| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiuting Qi, Xi Chen, Qi Luo, Lihan Liu, Dong An, Sha Sha, Yimei Du, Chunfeng Wu, Lei Che. TRPV4 Blockage Inhibits the Neurogenesis in the Adult Hippocampal Dentate Gyrus Following Pilocarpine‑Induced Status Epilepticus. Molecular neurobiology. 2024-09-23. PMID:39312069. |
herein, administration of a trpv4-specific antagonist, hc-067047, attenuated the enhanced neural stem cell proliferation in the adult hippocampal dg in mice following pilocarpine‑induced status epilepticus (pise). |
2024-09-23 |
2024-09-26 |
mouse |
| Nicole M Weston, Jakob C Green, Timothy N Keoprasert, Dong Su. Dendritic morphological development of traumatic brain injury-induced new neurons in the dentate gyrus is important for post-injury cognitive recovery and is regulated by Notch1. Experimental neurology. 2024-09-20. PMID:39303845. |
it is well established that neurogenesis in the dentate gyrus (dg) of the hippocampus is important for hippocampal dependent learning and memory functions. |
2024-09-20 |
2024-09-23 |
mouse |
| J J Rodríguez, E Gardenal, F Zallo, J Cabot, X Busquet. Early PSA-NCAM reduction in the dentate gyrus and impaired plasticity in the Alzheimer´s disease 3xTg-mice model. Acta histochemica. vol 126. issue 8. 2024-09-17. PMID:39288682. |
neurodegenerative diseases such as alzheimer´s (ad) and physiological ageing are characterized by a decline in neurogenesis and in the polysialylated isoforms of neural cell adhesion molecule (psa-ncam) expression within the hippocampus and specifically in the dentate gyrus (dg). |
2024-09-17 |
2024-09-20 |
mouse |
| Adam Hamed, Miron Bartosz Kursa, Wiktoria Mrozek, Krzysztof Piotr Piwoński, Monika Falińska, Konrad Danielewski, Emilia Rejmak, Urszula Włodkowska, Stepan Kubik, Rafał Czajkowsk. Spatio-temporal mechanisms of consolidation, recall and reconsolidation in reward-related memory trace. Molecular psychiatry. 2024-09-13. PMID:39271752. |
by employing machine learning analysis, we have shown this pattern is especially pronounced in the vta; furthermore, we also uncovered significant activity patterns in retrosplenial and prefrontal cortices, as well as in the dg and ca3 subfields of the hippocampus. |
2024-09-13 |
2024-09-16 |
Not clear |
| Jacopo Agrimi, Lucia Bernardele, Naeem Sbaiti, Marco Brondi, Donato D'Angelo, Marta Canato, Ivan Marchionni, Christian U Oeing, Giussy Barbara, Beatrice Vignoli, Marco Canossa, Nina Kaludercic, Gaya Spolverato, Anna Raffaello, Claudia Lodovichi, Marco Dal Maschio, Nazareno Paolocc. Reiterated male-to-female violence disrupts hippocampal estrogen receptor β expression, prompting anxiety-like behavior. iScience. vol 27. issue 9. 2024-09-04. PMID:39228787. |
rmfvi prompted anxiety-like behavior in female mice whose hippocampus displayed a marked neuronal loss and hampered neurogenesis, namely reduced brdu-dcx-positive nuclei and diminished dendritic arborization in the dentate gyrus (dg): effects paralleled by a substantial downregulation of the estrogen receptor β (erβ). |
2024-09-04 |
2024-09-06 |
mouse |
| Reihaneh Mohammadkhani, Iraj Salehi, Samaneh Safari, Reza Ghahremani, Alireza Komaki, Seyed Asaad Karim. Continuous exercise training rescues hippocampal long-term potentiation in the VPA rat model of Autism: Uncovering sex-specific effects. Neuroscience. 2024-08-30. PMID:39214164. |
the aim of the present study was to investigate the effects of interval training (it) and continuous training (ct) exercises on ltp in the hippocampal dentate gyrus (dg) neurons of valproic acid (vpa) rat model of autism. |
2024-08-30 |
2024-09-04 |
rat |
| Shenjia Gao, Ruling Shen, Jie Li, Yi Jiang, Hao Sun, Xinyi Wu, Xiya Li, Changhong Miao, Miao He, Jun Wang, Wankun Che. N-acetyltransferase 10 mediates cognitive dysfunction through the acetylation of GABA Proceedings of the National Academy of Sciences of the United States of America. vol 121. issue 36. 2024-08-27. PMID:39190359. |
our findings demonstrate that clp significantly upregulates nat10 expression and mrna acetylation in the excitatory neurons of the hippocampal dentate gyrus (dg). |
2024-08-27 |
2024-08-30 |
mouse |
| Zhengshan Liu, Yu H Sun, Yue Ren, Jessica Marie Perez, Daniel Scott, Carol Tamming. Upregulated solute-carrier family genes in the hippocampus of schizophrenia can be rescued by antipsychotic medications. Schizophrenia research. vol 272. 2024-08-25. PMID:39182310. |
our previous studies have found that functional changes in the hippocampal circuit from dentate gyrus (dg) to cornu ammonis 3 and 1 (ca3, ca1) are highly associated with schizophrenia (sz). |
2024-08-25 |
2024-08-28 |
human |
| Rocio Alfaro-Ruiz, Alejandro Martín-Belmonte, Carolina Aguado, Ana Esther Moreno-Martínez, Yugo Fukazawa, Rafael Lujá. Selective disruption of synaptic NMDA receptors of the hippocampal trisynaptic circuit in Aβ pathology. Biological research. vol 57. issue 1. 2024-08-23. PMID:39175009. |
using quantitative sds-frl, we unravelled the molecular organisation of glun1 in seven excitatory synapse populations at a high spatial resolution in the ca1 and ca3 fields and the dg of the hippocampus in 12-month-old app/ps1 mice. |
2024-08-23 |
2024-08-25 |
mouse |
| Keisuke Otsubo, Naoko Sakashita, Yuki Nishimoto, Yo Sato, Takehisa Tsutsui, Katsunori Kobayashi, Kanzo Suzuki, Eri Segi-Nishid. Role of desmoplakin in supporting neuronal activity, neurogenic processes, and emotional-related behaviors in the dentate gyrus. Frontiers in neuroscience. vol 18. 2024-08-23. PMID:39176381. |
dsp is specifically expressed in the hippocampal dentate gyrus (dg) in the central nervous system. |
2024-08-23 |
2024-08-25 |
mouse |
| Keisuke Otsubo, Naoko Sakashita, Yuki Nishimoto, Yo Sato, Takehisa Tsutsui, Katsunori Kobayashi, Kanzo Suzuki, Eri Segi-Nishid. Role of desmoplakin in supporting neuronal activity, neurogenic processes, and emotional-related behaviors in the dentate gyrus. Frontiers in neuroscience. vol 18. 2024-08-23. PMID:39176381. |
using an adeno-associated virus knockdown system in mice, we provide evidence that dsp in the dg maintains hippocampal functions, including neuronal activity and adult neurogenesis, and contributes to anxiolytic-like effects. |
2024-08-23 |
2024-08-25 |
mouse |
| Marie H Sabec, Quentin R Savage, John L Wood, Uwe Masko. Targeting high-affinity nicotinic receptors protects against the functional consequences of β-amyloid in mouse hippocampus. Molecular psychiatry. 2024-08-20. PMID:39164528. |
the hippocampus is affected early in the pathogenesis of ad, however the impact of soluble β-amyloid on the dentate gyrus (dg) subregion of the hippocampus and its interaction with nicotinic acetylcholine receptors (nachrs) within this region are not known. |
2024-08-20 |
2024-08-23 |
mouse |
| Rui Wang, Linzhong Zhang, Xia Wang, Wen Li, Tingliang Jian, Pengcheng Yin, Xinzhi Wang, Qianwei Chen, Xiaowei Chen, Han Qi. Electrophysiological activity pattern of mouse hippocampal CA1 and dentate gyrus under isoflurane anesthesia. Frontiers in cellular neuroscience. vol 18. 2024-08-06. PMID:39104439. |
the ca1 and dentate gyrus (dg), serving as the primary efferent and gateway of the hippocampal trisynaptic circuit facilitating cognitive learning and memory functions, exhibit significant differences in cellular composition, molecular makeup, and responses to various stimuli. |
2024-08-06 |
2024-08-08 |
mouse |
| Sang-Yoon Kim, Woochang Li. Effect of adult-born immature granule cells on pattern separation in the hippocampal dentate gyrus. Cognitive neurodynamics. vol 18. issue 4. 2024-08-06. PMID:39104672. |
young immature granule cells (imgcs) appear via adult neurogenesis in the hippocampal dentate gyrus (dg). |
2024-08-06 |
2024-08-08 |
Not clear |
| Qing Shang, Lizhi Zhang, Biao Xiao, Jianhong Yang, Jie Sun, Xiang Gao, Yi Huang, Zhengchun Wan. Juvenile Bright Light Exposure Ameliorates Adult Behavioral Abnormalities by Enhancing Neurogenesis in a N-methyl-D-aspartate Receptor Dysfunction Mouse Model Relevant for Cognitive Impairment in Schizophrenia. Behavioural brain research. 2024-07-24. PMID:39047873. |
long-term bright light treatment further promoted the differentiation of brdu+ cells into immature neurons (brdu+ dcx+ cells), mature neurons (brdu+ neun+ cells), or astrocytes (brdu+ gfap+ cells) in the hippocampal dg. |
2024-07-24 |
2024-07-28 |
mouse |
| Shu Xiao, Zibin Yang, Hong Yan, Guanmao Chen, Shuming Zhong, Pan Chen, Hui Zhong, Hengwen Yang, Yanbin Jia, Zhinan Yin, Jiaying Gong, Li Huang, Ying Wan. Gut proinflammatory bacteria is associated with abnormal functional connectivity of hippocampus in unmedicated patients with major depressive disorder. Translational psychiatry. vol 14. issue 1. 2024-07-16. PMID:39013880. |
severn pairs of hippocampus subregions (the bilateral cornu ammonis [ca1-ca3], dentate gyrus (dg), entorhinal cortex, hippocampal-amygdaloid transition area, and subiculum) were selected as the seeds in the functional connectivity (fc) analysis. |
2024-07-16 |
2024-07-19 |
human |
| Shu Xiao, Zibin Yang, Hong Yan, Guanmao Chen, Shuming Zhong, Pan Chen, Hui Zhong, Hengwen Yang, Yanbin Jia, Zhinan Yin, Jiaying Gong, Li Huang, Ying Wan. Gut proinflammatory bacteria is associated with abnormal functional connectivity of hippocampus in unmedicated patients with major depressive disorder. Translational psychiatry. vol 14. issue 1. 2024-07-16. PMID:39013880. |
compared with hcs, patients with mdd exhibited increased fc between the left hippocampus (ca2, ca3 and dg) and right hippocampus (ca2 and ca3), and decreased fc between the right hippocampal ca3 and bilateral posterior cingulate cortex. |
2024-07-16 |
2024-07-19 |
human |
| Wei-Li Chang, Rene He. Adult Neurogenesis, Context Encoding, and Pattern Separation: A Pathway for Treating Overgeneralization. Advances in neurobiology. vol 38. 2024-07-15. PMID:39008016. |
the integration of these new neurons into the dentate gyrus (dg) has implications for memory encoding, with unique firing and wiring properties of immature neurons that affect how the hippocampal network encodes and stores attributes of memory. |
2024-07-15 |
2024-07-18 |
Not clear |
| Xinyu Zou, Qian Tang, Ryota Ojiro, Shunsuke Ozawa, Momoka Shobudani, Yuri Sakamaki, Yuri Ebizuka, Meilan Jin, Toshinori Yoshida, Makoto Shibutan. Increased spontaneous activity and progressive suppression of adult neurogenesis in the hippocampus of rat offspring after maternal exposure to imidacloprid. Chemico-biological interactions. 2024-07-13. PMID:39002876. |
the present study investigated the effects of maternal exposure to imi on behaviors and adult neurogenesis in the hippocampal dentate gyrus (dg) of rat offspring. |
2024-07-13 |
2024-07-16 |
rat |
| Xinyu Zou, Qian Tang, Ryota Ojiro, Shunsuke Ozawa, Momoka Shobudani, Yuri Sakamaki, Yuri Ebizuka, Meilan Jin, Toshinori Yoshida, Makoto Shibutan. Increased spontaneous activity and progressive suppression of adult neurogenesis in the hippocampus of rat offspring after maternal exposure to imidacloprid. Chemico-biological interactions. 2024-07-13. PMID:39002876. |
imi decreased hippocampal acetylcholinesterase activity and chrnb2 transcript levels in the dg on weaning and in adulthood. |
2024-07-13 |
2024-07-16 |
rat |