| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cheng Xue, Xiao-Hui Li, Hong-Qun Ding, Xin Qian, Meng-Yu Zhang, Kai Chen, Zi-Wei Wei, Ying Li, Jun-Hai Jia, Wei-Ning Zhan. Pyridoxine supplementation before puberty ameliorates MAM-induced cognitive and sensorimotor gating impairments. Metabolic brain disease. vol 40. issue 1. 2024-12-19. PMID:39699742. |
cannabinoid receptor interacting protein 1 (cnrip1) and cannabinoid receptor-1 (cb1r), which regulate memory, cognitive and motor activity, were detected in the prefrontal cortex (pfc) and hippocampus of the offspring rats, and the cell proliferation in the hippocampal dentate gyrus (dg) was also observed. |
2024-12-19 |
2024-12-21 |
rat |
| Cheng Xue, Xiao-Hui Li, Hong-Qun Ding, Xin Qian, Meng-Yu Zhang, Kai Chen, Zi-Wei Wei, Ying Li, Jun-Hai Jia, Wei-Ning Zhan. Pyridoxine supplementation before puberty ameliorates MAM-induced cognitive and sensorimotor gating impairments. Metabolic brain disease. vol 40. issue 1. 2024-12-19. PMID:39699742. |
these results indicate that prepuberty pyridoxine supplementation has a positive effect on the prevention of cognitive deficits and sensorimotor gating impairment in mam-induced schizophrenia-like rats, accompanied by changes in the cb1r and cnrip1 expression in pfc and hippocampus, as well as the regeneration of neurons in the dg region. |
2024-12-19 |
2024-12-21 |
rat |
| Xie Wang, Hong Chen, Xiaoyan Zhang, Nan Shao, Ze Chang, Daojun Xie, Juan Zhan. Therapeutic Targets and Natural Product Screening for Cognitive Impairments Associated with Ferroptosis in Wilson's Disease. The American journal of Chinese medicine. 2024-12-17. PMID:39686792. |
in the wd copper-loaded rat model, evaluations using the morris water maze (mwm), y maze, hematoxylin and eosin staining, transmission electron microscopy (tem), and immunofluorescence (if) detection showed that dg significantly enhanced cognitive function recovery, reduced structural damage to hippocampal neurons, and protected mitochondrial integrity. |
2024-12-17 |
2024-12-21 |
rat |
| Xie Wang, Hong Chen, Xiaoyan Zhang, Nan Shao, Ze Chang, Daojun Xie, Juan Zhan. Therapeutic Targets and Natural Product Screening for Cognitive Impairments Associated with Ferroptosis in Wilson's Disease. The American journal of Chinese medicine. 2024-12-17. PMID:39686792. |
this study elucidates the neuroprotective effect of dg on hippocampal neurons by activating the p38[formula: see text]-mediated fpt pathway, highlighting its efficacy as a potent monomer in traditional chinese medicine and illuminating its potential role in the clinical treatment of wdci. |
2024-12-17 |
2024-12-21 |
rat |
| Santiago Ronchetti, Florencia Labombarda, Julian Del Core, Paulina Roig, Alejandro F De Nicola, Luciana Pietraner. The phytoestrogen genistein improves hippocampal neurogenesis and cognitive impairment and decreases neuroinflammation in an animal model of metabolic syndrome. Journal of neuroendocrinology. 2024-12-16. PMID:39676329. |
expression of gfap was increased in the dg and ca1 areas of the hippocampus and treatment decreased astrogliosis in all of them. |
2024-12-16 |
2024-12-21 |
human |
| Lei Wu, Yan Sun, Zhangjie Wu, Ruiyi Liu, Ying Yin, Nga-Lee Wong, Wenzheng Ju, Hailou Zhan. A rich component of Fructus Aurantii, meranzin hydrate, exerts antidepressant effects via suppressing caspase4 to regulate glial cell and neuronal functions in the hippocampus. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 182. 2024-12-15. PMID:39675136. |
furthermore, mh could increase long-term potential (ltp) in the hippocampal dentate gyrus (dg) and activation of hippocampal caspase4 blocked mh's enhancement on neuronal activities and synaptic plasticity in the hippocampal dg. |
2024-12-15 |
2024-12-21 |
mouse |
| Xiujian Sun, Yexiang Chen, Ying Zhang, Tiantian Cheng, Huisheng Peng, Yanting Sun, Jing-Gen Liu, Chi X. Exosomes released from immature neurons regulate adult neural stem cell differentiation through microRNA-7a-5p. Stem cells (Dayton, Ohio). 2024-12-13. PMID:39670872. |
exosomes in the hippocampal dentate gyrus (dg) are essential for modulating the cell signaling controlling the neural differentiation of hippocampal neural stem cells (nscs), which may determine the level of hippocampal adult neurogenesis. |
2024-12-13 |
2024-12-22 |
mouse |
| Lei Tian, Jiang Chen, Xuan Liu, Yizhe Wei, Yiming Zhao, Yue Shi, Kang Li, Huanliang Liu, Wenqing Lai, Bencheng Li. Prenatal exposure on nanoplastics: a study of spatial transcriptomics in hippocampal offspring. Environmental pollution (Barking, Essex : 1987). 2024-12-07. PMID:39644950. |
moreover, the annotations of four hippocampus regions, ca1, ca2-3, dg, and hilus, as well as the go and gsva of several cell types, revealed deficiencies that can contribute to learning memory impairment. |
2024-12-07 |
2024-12-10 |
rat |
| Tahsin Nairuz, Jin-Chul Heo, Jong-Ha Le. Differential Glial Response and Neurodegenerative Patterns in CA1, CA3, and DG Hippocampal Regions of 5XFAD Mice. International journal of molecular sciences. vol 25. issue 22. 2024-11-27. PMID:39596222. |
differential glial response and neurodegenerative patterns in ca1, ca3, and dg hippocampal regions of 5xfad mice. |
2024-11-27 |
2024-11-29 |
mouse |
| Tahsin Nairuz, Jin-Chul Heo, Jong-Ha Le. Differential Glial Response and Neurodegenerative Patterns in CA1, CA3, and DG Hippocampal Regions of 5XFAD Mice. International journal of molecular sciences. vol 25. issue 22. 2024-11-27. PMID:39596222. |
in this study, the distinct patterns of glial response and neurodegeneration within the ca1, ca3, and dentate gyrus (dg) regions of the hippocampus were examined in 5xfad mice at 6 and 12 months of age. |
2024-11-27 |
2024-11-29 |
mouse |
| Xiaolin Zhong, Ling Chen, Yajuan Wang, Yue Liang, Yanmei Huang, Zuyao Chen, Wenyu Cao, Jianghua Liu, Xuyu Z. METTL14/YTHDC1-Mediated m6A Modification in Hippocampus Improves Pentylenetetrazol-Induced Acute Seizures. Molecular neurobiology. vol 61. issue 12. 2024-11-22. PMID:38814536. |
our results indicated that the level of m6a was declined significantly in the dentate gyrus (dg) of hippocampus of pentylenetetrazol (ptz)-induced seizure mice. |
2024-11-22 |
2024-11-24 |
mouse |
| Elizabeth A McDevitt, Ghootae Kim, Nicholas B Turk-Browne, Kenneth A Norma. The role of REM sleep in neural differentiation of memories in the hippocampus. bioRxiv : the preprint server for biology. 2024-11-18. PMID:39553942. |
while the predicted results were not observed in the preregistered left ca2/3/dg roi, we did observe evidence for our hypothesis in closely related hippocampal rois, uncorrected for multiple comparisons: in right ca2/3/dg, differentiation in the group with rem sleep was greater than in the groups without rem sleep (wake and non-rem nap); this differentiation was item-specific and concentrated in right dg. |
2024-11-18 |
2024-11-22 |
human |
| Charlotte C M Castillon, Shintaro Otsuka, John N Armstrong, Anis Contracto. Subregional activity in the dentate gyrus is amplified during elevated cognitive demands. bioRxiv : the preprint server for biology. 2024-11-18. PMID:39554113. |
prior work has demonstrated that there are differences in the activation of granule neurons in the supra and infrapyramidal blades of the dg during a range of hippocampal dependent tasks. |
2024-11-18 |
2024-11-22 |
mouse |
| Kelsey L Canada, Tracy Riggins, Simona Ghetti, Noa Ofen, Ana M Daughert. A data integration method for new advances in development cognitive neuroscience. Developmental cognitive neuroscience. vol 70. 2024-11-16. PMID:39549555. |
we identified commensurate measures of cornu ammonis (ca) 1, dentate gyrus (dg)/ca3, and subiculum (sub). |
2024-11-16 |
2024-11-20 |
Not clear |
| Isaac Vingan, Shwetha Phatarpekar, Victoria Sook Keng Tung, Alejandro Iván Hernández, Oleg V Evgrafov, Juan Marcos Alarco. Spatially resolved transcriptomic signatures of hippocampal subregions and Frontiers in molecular neuroscience. vol 17. 2024-11-15. PMID:39544521. |
we found that recall induced differentially expressed genes (degs) in the ca1 and ca3 hippocampal subregions were enriched with genes involved in synaptic transmission and synaptic plasticity, while degs in the dentate gyrus (dg) were enriched with genes involved in energy balance and ribosomal function. |
2024-11-15 |
2024-11-17 |
Not clear |
| Mahsa Mohammadi, Seyed Erfan Omidiani, Ronak Azizbeigi, Abbas Haghparas. Cannabidiol Plays a Modulatory Function on the Methamphetamine-Induced Reward Through Hippocampal D2-Like Dopamine Receptors. Neurochemical research. vol 50. issue 1. 2024-11-14. PMID:39540967. |
to shed light on the role of the d2-like dopamine receptor (d2r) in the hippocampal dentate gyrus (dg), the present study examined the effects of cbd on the acquisition and expression of the conditioned place preference (cpp) induced by meth. |
2024-11-14 |
2024-11-17 |
rat |
| Irene Martínez-Gallego, Heriberto Coatl-Cuaya, Antonio Rodriguez-Moren. Astrocytes mediate two forms of spike timing-dependent depression at entorhinal cortex-hippocampal synapses. eLife. vol 13. 2024-11-14. PMID:39541232. |
the entorhinal cortex (ec) connects to the hippocampus sending different information from cortical areas that is first processed at the dentate gyrus (dg) including spatial, limbic and sensory information. |
2024-11-14 |
2024-11-17 |
mouse |
| Linping Wang, Weiyao Wang, Yingshun Li, Hua Jin, Bin Xiao, Qinghua Ji. Dopamine and D1 receptor in hippocampal dentate gyrus involved in chronic stress-induced alteration of spatial learning and memory in rats. Neurobiology of stress. vol 33. 2024-11-14. PMID:39524935. |
however, the specific roles of da and d1r in the hippocampal dentate gyrus (dg), particularly in cs-induced changes in spatial learning and memory, are not well understood. |
2024-11-14 |
2024-11-17 |
rat |
| Lisa N Miller, Ashley E Walters, Jiyeon K Denninger, Meretta A Hanson, Alec H Marshall, Aidan C Johantges, Manal Hosawi, Gwendolyn Sebring, Joshua D Rieskamp, Tianli Ding, Raina Rindani, Kelly S Chen, Megan E Goldberg, Sakthi Senthilvelan, Abigail Volk, Fangli Zhao, Candice Askwith, Jason C Wester, Elizabeth D Kirb. Neural stem and progenitor cells support and protect adult hippocampal function via vascular endothelial growth factor secretion. Molecular psychiatry. 2024-11-11. PMID:39528687. |
adult neural stem and progenitor cells (nspcs) reside in the dentate gyrus (dg) of the hippocampus throughout the lifespan of most mammalian species. |
2024-11-11 |
2024-11-17 |
Not clear |
| Zhanghong Zhou, E Tian, Jun Wang, Zhaoqi Guo, Jingyu Chen, Jiaqi Guo, Shiyu Shi, Wandi Xu, Xixi Yu, Caijuan Qiao, Yuejin Zhang, Yisheng Lu, Sulin Zhan. Cognitive impairments and neurobiological changes induced by unilateral vestibular dysfunction in mice. Neurobiology of disease. 2024-10-31. PMID:39481811. |
immunofluorescence staining revealed enhanced activation of c-fos in the hippocampal dentate gyrus (dg) at various time points post-ul, suggesting a role of the hippocampus in cognitive deficits following uvl. |
2024-10-31 |
2024-11-03 |
mouse |