| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H E Scharfman, P A Schwartzkroi. Selective depression of GABA-mediated IPSPs by somatostatin in area CA1 of rabbit hippocampal slices. Brain research. vol 493. issue 2. 1989-10-06. PMID:2569913. |
in area ca1 of hippocampus, a subpopulation of gamma-aminobutyric acid (gaba)-containing interneurons that make synaptic contacts on pyramidal cells also contains the neuropeptide, somatostatin. |
1989-10-06 |
2023-08-11 |
rabbit |
| R C Malenka, J A Kauer, D J Perkel, M D Mauk, P T Kelly, R A Nicoll, M N Waxha. An essential role for postsynaptic calmodulin and protein kinase activity in long-term potentiation. Nature. vol 340. issue 6234. 1989-09-25. PMID:2549423. |
in the ca1 region of the hippocampus, the induction of ltp requires activation of nmda (n-methyl-d-aspartate) receptors by synaptically released glutamate with concomitant postsynaptic membrane depolarization. |
1989-09-25 |
2023-08-11 |
Not clear |
| J L Olds, M L Anderson, D L McPhie, L D Staten, D L Alko. Imaging of memory-specific changes in the distribution of protein kinase C in the hippocampus. Science (New York, N.Y.). vol 245. issue 4920. 1989-09-22. PMID:2772638. |
furthermore, classical conditioning of the rabbit nictitating membrane (a form of associative learning) produces translocation of pkc activity from the cytosolic to the membrane compartments of the ca1 region of the hippocampus. |
1989-09-22 |
2023-08-11 |
rabbit |
| K Vass, M L Berger, T S Nowak, W J Welch, H Lassman. Induction of stress protein HSP70 in nerve cells after status epilepticus in the rat. Neuroscience letters. vol 100. issue 1-3. 1989-09-15. PMID:2761775. |
after kainic acid (ka) induced status epilepticus we observed hsp70 immunoreactivity in the hippocampal ca4 and ca1 sectors, the subiculum, the basolateral and the lateral nuclei of the amygdala, the mediodorsal nucleus of the thalamus, the caudal part of the striatum, the claustrum and in neurons of certain neocortical areas. |
1989-09-15 |
2023-08-11 |
rat |
| M P Mattson, S B Kate. Development and selective neurodegeneration in cell cultures from different hippocampal regions. Brain research. vol 490. issue 1. 1989-09-08. PMID:2569350. |
previous studies have shown that pyramidal neurons in hippocampal regions ca1 and ca3 are selectively vulnerable in several neurodegenerative disorders and that a subpopulation of pyramidal neurons in cell cultures of embryonic hippocampus are sensitive to glutamate neurotoxicity. |
1989-09-08 |
2023-08-11 |
rat |
| M P Mattson, S B Kate. Development and selective neurodegeneration in cell cultures from different hippocampal regions. Brain research. vol 490. issue 1. 1989-09-08. PMID:2569350. |
tissue corresponding to the dentate gyrus (dg) and regions ca1, ca2 and ca3 of ammon's horn was removed by microdissection from transverse hippocampal slices and was used to establish cultures of dissociated cells. |
1989-09-08 |
2023-08-11 |
rat |
| R J Sousa, N H Tannery, E M Lafe. In situ hybridization mapping of glucocorticoid receptor messenger ribonucleic acid in rat brain. Molecular endocrinology (Baltimore, Md.). vol 3. issue 3. 1989-08-18. PMID:2747654. |
strong expression of gr mrna was found in the neurons of the ca1 and ca2 fields of the hippocampus and in the paraventricular and periventricular hypothalamic nuclei. |
1989-08-18 |
2023-08-11 |
mouse |
| S G Bec. 5-Carboxyamidotryptamine mimics only the 5-HT elicited hyperpolarization of hippocampal pyramidal cells via 5-HT1A receptor. Neuroscience letters. vol 99. issue 1-2. 1989-08-18. PMID:2748003. |
perfusion of the rat hippocampal slice in vitro by 5-hydroxytryptamine (5-ht) elicits 3 distinct actions recorded intracellularly from pyramidal cells in area ca1: a hyperpolarization, reduction in spike train elicited afterhyperpolarization (ahp) and depolarization. |
1989-08-18 |
2023-08-11 |
rat |
| M L Berger, H Lassmann, O Hornykiewic. Limbic seizures without brain damage after injection of low doses of kainic acid into the amygdala of freely moving rats. Brain research. vol 489. issue 2. 1989-08-11. PMID:2743156. |
after 10 min status epilepticus, we observed marginal neuronal damage with slight gliosis in both hippocampi (ca3 and ca1); after 30 min, hippocampal histopathology was more pronounced, with additional necrosis of the ipsilateral piriform cortex. |
1989-08-11 |
2023-08-11 |
rat |
| H Kojima, M Kowada, Y Katsut. Cellular substrates for epileptiform activity induced by repeated tetanic stimulation in hippocampal slices. Neurologia medico-chirurgica. vol 29. issue 1. 1989-08-10. PMID:2472557. |
using intact and transected hippocampal slices, we investigated the relationship between ca3 and ca1 subfields in the generation of stimulus train-induced bursting. |
1989-08-10 |
2023-08-11 |
Not clear |
| A Represa, C Chanez, M A Flexor, Y Ben-Ar. Development of the cholinergic system in control and intra-uterine growth retarded rat brain. Brain research. Developmental brain research. vol 47. issue 1. 1989-07-28. PMID:2736767. |
the different markers of the cholinergic system were estimated at p (postnatal day) 6, 9, 12, 15, 22 and 60 in cerebellum, hypothalamus, septum, striatum and ca1, ca3 and fascia dentata of the hippocampus. |
1989-07-28 |
2023-08-11 |
rat |
| R M Booze, E A Crisostomo, J N Davi. Species differences in the localization and number of CNS beta adrenergic receptors: rat versus guinea pig. The Journal of pharmacology and experimental therapeutics. vol 249. issue 3. 1989-07-21. PMID:2567353. |
hippocampal area ca1 had high levels of beta-2 adrenergic receptors in both rats and guinea pigs but was accompanied by a widespread distribution of beta-2 adrenergic receptors only in rats. |
1989-07-21 |
2023-08-11 |
rat |
| M Bijak, A Smiałowsk. Functional supersensitivity of the hippocampal dopaminergic system after prolonged treatment with haloperidol. Pharmacology, biochemistry, and behavior. vol 32. issue 1. 1989-07-17. PMID:2567526. |
the effect of acute and prolonged (21 days) treatment with haloperidol (1 or 5 mg/kg sc) on the dopamine-, apomorphine- and ly 171555-induced changes in the firing rate of ca1 layer neurons was studied in a hippocampal slice preparation. |
1989-07-17 |
2023-08-11 |
Not clear |
| H S Swartzwelder, C Ferrari, W W Anderson, W A Wilso. The drug MK-801 attenuates the development, but not the expression, of long-term potentiation and stimulus train-induced bursting in hippocampal slices. Neuropharmacology. vol 28. issue 5. 1989-07-11. PMID:2657480. |
in the present experiment, slices of hippocampus, prepared from rats, were electrically stimulated to produce either long-term potentiation of the ca1 population spike or stimulus train-induced epileptiform bursting in area ca3. |
1989-07-11 |
2023-08-11 |
rat |
| J H Garcia, M L Anderso. Physiopathology of cerebral ischemia. Critical reviews in neurobiology. vol 4. issue 4. 1989-07-10. PMID:2655939. |
several potential culprits have been tried: (1) "energy failure", or depletion of high-energy phosphates, occurs very quickly after ischemia, but energy metabolites recover even in tissues where functional return does not occur; (2) "tissue lactacidosis" enhances ischemic cell necrosis, but this factor is not the indispensable cause of neuronal necrosis because acidosis is minimal or nonexistent under conditions of hypoglycemia and seizures; (3) "impairment of the microcirculation" may be a contributing factor, but such microcirculatory impairment cannot be the initiating event as it is known that irreversible neuronal injury precedes the development of microcirculatory abnormalities; (4) the effects of "excitatory neurotransmitters", especially glutamate, may explain the "delayed neuronal death" or the protracted necrosis of neurons in the ca1 sector of the hippocampus; (5) ionic pump alterations: studies of experimental myocardial ischemia tend to support a contributory role of ca2+ in the aggravation of cell necrosis; however, lack of an experimental model in which steady-state conditions can be maintained has left unresolved the potential participation of calcium ions in ischemic cell necrosis; (6) the same statement, concerning the lack of an experimental model, can be made about the role of free-radical species; oxygen free radicals and superoxides are abundant in the reperfusion stage of ischemic injury, but it is unclear how significant their contribution might be as initiators of ischemic necrosis; and (7) the "ischemic penumbra" is a zone or portion of brain tissue that is sufficiently hypoperfused as to be functionless, but where the cells are likely to recover once normal perfusion is reestablished. |
1989-07-10 |
2023-08-11 |
Not clear |
| P Miu, E Pui. Isoflurane-induced impairment of synaptic transmission in hippocampal neurons. Experimental brain research. vol 75. issue 2. 1989-07-07. PMID:2542074. |
the effects of anaesthetic applications of isoflurane were studied using intracellular recording techniques in 82 ca1 neurons of in vitro hippocampal slice preparations (guinea pigs). |
1989-07-07 |
2023-08-11 |
Not clear |
| H B Michelson, J Kapur, E W Lothma. Reduction of paired pulse inhibition in the CA1 region of the hippocampus by pilocarpine in naive and in amygdala-kindled rats. Experimental neurology. vol 104. issue 3. 1989-07-07. PMID:2721629. |
reduction of paired pulse inhibition in the ca1 region of the hippocampus by pilocarpine in naive and in amygdala-kindled rats. |
1989-07-07 |
2023-08-11 |
rat |
| H B Michelson, J Kapur, E W Lothma. Reduction of paired pulse inhibition in the CA1 region of the hippocampus by pilocarpine in naive and in amygdala-kindled rats. Experimental neurology. vol 104. issue 3. 1989-07-07. PMID:2721629. |
the studies presented here compared the electrophysiologic effects of pilocarpine in vivo in the ca1 region of the hippocampus in naive and amygdala-kindled rats. |
1989-07-07 |
2023-08-11 |
rat |
| F Amenta, C Cavallotti, F Franch, A Ricc. Muscarinic cholinergic receptors in the hippocampus of the aged rat: effects of long-term hydergine administration. Archives internationales de pharmacodynamie et de therapie. vol 297. 1989-06-29. PMID:2730238. |
[3h]-qnb accumulated in the hippocampus of 3 month old rats, primarily in the stratum oriens of the ca1 and ca2 fields, followed in descending order by the molecular layer of granule cells of the dentate gyrus and the ca3 field. |
1989-06-29 |
2023-08-11 |
rat |
| b' Y Hong, K Krnjevi\\xc4\\x8. Serotonin blocks the facilitatory action of muscarinic and nicotinic agents in the hippocampus in vivo. Canadian journal of physiology and pharmacology. vol 67. issue 1. 1989-06-16. PMID:2653594.' |
the inhibitory effect of serotonin, released iontophoretically, on acetylcholine-induced facilitation of population spikes evoked by fimbria-commissural stimulation was studied in the ca1 region of rat hippocampus in vivo. |
1989-06-16 |
2023-08-11 |
rat |