Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
N Ramakrishnan, J F Kalinich, D E McClai. Ebselen inhibition of apoptosis by reduction of peroxides. Biochemical pharmacology. vol 51. issue 11. 1996-06-24. PMID:8630085. |
peroxide generation and membrane lipid peroxidation preceded both internucleosomal dna fragmentation and morphological changes characteristic of apoptosis. |
1996-06-24 |
2023-08-12 |
mouse |
N Ramakrishnan, J F Kalinich, D E McClai. Ebselen inhibition of apoptosis by reduction of peroxides. Biochemical pharmacology. vol 51. issue 11. 1996-06-24. PMID:8630085. |
the results suggest that peroxide generation and membrane lipid peroxidation may be important signaling events that trigger apoptosis in irradiated cells. |
1996-06-24 |
2023-08-12 |
mouse |
T Sakamoto, W T Repasky, K Uchida, A Hirata, F Hirat. Modulation of cell death pathways to apoptosis and necrosis of H2O2-treated rat thymocytes by lipocortin I. Biochemical and biophysical research communications. vol 220. issue 3. 1996-05-20. PMID:8607818. |
available evidence suggests that lipocortin i modulates signals for cell death pathways of h2o2-treated rat thymocytes to apoptosis and necrosis by regulating cellular phospholipase a2 activities but not by inhibiting membrane lipid peroxidation. |
1996-05-20 |
2023-08-12 |
rat |
M Peled-Kamar, J Lotem, E Okon, L Sachs, Y Grone. Thymic abnormalities and enhanced apoptosis of thymocytes and bone marrow cells in transgenic mice overexpressing Cu/Zn-superoxide dismutase: implications for Down syndrome. The EMBO journal. vol 14. issue 20. 1995-12-21. PMID:7588627. |
this higher susceptibility to lps-induced apoptosis was associated with an increased production of hydrogen peroxide and a higher degree of lipid peroxidation. |
1995-12-21 |
2023-08-12 |
mouse |
L K Yacoub, F Fogt, B Griniuviene, A A Nanj. Apoptosis and bcl-2 protein expression in experimental alcoholic liver disease in the rat. Alcoholism, clinical and experimental research. vol 19. issue 4. 1995-12-18. PMID:7485830. |
we used the intragastric feeding rat model to investigate the relationship between severity of alcoholic liver injury, apoptosis, bcl-2 protein expression, and lipid peroxidation. |
1995-12-18 |
2023-08-12 |
rat |
P A Sandstrom, D Pardi, P W Tebbey, R W Dudek, D M Terrian, T M Folks, T M Buttk. Lipid hydroperoxide-induced apoptosis: lack of inhibition by Bcl-2 over-expression. FEBS letters. vol 365. issue 1. 1995-07-10. PMID:7774717. |
increased membrane lipid peroxidation has recently been implicated as being associated with apoptosis. |
1995-07-10 |
2023-08-12 |
Not clear |
J M McCor. Superoxide radical: controversies, contradictions, and paradoxes. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). vol 209. issue 2. 1995-07-06. PMID:7770461. |
several examples of the radical's schizophrenic behavior include its roles in bactericidal action versus inflammation, as a modulator of cell division versus malignant transformation and apoptosis, and as both an initiator and a terminator of lipid peroxidation. |
1995-07-06 |
2023-08-12 |
Not clear |
S Haldar, N Jena, C M Croc. Inactivation of Bcl-2 by phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. vol 92. issue 10. 1995-06-16. PMID:7753834. |
in addition, phosphorylated bcl-2 can no longer prevent lipid peroxidation as required to protect cells from apoptosis. |
1995-06-16 |
2023-08-12 |
Not clear |
V S Posokhov, O A Rozenberg, K P Khanso. [Modification of radiation sensitivity of lymphocytes of the rat thymus gland using cholesterol-enriched autoliposomes]. Biulleten' eksperimental'noi biologii i meditsiny. vol 113. issue 2. 1992-07-27. PMID:1611053. |
it was found that in the modified cells the processes of lipid peroxidation, enzymatic degradation of chromatin and apoptosis are inhibited. |
1992-07-27 |
2023-08-11 |
rat |