| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Van Hest, F van Haaren, N E van de Pol. Haloperidol, but not apomorphine, differentially affects low response rates of male and female Wistar rats. Pharmacology, biochemistry, and behavior. vol 29. issue 3. 1988-06-09. PMID:3362947. |
low doses of apomorphine act on the dopamine receptors on the dopaminergic terminals themselves to inhibit the release of endogenous dopamine. |
1988-06-09 |
2023-08-11 |
human |
| A Van Hest, F van Haaren, N E van de Pol. Haloperidol, but not apomorphine, differentially affects low response rates of male and female Wistar rats. Pharmacology, biochemistry, and behavior. vol 29. issue 3. 1988-06-09. PMID:3362947. |
a behavioral difference between the sexes was thus observed when post-synaptic dopamine receptors were blocked by a dopamine antagonist, but not when dopaminergic stimulation of post-synaptic dopamine receptors was reduced by pre-synaptic inhibition of dopamine release. |
1988-06-09 |
2023-08-11 |
human |
| A Imperato, G Tanda, R Frau, G Di Chiar. Pharmacological profile of dopamine receptor agonists as studied by brain dialysis in behaving rats. The Journal of pharmacology and experimental therapeutics. vol 245. issue 1. 1988-06-02. PMID:3258912. |
using the technique of brain dialysis in freely moving rats we have investigated the effect of various dopamine (da) receptor agonists on the release and metabolism of da in two terminal dopaminergic areas, the nucleus accumbens and the dorsal caudate. |
1988-06-02 |
2023-08-11 |
rat |
| H R Lin, G Van der Kraak, X J Zhou, J Y Liang, R E Peter, J E Rivier, W W Val. Effects of [D-Arg6, Trp7, Leu8, Pro9NEt]-luteinizing hormone-releasing hormone (sGnRH-A) and [D-Ala6, Pro9NEt]-luteinizing hormone-releasing hormone (LHRH-A), in combination with pimozide or domperidone, on gonadotropin release and ovulation in the Chinese loach and common carp. General and comparative endocrinology. vol 69. issue 1. 1988-06-02. PMID:3282976. |
the present studies suggest that there are marked differences in the relative contribution of gnrh and dopamine in the control of gth secretion in loach and common carp, and indicate in particular that the more intense dopaminergic inhibitory control of gth release in common carp modifies the responsiveness of the pituitary to gnrh peptides. |
1988-06-02 |
2023-08-11 |
Not clear |
| K Sasaki, H Suda, H Watanabe, S Kaneko, Y Nomura, H Nishino, T On. Habenular lesion attenuates methamphetamine-induced inhibition of dopamine neuronal activity in the substantia nigra pars compacta of rats. Neuroscience letters. vol 86. issue 1. 1988-06-02. PMID:3362431. |
the relation between the habenula and central dopaminergic system was investigated by examining the inhibitory effects of methamphetamine on the firing rate of dopamine neurons in the substantia nigra of habenular lesioned and unlesioned rats. |
1988-06-02 |
2023-08-11 |
rat |
| R N Day, P M Hinkl. Transient dopaminergic inhibition of prolactin release from hybrid cells derived by fusion of normal rat pituitary and GH4C1 tumor cells. Endocrinology. vol 122. issue 5. 1988-06-01. PMID:3129281. |
these results demonstrate that gh4c1 cells may have the genetic information necessary for dopaminergic inhibition of prl synthesis, but that the dopamine response is not observed under standard tissue culture conditions. |
1988-06-01 |
2023-08-11 |
rat |
| J R Sanchez-Ramos, G E Hollinden, T J Sick, M Rosentha. 1-Methyl-4-phenylpyridinium (MPP+) increases oxidation of cytochrome-b in rat striatal slices. Brain research. vol 443. issue 1-2. 1988-05-31. PMID:3258785. |
this effect of mpp+ was decreased by co-incubation with a potent dopamine uptake inhibitor (mazindol), or when studied in a tissue with low dopaminergic innervation (hippocampus). |
1988-05-31 |
2023-08-11 |
rat |
| W Mihatsch, H Russ, H Przunte. Intracerebroventricular administration of 1-methyl-4-phenylpyridinium ion in mice: effects of simultaneously administered nomifensine, deprenyl, and 1-t-butyl-4,4-diphenylpiperidine. Journal of neural transmission. vol 71. issue 3. 1988-05-26. PMID:3128644. |
mptp is oxidized by monoamine oxidase b (mao b) to the 1-methyl-4-phenylpyridinium ion (mpp+), which is taken up in dopaminergic neurons through the dopamine (da) uptake system, where it develops its toxic effect. |
1988-05-26 |
2023-08-11 |
mouse |
| P Angchanpen, M Marin-Grez, J Schnerman. Effect of dopamine antagonists on the urine flow of rats infused with hypotonic saline. British journal of pharmacology. vol 93. issue 1. 1988-04-28. PMID:2894873. |
these results suggest that dopamine antagonists blunted the hypotonic saline-induced diuresis by favouring adh release through an interference with an inhibitory dopaminergic pathway. |
1988-04-28 |
2023-08-11 |
rat |
| H N Bhargava, M J Perlo. Effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine on striatal dopamine receptors in C57BL/6 mice. Toxicology letters. vol 40. issue 3. 1988-04-25. PMID:3258448. |
the effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp), a neurotoxin which selectively destroys the nigrostriatal dopaminergic neurons and produces parkinson's disease-like syndrome, on striatal dopamine receptors was determined in a mouse strain known to be very sensitive to the neurotoxic effect of mptp. |
1988-04-25 |
2023-08-11 |
mouse |
| E Melame. Brain grafting may reverse loss of responsiveness to levodopa therapy in Parkinson's disease. Clinical neuropharmacology. vol 11. issue 1. 1988-04-25. PMID:3280129. |
this may be due in part to near-total degeneration of the surviving nigrostriatal dopaminergic neurons during disease progression, with massive decreases in the capacity of the striatum to form and store dopamine from exogenous levodopa. |
1988-04-25 |
2023-08-11 |
Not clear |
| M Da Prada, A M Cesura, J M Launay, J G Richard. Platelets as a model for neurones? Experientia. vol 44. issue 2. 1988-04-20. PMID:2831073. |
in addition, the affinity displayed by dopamine and by dopaminergic neurotoxin mpp+ for the platelet 5-ht transport and storage indicates also some similarities between platelets and the dopaminergic system of the cns. |
1988-04-20 |
2023-08-11 |
human |
| M B Youdi. Platelet monoamine oxidase B: use and misuse. Experientia. vol 44. issue 2. 1988-04-20. PMID:3278920. |
similar to the major form of mao in the human brain, this enzyme actively oxidizes a-b and b substrates (tyramine, dopamine, phenylethylamine) as well as the novel secondary amine anticonvulsant, milacemide and dopaminergic neurotoxin, mptp. |
1988-04-20 |
2023-08-11 |
human |
| L A Bero, S N Lurie, C M Kuh. Early ontogeny of kappa-opioid receptor regulation of prolactin secretion in the rat. Brain research. vol 465. issue 1-2. 1988-04-19. PMID:2894234. |
kappa-receptors appear to regulate prl secretion by directly inhibiting the activity of tuberoinfundibular dopamine neurons, while mu-receptors might regulate the tonic dopaminergic inhibition of prl through a serotonergic pathway. |
1988-04-19 |
2023-08-11 |
rat |
| G A Gudelsky, J I Koenig, T Koyama, H Y Meltze. Activity of tuberoinfundibular dopaminergic neurons and concentrations of serum prolactin in the rat following lithium administration. Psychopharmacology. vol 94. issue 1. 1988-04-18. PMID:3126532. |
lithium treatment also resulted in an increase in the activity of tuberoinfundibular dopaminergic neurons, as evidenced by an increased accumulation of dihydroxyphenylalanine (dopa) in the median eminence after inhibition of dopa decarboxylase and an increased concentration of dopamine in the anterior pituitary gland. |
1988-04-18 |
2023-08-11 |
rat |
| G A Gudelsky, J I Koenig, T Koyama, H Y Meltze. Activity of tuberoinfundibular dopaminergic neurons and concentrations of serum prolactin in the rat following lithium administration. Psychopharmacology. vol 94. issue 1. 1988-04-18. PMID:3126532. |
it is concluded that lithium treatment enhances the synthesis of dopamine in many brain regions and that an increased activity of tuberoinfundibular dopaminergic neurons results in an enhanced inhibitory control of prl secretion. |
1988-04-18 |
2023-08-11 |
rat |
| R Dal Toso, O Giorgi, C Soranzo, G Kirschner, G Ferrari, M Favaron, D Benvegnù, D Presti, S Vicini, G Toffan. Development and survival of neurons in dissociated fetal mesencephalic serum-free cell cultures: I. Effects of cell density and of an adult mammalian striatal-derived neuronotrophic factor (SDNF). The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 8. issue 3. 1988-04-14. PMID:3346717. |
results indicate that the increase of cell density in vitro significantly enhances specific high-affinity dopamine uptake per dopaminergic cell and cell survival. |
1988-04-14 |
2023-08-11 |
mouse |
| E Y Eaker, G B Bixler, A J Dunn, W V Moreshead, J R Mathia. Dopamine and norepinephrine in the gastrointestinal tract of mice and the effects of neurotoxins. The Journal of pharmacology and experimental therapeutics. vol 244. issue 2. 1988-04-12. PMID:3126292. |
the relative percentage of dopamine to norepinephrine in noradrenergically innervated tissues (e.g., spleen) is known to be relatively constant within a species, and an increased percentage in any given tissue supports the premise that dopaminergic cells are present. |
1988-04-12 |
2023-08-11 |
mouse |
| H Criswell, R A Mueller, G R Brees. Assessment of purine-dopamine interactions in 6-hydroxydopamine-lesioned rats: evidence for pre- and postsynaptic influences by adenosine. The Journal of pharmacology and experimental therapeutics. vol 244. issue 2. 1988-04-12. PMID:3126293. |
neonatal lesioning of dopaminergic neurons with 6-hydroxydopamine (6-ohda) has been proposed as a rodent model of the dopamine deficiency in this childhood disorder. |
1988-04-12 |
2023-08-11 |
rat |
| H Criswell, R A Mueller, G R Brees. Assessment of purine-dopamine interactions in 6-hydroxydopamine-lesioned rats: evidence for pre- and postsynaptic influences by adenosine. The Journal of pharmacology and experimental therapeutics. vol 244. issue 2. 1988-04-12. PMID:3126293. |
even though dopamine levels were decreased by at least 92%, both neonatal- and adult-6-ohda-lesioned rats had normal hypoxanthine-guanine phosphoribosyltransferase function and purine nucleotide levels (adenosine, adp, atp and amp), indicating that hypoxanthine-guanine phosphoribosyltransferase is not localized only to dopaminergic neurons in striatum. |
1988-04-12 |
2023-08-11 |
rat |