| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nady Braidy, Tarik Smani, Mustafa Nazirogl. Editorial: Involvements of TRP Channels, Oxidative Stress and Apoptosis in Neurodegenerative Diseases. Frontiers in physiology. vol 12. 2021-03-29. PMID:33776800. |
editorial: involvements of trp channels, oxidative stress and apoptosis in neurodegenerative diseases. |
2021-03-29 |
2023-08-13 |
Not clear |
| Panpan Yao, Liping Zhou, Lujie Zhu, Binjie Zhou, Qin Y. Mesenchymal Stem Cells: A Potential Therapeutic Strategy for Neurodegenerative Diseases. European neurology. vol 83. issue 3. 2021-03-18. PMID:32690856. |
neurodegenerative disease is a kind of chronic, progressive nervous system disease characterized by neuron degeneration or apoptosis. |
2021-03-18 |
2023-08-13 |
Not clear |
| Shang-Der Chen, Jenq-Lin Yang, Yi-Chun Lin, A-Ching Chao, Ding-I Yan. Emerging Roles of Inhibitor of Differentiation-1 in Alzheimer's Disease: Cell Cycle Reentry and Beyond. Cells. vol 9. issue 7. 2021-03-05. PMID:32708313. |
a thorough understanding of the underlying mechanisms may provide a rationale to make an earlier intervention before the occurrence of cell cycle reentry and subsequent apoptosis in the fully differentiated neurons during the progression of ad or other neurodegenerative diseases. |
2021-03-05 |
2023-08-13 |
Not clear |
| Junqiang Yan, Hongxia Ma, Xiaoyi Lai, Jiannan Wu, Anran Liu, Jiarui Huang, Wenjie Sun, Mengmeng Shen, Yude Zhan. Artemisinin attenuated oxidative stress and apoptosis by inhibiting autophagy in MPP Journal of biological research (Thessalonike, Greece). vol 28. issue 1. 2021-02-28. PMID:33632304. |
artemisinin attenuated oxidative stress and apoptosis by inhibiting autophagy in mpp parkinson's disease (pd) is the second most common neurodegenerative disease after alzheimer's disease. |
2021-02-28 |
2023-08-13 |
Not clear |
| Dalia M Kopustinskiene, Jurga Bernatonien. Molecular Mechanisms of Melatonin-Mediated Cell Protection and Signaling in Health and Disease. Pharmaceutics. vol 13. issue 2. 2021-02-27. PMID:33498316. |
melatonin protects from oxidative stress in ischemic/reperfusion injury, neurodegenerative diseases, and aging, decreases inflammation, modulates the immune system, inhibits proliferation, counteracts the warburg effect, and promotes apoptosis in various cancer models. |
2021-02-27 |
2023-08-13 |
Not clear |
| Jiayan Li, Xuhui Chen, Xuan Li, Rong Hu, Wenlong Yao, Wei Mei, Li Wan, Lingli Gui, Chuanhan Zhan. Upregulation of Cdh1 in the trigeminal spinal subnucleus caudalis attenuates trigeminal neuropathic pain via inhibiting GABAergic neuronal apoptosis. Neurochemistry international. vol 133. 2021-02-23. PMID:31785347. |
it has also demonstrated that downregulation of the anaphase-promoting complex/cyclosome(apc/c) and its coactivator cdh1 contribute to neuronal apoptosis in diverse neurodegenerative diseases. |
2021-02-23 |
2023-08-13 |
rat |
| Mona Mosayebnia, Maliheh Hajiramezanali, Soraya Shahhossein. Radiolabeled Peptides for Molecular Imaging of Apoptosis. Current medicinal chemistry. vol 27. issue 41. 2021-02-02. PMID:32532184. |
tracking of apoptosis provides an opportunity for the assessment of cardiovascular and neurodegenerative diseases as well as monitoring of cancer therapy at early stages. |
2021-02-02 |
2023-08-13 |
Not clear |
| Lucas A Luna, Zachary Lesecq, Katharine A White, An Hoang, David A Scott, Olga Zagnitko, Andrey A Bobkov, Diane L Barber, Jamie M Schiffer, Daniel G Isom, Christal D Soh. An acidic residue buried in the dimer interface of isocitrate dehydrogenase 1 (IDH1) helps regulate catalysis and pH sensitivity. The Biochemical journal. vol 477. issue 16. 2021-02-01. PMID:32729927. |
this led us to question whether idh1 catalysis is ph-regulated, which would have functional implications under conditions that alter cellular ph, like apoptosis, hypoxia, cancer, and neurodegenerative diseases. |
2021-02-01 |
2023-08-13 |
Not clear |
| Yingfeng Tu, Xiaoling Li, Xuefei Zhu, Xiaokang Liu, Caixia Guo, Da Jia, Tie-Shan Tan. Determining the Fate of Neurons in SCA3: ATX3, a Rising Decision Maker in Response to DNA Stresses and Beyond. Frontiers in cell and developmental biology. vol 8. 2021-01-12. PMID:33425926. |
dna damage response (ddr) and apoptosis are reported to be involved in the pathogenesis of many neurodegenerative diseases including polyglutamine (polyq) disorders, such as spinocerebellar ataxia type 3 (sca3) and huntington's disease (hd). |
2021-01-12 |
2023-08-13 |
Not clear |
| Abu Hazafa, Ammara Batool, Saeed Ahmad, Muhammad Amjad, Sundas Nasir Chaudhry, Jamal Asad, Hasham Feroz Ghuman, Hafiza Madeeha Khan, Muhammad Naeem, Usman Ghan. Humanin: A mitochondrial-derived peptide in the treatment of apoptosis-related diseases. Life sciences. vol 264. 2020-12-31. PMID:33130077. |
based on in vitro and in vivo studies, hn significantly suppressed the apoptosis during the treatment of bone osteoporosis, cardiovascular diseases, diabetes mellitus, and neurodegenerative diseases. |
2020-12-31 |
2023-08-13 |
human |
| Yan-Xia Hao, Mei-Qin Li, Jing-Si Zhang, Qin-Li Zhang, Xia Jiao, Xiu-Liang Ji, Huan Li, Qiao Ni. Aluminum-induced "mixed" cell death in mice cerebral tissue and potential intervention. Neurotoxicity research. vol 37. issue 4. 2020-12-21. PMID:31721047. |
our study evidenced al-induced neuronal necroptosis and apoptosis existing in animal model and suggested potential therapeutic effects of nec-1 and z-vad-fmk on neuronal cell death in neurodegenerative diseases. |
2020-12-21 |
2023-08-13 |
mouse |
| Damilare D Akintade, Bhabatosh Chaudhur. The effect of copy number on α-synuclein's toxicity and its protective role in Bax-induced apoptosis, in yeast. Bioscience reports. vol 40. issue 9. 2020-12-08. PMID:32794578. |
bax and α-synuclein are two human proteins which play a role in the induction of neuronal apoptosis in neurodegenerative diseases like alzheimer's and parkinson's. |
2020-12-08 |
2023-08-13 |
human |
| Yiming Deng, Jingyu Zhang, Xuan Sun, Gaoting Ma, Gang Luo, Zhongrong Miao, Ligang Son. miR-132 improves the cognitive function of rats with Alzheimer's disease by inhibiting the MAPK1 signal pathway. Experimental and therapeutic medicine. vol 20. issue 6. 2020-10-24. PMID:33093897. |
the dysregulation of mirna is crucial in neurodegenerative diseases and neuron apoptosis during ad and is closely associated with the mapk pathway. |
2020-10-24 |
2023-08-13 |
mouse |
| Satoru Tada, Tatsusada Okuno, Mikito Shimizu, Yoshiki Sakai, Hisae Sumi-Akamaru, Makoto Kinoshita, Kazuya Yamashita, Eri Sanda, Chi-Jing Choong, Akiko Namba, Tsutomu Sasaki, Toru Koda, Kazushiro Takata, Shigeru Miyagawa, Yoshiki Sawa, Yuji Nakatsuji, Hideki Mochizuk. Single injection of sustained-release prostacyclin analog ONO-1301-MS ameliorates hypoxic toxicity in the murine model of amyotrophic lateral sclerosis. Scientific reports. vol 9. issue 1. 2020-10-05. PMID:30918303. |
amyotrophic lateral sclerosis (als) is a progressive neurodegenerative disease characterized by several pathologies including oxidative stress, apoptosis, neuroinflammation, and glutamate toxicity. |
2020-10-05 |
2023-08-13 |
mouse |
| Aric Flint Logsdon, Brandon Peter Lucke-Wold, Charles Lee Rosen, Jason Delwyn Hube. Disparity among neural injury models and the unfolded protein response. Journal of neurological disorders & stroke. vol 2. issue 3. 2020-10-01. PMID:27284579. |
evidence suggests that targeting the right transcription factors, at the right time, will aid in the prevention of apoptosis and neurodegenerative disease development following neural injury. |
2020-10-01 |
2023-08-13 |
Not clear |
| Mahsa Eghlidospour, Amir Ghanbari, Seyyed Mohammad Javad Mortazavi, Hassan Azar. Effects of radiofrequency exposure emitted from a GSM mobile phone on proliferation, differentiation, and apoptosis of neural stem cells. Anatomy & cell biology. vol 50. issue 2. 2020-10-01. PMID:28713615. |
due to the importance of neural stem cells (nscs) in plasticity of the nervous system and treating neurodegenerative diseases, the main goal of this study was to evaluate the effects of radiofrequency radiation emitted from a gsm 900-mhz mobile phone with different exposure duration on proliferation, differentiation and apoptosis of adult murine nscs |
2020-10-01 |
2023-08-13 |
Not clear |
| Olena Y Glushakova, Andriy A Glushakov, Dayanjan S Wijesinghe, Alex B Valadka, Ronald L Hayes, Alexander V Glushako. Prospective clinical biomarkers of caspase-mediated apoptosis associated with neuronal and neurovascular damage following stroke and other severe brain injuries: Implications for chronic neurodegeneration. Brain circulation. vol 3. issue 2. 2020-10-01. PMID:30276309. |
apoptosis involving caspase-3 is one of the most common mechanisms involved in the etiopathology of both acute and chronic neurological and neurodegenerative diseases, suggesting a relationship between these disorders. |
2020-10-01 |
2023-08-13 |
Not clear |
| Jens Stepan, Elmira Anderzhanova, Nils C Gasse. Hippo Signaling: Emerging Pathway in Stress-Related Psychiatric Disorders? Frontiers in psychiatry. vol 9. 2020-10-01. PMID:30627107. |
upon diverse extracellular and intracellular stimuli, hippo signaling regulates stemness, cell proliferation and apoptosis by a well-conserved signaling cascade, and disruption of these systems has been implicated in cancer as well as metabolic and neurodegenerative diseases. |
2020-10-01 |
2023-08-13 |
Not clear |
| Md Jakaria, Shofiul Azam, Duk-Yeon Cho, Md Ezazul Haque, In-Su Kim, Dong-Kug Cho. The Methanol Extract of Antioxidants (Basel, Switzerland). vol 8. issue 9. 2020-10-01. PMID:31480531. |
the methanol extract of neuroinflammation, apoptosis, and oxidative stress are connected to the pathogenesis of neurodegenerative diseases (ndds). |
2020-10-01 |
2023-08-13 |
Not clear |
| Mingda Wang, Hongming Sun, Yina Yao, Xicun Tang, Bo W. MicroRNA-217/138-5p downregulation inhibits inflammatory response, oxidative stress and the induction of neuronal apoptosis in MPP American journal of translational research. vol 11. issue 10. 2020-10-01. PMID:31737212. |
microrna-217/138-5p downregulation inhibits inflammatory response, oxidative stress and the induction of neuronal apoptosis in mpp parkinson's disease (pd) is a common neurodegenerative disease. |
2020-10-01 |
2023-08-13 |
Not clear |