perfusate, its presence was observed in pyramidal cell bodies in the ca1 and ca3 regions, but not in granule cells in the dentate gyrus of the hippocampus slice. |
1990-11-14 |
2023-08-11 |
bee |
| D A Engstrom, M C Bennett, K E Stevens, R L Wilson, D M Diamond, M Fleshner, G M Ros. Modulation of hippocampal primed burst potentiation by anesthesia. Brain research. vol 521. issue 1-2. 1990-11-09. PMID:2207654. |
this study demonstrates that the anesthetics urethane and pentobarbital differentially affect a low threshold form of long-lasting synaptic plasticity, termed primed burst (pb) potentiation, in the ca1 area of rat hippocampus. |
1990-11-09 |
2023-08-11 |
rat |
| C F Kuo, K G Xanthopoulos, J E Darnel. Fetal and adult localization of C/EBP: evidence for combinatorial action of transcription factors in cell-specific gene expression. Development (Cambridge, England). vol 109. issue 2. 1990-10-24. PMID:2401206. |
in the adult brain, it was most concentrated in ca1 to ca4 regions of the hippocampus, in cerebellar purkinje cells, and in layer ii and iii of the cortex. |
1990-10-24 |
2023-08-11 |
mouse |
| M A Whittington, H J Littl. Patterns of changes in field potentials in the isolated hippocampal slice on withdrawal from chronic ethanol treatment of mice in vivo. Brain research. vol 523. issue 2. 1990-10-23. PMID:2400909. |
extracellular recordings were made from isolated hippocampal slices, ca1 area, following withdrawal from chronic ethanol administration to mice of the c57 strain. |
1990-10-23 |
2023-08-11 |
mouse |
| D L Tauck, G A Ashbec. Glycine synergistically potentiates the enhancement of LTP induced by a sulfhydryl reducing agent. Brain research. vol 519. issue 1-2. 1990-10-16. PMID:1975761. |
two selective modulators of n-methyl-d-aspartate (nmda) receptor function, dithiothreitol (dtt) and glycine, each dramatically enhanced long-term potentiation (ltp) in area ca1 of the hippocampus slice. |
1990-10-16 |
2023-08-11 |
Not clear |
| M T Vilaró, J M Palacios, G Mengo. Localization of m5 muscarinic receptor mRNA in rat brain examined by in situ hybridization histochemistry. Neuroscience letters. vol 114. issue 2. 1990-10-11. PMID:2395528. |
the highest hybridization signal was observed in the hippocampus, but restricted to the ventral subiculum, pyramidal cells of the ca1 and, with lower intensity, of the ca2 subfields. |
1990-10-11 |
2023-08-11 |
rat |