| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Tenneti, D M D'Emilia, C M Troy, S A Lipto. Role of caspases in N-methyl-D-aspartate-induced apoptosis in cerebrocortical neurons. Journal of neurochemistry. vol 71. issue 3. 1998-09-21. PMID:9721720. |
taken together, our results suggest that ca2+ influx and mitochondrial depolarization occur upstream from caspase activation, whereas ros formation and lipid peroxidation may be downstream events in the cascade leading to cortical neuronal apoptosis. |
1998-09-21 |
2023-08-12 |
Not clear |
| C L Limoli, A Hartmann, L Shephard, C R Yang, D A Boothman, J Bartholomew, W F Morga. Apoptosis, reproductive failure, and oxidative stress in Chinese hamster ovary cells with compromised genomic integrity. Cancer research. vol 58. issue 16. 1998-09-17. PMID:9721883. |
induction of apoptosis by agents such as actinomycin d, etoposide, and staurosporine and induction of necrosis by sodium azide were accompanied by an increase in the level of intracellular peroxy radicals and lipid peroxidation products, two independent end points that are typically associated with oxidative stress. |
1998-09-17 |
2023-08-12 |
Not clear |
| R A Hawkins, K Sangster, M J Arend. Apoptotic death of pancreatic cancer cells induced by polyunsaturated fatty acids varies with double bond number and involves an oxidative mechanism. The Journal of pathology. vol 185. issue 1. 1998-09-15. PMID:9713361. |
the extent of pufa-induced lipid peroxidation, measured as malondialdehyde (mda), also correlated with the proportion of apoptosis induced in mia-pa-ca-2 cells (r = 0.69, p = 0.025) or hl-60 cells (r = 0.64, p = 0.043), as well as with the number of fatty acid double bonds (r = 0.82, p = 0.0015). |
1998-09-15 |
2023-08-12 |
Not clear |
| C Velez-Pardo, M J Del Rio, G Ebinger, G Vauqueli. Monoamine and iron-related toxicity: from "serotonin-binding proteins" to lipid peroxidation and apoptosis in PC12 cells. General pharmacology. vol 31. issue 1. 1998-08-05. PMID:9595272. |
monoamine and iron-related toxicity: from "serotonin-binding proteins" to lipid peroxidation and apoptosis in pc12 cells. |
1998-08-05 |
2023-08-12 |
Not clear |
| C Velez-Pardo, M J Del Rio, G Ebinger, G Vauqueli. Monoamine and iron-related toxicity: from "serotonin-binding proteins" to lipid peroxidation and apoptosis in PC12 cells. General pharmacology. vol 31. issue 1. 1998-08-05. PMID:9595272. |
dopamine in combination with iron induces lipid peroxidation and apoptosis in pc12 cells by a stress oxidative-ca2+ independent mechanism. |
1998-08-05 |
2023-08-12 |
Not clear |
| A A Nanj. Apoptosis and alcoholic liver disease. Seminars in liver disease. vol 18. issue 2. 1998-08-03. PMID:9606815. |
exposure of hep g2 cells expressing cytochrome p450 2e1 to arachidonic acid leads to increased lipid peroxidation and apoptosis. |
1998-08-03 |
2023-08-12 |
Not clear |
| J Frank, D K Kelleher, A Pompella, O Thews, H K Biesalski, P Vaupe. Enhancement of oxidative cell injury and antitumor effects of localized 44 degrees C hyperthermia upon combination with respiratory hyperoxia and xanthine oxidase. Cancer research. vol 58. issue 13. 1998-07-23. PMID:9661874. |
tumors were investigated for: (a) thiobarbituric acid-reactive substance formation and protein-bound 4-hydroxynonenal, as indicators of lipid peroxidation; (b) reactive oxygen-mediated protein modifications; (c) apoptosis; and (d) tumor volume growth. |
1998-07-23 |
2023-08-12 |
rat |
| J Frank, D K Kelleher, A Pompella, O Thews, H K Biesalski, P Vaupe. Enhancement of oxidative cell injury and antitumor effects of localized 44 degrees C hyperthermia upon combination with respiratory hyperoxia and xanthine oxidase. Cancer research. vol 58. issue 13. 1998-07-23. PMID:9661874. |
these findings indicate that the antitumor effect of ht is at least partially mediated through the selective induction of lipid peroxidation and oxidative injury in tumor cells, leading to apoptosis. |
1998-07-23 |
2023-08-12 |
rat |
| I Giardino, A K Fard, D L Hatchell, M Brownle. Aminoguanidine inhibits reactive oxygen species formation, lipid peroxidation, and oxidant-induced apoptosis. Diabetes. vol 47. issue 7. 1998-07-10. PMID:9648836. |
aminoguanidine inhibits reactive oxygen species formation, lipid peroxidation, and oxidant-induced apoptosis. |
1998-07-10 |
2023-08-12 |
rat |
| I Giardino, A K Fard, D L Hatchell, M Brownle. Aminoguanidine inhibits reactive oxygen species formation, lipid peroxidation, and oxidant-induced apoptosis. Diabetes. vol 47. issue 7. 1998-07-10. PMID:9648836. |
in this study, the effects of preincubation with ag on oxidant-induced apoptosis, oxidant-induced intracellular reactive oxygen species (ros) production, and lipid peroxidation were determined in rat retinal müller cells and compared with the effects of ngf, a protein that protects neuronal cells from oxidative stress. |
1998-07-10 |
2023-08-12 |
rat |
| I Giardino, A K Fard, D L Hatchell, M Brownle. Aminoguanidine inhibits reactive oxygen species formation, lipid peroxidation, and oxidant-induced apoptosis. Diabetes. vol 47. issue 7. 1998-07-10. PMID:9648836. |
these data demonstrate that ag can act as an antioxidant in vivo, quenching hydroxyl radicals and lipid peroxidation in cells and tissues and preventing oxidant-induced apoptosis. |
1998-07-10 |
2023-08-12 |
rat |
| Q Chen, A I Cederbau. Cytotoxicity and apoptosis produced by cytochrome P450 2E1 in Hep G2 cells. Molecular pharmacology. vol 53. issue 4. 1998-05-06. PMID:9547353. |
the antioxidants vitamin e, vitamin c, or trolox prevented the lipid peroxidation as well as the cytotoxicity and apoptosis, as did transfection with plasmid containing antisense cyp2e1 or overexpression of bcl-2. |
1998-05-06 |
2023-08-12 |
Not clear |
| Q Chen, A I Cederbau. Cytotoxicity and apoptosis produced by cytochrome P450 2E1 in Hep G2 cells. Molecular pharmacology. vol 53. issue 4. 1998-05-06. PMID:9547353. |
elevated lipid peroxidation plays an important role in the cyp2e1-dependent toxicity and apoptosis. |
1998-05-06 |
2023-08-12 |
Not clear |
| J C Copin, Y Li, L Reola, P H Cha. Trolox and 6,7-dinitroquinoxaline-2,3-dione prevent necrosis but not apoptosis in cultured neurons subjected to oxygen deprivation. Brain research. vol 784. issue 1-2. 1998-04-30. PMID:9518539. |
the results show that 6, 7-dinitroquinoxaline-2,3-dione (dnqx) and 6-hydroxy-2,5,7, 8-tetramethylchroman-2-carboxylic acid (trolox), which interfered with kainate receptor activation and lipid peroxidation respectively, prevented necrosis but allowed neurons to undergo apoptosis. |
1998-04-30 |
2023-08-12 |
Not clear |
| T T Turner, K S Tung, H Tomomasa, L W Wilso. Acute testicular ischemia results in germ cell-specific apoptosis in the rat. Biology of reproduction. vol 57. issue 6. 1998-02-11. PMID:9408230. |
testes were examined for evidence of 1) in situ apoptosis by the terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate (dutp)-biotin nick-end labeling (tunel) technique, 2) apoptosis by the dna "laddering" technique, 3) leukocyte margination and diapedesis in testicular vessels by immunocytochemical and histological techniques, and 4) testicular lipid peroxidation by the thiobarbituric acid reactive substances assay. |
1998-02-11 |
2023-08-12 |
rat |
| J N Keller, M S Kindy, F W Holtsberg, D K St Clair, H C Yen, A Germeyer, S M Steiner, A J Bruce-Keller, J B Hutchins, M P Mattso. Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 2. 1998-02-03. PMID:9425011. |
mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction. |
1998-02-03 |
2023-08-12 |
mouse |
| J N Keller, M S Kindy, F W Holtsberg, D K St Clair, H C Yen, A Germeyer, S M Steiner, A J Bruce-Keller, J B Hutchins, M P Mattso. Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 2. 1998-02-03. PMID:9425011. |
the peroxynitrite scavenger uric acid and the antioxidants propyl gallate and glutathione prevented apoptosis induced by each apoptotic insult, suggesting central roles for peroxynitrite and membrane lipid peroxidation in oxidative stress-induced apoptosis. |
1998-02-03 |
2023-08-12 |
mouse |
| A J Bruce-Keller, J G Begley, W Fu, D A Butterfield, D E Bredesen, J B Hutchins, K Hensley, M P Mattso. Bcl-2 protects isolated plasma and mitochondrial membranes against lipid peroxidation induced by hydrogen peroxide and amyloid beta-peptide. Journal of neurochemistry. vol 70. issue 1. 1998-02-02. PMID:9422344. |
collectively, our data suggest that bcl-2 is localized to mitochondrial and plasma membranes where it can act locally to suppress oxidative damage induced by a beta and h2o2, further highlighting the important role of lipid peroxidation in apoptosis. |
1998-02-02 |
2023-08-12 |
Not clear |
| J M Villalba, F Navarro, C Gómez-Díaz, A Arroyo, R I Bello, P Nava. Role of cytochrome b5 reductase on the antioxidant function of coenzyme Q in the plasma membrane. Molecular aspects of medicine. vol 18 Suppl. 1997-11-14. PMID:9266501. |
addition of coq to intact cells prevents serum withdrawal-induced lipid peroxidation and apoptosis. |
1997-11-14 |
2023-08-12 |
Not clear |
| M P Barroso, C Gómez-Díaz, J M Villalba, M I Burón, G López-Lluch, P Nava. Plasma membrane ubiquinone controls ceramide production and prevents cell death induced by serum withdrawal. Journal of bioenergetics and biomembranes. vol 29. issue 3. 1997-11-14. PMID:9298711. |
hl-60 cells were sensitive to serum removal, and an increase of lipid peroxidation and apoptosis was observed. |
1997-11-14 |
2023-08-12 |
Not clear |