| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Abhijit Dandapat, Chang Ping Hu, Jiawei Chen, Yong Liu, Junaid A Khan, Francesco Remeo, Robert M Carey, Paul L Hermonat, Jawahar L Meht. Over-expression of angiotensin II type 2 receptor (agtr2) decreases collagen accumulation in atherosclerotic plaque. Biochemical and biophysical research communications. vol 366. issue 4. 2008-02-05. PMID:18037370. |
at2r upregulation completely blocked the alterations in the expression of procollagen-i, osteopontin, fibronectin, cd68, and matrix metalloproteinases (mmp-2 and mmp-9), as well as phosphorylation of p38 and p44/42 mapks. |
2008-02-05 |
2023-08-12 |
mouse |
| Qiurong Ding, Ting Jin, Zhenzhen Wang, Yan Che. Catalase potentiates retinoic acid-induced THP-1 monocyte differentiation into macrophage through inhibition of peroxisome proliferator-activated receptor gamma. Journal of leukocyte biology. vol 81. issue 6. 2007-09-17. PMID:17369494. |
treatment of thp-1 cells with catalase was able to synergize with all-trans retinoic acid (atra) to enhance macrophage differentiation, demonstrated by changes of cell adherence, cell cycle arrest, nitroblue tetrazolium reduction, and expression of differentiation markers including cd68, cd11b, and matrix metalloproteinase 9 (mmp9). |
2007-09-17 |
2023-08-12 |
Not clear |
| Joseph Flores, Ivan L Cepeda, Michael L Cornfeldt, John R O'Kusky, Doris J Doude. Characterization and survival of long-term implants of human retinal pigment epithelial cells attached to gelatin microcarriers in a model of Parkinson disease. Journal of neuropathology and experimental neurology. vol 66. issue 7. 2007-08-31. PMID:17620984. |
rats were euthanized at 48 hours, 7 days, 4 weeks, and 5 months postimplant and immunohistochemically processed using the following antibodies: 1) human-specific nuclear mitotic apparatus protein (numa-ab2), 2) epithelial-specific extracellular matrix metalloproteinase inducer (emmprin), 3) rpe cell-specific rpe65, and the inflammation markers 4) glial fibrillary acidic protein and 5) ed1 (rat cd68). |
2007-08-31 |
2023-08-12 |
human |
| Hisham Alkhalidi, Danny Ghazaria. Cellular neurothekeoma with a plexiform morphology: a case report with a discussion of the plexiform lesions of the skin. Journal of cutaneous pathology. vol 34. issue 3. 2007-03-27. PMID:17302611. |
the immunohistochemistry shows diffuse reactivity to cd68, matrix metalloproteinase-ii, cd10 and pgp9.5 with focal reactivity to cd57 and cd34. |
2007-03-27 |
2023-08-12 |
Not clear |
| Raffaele Marfella, Michele D'Amico, Katherine Esposito, Alfonso Baldi, Clara Di Filippo, Mario Siniscalchi, Ferndinando Carlo Sasso, Michele Portoghese, Francesca Cirillo, Federico Cacciapuoti, Ornella Carbonara, Basilio Crescenzi, Feliciano Baldi, Antonio Ceriello, Giovanni Francesco Nicoletti, Francesco D'Andrea, Mario Verza, Ludovico Coppola, Francesco Rossi, Dario Giuglian. The ubiquitin-proteasome system and inflammatory activity in diabetic atherosclerotic plaques: effects of rosiglitazone treatment. Diabetes. vol 55. issue 3. 2006-04-19. PMID:16505224. |
plaques were analyzed for macrophages (cd68), t-cells (cd3), inflammatory cells (hla-dr), ubiquitin, proteasome 20s activity, nuclear factor (nf)-kappab, inhibitor of kappab (ikappab)-beta, tumor necrosis factor (tnf)-alpha, nitrotyrosine, matrix metalloproteinase (mmp)-9, and collagen content (immunohistochemistry and enzyme-linked immunosorbent assay). |
2006-04-19 |
2023-08-12 |
Not clear |
| Tohru Ikeda, Sachiko Seki, Masahiko Maki, Norio Noguchi, Toru Kawamura, Shigeki Arii, Toru Igari, Morio Koike, Katsuiku Hirokaw. Hepatocellular carcinoma with osteoclast-like giant cells: possibility of osteoclastogenesis by hepatocyte-derived cells. Pathology international. vol 53. issue 7. 2004-03-30. PMID:12828610. |
immunohistochemistry revealed the expression of almost all markers of osteoclasts: tartrate-resistant acid phosphatase, cd68, cd51, cd54 and matrix metalloprotease-9, in osteoclast-like giant cells in the tumor. |
2004-03-30 |
2023-08-12 |
Not clear |
| Wataru Yoshida, Miwa Uzuki, Akira Kurose, Masaaki Yoshida, Jun Nishida, Tadashi Shimamura, Takashi Sawa. Cell characterization of mononuclear and giant cells constituting pigmented villonodular synovitis. Human pathology. vol 34. issue 1. 2003-03-11. PMID:12605368. |
five methods were used for cell analysis: (1) enzyme-histochemistry for tartrate-resistant acid phosphatase (trap); (2) immunohistochemistry using antibodies for cd68, macrophage colony-stimulating factor (m-csf), mib-1, p53, p21, p16, and cathepsin-l (cath l); (3) tdt-mediated deoxyuridine triphosphate-biotin terminal end labeling (tunel) as a measure of apoptosis; (4) fluorescence-based polymerase chain reaction single-strand conformation polymorphism analyses (fpcr-sscp) to detect p53 gene mutations; and (5) in situ hybridization using gene-specific oligoprobes for matrix metalloproteinase (mmp)-2, mmp-9, receptor activator of nuclear factor kappab ligand (rankl), and calcitonin receptor (ctr). |
2003-03-11 |
2023-08-12 |
Not clear |
| F C Denison, S C Riley, C L Elliott, R W Kelly, A A Calder, H O Critchle. The effect of mifepristone administration on leukocyte populations, matrix metalloproteinases and inflammatory mediators in the first trimester cervix. Molecular human reproduction. vol 6. issue 6. 2000-07-25. PMID:10825372. |
after administration of mifepristone (6-24 h), there was an increase in immunostaining for leukocyte common antigen (cd45), neutrophil elastase, monocytes (cd68), and matrix metalloproteinases (mmp)-1, -8 and -9. |
2000-07-25 |
2023-08-12 |
Not clear |
| J B Cowland, N Borregaar. The individual regulation of granule protein mRNA levels during neutrophil maturation explains the heterogeneity of neutrophil granules. Journal of leukocyte biology. vol 66. issue 6. 2000-01-13. PMID:10614782. |
the mrna levels in relation to the maturation of the cells were determined by northern blot for the 12 matrix proteins myeloperoxidase, proteinase-3, elastase, defensin, lactoferrin, ngal, hcap-18, transcobalamin-i, sgp28, gelatinase, lysozyme, and serglycin and the 4 membrane proteins cd68, cd11b, n-formyl-methionyl-leucyl-phenylalanine receptor, and cd35. |
2000-01-13 |
2023-08-12 |
human |
| M Jeziorska, C McCollum, D E Woole. Observations on bone formation and remodelling in advanced atherosclerotic lesions of human carotid arteries. Virchows Archiv : an international journal of pathology. vol 433. issue 6. 1999-01-06. PMID:9870690. |
smooth muscle cells (alpha-actin positive) were often located around osteoid-like matrix, together with focal accumulations of macrophages (cd68 and ham56 positive). |
1999-01-06 |
2023-08-12 |
human |
| Y Matsui, M Maeda, W Nakagami, H Iwat. The involvement of matrix metalloproteinases and inflammation in lumbar disc herniation. Spine. vol 23. issue 8. 1998-06-22. PMID:9580952. |
surgically obtained herniated lumbar disc specimens were stained with hematoxylin-eosin or toluidine blue (for detection of proteoglycans) or were immunostained with monoclonal antibodies (cd68), antihuman interstitial collagenase (matrix metalloproteinase [mmp]-1) and antihuman stromelysin (mmp-3). |
1998-06-22 |
2023-08-12 |
Not clear |
| H Baba, Y Maezawa, N Furusawa, M Fukuda, K Uchida, Y Kokubo, S Imur. Herniated cervical intervertebral discs: histological and immunohistochemical characteristics. European journal of histochemistry : EJH. vol 41. issue 4. 1998-04-14. PMID:9491312. |
immunohistochemical studies using specific antibodies showed the presence of cells positive for matrix metalloproteinase-3 (chondrocytes), cd68 (macrophages and monocytes), and interleukin-1 beta (endothelial cells), in cervical disc hernias. |
1998-04-14 |
2023-08-12 |
Not clear |
| T N Blankenship, A C Ender. Trophoblast cell-mediated modifications to uterine spiral arteries during early gestation in the macaque. Acta anatomica. vol 158. issue 4. 1998-02-12. PMID:9416353. |
standard indirect immunoperoxidase methods were used to identify matrix metalloproteinases (mmp-1, mmp-3, mmp-9), cathepsin b, cathepsin d, platelet-endothelial cell adhesion molecule, cytokeratins, smooth muscle actin, cd68, and factor viii-related antigen. |
1998-02-12 |
2023-08-12 |
monkey |
| K Taguchi, T Hirano, K Iwasaki, H Sugihar. Reconstruction culture system simulating human synovium: a three-dimensional collagen gel culture of synoviocytes. Cell structure and function. vol 22. issue 4. 1998-02-10. PMID:9368718. |
immunohistochemically, the majority of cultured cells expressed cd68 and matrix metalloproteinase 3. |
1998-02-10 |
2023-08-12 |
human |