| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J M Zhang, L Tonelli, W T Regenold, M M McCarth. Effects of neonatal flutamide treatment on hippocampal neurogenesis and synaptogenesis correlate with depression-like behaviors in preadolescent male rats. Neuroscience. vol 169. issue 1. 2011-03-04. PMID:20399256. |
compared to vehicle controls, flutamide treatment significantly decreased (1) the number of microtubule-associated protein-2+ (map-2) neurons in the ca1 region, (2) the number of map-2+ neurons in the dentate gyrus (dg) region of the hippocampus, and (3) the density of dendritic spines of pyramidal neurons in the ca1 region. |
2011-03-04 |
2023-08-12 |
human |
| Jun Guo, Caiyong Yu, Hongzeng Li, Fangfang Liu, Rui Feng, Hui Wang, Yanling Meng, Zhuyi Li, Gong Ju, Jian Wan. Impaired neural stem/progenitor cell proliferation in streptozotocin-induced and spontaneous diabetic mice. Neuroscience research. vol 68. issue 4. 2011-03-02. PMID:20832431. |
accumulating evidence indicates that diabetes, regardless of its type, impairs adult neurogenesis in the dentate gyrus (dg) of the hippocampus (hpc). |
2011-03-02 |
2023-08-12 |
mouse |
| Takuya Yamamuro, Kouji Senzaki, Satomi Iwamoto, Yoshimi Nakagawa, Takashi Hayashi, Miyo Hori, Shigeko Sakamoto, Kazuo Murakami, Takashi Shiga, Osamu Urayam. Neurogenesis in the dentate gyrus of the rat hippocampus enhanced by tickling stimulation with positive emotion. Neuroscience research. vol 68. issue 4. 2011-03-02. PMID:20851720. |
in this study, we examined the effect of tactile stimulation (tickling), which induced positive emotion, on neurogenesis in the dentate gyrus (dg) of the hippocampus. |
2011-03-02 |
2023-08-12 |
rat |
| Roland A Bender, Lepu Zhou, Wiebke Wilkars, Lars Fester, Jan-Simon Lanowski, Danny Paysen, Almut König, Gabriele M Run. Roles of 17ß-estradiol involve regulation of reelin expression and synaptogenesis in the dentate gyrus. Cerebral cortex (New York, N.Y. : 1991). vol 20. issue 12. 2011-03-01. PMID:20421250. |
studies on the role of 17β-estradiol (e2) in the hippocampus have mainly focused on ca1 and ca3 regions, whereas in dentate gyrus (dg), its role is largely unknown. |
2011-03-01 |
2023-08-12 |
mouse |
| Roland A Bender, Lepu Zhou, Wiebke Wilkars, Lars Fester, Jan-Simon Lanowski, Danny Paysen, Almut König, Gabriele M Run. Roles of 17ß-estradiol involve regulation of reelin expression and synaptogenesis in the dentate gyrus. Cerebral cortex (New York, N.Y. : 1991). vol 20. issue 12. 2011-03-01. PMID:20421250. |
vice versa, inhibition of aromatase activity by letrozole resulted in reduced reelin expression, suggesting that e2 deriving from hippocampal sources contributes to the regulation of reelin as well as to the maintenance of spine synapses in dg. |
2011-03-01 |
2023-08-12 |
mouse |
| Peifei Gu, Yue Li, Yu Shang, Yue Hou, Songyan Zha. Proliferation changes in dentate gyrus of hippocampus during the first week following kainic acid-induced seizures. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. vol 130. issue 12. 2011-02-24. PMID:21139403. |
therefore, the rapid changes in the dg might be having a potential for hippocampus neuroplastic function. |
2011-02-24 |
2023-08-12 |
mouse |
| Joong-Sun Kim, Miyoung Yang, Hyosun Jang, Heejin Oui, Sung-Ho Kim, Taekyun Shin, Won-Suk Jang, Seung-Sook Lee, Changjong Moo. Granulocyte-colony stimulating factor ameliorates irradiation-induced suppression of hippocampal neurogenesis in adult mice. Neuroscience letters. vol 486. issue 1. 2011-02-16. PMID:20854880. |
acute exposure to cranial irradiation (5gy γ-rays) induced neural apoptosis and inhibited neurogenesis in the dentate gyrus (dg) of the adult mouse hippocampus. |
2011-02-16 |
2023-08-12 |
mouse |
| Joong-Sun Kim, Miyoung Yang, Hyosun Jang, Heejin Oui, Sung-Ho Kim, Taekyun Shin, Won-Suk Jang, Seung-Sook Lee, Changjong Moo. Granulocyte-colony stimulating factor ameliorates irradiation-induced suppression of hippocampal neurogenesis in adult mice. Neuroscience letters. vol 486. issue 1. 2011-02-16. PMID:20854880. |
pretreatment with g-csf (100μg/kg every 12h subcutaneously on three consecutive days) attenuated neural apoptosis and decreased the number of ki-67- and dcx-positive cells in the dg of the irradiated mouse hippocampus. |
2011-02-16 |
2023-08-12 |
mouse |
| Bart P F Rutten, Ivona Brasnjevic, Harry W M Steinbusch, Christoph Schmit. Caloric restriction and aging but not overexpression of SOD1 affect hippocampal volumes in mice. Mechanisms of ageing and development. vol 131. issue 9. 2011-02-02. PMID:20728464. |
the hippocampus and its subregions dentate gyrus (dg), ca3 and ca1-2 show vulnerability to aging, with hippocampal volume alterations as a measurable sign. |
2011-02-02 |
2023-08-12 |
mouse |
| Bart P F Rutten, Ivona Brasnjevic, Harry W M Steinbusch, Christoph Schmit. Caloric restriction and aging but not overexpression of SOD1 affect hippocampal volumes in mice. Mechanisms of ageing and development. vol 131. issue 9. 2011-02-02. PMID:20728464. |
aging reduced the mean volume of the entire hippocampus (-9.5%), grey (-8.7%) and white matter (-9.7%), and ca3 subregion (-13.6%), but not dg or ca1-2 subregion. |
2011-02-02 |
2023-08-12 |
mouse |
| Eva C Bunk, Hans-Georg König, Helena P Bonner, Brian P Kirby, Jochen H M Preh. NMDA-induced injury of mouse organotypic hippocampal slice cultures triggers delayed neuroblast proliferation in the dentate gyrus: an in vitro model for the study of neural precursor cell proliferation. Brain research. vol 1359. 2011-01-25. PMID:20478273. |
we present a model for the study of injury-induced neurogenesis in the dentate gyrus (dg) in murine organotypic hippocampal slice cultures (ohcs). |
2011-01-25 |
2023-08-12 |
mouse |
| Eva C Bunk, Hans-Georg König, Helena P Bonner, Brian P Kirby, Jochen H M Preh. NMDA-induced injury of mouse organotypic hippocampal slice cultures triggers delayed neuroblast proliferation in the dentate gyrus: an in vitro model for the study of neural precursor cell proliferation. Brain research. vol 1359. 2011-01-25. PMID:20478273. |
5-bromo-2-deoxyuridine (brdu)-labelling of the ohcs for three days subsequent to the nmda exposure revealed significantly increased brdu incorporation within the dg (sgz and gcl) of the hippocampus. |
2011-01-25 |
2023-08-12 |
mouse |
| Raphaël Poirier, Inge Veltman, Marie Claire Pflimlin, Frédéric Knoflach, Friedrich Metzge. Enhanced dentate gyrus synaptic plasticity but reduced neurogenesis in a mouse model of amyloidosis. Neurobiology of disease. vol 40. issue 2. 2011-01-12. PMID:20615468. |
long-term potentiation (ltp) and neurogenesis in the dentate gyrus (dg) are correlated forms of hippocampal plasticity which share, under physiological conditions, common regulatory mechanisms. |
2011-01-12 |
2023-08-12 |
mouse |
| Yangling Mu, Star W Lee, Fred H Gag. Signaling in adult neurogenesis. Current opinion in neurobiology. vol 20. issue 4. 2011-01-06. PMID:20471243. |
neural stem cells (nscs) in the adult brain continuously supply new neurons to the hippocampal dentate gyrus (dg) and the olfactory bulb (ob). |
2011-01-06 |
2023-08-12 |
Not clear |
| Nanthia A Suthana, Allison Krupa, Markus Donix, Alison Burggren, Arne D Ekstrom, Michael Jones, Linda M Ercoli, Karen J Miller, Prabha Siddarth, Gary W Small, Susan Y Bookheime. Reduced hippocampal CA2, CA3, and dentate gyrus activity in asymptomatic people at genetic risk for Alzheimer's disease. NeuroImage. vol 53. issue 3. 2011-01-03. PMID:20005961. |
in this study, we used high-resolution functional mri in apoe-4 carriers and non-carriers to measure activity in hippocampal subregions (ca fields 1, 2, 3; dentate gyrus [dg], and subiculum) and adjacent medial temporal lobe (parahippocampal and entorhinal) subregions. |
2011-01-03 |
2023-08-12 |
human |
| Henry A Nasrallah, Tracy Hopkins, Sarah K Pixle. Differential effects of antipsychotic and antidepressant drugs on neurogenic regions in rats. Brain research. vol 1354. 2011-01-03. PMID:20682307. |
bromodeoxyuridine (brdu) was injected to label dividing cells and positive cells were quantified in the oe, cortical svz, and dentate gyrus (dg) of the hippocampus. |
2011-01-03 |
2023-08-12 |
human |
| Cristiano Mendes da Silva, Luciano Gonçalves, Raul Manhaes-de-Castro, Maria Inês Nogueir. Postnatal fluoxetine treatment affects the development of serotonergic neurons in rats. Neuroscience letters. vol 483. issue 3. 2010-12-22. PMID:20696211. |
the goal of the present study was to investigate morphological changes in the serotonergic neurons/terminals in the dorsal (dr) and median (mnr) raphe nuclei and on the hippocampal dentate gyrus (dg) in neonatal rats treated from the 1st to the 21st postnatal day with fluoxetine (10 mg/kg sc, daily) or drug vehicle (0.9% saline 1 ml/kg). |
2010-12-22 |
2023-08-12 |
rat |
| Joana Gil-Mohapel, Fanny Boehme, Leah Kainer, Brian R Christi. Hippocampal cell loss and neurogenesis after fetal alcohol exposure: insights from different rodent models. Brain research reviews. vol 64. issue 2. 2010-12-20. PMID:20471420. |
the dentate gyrus (dg) of the hippocampus is one of the few brain regions where neurogenesis continues into adulthood. |
2010-12-20 |
2023-08-12 |
Not clear |
| Rosalia Crupi, Emanuela Mazzon, Angela Marino, Giuseppina La Spada, Placido Bramanti, Salvatore Cuzzocrea, Edoardo Spin. Melatonin treatment mimics the antidepressant action in chronic corticosterone-treated mice. Journal of pineal research. vol 49. issue 2. 2010-12-17. PMID:20536684. |
cell proliferation in hippocampal dentate gyrus (dg) was investigated by 5-bromo-2'-deoxyuridine and doublecortin immunohistochemistry techniques, and stereological procedure was used to quantify labeled cells. |
2010-12-17 |
2023-08-12 |
mouse |
| Yoshinobu Hara, Tadashi Nomura, Kaichi Yoshizaki, Jonas Frisén, Noriko Osum. Impaired hippocampal neurogenesis and vascular formation in ephrin-A5-deficient mice. Stem cells (Dayton, Ohio). vol 28. issue 5. 2010-12-02. PMID:20474079. |
the hippocampal dentate gyrus (dg) is one of the major regions of the adult neurogenesis, where neural stem/progenitor cells continuously generate new granule neurons, although molecular mechanisms underlying generation and maintenance of newly born neurons are still elusive. |
2010-12-02 |
2023-08-12 |
mouse |