| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A de Bartolomeis, M C Austin, G A Goodwin, L P Spear, D Pickar, J N Crawle. Dopaminergic and peptidergic mRNA levels in juvenile rat brain after prenatal cocaine treatment. Brain research. Molecular brain research. vol 21. issue 3-4. 1994-06-01. PMID:7909578. |
levels of mrna for the dopamine transporter, tyrosine hydroxylase, cholecystokinin, d1 and d2 dopamine receptors and enkephalin were quantitated in relevant dopaminergic regions of forebrain and midbrain of offspring that were sacrificed on postnatal day 21. |
1994-06-01 |
2023-08-12 |
rat |
| A J Lanç. Reduction of voluntary alcohol intake in the rat by modulation of the dopaminergic mesolimbic system: transplantation of ventral mesencephalic cell suspensions. Neuroscience. vol 58. issue 2. 1994-05-11. PMID:8152544. |
fetal dopaminergic transplants from ventral mesencephalon--but not dopamine-poor transplants or sham-operated animals--reduced the voluntary intake of ethanol by about 40-50%. |
1994-05-11 |
2023-08-12 |
rat |
| J Meek, H W Jooste. Tyrosine hydroxylase-immunoreactive cell groups in the brain of the teleost fish Gnathonemus petersii. Journal of chemical neuroanatomy. vol 6. issue 6. 1994-05-05. PMID:7908204. |
however, th-immunoreactive neurons in the midbrain tegmentum were not observed, confirming previous conclusions that a major difference between teleosts and mammals concerns the absence of dopaminergic midbrain groups and correlated mesencephalo-telencephalic projections in teleosts. |
1994-05-05 |
2023-08-12 |
Not clear |
| M A Hynes, K Poulsen, M Armanini, L Berkemeier, H Phillips, A Rosentha. Neurotrophin-4/5 is a survival factor for embryonic midbrain dopaminergic neurons in enriched cultures. Journal of neuroscience research. vol 37. issue 1. 1994-05-04. PMID:7908342. |
neurotrophin-4/5 is a survival factor for embryonic midbrain dopaminergic neurons in enriched cultures. |
1994-05-04 |
2023-08-12 |
rat |
| M A Hynes, K Poulsen, M Armanini, L Berkemeier, H Phillips, A Rosentha. Neurotrophin-4/5 is a survival factor for embryonic midbrain dopaminergic neurons in enriched cultures. Journal of neuroscience research. vol 37. issue 1. 1994-05-04. PMID:7908342. |
thus, nt-4/5 could be a physiological survival factor for midbrain dopaminergic neurons and may be useful as a therapeutic agent for parkinson's disease. |
1994-05-04 |
2023-08-12 |
rat |
| P Ernfors, K F Lee, R Jaenisc. Mice lacking brain-derived neurotrophic factor develop with sensory deficits. Nature. vol 368. issue 6467. 1994-04-28. PMID:8139657. |
it also prevents the death of motor neurons and midbrain dopaminergic neurons induced by lesions. |
1994-04-28 |
2023-08-12 |
mouse |
| P Ernfors, K F Lee, R Jaenisc. Mice lacking brain-derived neurotrophic factor develop with sensory deficits. Nature. vol 368. issue 6467. 1994-04-28. PMID:8139657. |
survival of sympathetic, midbrain dopaminergic and motor neurons is not affected. |
1994-04-28 |
2023-08-12 |
mouse |
| K Komori, M Nakamura, H Yamaoka, Y Kunimi, K Yamaoka, K Fujita, H Naitoh, N Karasawa, M Kuroda, T It. [Evidence for the existence of L-dopa-immunoreactive neurons in the human mesencephalic region]. No to shinkei = Brain and nerve. vol 46. issue 1. 1994-04-26. PMID:8136201. |
on the other hand, we observed a few l-dopa-positive/da-negative cell bodies in the dopaminergic regions in the midbrain. |
1994-04-26 |
2023-08-12 |
human |
| E Koutsilieri, W W Chan, D Reinitzer, W D Rausc. Functional changes in cocultures of mesencephalon and striatal neurons from embryonic C57/BL6 mice due to low concentrations of 1-methyl-4-phenylpyridinium (MPP+). Journal of neural transmission. General section. vol 94. issue 3. 1994-04-12. PMID:7907217. |
cocultures from ventral mesencephalon and neostriatum of embryonic c57/bl6 mouse brains were used to study the sensitivity of dopaminergic neurons to the toxic agent mpp+. |
1994-04-12 |
2023-08-12 |
mouse |
| J Wang, K S Bankiewicz, R J Plunkett, E H Oldfiel. Intrastriatal implantation of interleukin-1. Reduction of parkinsonism in rats by enhancing neuronal sprouting from residual dopaminergic neurons in the ventral tegmental area of the midbrain. Journal of neurosurgery. vol 80. issue 3. 1994-03-30. PMID:7906726. |
reduction of parkinsonism in rats by enhancing neuronal sprouting from residual dopaminergic neurons in the ventral tegmental area of the midbrain. |
1994-03-30 |
2023-08-12 |
rat |
| J Wang, K S Bankiewicz, R J Plunkett, E H Oldfiel. Intrastriatal implantation of interleukin-1. Reduction of parkinsonism in rats by enhancing neuronal sprouting from residual dopaminergic neurons in the ventral tegmental area of the midbrain. Journal of neurosurgery. vol 80. issue 3. 1994-03-30. PMID:7906726. |
because in these animals, especially in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned monkeys, there are still considerable numbers of dopaminergic neurons left in the mesencephalon, implantation-induced trophic effects on host residual dopaminergic neurons have been suggested as a mechanism underlying the behavioral recovery. |
1994-03-30 |
2023-08-12 |
rat |
| J Villares, B Faucheux, O Strada, E C Hirsch, Y Agid, F Javoy-Agi. Autoradiographic study of [125I]epidermal growth factor-binding sites in the mesencephalon of control and parkinsonian brains post-mortem. Brain research. vol 628. issue 1-2. 1994-03-23. PMID:8313172. |
an autoradiographic study of the distribution of egf-binding sites was performed in the mesencephalon of controls and patients with parkinson's disease, a neurodegenerative disease associated with dramatic damage to the mesostriatal dopaminergic neurons. |
1994-03-23 |
2023-08-12 |
Not clear |
| J Villares, B Faucheux, O Strada, E C Hirsch, Y Agid, F Javoy-Agi. Autoradiographic study of [125I]epidermal growth factor-binding sites in the mesencephalon of control and parkinsonian brains post-mortem. Brain research. vol 628. issue 1-2. 1994-03-23. PMID:8313172. |
this suggests that egf receptors in the mesencephalon are unaffected in parkinson's disease and may therefore contribute to the increased activity and survival of the remaining dopaminergic neurons. |
1994-03-23 |
2023-08-12 |
Not clear |
| J S Purba, M A Hofman, D F Swaa. Decreased number of oxytocin-immunoreactive neurons in the paraventricular nucleus of the hypothalamus in Parkinson's disease. Neurology. vol 44. issue 1. 1994-02-22. PMID:7904735. |
the presence of tyrosine hydroxylase-positive neurons in the pvn was not affected in pd patients, supporting the notion that dopaminergic neurons of the mesencephalon, but not of the hypothalamus, are affected in pd. |
1994-02-22 |
2023-08-12 |
human |
| K B Seroogy, C M Gal. Expression of neurotrophins by midbrain dopaminergic neurons. Experimental neurology. vol 124. issue 1. 1994-02-16. PMID:8282069. |
expression of neurotrophins by midbrain dopaminergic neurons. |
1994-02-16 |
2023-08-12 |
Not clear |
| C Hyman, M Juhasz, C Jackson, P Wright, N Y Ip, R M Lindsa. Overlapping and distinct actions of the neurotrophins BDNF, NT-3, and NT-4/5 on cultured dopaminergic and GABAergic neurons of the ventral mesencephalon. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 1. 1994-02-16. PMID:8283241. |
overlapping and distinct actions of the neurotrophins bdnf, nt-3, and nt-4/5 on cultured dopaminergic and gabaergic neurons of the ventral mesencephalon. |
1994-02-16 |
2023-08-12 |
rat |
| C Hyman, M Juhasz, C Jackson, P Wright, N Y Ip, R M Lindsa. Overlapping and distinct actions of the neurotrophins BDNF, NT-3, and NT-4/5 on cultured dopaminergic and GABAergic neurons of the ventral mesencephalon. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 1. 1994-02-16. PMID:8283241. |
the neurotrophins brain-derived neurotrophic factor (bdnf), neurotrophin-3 (nt-3), and neurotrophin-4/5 (nt-4/5) were compared for their effects in promoting the survival and/or regulation of expression of phenotypic markers of dopaminergic and gabaergic neurons in cultures derived from embryonic rat ventral mesencephalon. |
1994-02-16 |
2023-08-12 |
rat |
| M T Herrero, I Perez-Otaño, C Oset, A Kastner, E C Hirsch, Y Agid, M R Luquin, J A Obeso, J Del Ri. GM-1 ganglioside promotes the recovery of surviving midbrain dopaminergic neurons in MPTP-treated monkeys. Neuroscience. vol 56. issue 4. 1994-02-14. PMID:7904332. |
gm-1 ganglioside promotes the recovery of surviving midbrain dopaminergic neurons in mptp-treated monkeys. |
1994-02-14 |
2023-08-12 |
monkey |
| M T Herrero, I Perez-Otaño, C Oset, A Kastner, E C Hirsch, Y Agid, M R Luquin, J A Obeso, J Del Ri. GM-1 ganglioside promotes the recovery of surviving midbrain dopaminergic neurons in MPTP-treated monkeys. Neuroscience. vol 56. issue 4. 1994-02-14. PMID:7904332. |
these results indicate that gm-1 does not protect against cell death but exerts a neurotrophic effect on surviving dopaminergic neurons in the midbrain of mptp-lesioned monkeys, suggesting that gm-1 ganglioside may be potentially useful for the treatment of neurodegenerative disorders such as parkinson's disease. |
1994-02-14 |
2023-08-12 |
monkey |
| N Rentero, K Kitahama, L Quinti. Baroreceptor reflex-linked changes in catechol metabolism in the rat rostral ventrolateral medulla. The Journal of physiology. vol 469. 1994-01-31. PMID:8271225. |
furthermore, controlled hypotension induced in intact rats did not evoke any change in the catechol signal recorded in a dopaminergic area of the midbrain, the ventral tegmental area (a10 area; n = 5). |
1994-01-31 |
2023-08-12 |
rat |