| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Guo, C Chen, C Vidair, S Marino, W C Dewey, C C Lin. Characterization of radiation-induced apoptosis in rodent cell lines. Radiation research. vol 147. issue 3. 1997-03-26. PMID:9052675. |
comparing the dose response for apoptosis and the clonogenic survival curves for rat1 and rat1:myc(b) cells, we concluded that radiation-induced apoptosis contributed to the overall radiation-induced cell inactivation as assayed by clonogenic survival, and that a modified linear-quadratic model, proposed previously, modeled such a contribution effectively. |
1997-03-26 |
2023-08-12 |
Not clear |
| G Cutrona, M Dono, S Pastorino, M Ulivi, V L Burgio, S Zupo, S Roncella, M Ferrarin. The propensity to apoptosis of centrocytes and centroblasts correlates with elevated levels of intracellular myc protein. European journal of immunology. vol 27. issue 1. 1997-03-05. PMID:9022024. |
the propensity to apoptosis of centrocytes and centroblasts correlates with elevated levels of intracellular myc protein. |
1997-03-05 |
2023-08-12 |
Not clear |
| G Cutrona, M Dono, S Pastorino, M Ulivi, V L Burgio, S Zupo, S Roncella, M Ferrarin. The propensity to apoptosis of centrocytes and centroblasts correlates with elevated levels of intracellular myc protein. European journal of immunology. vol 27. issue 1. 1997-03-05. PMID:9022024. |
separation of gc b cells into centroblasts and centrocytes revealed that, while differing in their cell cycle status, surface marker expression and morphology, the two cell types had the same propensity to apoptosis and elevated myc protein expression, thus reinforcing the notion of a close correlation between these two events. |
1997-03-05 |
2023-08-12 |
Not clear |
| G Cutrona, M Dono, S Pastorino, M Ulivi, V L Burgio, S Zupo, S Roncella, M Ferrarin. The propensity to apoptosis of centrocytes and centroblasts correlates with elevated levels of intracellular myc protein. European journal of immunology. vol 27. issue 1. 1997-03-05. PMID:9022024. |
based upon these observations and other considerations it is proposed that elevation of myc proteins confers to gc b cells a particular propensity to apoptosis, while the subsequent decision between progression into the cell cycle or programmed cell death is dictated by other signals that are delivered in the gc and perhaps operate at the level of other proto-oncogenes. |
1997-03-05 |
2023-08-12 |
Not clear |
| M Zörnig, G I Eva. Cell cycle: on target with Myc. Current biology : CB. vol 6. issue 12. 1997-02-27. PMID:8994810. |
the cdc25a protein phosphatase is required both for progression through mitosis and for myc-induced apoptosis, making cdc25a the most attractive myc target gene identified so far. |
1997-02-27 |
2023-08-12 |
Not clear |
| L Desbarats, A Schneider, D Müller, A Bürgin, M Eiler. Myc: a single gene controls both proliferation and apoptosis in mammalian cells. Experientia. vol 52. issue 12. 1997-01-29. PMID:8988255. |
myc: a single gene controls both proliferation and apoptosis in mammalian cells. |
1997-01-29 |
2023-08-12 |
Not clear |
| L Desbarats, A Schneider, D Müller, A Bürgin, M Eiler. Myc: a single gene controls both proliferation and apoptosis in mammalian cells. Experientia. vol 52. issue 12. 1997-01-29. PMID:8988255. |
myc also induces cells to undergo apoptosis, unless specific signals provided either by cytokines or by oncogenes block the apoptotic pathway. |
1997-01-29 |
2023-08-12 |
Not clear |
| P Gallant, Y Shiio, P F Cheng, S M Parkhurst, R N Eisenma. Myc and Max homologs in Drosophila. Science (New York, N.Y.). vol 274. issue 5292. 1996-12-26. PMID:8929412. |
the proteins encoded by the myc proto-oncogene family are involved in cell proliferation, apoptosis, differentiation, and neoplasia. |
1996-12-26 |
2023-08-12 |
drosophila_melanogaster |
| V A Polunovsky, I B Rosenwald, A T Tan, J White, L Chiang, N Sonenberg, P B Bitterma. Translational control of programmed cell death: eukaryotic translation initiation factor 4E blocks apoptosis in growth-factor-restricted fibroblasts with physiologically expressed or deregulated Myc. Molecular and cellular biology. vol 16. issue 11. 1996-12-16. PMID:8887686. |
translational control of programmed cell death: eukaryotic translation initiation factor 4e blocks apoptosis in growth-factor-restricted fibroblasts with physiologically expressed or deregulated myc. |
1996-12-16 |
2023-08-12 |
Not clear |
| V A Polunovsky, I B Rosenwald, A T Tan, J White, L Chiang, N Sonenberg, P B Bitterma. Translational control of programmed cell death: eukaryotic translation initiation factor 4E blocks apoptosis in growth-factor-restricted fibroblasts with physiologically expressed or deregulated Myc. Molecular and cellular biology. vol 16. issue 11. 1996-12-16. PMID:8887686. |
increased expression of eif4e was sufficient to inhibit apoptosis in serum-restricted primary fibroblasts with enforced expression of myc. |
1996-12-16 |
2023-08-12 |
Not clear |
| A Borrè, C M Cultraro, S Sega. c-Myc inactivation by mutant Max alters growth and morphology of NCI-H-630 colon cancer cells. Journal of cellular physiology. vol 169. issue 1. 1996-12-13. PMID:8841436. |
the myc gene family has been implicated in multiple cell processes including proliferation, differentiation, tumorigenesis, and apoptosis. |
1996-12-13 |
2023-08-12 |
human |
| S Kagaya, C Kitanaka, Y Kuchin. [Apoptosis induced by myc family genes]. Nihon rinsho. Japanese journal of clinical medicine. vol 54. issue 7. 1996-11-26. PMID:8741680. |
[apoptosis induced by myc family genes]. |
1996-11-26 |
2023-08-12 |
Not clear |
| S Kagaya, C Kitanaka, Y Kuchin. [Apoptosis induced by myc family genes]. Nihon rinsho. Japanese journal of clinical medicine. vol 54. issue 7. 1996-11-26. PMID:8741680. |
however, the intronless myc family genes such as s-myc, n-myc2, mycl2 lack transforming ability and retain only apoptosis inducing activity. |
1996-11-26 |
2023-08-12 |
Not clear |
| S Kagaya, C Kitanaka, Y Kuchin. [Apoptosis induced by myc family genes]. Nihon rinsho. Japanese journal of clinical medicine. vol 54. issue 7. 1996-11-26. PMID:8741680. |
although much remains to be clear regarding the molecular mechanism of apoptosis induction by myc gene expression, our recent results suggest that the intronless myc genes significantly differ from that of the c-myc gene in their requirement for wild-type p53 activity in apoptosis induction. |
1996-11-26 |
2023-08-12 |
Not clear |
| W X Li, C H Chen, C C Ling, G C L. Apoptosis in heat-induced cell killing: the protective role of hsp-70 and the sensitization effect of the c-myc gene. Radiation research. vol 145. issue 3. 1996-11-14. PMID:8927700. |
we studied heat-induced apoptosis and loss of clonogenicity in rat-1 fibroblasts, thermotolerant rat-1 (tt rat-1), rat-1 transfected with the human hsp-70 gene (m21) and rat-1 transfected with the human c-myc proto-oncogene (rat-1:myc). |
1996-11-14 |
2023-08-12 |
human |
| W X Li, C H Chen, C C Ling, G C L. Apoptosis in heat-induced cell killing: the protective role of hsp-70 and the sensitization effect of the c-myc gene. Radiation research. vol 145. issue 3. 1996-11-14. PMID:8927700. |
relative to rat-1, tt rat-1 and m21 cells are heat-resistant, but rat-1:myc cells are heat-sensitive, in terms of both apoptosis and clonogenic survival. |
1996-11-14 |
2023-08-12 |
human |
| A E Borovitskaya, V I Evtushenko, S L Sabo. Gamma-radiation-induced cell death in the fetal rat brain possesses molecular characteristics of apoptosis and is associated with specific messenger RNA elevations. Brain research. Molecular brain research. vol 35. issue 1-2. 1996-10-11. PMID:8717336. |
in contrast, irradiation reduced by 50-70% the abundances of most other mrnas tested, including those for housekeeping proteins, p53, jun, myc, interleukin-1-beta-converting enzyme, and the negative apoptosis regulators bcl-2 and bcl-xl. |
1996-10-11 |
2023-08-12 |
rat |
| K Galaktionov, X Chen, D Beac. Cdc25 cell-cycle phosphatase as a target of c-myc. Nature. vol 382. issue 6591. 1996-09-03. PMID:8700224. |
like myc, cdc25a, itself a proto-oncogene, can induce apoptosis in cells depleted of growth factor, and myc-induced apoptosis also requires cdc25a. |
1996-09-03 |
2023-08-12 |
Not clear |
| B Rudolph, R Saffrich, J Zwicker, B Henglein, R Müller, W Ansorge, M Eiler. Activation of cyclin-dependent kinases by Myc mediates induction of cyclin A, but not apoptosis. The EMBO journal. vol 15. issue 12. 1996-08-27. PMID:8670807. |
activation of cyclin-dependent kinases by myc mediates induction of cyclin a, but not apoptosis. |
1996-08-27 |
2023-08-12 |
Not clear |
| B Rudolph, R Saffrich, J Zwicker, B Henglein, R Müller, W Ansorge, M Eiler. Activation of cyclin-dependent kinases by Myc mediates induction of cyclin A, but not apoptosis. The EMBO journal. vol 15. issue 12. 1996-08-27. PMID:8670807. |
the activation of conditional alleles of myc induces both cell proliferation and apoptosis in serum-deprived rat1 fibroblasts. |
1996-08-27 |
2023-08-12 |
Not clear |