| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Selmanoff, R C Walovitch, G E Walker, E D Londo. Effects of hyperprolactinemia on plasma prolactin and glucose and on local cerebral glucose utilization. Journal of neurochemistry. vol 48. issue 1. 1987-01-29. PMID:3491876. |
elevated blood levels of prolactin increase the synthesis, turnover, and release of 3,4-dihydroxyphenylethylamine (dopamine) from the tuberoinfundibular dopaminergic neurons, which project to the median eminence. |
1987-01-29 |
2023-08-11 |
rat |
| M L Vargas, J A Martinez, M V Milané. Pharmacological evidence for the existence of interactions between dopaminergic and opioid peptidergic systems in guinea-pig ileum myenteric plexus. European journal of pharmacology. vol 128. issue 3. 1987-01-27. PMID:3024995. |
these findings would indicate that the interruption of dopaminergic transmission in the myenteric plexus produces an increase in the release of opioid peptides and suggest an inhibitory modulation of opioid peptidergic neurons by dopamine systems at this level. |
1987-01-27 |
2023-08-11 |
Not clear |
| C F Saller, A I Salam. 3-Methoxytyramine accumulation: effects of typical neuroleptics and various atypical compounds. Naunyn-Schmiedeberg's archives of pharmacology. vol 334. issue 2. 1987-01-15. PMID:2878374. |
the accumulation of 3-methoxytyramine (3-mt), the o-methylated metabolite of dopamine (da), in rat striatum was used to assess the effects of drugs on dopaminergic activity. |
1987-01-15 |
2023-08-11 |
rat |
| M A Riddle, J F Leckman, D J Cohen, M Anderson, S I Ort, K A Caruso, B A Shaywit. Assessment of central dopaminergic function using plasma-free homovanillic acid after debrisoquin administration. Journal of neural transmission. vol 67. issue 1-2. 1987-01-15. PMID:3465864. |
central dopaminergic (da) function in children and adults was assessed by monitoring plasma-free levels of the dopamine metabolite homovanillic acid (phva) before and after a single oral dose and chronic oral administration of debrisoquin. |
1987-01-15 |
2023-08-11 |
human |
| M Andrejak, L Har. Enhanced dopamine renal responsiveness in patients with hypertension. Clinical pharmacology and therapeutics. vol 40. issue 6. 1987-01-14. PMID:3780122. |
the purpose of the study was to compare the renal effects of low doses of exogenous dopamine to assess the responsiveness of renal dopaminergic receptors in normotensive and hypertensive subjects. |
1987-01-14 |
2023-08-11 |
human |
| M Andrejak, L Har. Enhanced dopamine renal responsiveness in patients with hypertension. Clinical pharmacology and therapeutics. vol 40. issue 6. 1987-01-14. PMID:3780122. |
this enhanced response to exogenous dopamine can be considered as a further argument favoring the existence of a deficit in dopaminergic activity during hypertension. |
1987-01-14 |
2023-08-11 |
human |
| J Knol. [Medicamentous strategy for improving the quality of life in the senescence]. Wiener medizinische Wochenschrift. Supplement. vol 98. 1987-01-05. PMID:3097965. |
the striatum, in which the nigrostriatal dopaminergic neurons terminate, contains the highest amount of dopamine da) in the brain. |
1987-01-05 |
2023-08-11 |
human |
| M Steinhausen, S Weis, J Fleming, R Dussel, N Parek. Responses of in vivo renal microvessels to dopamine. Kidney international. vol 30. issue 3. 1986-12-31. PMID:3023735. |
these data indicate that the dilator effect of dopamine is mediated by interactions with specific dopaminergic receptors, while alpha and beta adrenergic receptors appear to mediate a constrictor influence observed with high dopamine concentrations. |
1986-12-31 |
2023-08-11 |
Not clear |
| L Zichella, P Falaschi, P Fioretti, G B Melis, A Cagnacci, M Gambacciani, S Mancin. Effects of different dopamine agonists and antagonists on post-menopausal hot flushes. Maturitas. vol 8. issue 3. 1986-12-31. PMID:3784919. |
a direct dopaminergic action is hypothesized in the case of bromocriptine and liposom, while the antidopaminergic drugs might act through different indirect mechanisms such as the short-loop feedback exerted by hyperprolactinaemia on tuberoinfundibular dopamine (tida) neurons with a secondary dopamine-like activity, or stimulation of the opioid system. |
1986-12-31 |
2023-08-11 |
Not clear |
| H S Kim, S Iyengar, P L Woo. Opiate actions on mesocortical dopamine metabolism in the rat. Life sciences. vol 39. issue 21. 1986-12-24. PMID:3784768. |
the actions of parenteral morphine were examined with regard to dopamine metabolism in the mesocortical dopaminergic pathways of the rat. |
1986-12-24 |
2023-08-11 |
rat |
| M Traub, A Reches, H R Wagner, S Fah. Reserpine-induced up-regulation of dopamine D2 receptors in the rat striatum is enhanced by denervation but not by chronic receptor blockade. Neuroscience letters. vol 70. issue 2. 1986-12-18. PMID:2946007. |
compensatory increases in the density of dopamine (da) d2 receptors in the rat striatum occur following chronic interruption of dopaminergic neurotransmission. |
1986-12-18 |
2023-08-11 |
rat |
| T L Perry, V W Yong, K Jones, J M Wrigh. Manipulation of glutathione contents fails to alter dopaminergic nigrostriatal neurotoxicity of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the mouse. Neuroscience letters. vol 70. issue 2. 1986-12-18. PMID:3490637. |
yet neither substance protected mice from the toxic effects of n-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) on dopaminergic nigrostriatal neurons, as shown by marked depletion of striatal dopamine content when animals were sacrificed. |
1986-12-18 |
2023-08-11 |
mouse |
| W C Koller, J Z Fields, J H Gordon, M J Perlo. Evaluation of ciladopa hydrochloride as a potential anti-Parkinson drug. Neuropharmacology. vol 25. issue 9. 1986-12-12. PMID:3774130. |
the effects of the putative dopamine agonist, ciladopa hydrochloride (ay 27,110) a non-ergot compound, were investigated in animal models of dopaminergic activity to evaluate its possible role in the treatment of parkinson's disease. |
1986-12-12 |
2023-08-11 |
rat |
| W C Koller, J Z Fields, J H Gordon, M J Perlo. Evaluation of ciladopa hydrochloride as a potential anti-Parkinson drug. Neuropharmacology. vol 25. issue 9. 1986-12-12. PMID:3774130. |
these data indicate that ciladopa can cause stimulation of central dopaminergic receptors and that the drug is a partial dopamine agonist with direct-acting properties. |
1986-12-12 |
2023-08-11 |
rat |
| P Carnoy, S Ravard, B Wemerman, P Soubrie, P Simo. Behavioral deficits induced by low doses of apomorphine in rats: evidence for a motivational and cognitive dysfunction which discriminates among neuroleptic drugs. Pharmacology, biochemistry, and behavior. vol 25. issue 3. 1986-12-10. PMID:2877466. |
in order to further assess the alterations (motor, motivational or cognitive) that might underlie animal behavioral deficits associated with a reduced dopamine transmission, the effects of apomorphine at doses thought to stimulate dopaminergic autoreceptors were studied on rat operant behavior. |
1986-12-10 |
2023-08-11 |
rat |
| P Chiodera, R Volpi, R Delsignore, C Marchesi, G Salati, L Camellini, G Rossi, V Coir. Different effects of metoclopramide and domperidone on arginine-vasopressin secretion in man. British journal of clinical pharmacology. vol 22. issue 4. 1986-12-10. PMID:3768259. |
metoclopramide, a cerebral and peripheral antagonist of dopaminergic receptors, significantly stimulated avp secretion, whereas domperidone, a dopamine antagonist which does not cross the blood-brain barrier, was without effect. |
1986-12-10 |
2023-08-11 |
Not clear |
| b' F Ferr\\xc3\\xa. Dopamine-stimulated adenylate cyclase in human term placenta. Life sciences. vol 39. issue 20. 1986-12-08. PMID:3773646.' |
these data indicate that dopamine stimulates camp formation in human term placenta through a specific mechanism via d1 dopaminergic receptors positively coupled to adenylate cyclase. |
1986-12-08 |
2023-08-11 |
human |
| T Bradley, A Sollevi, M Lagerkranse. Effect of hypotension induced by sodium nitroprusside on catecholamine overflow in the canine kidney. Acta physiologica Scandinavica. vol 128. issue 2. 1986-12-05. PMID:3776649. |
the overflow of noradrenaline (na) and dopamine (da) to plasma in the kidney in response to hypotension induced by sodium nitroprusside were studied in barbiturate-anaesthetized dogs in order to evaluate the possible existence of separately regulated renal noradrenergic and dopaminergic nerve fibres. |
1986-12-05 |
2023-08-11 |
Not clear |
| R L Stephens, N J Uretsk. Folate induced-hypermotility response after bilateral injection into the nucleus accumbens of the rat. Possible mediation through dopaminergic mechanisms. Neuropharmacology. vol 25. issue 8. 1986-11-24. PMID:3022181. |
these results suggest that folic acid and fthf produce an increase in locomotor activity by facilitating dopaminergic neurotransmission in the nucleus accumbens, possibly by inducing the release of dopamine from the nerve terminals. |
1986-11-24 |
2023-08-11 |
rat |
| I Strömberg, H Björklund, D Dahl, G Jonsson, E Sundström, L Olso. Astrocyte responses to dopaminergic denervations by 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine as evidenced by glial fibrillary acidic protein immunohistochemistry. Brain research bulletin. vol 17. issue 2. 1986-11-24. PMID:3094835. |
astrocytic responses to dopaminergic denervation by two widely used dopamine neurotoxins, 6-hydroxydopamine (6-ohda) and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) were monitored using immunofluorescence with antibodies against glial fibrillary acidic protein (gfa) while neurofilament (nf) antibodies were used to monitor neuronal disturbances. |
1986-11-24 |
2023-08-11 |
mouse |