| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiaomin Zhang, Xi Chen, Juan Liu, Xiushuai Dong, Yinglan Jin, Yaoyao Tian, Yanming Xue, Liyan Chen, Yuying Chang, Yao Liu, Jinghua Wan. Knockdown of WISP1 inhibit proliferation and induce apoptosis in ALL Jurkat cells. International journal of clinical and experimental pathology. vol 8. issue 11. 2016-10-24. PMID:26823919. |
knockdown of wisp1 inhibit proliferation and induce apoptosis in all jurkat cells. |
2016-10-24 |
2023-08-13 |
Not clear |
| Kenneth Maies. New Insights for Oxidative Stress and Diabetes Mellitus. Oxidative medicine and cellular longevity. vol 2015. 2016-03-29. PMID:26064426. |
the mechanistic target of rapamycin (mtor), silent mating type information regulation 2 homolog 1 (s. cerevisiae) (sirt1), and wnt1 inducible signaling pathway protein 1 (wisp1) are especially justified to be considered treatment targets for dm since these pathways can address the complex relationship between stem cells, trophic factors, impaired glucose tolerance, programmed cell death pathways of apoptosis and autophagy, tissue remodeling, cellular energy homeostasis, and vascular biology that greatly impact the biology and disease progression of dm. |
2016-03-29 |
2023-08-13 |
Not clear |
| Sanjukta Chakrabarti, Shaleen Multani, Jyoti Dabholkar, Dhananjaya Saranat. Whole genome expression profiling in chewing-tobacco-associated oral cancers: a pilot study. Medical oncology (Northwood, London, England). vol 32. issue 3. 2016-03-17. PMID:25663065. |
the biological functions and representative deregulated genes include cell proliferation (aim2, fap, tnfsf13b, tmprss11a); signal transduction (folr2, mme, htr3b); invasion and metastasis (spp1, tnfaip6, ephb6); differentiation (clec4a, elf5); angiogenesis (cxcl1); apoptosis (glipr1, wisp1, dapl1); and immune responses (cd300a, ifit2, trem2); and metabolism (nnmt; aldh3a1). |
2016-03-17 |
2023-08-13 |
human |
| Kenneth Maies. Programming apoptosis and autophagy with novel approaches for diabetes mellitus. Current neurovascular research. vol 12. issue 2. 2015-12-29. PMID:25742566. |
multiple treatment approaches are being entertained for dm with wnt1 inducible signaling pathway protein 1 (wisp1), mechanistic target of rapamycin (mtor), and silent mating type information regulation 2 homolog) 1 (s. cerevisiae) (sirt1) generating significant interest as target pathways that can address maintenance of glucose homeostasis as well as prevention of cellular pathology by controlling insulin resistance, stem cell proliferation, and the programmed cell death pathways of apoptosis and autophagy. |
2015-12-29 |
2023-08-13 |
Not clear |
| Kenneth Maies. Stem cell guidance through the mechanistic target of rapamycin. World journal of stem cells. vol 7. issue 7. 2015-09-02. PMID:26328016. |
mtor can control the programmed cell death pathways of autophagy and apoptosis that can yield variable outcomes in stem cell survival and be reliant upon proliferative pathways that include wnt signaling, wnt1 inducible signaling pathway protein 1 (wisp1), silent mating type information regulation 2 homolog 1 (saccharomyces cerevisiae) (sirt1), and trophic factors. |
2015-09-02 |
2023-08-13 |
Not clear |
| Kenneth Maies. WISP1: Clinical insights for a proliferative and restorative member of the CCN family. Current neurovascular research. vol 11. issue 4. 2015-07-01. PMID:25219658. |
wisp1, a target of the wingless pathway wnt1, oversees cellular mechanisms that include apoptosis, autophagy, cellular migration, stem cell proliferation, angiogenesis, immune cell modulation, and tumorigenesis. |
2015-07-01 |
2023-08-13 |
Not clear |
| Katrin Schlegelmilch, Alexander Keller, Viola Zehe, Sylvia Hondke, Tatjana Schilling, Franz Jakob, Ludger Klein-Hitpass, Norbert Schütz. WISP 1 is an important survival factor in human mesenchymal stromal cells. Gene. vol 551. issue 2. 2014-12-09. PMID:25200494. |
accordingly, wisp1 deficiency is likely to cause trail-induced apoptosis. |
2014-12-09 |
2023-08-13 |
human |
| Katrin Schlegelmilch, Alexander Keller, Viola Zehe, Sylvia Hondke, Tatjana Schilling, Franz Jakob, Ludger Klein-Hitpass, Norbert Schütz. WISP 1 is an important survival factor in human mesenchymal stromal cells. Gene. vol 551. issue 2. 2014-12-09. PMID:25200494. |
whereas a dysregulated, excessive expression of wisp1 often reflects its oncogenic potential via the inhibition of apoptosis, our study emphasizes the importance of wisp1 signaling for the survival of primary human cells. |
2014-12-09 |
2023-08-13 |
human |
| Katrin Schlegelmilch, Alexander Keller, Viola Zehe, Sylvia Hondke, Tatjana Schilling, Franz Jakob, Ludger Klein-Hitpass, Norbert Schütz. WISP 1 is an important survival factor in human mesenchymal stromal cells. Gene. vol 551. issue 2. 2014-12-09. PMID:25200494. |
dna microarray analyses of wisp1 down-regulated versus control samples revealed several clusters of differentially expressed genes important for apoptosis induction such as tnf-related apoptosis-inducing ligand 1 (trail) and the corresponding apoptosis-inducing receptors trail-r1 and -r2. |
2014-12-09 |
2023-08-13 |
human |
| Katrin Schlegelmilch, Alexander Keller, Viola Zehe, Sylvia Hondke, Tatjana Schilling, Franz Jakob, Ludger Klein-Hitpass, Norbert Schütz. WISP 1 is an important survival factor in human mesenchymal stromal cells. Gene. vol 551. issue 2. 2014-12-09. PMID:25200494. |
this is an important novel finding, which suggests that wisp1 is indispensable for the protection of healthy hmscs against trail-induced apoptosis. |
2014-12-09 |
2023-08-13 |
human |
| Yan Chen Shang, Zhao Zhong Chong, Shaohui Wang, Kenneth Maies. Wnt1 inducible signaling pathway protein 1 (WISP1) targets PRAS40 to govern β-amyloid apoptotic injury of microglia. Current neurovascular research. vol 9. issue 4. 2013-10-17. PMID:22873724. |
we show that the ccn4 protein, wnt1 inducible signaling pathway protein 1 (wisp1), is initially up-regulated by aβ and can modulate its endogenous expression for the protection of microglia during aβ mediated apoptosis. |
2013-10-17 |
2023-08-12 |
Not clear |