| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| b' M Maccarrone, A Finazzi-Agr\\xc3\\xb. The endocannabinoid system, anandamide and the regulation of mammalian cell apoptosis. Cell death and differentiation. vol 10. issue 9. 2004-04-16. PMID:12934069.' |
anandamide (n-arachidonoylethanolamine; aea) and 2-arachidonoylglycerol (2-ag) are the main endogenous agonists of cannabinoid receptors able to mimic several pharmacological effects of delta-9-tetrahydrocannabinol, the active principle of cannabis sativa preparations like hashish and marijuana. |
2004-04-16 |
2023-08-12 |
Not clear |
| Aquiles J Roncoron. [Medical use of cannabis and synthetic cannabinoids]. Medicina. vol 63. issue 6. 2004-04-09. PMID:14719320. |
[medical use of cannabis and synthetic cannabinoids]. |
2004-04-09 |
2023-08-12 |
Not clear |
| Giovanni Diana, Massimiliano Malloni, Massimo Pier. Effects of the synthetic cannabinoid nabilone on spatial learning and hippocampal neurotransmission. Pharmacology, biochemistry, and behavior. vol 75. issue 3. 2004-04-08. PMID:12895676. |
cannabinoids, the active components of marijuana, affect memory and hippocampal neurotransmission. |
2004-04-08 |
2023-08-12 |
rat |
| Stefan Hart, Oliver M Fischer, Axel Ullric. Cannabinoids induce cancer cell proliferation via tumor necrosis factor alpha-converting enzyme (TACE/ADAM17)-mediated transactivation of the epidermal growth factor receptor. Cancer research. vol 64. issue 6. 2004-04-08. PMID:15026328. |
cannabinoids, the active components of marijuana and their endogenous counterparts were reported as useful analgetic agents to accompany primary cancer treatment by preventing nausea, vomiting, and pain and by stimulating appetite. |
2004-04-08 |
2023-08-12 |
Not clear |
| Paola Massi, Angelo Vaccani, Stefania Ceruti, Arianna Colombo, Maria P Abbracchio, Daniela Parolar. Antitumor effects of cannabidiol, a nonpsychoactive cannabinoid, on human glioma cell lines. The Journal of pharmacology and experimental therapeutics. vol 308. issue 3. 2004-04-06. PMID:14617682. |
antitumor effects of cannabidiol, a nonpsychoactive cannabinoid, on human glioma cell lines. |
2004-04-06 |
2023-08-12 |
mouse |
| Paola Massi, Angelo Vaccani, Stefania Ceruti, Arianna Colombo, Maria P Abbracchio, Daniela Parolar. Antitumor effects of cannabidiol, a nonpsychoactive cannabinoid, on human glioma cell lines. The Journal of pharmacology and experimental therapeutics. vol 308. issue 3. 2004-04-06. PMID:14617682. |
because the psychoactivity of cannabinoid compounds limits their medicinal usage, we undertook the present study to evaluate the in vitro antiproliferative ability of cannabidiol (cbd), a nonpsychoactive cannabinoid compound, on u87 and u373 human glioma cell lines. |
2004-04-06 |
2023-08-12 |
mouse |
| Gisela Skopp, Barbara Richter, Lucia Pötsc. [Serum cannabinoid levels 24 to 48 hours after cannabis smoking]. Archiv fur Kriminologie. vol 212. issue 3-4. 2004-03-29. PMID:14639811. |
[serum cannabinoid levels 24 to 48 hours after cannabis smoking]. |
2004-03-29 |
2023-08-12 |
Not clear |
| Jana Thorspecken, Gisela Skopp, Lucia Pötsc. In vitro contamination of hair by marijuana smoke. Clinical chemistry. vol 50. issue 3. 2004-03-24. PMID:14726468. |
we studied external uptake of cannabinoids from marijuana smoke, investigating possible influencing factors on drug uptake and the efficiency of decontamination procedures. |
2004-03-24 |
2023-08-12 |
Not clear |
| Robert B Zurie. Prospects for cannabinoids as anti-inflammatory agents. Journal of cellular biochemistry. vol 88. issue 3. 2004-03-23. PMID:12532323. |
it is likely that the therapeutic benefits of smoked marijuana are due to some combination of its more than 60 cannabinoids and 200-250 non-cannabinoid constituents. |
2004-03-23 |
2023-08-12 |
Not clear |
| Robert B Zurie. Prospects for cannabinoids as anti-inflammatory agents. Journal of cellular biochemistry. vol 88. issue 3. 2004-03-23. PMID:12532323. |
understanding the mechanisms of the therapeutic effects of nonpsychoactive cannabinoids should lead to development of safe effective treatment for several diseases, and may render moot the debate about "medical marijuana". |
2004-03-23 |
2023-08-12 |
Not clear |
| Andrew J Irving, Mark G Rae, Angela A Coutt. Cannabinoids on the brain. TheScientificWorldJournal. vol 2. 2004-03-23. PMID:12805989. |
recently there have been significant advances in our understanding of how cannabis and related compounds (cannabinoids) affect the brain and this review addresses the current state of knowledge of these effects. |
2004-03-23 |
2023-08-12 |
Not clear |
| Thomas W Klein, Cathy Newton, Kellie Larsen, Joe Chou, Izabella Perkins, Lily Lu, Liang Nong, Herman Friedma. Cannabinoid receptors and T helper cells. Journal of neuroimmunology. vol 147. issue 1-2. 2004-03-15. PMID:14741435. |
we have reported that injection of marijuana cannabinoids, such as delta(9)-tetrahydrocannabinol (thc), into mice, followed by infection with legionella pneumophila (lp), suppresses the development of cell-mediated immunity t helper 1 (th1) activity. |
2004-03-15 |
2023-08-12 |
mouse |
| Franjo Grotenhermen, Kirsten Müller-Vah. IACM 2nd Conference on Cannabinoids in Medicine. Expert opinion on pharmacotherapy. vol 4. issue 12. 2004-03-12. PMID:14640935. |
the international association for cannabis as medicine 2nd conference on cannabinoids in medicine focused on new clinical research with cannabis and single cannabinoids (delta(9)-tetrahydrocannabinol, ct-3) and on animal research with possible therapeutic implications. |
2004-03-12 |
2023-08-12 |
Not clear |
| Attila Losonczy, Agota A Biró, Zoltan Nusse. Persistently active cannabinoid receptors mute a subpopulation of hippocampal interneurons. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 5. 2004-03-09. PMID:14734812. |
here, we report that persistently active cannabinoid receptors, the site of action of endocannabinoids, and the psychostimulants marijuana and hashish, switch off the output (mute) of a unique class of hippocampal ins. |
2004-03-09 |
2023-08-12 |
Not clear |
| Margaret Haney, Carl L Hart, Suzanne K Vosburg, Jennifer Nasser, Andrew Bennett, Carlos Zubaran, Richard W Folti. Marijuana withdrawal in humans: effects of oral THC or divalproex. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 1. 2004-02-17. PMID:14560320. |
two placebo-controlled, within-subject studies investigated the effects of a cannabinoid agonist, delta-9-tetrahydrocannabinol (thc: study 1), and a mood stabilizer, divalproex (study 2), on symptoms of marijuana withdrawal. |
2004-02-17 |
2023-08-12 |
human |
| David Robbe, Gerard Alonso, Oliver J Manzon. Exogenous and endogenous cannabinoids control synaptic transmission in mice nucleus accumbens. Annals of the New York Academy of Sciences. vol 1003. 2004-02-13. PMID:14684448. |
the fact that this new form of ltd was occluded by an exogenous cannabinoid suggested that cannabis derivatives, such as marijuana, may alter normal ecb-mediated synaptic plasticity. |
2004-02-13 |
2023-08-12 |
mouse |
| Zuzana Justinova, Gianluigi Tanda, Godfrey H Redhi, Steven R Goldber. Self-administration of delta9-tetrahydrocannabinol (THC) by drug naive squirrel monkeys. Psychopharmacology. vol 169. issue 2. 2004-02-10. PMID:12827345. |
interest in therapeutic activities of cannabinoids has been restrained by the fact that they are most often mediated through activation of cannabinoid cb1 receptors, the same receptors that mediate the effects of delta9-tetrahydrocannabinol (thc) and are responsible for the abuse liability of marijuana. |
2004-02-10 |
2023-08-12 |
monkey |
| Alison J Drysdale, Bettina Plat. Cannabinoids: mechanisms and therapeutic applications in the CNS. Current medicinal chemistry. vol 10. issue 24. 2004-02-02. PMID:14529462. |
cannabinoids comprise three classes of compounds, the active components of marijuana (cannabis sativa), as well as endogenous and synthetic derivatives. |
2004-02-02 |
2023-08-12 |
Not clear |
| Malcolm Begg, Fong-Ming Mo, László Offertaler, Sándor Bátkai, Pál Pacher, Raj K Razdan, David M Lovinger, George Kuno. G protein-coupled endothelial receptor for atypical cannabinoid ligands modulates a Ca2+-dependent K+ current. The Journal of biological chemistry. vol 278. issue 46. 2003-12-24. PMID:12952947. |
the cannabinoid analog "abnormal cannabidiol" (abn-cbd) causes endothelium-dependent vasodilation in rat isolated mesenteric arteries through a g protein-coupled receptor distinct from cb1 or cb2. |
2003-12-24 |
2023-08-12 |
human |
| Kirsten R Müller-Vah. Cannabinoids reduce symptoms of Tourette's syndrome. Expert opinion on pharmacotherapy. vol 4. issue 10. 2003-12-18. PMID:14521482. |
at present, it remains unclear whether herbal cannabis, different natural or synthetic cannabinoid cb1-receptor agonists or agents that interfere with the inactivation of endocannabinoids, may have the best adverse effect profile in ts. |
2003-12-18 |
2023-08-12 |
Not clear |