| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rocio Alfaro-Ruiz, Alejandro Martín-Belmonte, Carolina Aguado, Ana Esther Moreno-Martínez, Yugo Fukazawa, Rafael Lujá. Selective disruption of synaptic NMDA receptors of the hippocampal trisynaptic circuit in Aβ pathology. Biological research. vol 57. issue 1. 2024-08-23. PMID:39175009. |
using quantitative sds-frl, we unravelled the molecular organisation of glun1 in seven excitatory synapse populations at a high spatial resolution in the ca1 and ca3 fields and the dg of the hippocampus in 12-month-old app/ps1 mice. |
2024-08-23 |
2024-08-25 |
mouse |
| Keisuke Otsubo, Naoko Sakashita, Yuki Nishimoto, Yo Sato, Takehisa Tsutsui, Katsunori Kobayashi, Kanzo Suzuki, Eri Segi-Nishid. Role of desmoplakin in supporting neuronal activity, neurogenic processes, and emotional-related behaviors in the dentate gyrus. Frontiers in neuroscience. vol 18. 2024-08-23. PMID:39176381. |
dsp is specifically expressed in the hippocampal dentate gyrus (dg) in the central nervous system. |
2024-08-23 |
2024-08-25 |
mouse |
| Keisuke Otsubo, Naoko Sakashita, Yuki Nishimoto, Yo Sato, Takehisa Tsutsui, Katsunori Kobayashi, Kanzo Suzuki, Eri Segi-Nishid. Role of desmoplakin in supporting neuronal activity, neurogenic processes, and emotional-related behaviors in the dentate gyrus. Frontiers in neuroscience. vol 18. 2024-08-23. PMID:39176381. |
using an adeno-associated virus knockdown system in mice, we provide evidence that dsp in the dg maintains hippocampal functions, including neuronal activity and adult neurogenesis, and contributes to anxiolytic-like effects. |
2024-08-23 |
2024-08-25 |
mouse |
| Marie H Sabec, Quentin R Savage, John L Wood, Uwe Masko. Targeting high-affinity nicotinic receptors protects against the functional consequences of β-amyloid in mouse hippocampus. Molecular psychiatry. 2024-08-20. PMID:39164528. |
the hippocampus is affected early in the pathogenesis of ad, however the impact of soluble β-amyloid on the dentate gyrus (dg) subregion of the hippocampus and its interaction with nicotinic acetylcholine receptors (nachrs) within this region are not known. |
2024-08-20 |
2024-08-23 |
mouse |
| Rui Wang, Linzhong Zhang, Xia Wang, Wen Li, Tingliang Jian, Pengcheng Yin, Xinzhi Wang, Qianwei Chen, Xiaowei Chen, Han Qi. Electrophysiological activity pattern of mouse hippocampal CA1 and dentate gyrus under isoflurane anesthesia. Frontiers in cellular neuroscience. vol 18. 2024-08-06. PMID:39104439. |
the ca1 and dentate gyrus (dg), serving as the primary efferent and gateway of the hippocampal trisynaptic circuit facilitating cognitive learning and memory functions, exhibit significant differences in cellular composition, molecular makeup, and responses to various stimuli. |
2024-08-06 |
2024-08-08 |
mouse |
| Sang-Yoon Kim, Woochang Li. Effect of adult-born immature granule cells on pattern separation in the hippocampal dentate gyrus. Cognitive neurodynamics. vol 18. issue 4. 2024-08-06. PMID:39104672. |
young immature granule cells (imgcs) appear via adult neurogenesis in the hippocampal dentate gyrus (dg). |
2024-08-06 |
2024-08-08 |
Not clear |
| Qing Shang, Lizhi Zhang, Biao Xiao, Jianhong Yang, Jie Sun, Xiang Gao, Yi Huang, Zhengchun Wan. Juvenile Bright Light Exposure Ameliorates Adult Behavioral Abnormalities by Enhancing Neurogenesis in a N-methyl-D-aspartate Receptor Dysfunction Mouse Model Relevant for Cognitive Impairment in Schizophrenia. Behavioural brain research. 2024-07-24. PMID:39047873. |
long-term bright light treatment further promoted the differentiation of brdu+ cells into immature neurons (brdu+ dcx+ cells), mature neurons (brdu+ neun+ cells), or astrocytes (brdu+ gfap+ cells) in the hippocampal dg. |
2024-07-24 |
2024-07-28 |
mouse |
| Shu Xiao, Zibin Yang, Hong Yan, Guanmao Chen, Shuming Zhong, Pan Chen, Hui Zhong, Hengwen Yang, Yanbin Jia, Zhinan Yin, Jiaying Gong, Li Huang, Ying Wan. Gut proinflammatory bacteria is associated with abnormal functional connectivity of hippocampus in unmedicated patients with major depressive disorder. Translational psychiatry. vol 14. issue 1. 2024-07-16. PMID:39013880. |
severn pairs of hippocampus subregions (the bilateral cornu ammonis [ca1-ca3], dentate gyrus (dg), entorhinal cortex, hippocampal-amygdaloid transition area, and subiculum) were selected as the seeds in the functional connectivity (fc) analysis. |
2024-07-16 |
2024-07-19 |
human |
| Shu Xiao, Zibin Yang, Hong Yan, Guanmao Chen, Shuming Zhong, Pan Chen, Hui Zhong, Hengwen Yang, Yanbin Jia, Zhinan Yin, Jiaying Gong, Li Huang, Ying Wan. Gut proinflammatory bacteria is associated with abnormal functional connectivity of hippocampus in unmedicated patients with major depressive disorder. Translational psychiatry. vol 14. issue 1. 2024-07-16. PMID:39013880. |
compared with hcs, patients with mdd exhibited increased fc between the left hippocampus (ca2, ca3 and dg) and right hippocampus (ca2 and ca3), and decreased fc between the right hippocampal ca3 and bilateral posterior cingulate cortex. |
2024-07-16 |
2024-07-19 |
human |
| Wei-Li Chang, Rene He. Adult Neurogenesis, Context Encoding, and Pattern Separation: A Pathway for Treating Overgeneralization. Advances in neurobiology. vol 38. 2024-07-15. PMID:39008016. |
the integration of these new neurons into the dentate gyrus (dg) has implications for memory encoding, with unique firing and wiring properties of immature neurons that affect how the hippocampal network encodes and stores attributes of memory. |
2024-07-15 |
2024-07-18 |
Not clear |
| Xinyu Zou, Qian Tang, Ryota Ojiro, Shunsuke Ozawa, Momoka Shobudani, Yuri Sakamaki, Yuri Ebizuka, Meilan Jin, Toshinori Yoshida, Makoto Shibutan. Increased spontaneous activity and progressive suppression of adult neurogenesis in the hippocampus of rat offspring after maternal exposure to imidacloprid. Chemico-biological interactions. 2024-07-13. PMID:39002876. |
the present study investigated the effects of maternal exposure to imi on behaviors and adult neurogenesis in the hippocampal dentate gyrus (dg) of rat offspring. |
2024-07-13 |
2024-07-16 |
rat |
| Xinyu Zou, Qian Tang, Ryota Ojiro, Shunsuke Ozawa, Momoka Shobudani, Yuri Sakamaki, Yuri Ebizuka, Meilan Jin, Toshinori Yoshida, Makoto Shibutan. Increased spontaneous activity and progressive suppression of adult neurogenesis in the hippocampus of rat offspring after maternal exposure to imidacloprid. Chemico-biological interactions. 2024-07-13. PMID:39002876. |
imi decreased hippocampal acetylcholinesterase activity and chrnb2 transcript levels in the dg on weaning and in adulthood. |
2024-07-13 |
2024-07-16 |
rat |
| Frederike Schäfer, Archana Tomar, Shogo Sato, Raffaele Teperino, Axel Imhof, Shibojyoti Lahir. Enhanced in situ spatial proteomics by effective combination of MALDI imaging and LC-MS/MS. Molecular & cellular proteomics : MCP. 2024-07-12. PMID:38996918. |
as an example, we identified the groups of proteins distinguishing the neuronal populations of dentate gyrus (dg) and the cornu ammonis (ca) in the same brain section. |
2024-07-12 |
2024-07-15 |
mouse |
| Wenyan Zhao, Wei Zhang, Yingying Hu, Yuliang Zhou, Jinying Zhao, Yahong Li, Zhipeng X. AdipoRon Ameliorates Synaptic Dysfunction and Inhibits tau Hyperphosphorylation through the AdipoR/AMPK/mTOR Pathway in T2DM Mice. Neurochemical research. vol 49. issue 8. 2024-07-09. PMID:38819697. |
in addition, adiporon treatment up-regulated synaptic proteins (psd95, syn, gap43, and syp), increased the number of hippocampal synapses and attenuated synaptic damage, including the length, the number and the density of dendritic spines in ca1 and dg regions. |
2024-07-09 |
2024-07-12 |
mouse |
| Dongpei Zhuang, Nan Yu, Shuo Han, Xinyao Zhang, Chuanxia J. The Kv7 channel opener Retigabine reduces neuropathology and alleviates behavioral deficits in APP/PS1 transgenic mice. Behavioural brain research. vol 471. 2024-07-09. PMID:38971432. |
rtg could also ameliorate damage to the nissl bodies in cortex and hippocampal ca and dg regions in 9-month-old app/ps1 mice. |
2024-07-09 |
2024-07-12 |
mouse |
| Satoshi Deyama, Masabumi Minami, Katsuyuki Kaned. [Resolvin E1 as a potential lead for the treatment of depression]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 159. issue 4. 2024-06-30. PMID:38945902. |
local infusion of rve1 into the medial prefrontal cortex (mpfc) or dorsal hippocampal dentate gyrus (dg) also produces antidepressant-like effects, suggesting that these brain regions are sites of action of rve1. |
2024-06-30 |
2024-07-03 |
mouse |
| Alexandra Gros, Fandilla Marie Furlan, Vanessa Rouglan, Alexandre Favereaux, Bruno Bontempi, Jean-Luc More. Physical exercise restores adult neurogenesis deficits induced by simulated microgravity. NPJ microgravity. vol 10. issue 1. 2024-06-21. PMID:38906877. |
we studied the proliferation, survival and maturation of newborn cells in the following neurogenic niches: the subventricular zone (svz)/olfactory bulb (ob) and the dentate gyrus (dg) of the hippocampus, at different delays following various periods of smg. |
2024-06-21 |
2024-06-24 |
rat |
| Ivette Espinoza, Francisco Cabrera, Julio César Morales-Medina, Ma de Jesús Gómez-Villalobos, Gonzalo Flore. The administration of Cerebrolysin elicits neuroprotective and neurorepair effects in an animal model of type 1 diabetes mellitus. Behavioural brain research. 2024-06-19. PMID:38897418. |
this research aims to investigate the neuroprotective and neurorepair effect of cbl on the cytoarchitecture of neurons and spine density in pyramidal neurons of the prefrontal (pfc) and the ca1 region of the dorsal hippocampus, as well as spheroidal neurons of the dentate gyrus (dg), in stz-induced dm. |
2024-06-19 |
2024-06-22 |
rat |
| Ivette Espinoza, Francisco Cabrera, Julio César Morales-Medina, Ma de Jesús Gómez-Villalobos, Gonzalo Flore. The administration of Cerebrolysin elicits neuroprotective and neurorepair effects in an animal model of type 1 diabetes mellitus. Behavioural brain research. 2024-06-19. PMID:38897418. |
in the first experimental condition, cbl treatment preserved the neuronal morphology in pfc layer 3, pfc layer 5 and the dg of the hippocampus, while also maintaining spine density in the pfc-3, dg and ca1 hippocampus. |
2024-06-19 |
2024-06-22 |
rat |
| Ivette Espinoza, Francisco Cabrera, Julio César Morales-Medina, Ma de Jesús Gómez-Villalobos, Gonzalo Flore. The administration of Cerebrolysin elicits neuroprotective and neurorepair effects in an animal model of type 1 diabetes mellitus. Behavioural brain research. 2024-06-19. PMID:38897418. |
furthermore, cbl induced neurorepair in neurons within the pfc-3, pfc-5 and ca1 regions of the hippocampus, along with an increase in spine density in the pfc-3, dg and ca1 hippocampus. |
2024-06-19 |
2024-06-22 |
rat |