Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Sergi Papiol, Daniel Keeser, Alkomiet Hasan, Thomas Schneider-Axmann, Florian Raabe, Franziska Degenhardt, Moritz J Rossner, Heike Bickeböller, Ludovico Cantuti-Castelvetri, Mikael Simons, Thomas Wobrock, Andrea Schmitt, Berend Malchow, Peter Falka. Polygenic burden associated to oligodendrocyte precursor cells and radial glia influences the hippocampal volume changes induced by aerobic exercise in schizophrenia patients. Translational psychiatry. vol 9. issue 1. 2020-08-05. PMID:31712617. |
hippocampal volume decrease is a structural hallmark of schizophrenia (scz), and convergent evidence from postmortem and imaging studies suggests that it may be explained by changes in the cytoarchitecture of the cornu ammonis 4 (ca4) and dentate gyrus (dg) subfields. |
2020-08-05 |
2023-08-13 |
Not clear |
Muhammad Tahir Khan, Jan Deussing, Yong Tang, Peter Ille. Astrocytic rather than neuronal P2X7 receptors modulate the function of the tri-synaptic network in the rodent hippocampus. Brain research bulletin. vol 151. 2020-08-04. PMID:30098388. |
whole-cell patch clamp recordings demonstrated that in the dentate gyrus (dg) as well as in the ca3 area of mouse hippocampal slices the prototypic p2x7 receptor (r) agonist dibenzoyl-atp (bz-atp) induced inward current responses both in neurons and astrocytes. |
2020-08-04 |
2023-08-13 |
mouse |
Alan Bo Han He, Chung Lei Huang, Anna Kozłowska, Jun Chien Chen, Chi-Wen Wu, Andrew Chih Wei Huang, Yu Qin Li. Involvement of neural substrates in reward and aversion to methamphetamine addiction: Testing the reward comparison hypothesis and the paradoxical effect hypothesis of abused drugs. Neurobiology of learning and memory. vol 166. 2020-07-28. PMID:31521799. |
the c-fos or p-erk immunohistochemical activity showed that the cingulated cortex area 1 (cg1), infralimbic cortex (il), prelimbic cortex (prl), basolateral amygdala (bla), nucleus accumbens (nac), and dentate gyrus (dg) of the hippocampus were overexpressed in aversive cta induced by methamphetamine. |
2020-07-28 |
2023-08-13 |
Not clear |
Xi Xiao, Xinxin Xu, Fangjuan Li, Guomin Xie, Tao Zhan. Anti-inflammatory treatment with β-asarone improves impairments in social interaction and cognition in MK-801 treated mice. Brain research bulletin. vol 150. 2020-07-24. PMID:31129169. |
extracellular field excitatory postsynaptic potentials were recorded in the hippocampal dentate gyrus (dg) region. |
2020-07-24 |
2023-08-13 |
mouse |
Xi Xiao, Xinxin Xu, Fangjuan Li, Guomin Xie, Tao Zhan. Anti-inflammatory treatment with β-asarone improves impairments in social interaction and cognition in MK-801 treated mice. Brain research bulletin. vol 150. 2020-07-24. PMID:31129169. |
immunofluorescence was performed to assess the microglial activation in the hippocampus dg region. |
2020-07-24 |
2023-08-13 |
mouse |
Julie Doan, Alain M Gardier, Laurent Tritschle. Role of adult-born granule cells in the hippocampal functions: Focus on the GluN2B-containing NMDA receptors. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 29. issue 10. 2020-07-14. PMID:31371103. |
adult-born granule cells constitute a small subpopulation of the dentate gyrus (dg) in the hippocampus. |
2020-07-14 |
2023-08-13 |
Not clear |
Julie Doan, Alain M Gardier, Laurent Tritschle. Role of adult-born granule cells in the hippocampal functions: Focus on the GluN2B-containing NMDA receptors. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 29. issue 10. 2020-07-14. PMID:31371103. |
their stimulation decreases the overall excitation/inhibition balance of the dg via recruitment of local interneurons, and in the ca3 region of the hippocampus. |
2020-07-14 |
2023-08-13 |
Not clear |
Tamar Licht, Tirzah Kreisel, Yoav Biala, Sandesh Mohan, Yoel Yaari, Andrey Anisimov, Kari Alitalo, Eli Keshe. Age-Dependent Remarkable Regenerative Potential of the Dentate Gyrus Provided by Intrinsic Stem Cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 5. 2020-07-09. PMID:31959697. |
here we focused on the hippocampus and especially the dentate gyrus (dg), a vulnerable brain region and one of the two sites where adult neuronal stem cells (nscs) reside. |
2020-07-09 |
2023-08-13 |
mouse |
Tamar Licht, Tirzah Kreisel, Yoav Biala, Sandesh Mohan, Yoel Yaari, Andrey Anisimov, Kari Alitalo, Eli Keshe. Age-Dependent Remarkable Regenerative Potential of the Dentate Gyrus Provided by Intrinsic Stem Cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 5. 2020-07-09. PMID:31959697. |
while adult hippocampal neurogenesis was extensively studied with regard to its contribution to cognitive enhancement, we focused on their underestimated capability to repair a massively injured, nonfunctional dg. |
2020-07-09 |
2023-08-13 |
mouse |
Tamar Licht, Tirzah Kreisel, Yoav Biala, Sandesh Mohan, Yoel Yaari, Andrey Anisimov, Kari Alitalo, Eli Keshe. Age-Dependent Remarkable Regenerative Potential of the Dentate Gyrus Provided by Intrinsic Stem Cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 5. 2020-07-09. PMID:31959697. |
the study thus revealed an unappreciated regenerative potential of the young dg and suggests hippocampal nscs as a critical reservoir enabling recovery from catastrophic dg damage. |
2020-07-09 |
2023-08-13 |
mouse |
Qiqi Song, Ya-Bo Feng, Liyan Wang, Jie Shen, Ye Li, Cuiqin Fan, Peng Wang, Shu Yan Y. COX-2 inhibition rescues depression-like behaviors via suppressing glial activation, oxidative stress and neuronal apoptosis in rats. Neuropharmacology. vol 160. 2020-07-08. PMID:31539536. |
cox-2 is highly expressed in the hippocampal dentate gyrus (dg) of rat depression model and its activity is responsible for depression-like behaviors as demonstrated in two independent rat models of depression. |
2020-07-08 |
2023-08-13 |
rat |
Bin Xu, Li-Min Lang, Shi-Ze Li, Jing-Ru Guo, Jian-Fa Wang, Huan-Min Yang, Shuai Lia. Microglia Activated by Excess Cortisol Induce HMGB1 Acetylation and Neuroinflammation in the Hippocampal DG Region of Mice Following Cold Exposure. Biomolecules. vol 9. issue 9. 2020-07-06. PMID:31480279. |
microglia activated by excess cortisol induce hmgb1 acetylation and neuroinflammation in the hippocampal dg region of mice following cold exposure. |
2020-07-06 |
2023-08-13 |
mouse |
Bin Xu, Li-Min Lang, Shi-Ze Li, Jing-Ru Guo, Jian-Fa Wang, Huan-Min Yang, Shuai Lia. Microglia Activated by Excess Cortisol Induce HMGB1 Acetylation and Neuroinflammation in the Hippocampal DG Region of Mice Following Cold Exposure. Biomolecules. vol 9. issue 9. 2020-07-06. PMID:31480279. |
cold stress can induce neuroinflammation in the hippocampal dentate gyrus (dg), but the mechanism underlying neuronal apoptosis induced by cold stress is not well-understood. |
2020-07-06 |
2023-08-13 |
mouse |
Farong Ou, Kai Su, Jiadong Sun, Zhiguang Zhang, Yun Peng, Guiqing Lia. Temporomandibular joint disorders contribute to anxiety in BalB/C mice. Biochemical and biophysical research communications. vol 516. issue 2. 2020-07-01. PMID:31208723. |
additionally, exposure to chronic restraint stress for 3 weeks after tmd significantly exacerbated anxiety-like behavior and resulted in a significant increase in serum corticosterone levels and in the expression of mbp and rip in the dentate gyrus (dg) and ca3 in the hippocampus. |
2020-07-01 |
2023-08-13 |
mouse |
Sadhna Rao, Yuni Kay, Bruce E Herrin. Tiam1 is Critical for Glutamatergic Synapse Structure and Function in the Hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 47. 2020-07-01. PMID:31597723. |
recent work has identified substantial divergence of molecular composition between commonly studied schaffer collateral synapses and perforant path-dentate gyrus (dg) synapses of the hippocampus. |
2020-07-01 |
2023-08-13 |
rat |
Yanina Mircheva, Modesto R Peralta, Katalin Tót. Interplay of Entorhinal Input and Local Inhibitory Network in the Hippocampus at the Origin of Slow Inhibition in Granule Cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 33. 2020-06-22. PMID:31182636. |
neuronal activity from the entorhinal cortex propagates through the perforant path (pp) to the molecular layer of the dentate gyrus (dg) where information is filtered and converted into sparse hippocampal code. |
2020-06-22 |
2023-08-13 |
Not clear |
Tae-Kyung Han, Yea-Hyun Leem, Hee-Sun Ki. Treadmill exercise restores high fat diet-induced disturbance of hippocampal neurogenesis through β2-adrenergic receptor-dependent induction of thioredoxin-1 and brain-derived neurotrophic factor. Brain research. vol 1707. 2020-06-11. PMID:30496734. |
the exercise inhibited hfd-induced microglial activation, expression of proinflammatory cytokines (tumor necrosis factor-α and interleukin-1β), and nf-κb activity in the dentate gyrus (dg) of the hippocampus. |
2020-06-11 |
2023-08-13 |
mouse |
Tae-Kyung Han, Yea-Hyun Leem, Hee-Sun Ki. Treadmill exercise restores high fat diet-induced disturbance of hippocampal neurogenesis through β2-adrenergic receptor-dependent induction of thioredoxin-1 and brain-derived neurotrophic factor. Brain research. vol 1707. 2020-06-11. PMID:30496734. |
in addition, the exercise reduced malondialdehyde levels elevated by hfd and recovered antioxidant superoxide dismutase and glutathione levels in hippocampal dg of hfd-mice. |
2020-06-11 |
2023-08-13 |
mouse |
Tae-Kyung Han, Yea-Hyun Leem, Hee-Sun Ki. Treadmill exercise restores high fat diet-induced disturbance of hippocampal neurogenesis through β2-adrenergic receptor-dependent induction of thioredoxin-1 and brain-derived neurotrophic factor. Brain research. vol 1707. 2020-06-11. PMID:30496734. |
therefore, our data collectively suggests that regular exercise may be a promising approach to preventing hfd-induced memory impairments via anti-inflammatory, antioxidant and neuroprotective mechanisms in the hippocampal dg region. |
2020-06-11 |
2023-08-13 |
mouse |
Luis J Quintanilla, Chia-Yu Yeh, Hechen Bao, Christina Catavero, Juan Son. Assaying Circuit Specific Regulation of Adult Hippocampal Neural Precursor Cells. Journal of visualized experiments : JoVE. issue 149. 2020-06-10. PMID:31403615. |
adult neurogenesis is a dynamic process by which newly activated neural stem cells (nscs) in the subgranular zone (sgz) of the dentate gyrus (dg) generate new neurons, which integrate into an existing neural circuit and contribute to specific hippocampal functions. |
2020-06-10 |
2023-08-13 |
Not clear |