| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| An Wang, Youbo Wang, Qinyun Ma, Xiaofeng Che. The carcinogenesis of esophageal squamous cell cancer is positively regulated by USP13 through WISP1 deubiquitination. BioFactors (Oxford, England). 2024-10-29. PMID:39468941. |
mass spectrometry, immunoprecipitation, and in vitro functional assays were conducted to explore the interaction between usp13 and wisp1 and to assess the effects of usp13 downregulation on cell proliferation, migration, invasion, epithelial-mesenchymal transition (emt), and apoptosis. |
2024-10-29 |
2024-10-31 |
mouse |
| An Wang, Youbo Wang, Qinyun Ma, Xiaofeng Che. The carcinogenesis of esophageal squamous cell cancer is positively regulated by USP13 through WISP1 deubiquitination. BioFactors (Oxford, England). 2024-10-29. PMID:39468941. |
downregulation of usp13 resulted in reduced wisp1 protein stability, decreased cell proliferation, migration, and emt, and increased apoptosis in vitro. |
2024-10-29 |
2024-10-31 |
mouse |
| Dian Liu, Mingjun Zhang, Jingjing Tian, Mingxiao Gao, Ming Liu, Xiangrui Fu, Tao Jin, Jinyu Pan, Fangna Chen, Fengshuang A. WNT1-inducible signalling pathway protein 1 stabilizes atherosclerotic plaques in apolipoprotein-E-deficient mice via the focal adhesion kinase/mitogen-activated extracellular signal-regulated kinase/extracellular signal-regulated kinase pathway. Journal of hypertension. 2022-07-26. PMID:35881419. |
the relationship between wisp1 and apoptosis of vsmcs has not been determined previously. |
2022-07-26 |
2023-08-14 |
mouse |
| Sensen Lv, Xiaolu Qu, Yan Qu, Yun Wan. LncRNA NEAT1 Knockdown Alleviates Lipopolysaccharide-Induced Acute Lung Injury by Modulation of miR-182-5p/WISP1 Axis. Biochemical genetics. vol 59. issue 6. 2021-10-28. PMID:34046810. |
moreover, neat1 knockdown could accelerate cell viability and inhibit cell apoptosis and inflammation in lps-induced mh-s cells by elevating mir-182-5p and decreasing wisp1 in lps-exposed mh-s cells. |
2021-10-28 |
2023-08-13 |
mouse |
| Shujun Chen, Bo L. MiR-128-3p Post-Transcriptionally Inhibits WISP1 to Suppress Apoptosis and Inflammation in Human Articular Chondrocytes via the PI3K/AKT/NF-κB Signaling Pathway. Cell transplantation. vol 29. 2021-07-09. PMID:32830547. |
the effect of mir-128-3p or wisp1 on chondrocytes was evaluated by cell proliferation assay, apoptosis, and caspase-3 activity assay. |
2021-07-09 |
2023-08-13 |
human |
| Shujun Chen, Bo L. MiR-128-3p Post-Transcriptionally Inhibits WISP1 to Suppress Apoptosis and Inflammation in Human Articular Chondrocytes via the PI3K/AKT/NF-κB Signaling Pathway. Cell transplantation. vol 29. 2021-07-09. PMID:32830547. |
our results showed that mir-128-3p targets wisp1 to regulate chondrocyte proliferation, apoptosis, degradation of chondrocyte matrix, and production of proinflammatory cytokines via the pi3k/akt/nf-κb pathway, which plays a suppressed role in oa. |
2021-07-09 |
2023-08-13 |
human |
| Shujun Chen, Bo L. MiR-128-3p Post-Transcriptionally Inhibits WISP1 to Suppress Apoptosis and Inflammation in Human Articular Chondrocytes via the PI3K/AKT/NF-κB Signaling Pathway. Cell transplantation. vol 29. 2021-07-09. PMID:32830547. |
mir-128-3p post-transcriptionally inhibits wisp1 to suppress apoptosis and inflammation in human articular chondrocytes via the pi3k/akt/nf-κb signaling pathway. |
2021-07-09 |
2023-08-13 |
human |
| Shujun Chen, Bo L. MiR-128-3p Post-Transcriptionally Inhibits WISP1 to Suppress Apoptosis and Inflammation in Human Articular Chondrocytes via the PI3K/AKT/NF-κB Signaling Pathway. Cell transplantation. vol 29. 2021-07-09. PMID:32830547. |
overexpression of wisp1 inhibited the proliferation of chondrocytes, which induced apoptosis, degradation of chondrocyte matrix, production of proinflammatory cytokines, and activated the phosphatidylinositol-3-kinase (pi3k)/protein kinase b (akt)/nuclear factor kappa-light-chain-enhancer of activated b cells (nf-κb) pathway. |
2021-07-09 |
2023-08-13 |
human |
| Chao Cheng, Jian Tian, Fangjie Zhang, Zhenhan Deng, Min Tu, Liangjun Li, Hua Yang, Kai Xiao, Wei Guo, Ruiqi Yang, Shuguang Gao, Zhihong Zho. WISP1 Protects Against Chondrocyte Senescence and Apoptosis by Regulating αvβ3 and PI3K/Akt Pathway in Osteoarthritis. DNA and cell biology. vol 40. issue 4. 2021-04-13. PMID:33646053. |
wisp1 protects against chondrocyte senescence and apoptosis by regulating αvβ3 and pi3k/akt pathway in osteoarthritis. |
2021-04-13 |
2023-08-13 |
human |
| Feng Wei, Sang Ba, Mei Jin, Ren Ci, Xuelian Wang, Fusheng E, Ziwen Lon. RNF180 Inhibits Proliferation and Promotes Apoptosis of Colorectal Cancer Through Ubiquitination of WISP1. Frontiers in cell and developmental biology. vol 8. 2021-02-10. PMID:33553163. |
rnf180 inhibits proliferation and promotes apoptosis of colorectal cancer through ubiquitination of wisp1. |
2021-02-10 |
2023-08-13 |
mouse |
| Yanyan Zhu, Wei Li, Yuanyuan Yang, You Li, Yueyue Zha. WISP1 indicates poor prognosis and regulates cell proliferation and apoptosis in gastric cancer via targeting AKT/mTOR signaling pathway. American journal of translational research. vol 12. issue 11. 2020-12-16. PMID:33312368. |
wisp1 indicates poor prognosis and regulates cell proliferation and apoptosis in gastric cancer via targeting akt/mtor signaling pathway. |
2020-12-16 |
2023-08-13 |
human |
| Yongqi Ye, Pengju Zhang, Yuhang Qian, Baoxin Yin, Meijuan Ya. The Effect of Pyrroloquinoline Quinone on the Expression of WISP1 in Traumatic Brain Injury. Stem cells international. vol 2017. 2020-10-01. PMID:28883836. |
wisp1, as a member of the ccn4 protein family, has cell protective effects of promoting cell proliferation and inhibiting cell apoptosis. |
2020-10-01 |
2023-08-13 |
Not clear |
| Liang Wang, Jin Sun, Hua Ca. MicroRNA-384 regulates cell proliferation and apoptosis through directly targeting WISP1 in laryngeal cancer. Journal of cellular biochemistry. vol 120. issue 3. 2020-06-22. PMID:30548664. |
microrna-384 regulates cell proliferation and apoptosis through directly targeting wisp1 in laryngeal cancer. |
2020-06-22 |
2023-08-13 |
human |
| Liang Wang, Jin Sun, Hua Ca. MicroRNA-384 regulates cell proliferation and apoptosis through directly targeting WISP1 in laryngeal cancer. Journal of cellular biochemistry. vol 120. issue 3. 2020-06-22. PMID:30548664. |
taken together, these data indicate that mir-384 regulates lc cell proliferation and apoptosis through targeting wisp1 signaling pathway, providing a novel insight into the lc treatment. |
2020-06-22 |
2023-08-13 |
human |
| Liang Wang, Jin Sun, Hua Ca. MicroRNA-384 regulates cell proliferation and apoptosis through directly targeting WISP1 in laryngeal cancer. Journal of cellular biochemistry. vol 120. issue 3. 2020-06-22. PMID:30548664. |
wisp1 knockdown by small interfering rna inhibited lc cell proliferation and promoted cell apoptosis. |
2020-06-22 |
2023-08-13 |
human |
| Di Jing, Qian Zhang, Haiming Yu, Yajie Zhao, Liangfang She. Identification of WISP1 as a novel oncogene in glioblastoma. International journal of oncology. vol 51. issue 4. 2018-05-14. PMID:28902353. |
additionally, inhibition of wisp1 greatly suppressed cell proliferation, migration, and invasion and promoted apoptosis and cell cycle arrest of glioblastoma cells. |
2018-05-14 |
2023-08-13 |
Not clear |
| Jianghong Wu, Ziwen Long, Hong Cai, Chunyan Du, Xiaowen Liu, Shengjia Yu, Yanong Wan. High expression of WISP1 in colon cancer is associated with apoptosis, invasion and poor prognosis. Oncotarget. vol 7. issue 31. 2018-02-23. PMID:27409174. |
high expression of wisp1 in colon cancer is associated with apoptosis, invasion and poor prognosis. |
2018-02-23 |
2023-08-13 |
mouse |
| Jianghong Wu, Ziwen Long, Hong Cai, Chunyan Du, Xiaowen Liu, Shengjia Yu, Yanong Wan. High expression of WISP1 in colon cancer is associated with apoptosis, invasion and poor prognosis. Oncotarget. vol 7. issue 31. 2018-02-23. PMID:27409174. |
downregulation of wisp1 inhibited cell proliferation and invasion through increasing apoptosis and blocking cell cycle at g1 phase in cc lovo and rko cells. |
2018-02-23 |
2023-08-13 |
mouse |
| Xiaomin Zhang, Xi Chen, Juan Liu, Xiushuai Dong, Yinglan Jin, Yaoyao Tian, Yanming Xue, Liyan Chen, Yuying Chang, Yao Liu, Jinghua Wan. Knockdown of WISP1 inhibit proliferation and induce apoptosis in ALL Jurkat cells. International journal of clinical and experimental pathology. vol 8. issue 11. 2016-10-24. PMID:26823919. |
furthermore, knockdown of wisp1 induced apoptosis of jurkat cells was also associated with loss of mmp and generation of ros. |
2016-10-24 |
2023-08-13 |
Not clear |
| Xiaomin Zhang, Xi Chen, Juan Liu, Xiushuai Dong, Yinglan Jin, Yaoyao Tian, Yanming Xue, Liyan Chen, Yuying Chang, Yao Liu, Jinghua Wan. Knockdown of WISP1 inhibit proliferation and induce apoptosis in ALL Jurkat cells. International journal of clinical and experimental pathology. vol 8. issue 11. 2016-10-24. PMID:26823919. |
in conclusion, wisp1 plays an important role in proliferation and apoptosis of jurkat cells in mitochondria dependent pathway, the specific mechanisms need further study. |
2016-10-24 |
2023-08-13 |
Not clear |