| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R P Bissonnette, A McGahon, A Mahboubi, D R Gree. Functional Myc-Max heterodimer is required for activation-induced apoptosis in T cell hybridomas. The Journal of experimental medicine. vol 180. issue 6. 1994-12-23. PMID:7964516. |
further, coexpression of a reciprocally mutant myc protein capable of forming functional heterodimers with the mutant max can compensate for the dominant negative activity and restore activation-induced apoptosis. |
1994-12-23 |
2023-08-12 |
Not clear |
| R P Bissonnette, A McGahon, A Mahboubi, D R Gree. Functional Myc-Max heterodimer is required for activation-induced apoptosis in T cell hybridomas. The Journal of experimental medicine. vol 180. issue 6. 1994-12-23. PMID:7964516. |
these results imply that myc promotes activation-induced apoptosis by obligatory heterodimerization with max, and therefore, by regulating gene transcription. |
1994-12-23 |
2023-08-12 |
Not clear |
| I Västrik, T P Mäkelä, P J Koskinen, J Klefstrom, K Alital. Myc protein: partners and antagonists. Critical reviews in oncogenesis. vol 5. issue 1. 1994-12-15. PMID:7948108. |
interestingly, it appears that myc not only drives the cell cycle, but also induces cell death by apoptosis in certain situations. |
1994-12-15 |
2023-08-12 |
human |
| S R Hann, M Dixit, R C Sears, L Seal. The alternatively initiated c-Myc proteins differentially regulate transcription through a noncanonical DNA-binding site. Genes & development. vol 8. issue 20. 1994-12-02. PMID:7958908. |
the myc proto-oncogene family has been implicated in multiple cellular processes, including proliferation, differentiation, and apoptosis. |
1994-12-02 |
2023-08-12 |
Not clear |
| J D Mountz, J Wu, J Cheng, T Zho. Autoimmune disease. A problem of defective apoptosis. Arthritis and rheumatism. vol 37. issue 10. 1994-11-14. PMID:7524507. |
oncogenes, including bcl-2, p53, and myc, that regulate apoptosis are also expressed abnormally. |
1994-11-14 |
2023-08-12 |
human |
| C H Chen, J Zhang, C C Lin. Transfected c-myc and c-Ha-ras modulate radiation-induced apoptosis in rat embryo cells. Radiation research. vol 139. issue 3. 1994-09-27. PMID:8073113. |
we studied radiation-induced apoptosis in rat embryo cells (rec) and in rec transfected with a c-myc oncogene [rec:myc(ch1)] or with a c-ha-ras oncogene [rec:ras(ch1)], or both [rec:myc+ras(ch1)]. |
1994-09-27 |
2023-08-12 |
rat |
| C H Chen, J Zhang, C C Lin. Transfected c-myc and c-Ha-ras modulate radiation-induced apoptosis in rat embryo cells. Radiation research. vol 139. issue 3. 1994-09-27. PMID:8073113. |
radiation-induced apoptosis in rec:ras(ch1) was mildly reduced, but that in rec:myc(ch1) and rec:myc+ras(ch1) was significantly increased, relative to that in rec. |
1994-09-27 |
2023-08-12 |
rat |
| C H Chen, J Zhang, C C Lin. Transfected c-myc and c-Ha-ras modulate radiation-induced apoptosis in rat embryo cells. Radiation research. vol 139. issue 3. 1994-09-27. PMID:8073113. |
the percentage of rec:myc(ch1) and rec:myc+ras(ch1) cells undergoing apoptosis increased rapidly at low doses to about 40% at 5 gy irradiation and reached a plateau at high doses (of about 60% at > 15 gy). |
1994-09-27 |
2023-08-12 |
rat |
| M J Arends, A H McGregor, A H Wylli. Apoptosis is inversely related to necrosis and determines net growth in tumors bearing constitutively expressed myc, ras, and HPV oncogenes. The American journal of pathology. vol 144. issue 5. 1994-06-06. PMID:8178928. |
apoptosis is inversely related to necrosis and determines net growth in tumors bearing constitutively expressed myc, ras, and hpv oncogenes. |
1994-06-06 |
2023-08-12 |
mouse |
| W Gu, K Bhatia, I T Magrath, C V Dang, R Dalla-Faver. Binding and suppression of the Myc transcriptional activation domain by p107. Science (New York, N.Y.). vol 264. issue 5156. 1994-05-03. PMID:8146655. |
an amino-terminal transactivation domain is required for myc to function as a transcription factor controlling cell proliferation, differentiation, and apoptosis. |
1994-05-03 |
2023-08-12 |
Not clear |
| M Selvakumaran, H K Lin, R T Sjin, J C Reed, D A Liebermann, B Hoffma. The novel primary response gene MyD118 and the proto-oncogenes myb, myc, and bcl-2 modulate transforming growth factor beta 1-induced apoptosis of myeloid leukemia cells. Molecular and cellular biology. vol 14. issue 4. 1994-04-28. PMID:8139540. |
the novel primary response gene myd118 and the proto-oncogenes myb, myc, and bcl-2 modulate transforming growth factor beta 1-induced apoptosis of myeloid leukemia cells. |
1994-04-28 |
2023-08-12 |
Not clear |
| G Fischer, S C Kent, L Joseph, D R Green, D W Scot. Lymphoma models for B cell activation and tolerance. X. Anti-mu-mediated growth arrest and apoptosis of murine B cell lymphomas is prevented by the stabilization of myc. The Journal of experimental medicine. vol 179. issue 1. 1994-02-02. PMID:8270867. |
x. anti-mu-mediated growth arrest and apoptosis of murine b cell lymphomas is prevented by the stabilization of myc. |
1994-02-02 |
2023-08-12 |
Not clear |
| G Fischer, S C Kent, L Joseph, D R Green, D W Scot. Lymphoma models for B cell activation and tolerance. X. Anti-mu-mediated growth arrest and apoptosis of murine B cell lymphomas is prevented by the stabilization of myc. The Journal of experimental medicine. vol 179. issue 1. 1994-02-02. PMID:8270867. |
northern and western analyses show that c-myc message and the levels of multiple myc proteins were maintained in the presence of antisense c-myc, results indicating that myc species are critical for the continuation of proliferation and the prevention of apoptosis. |
1994-02-02 |
2023-08-12 |
Not clear |
| B Amati, T D Littlewood, G I Evan, H Lan. The c-Myc protein induces cell cycle progression and apoptosis through dimerization with Max. The EMBO journal. vol 12. issue 13. 1994-01-26. PMID:8262051. |
the c-myc protein (myc) is involved in cellular transformation and mitogenesis, but is also a potent inducer of programmed cell death, or apoptosis. |
1994-01-26 |
2023-08-12 |
Not clear |
| A E Milner, R J Grand, C M Waters, C D Gregor. Apoptosis in Burkitt lymphoma cells is driven by c-myc. Oncogene. vol 8. issue 12. 1993-12-29. PMID:8247541. |
here we show that ifn-alpha-mediated suppression of apoptosis in group i bl cells corresponds temporally with inhibition of myc protein levels. |
1993-12-29 |
2023-08-12 |
Not clear |
| Y Wang, L Szekely, I Okan, G Klein, K G Wima. Wild-type p53-triggered apoptosis is inhibited by bcl-2 in a v-myc-induced T-cell lymphoma line. Oncogene. vol 8. issue 12. 1993-12-29. PMID:8247547. |
we have suggested that apoptosis is elicited by the contradictory signals emanating from the constitutively activated myc gene and the growth arresting signal of wt p53 (ramqvist et al., 1993; wang et al., 1993). |
1993-12-29 |
2023-08-12 |
Not clear |
| Y Wang, L Szekely, I Okan, G Klein, K G Wima. Wild-type p53-triggered apoptosis is inhibited by bcl-2 in a v-myc-induced T-cell lymphoma line. Oncogene. vol 8. issue 12. 1993-12-29. PMID:8247547. |
these results suggest that bcl-2 may prevent apoptosis in cells simultaneously exposed to the proliferation-stimulating effect of activated myc and the growth arresting signal of wt p53. |
1993-12-29 |
2023-08-12 |
Not clear |
| D S Askew, J N Ihle, J L Clevelan. Activation of apoptosis associated with enforced myc expression in myeloid progenitor cells is dominant to the suppression of apoptosis by interleukin-3 or erythropoietin. Blood. vol 82. issue 7. 1993-11-10. PMID:8400257. |
activation of apoptosis associated with enforced myc expression in myeloid progenitor cells is dominant to the suppression of apoptosis by interleukin-3 or erythropoietin. |
1993-11-10 |
2023-08-12 |
Not clear |
| D S Askew, J N Ihle, J L Clevelan. Activation of apoptosis associated with enforced myc expression in myeloid progenitor cells is dominant to the suppression of apoptosis by interleukin-3 or erythropoietin. Blood. vol 82. issue 7. 1993-11-10. PMID:8400257. |
the studies described here examine the ability of interleukin-3 (il-3) or erythropoietin (epo) to suppress apoptosis that occurs in association with enforced myc expression during cell cycle arrest of a murine il-3-dependent myeloid progenitor cell line, 32d. |
1993-11-10 |
2023-08-12 |
Not clear |
| A J Wagner, M B Small, N Ha. Myc-mediated apoptosis is blocked by ectopic expression of Bcl-2. Molecular and cellular biology. vol 13. issue 4. 1993-04-20. PMID:8455620. |
these results imply that apoptosis serves as a protective mechanism to prevent tumorigenicity elicited by deregulated myc expression. |
1993-04-20 |
2023-08-12 |
rat |