| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P A Sullivan, V De Quattro, A Foti, G Curzo. Effects of clonidine on central and peripheral nerve tone in primary hypertension. Hypertension (Dallas, Tex. : 1979). vol 8. issue 7. 1986-07-30. PMID:3721561. |
the dopaminergic activity of cerebrospinal fluid was unaffected by clonidine, and though plasma dopamine levels tended to be lower after treatment, mean plasma prolactin level, an index of dopaminergic activity, was also unchanged. |
1986-07-30 |
2023-08-11 |
human |
| J Arita, F Kimur. Adenosine 3',5'-cyclic monophosphate stimulates dopamine biosynthesis in the median eminence of rat hypothalamic slices. Brain research. vol 374. issue 1. 1986-07-29. PMID:2424558. |
the regulation of dopamine biosynthesis in tuberoinfundibular dopaminergic (tida) neurons by adenosine 3',5'-cyclic monophosphate (camp) was investigated in the present study. |
1986-07-29 |
2023-08-11 |
rat |
| T Nishikawa, D Fage, B Scatto. Evidence for, and nature of, the tonic inhibitory influence of habenulointerpeduncular pathways upon cerebral dopaminergic transmission in the rat. Brain research. vol 373. issue 1-2. 1986-07-25. PMID:2424555. |
the potential role of the habenula in the transsynaptic regulation of the activity of ascending dopaminergic systems has been investigated in the rat by studying the effect of an acute interruption of impulse traffic in the diencephalic conduction system (stria medullaris-habenula-fasciculus retroflexus) and of pharmacological manipulation of various neurotransmitter systems in the interpeduncular nucleus on dopamine metabolism in several dopaminergic projection fields. |
1986-07-25 |
2023-08-11 |
rat |
| D P Worth, J N Harvey, J Brown, A Worral, M R Le. Domperidone treatment in man inhibits the fall in plasma renin activity induced by intravenous gamma-L-glutamyl-L-dopa. British journal of clinical pharmacology. vol 21. issue 5. 1986-07-25. PMID:3087398. |
these observations suggest that blockade of renal da2 dopamine receptors has little or no effect on gludopa-induced natriuresis, but that at least part of the dopaminergic inhibition of renin release is mediated by renal da2 receptors. |
1986-07-25 |
2023-08-11 |
human |
| J A Stamford, Z L Kruk, J Milla. In vivo voltammetric characterization of low affinity striatal dopamine uptake: drug inhibition profile and relation to dopaminergic innervation density. Brain research. vol 373. issue 1-2. 1986-07-25. PMID:3487373. |
in vivo voltammetric characterization of low affinity striatal dopamine uptake: drug inhibition profile and relation to dopaminergic innervation density. |
1986-07-25 |
2023-08-11 |
Not clear |
| M Ojima, N Itoh, Y Kusano, K Yaginuma, S Fukuch. [The effect of metoclopramide and dopamine on mineralocorticoid secretion--in vivo and in vitro studies]. Nihon Naibunpi Gakkai zasshi. vol 62. issue 3. 1986-07-24. PMID:3709883. |
the present studies were designed to investigate the mechanism of dopaminergic control of corticosteroid secretion and to determine at which step in the aldosterone biosynthetic pathway metoclopramide and dopamine exert their effect. |
1986-07-24 |
2023-08-11 |
human |
| N M White, J Blackbur. Effect of glucose on amphetamine-induced motor behavior. Life sciences. vol 38. issue 24. 1986-07-23. PMID:3086651. |
the findings are also consistent with other data suggesting that glucose antagonizes dopamine function, but they suggest that this antagonism may not be uniform over all dopaminergic neurons or receptor types. |
1986-07-23 |
2023-08-11 |
rat |
| C M Bitler, B D Howar. Dopamine metabolism in hypoxanthine-guanine phosphoribosyltransferase-deficient variants of PC12 cells. Journal of neurochemistry. vol 47. issue 1. 1986-07-23. PMID:3519867. |
to assess whether an hprt deficiency in a dopaminergic cell can adversely affect dopamine metabolism in that cell, dopamine metabolism was examined in hprt-deficient variants of pc12 pheochromocytoma cells and in cells that had regained hprt activity by virtue of transformation with a recombinant retrovirus containing the human gene for hprt. |
1986-07-23 |
2023-08-11 |
human |
| M A Sherman, D S Linthicum, M B Bolge. Haloperidol binding to monoclonal antibodies: conformational analysis and relationships to D-2 receptor binding. Molecular pharmacology. vol 29. issue 6. 1986-07-18. PMID:2423865. |
other dopaminergic ligands such as dopamine and the d-1 antagonist sch-23390 were not recognized by monoclonal antibodies raised against the succinic acid conjugate. |
1986-07-18 |
2023-08-11 |
mouse |
| N Tuross, R L Patric. Effects of propranolol on catecholamine synthesis and uptake in the central nervous system of the rat. The Journal of pharmacology and experimental therapeutics. vol 237. issue 3. 1986-07-16. PMID:2872325. |
these results indicate that propranolol administration may cause a potentiation of norepinephrine activity specifically at alpha receptors, due to concurrent beta receptor blockade and inhibition of norepinephrine reuptake and a decrease in dopamine activity at dopaminergic receptor sites due to an inhibition of dopamine formation. |
1986-07-16 |
2023-08-11 |
rat |
| L D Middaugh, J W Zem. Dopaminergic mediation of long-term behavioral effects of in utero drug exposure. Neurobehavioral toxicology and teratology. vol 7. issue 6. 1986-07-14. PMID:3835467. |
the dopaminergic systems are particularly suitable for examining the hypothesis, since the neural tracts using dopamine have been widely studied; their influence on behavior is, to some extent, understood; the tracts begin development in mice and rats late in gestation; and there are a number of drugs known to have particular effects on these systems. |
1986-07-14 |
2023-08-11 |
mouse |
| L D Middaugh, J W Zem. Dopaminergic mediation of long-term behavioral effects of in utero drug exposure. Neurobehavioral toxicology and teratology. vol 7. issue 6. 1986-07-14. PMID:3835467. |
literature is reviewed that supports the hypothesis that drugs affecting dopamine metabolism, when administered during the early development of the dopaminergic tracts, produce persistent changes both in the metabolism of dopamine and in behavior mediated by neural systems which utilize dopamine as a transmitter. |
1986-07-14 |
2023-08-11 |
mouse |
| L J Thal, K Laing, S G Horowitz, M H Makma. Dopamine stimulates rat cortical somatostatin release. Brain research. vol 372. issue 2. 1986-07-07. PMID:2871899. |
dopamine increased the release of somatostatin from cortex and this effect of dopamine was blocked by haloperidol and other dopaminergic antagonists. |
1986-07-07 |
2023-08-11 |
rat |
| G M Tyce, T L Yaks. Conjugates of biogenic amines in ventriculocisternal perfusates of conscious African green monkeys. Brain research. vol 372. issue 2. 1986-07-07. PMID:3708364. |
efflux of conjugated dopamine was not decreased in the presence of nomifensine, suggesting that conjugation did not occur subsequent to reuptake of transmitter into dopaminergic neurons. |
1986-07-07 |
2023-08-11 |
monkey |
| K Ando, C E Johanson, C R Schuste. Effects of dopaminergic agents on eye tracking before and after repeated methamphetamine. Pharmacology, biochemistry, and behavior. vol 24. issue 3. 1986-06-17. PMID:3703903. |
since other data reported elsewhere have shown that dopamine is depleted in the caudate after similar repeated administration regimens, long lasting brain dopaminergic changes are likely present in these monkeys. |
1986-06-17 |
2023-08-11 |
monkey |
| J Arita, F Kimur. Effect of aging on in vitro dopamine biosynthesis in the median eminence of rat hypothalamic slices. Brain research. vol 369. issue 1-2. 1986-06-13. PMID:3008942. |
however, the rate of ca2+-dependent, depolarization-induced dopa accumulation was smaller in aged rats, suggesting that the ca2+ system in the regulation of dopamine biosynthesis in tuberoinfundibular dopaminergic neurons is altered by aging. |
1986-06-13 |
2023-08-11 |
rat |
| O Serr. Somatotroph responsiveness to low dose dopamine infusion in normal subjects and acromegalic patients. Neuroendocrinology. vol 42. issue 6. 1986-06-11. PMID:3010156. |
we have investigated the effects of intravenous administration of a low dose of dopamine (da) on plasma growth hormone (gh) concentrations in acromegalic patients and normal subjects with the aim of defining the somatotroph responsiveness to peripheral (i.e., outside the blood-brain barrier) specific dopaminergic stimuli. |
1986-06-11 |
2023-08-11 |
human |
| M Parenti, C Flauto, E Parati, A Vescovi, A Groppett. Manganese neurotoxicity: effects of L-DOPA and pargyline treatments. Brain research. vol 367. issue 1-2. 1986-06-09. PMID:2421838. |
moreover, rats treated two weeks before with a dose of manganese chloride that produced a 70-80% drop in striatal dopamine concentrations, rotated ipsilaterally to the dopamine-depleted striatum when injected with apomorphine, suggesting that in these animals the stimulatory effects of apomorphine were more relevant in striatum where presynaptic dopaminergic neurons were not affected by manganese chloride. |
1986-06-09 |
2023-08-11 |
rat |
| G M Simpson, E H Pi, J J Srame. An update on tardive dyskinesia. Hospital & community psychiatry. vol 37. issue 4. 1986-06-09. PMID:2870977. |
supersensitivity of dopamine receptors is believed to be the cause of tardive dyskinesia, and treatment strategies have consisted of pharmacologic blockade of dopamine receptors, depletion of dopamine, and restoration of the balance between the dopaminergic system and the neurotransmitter systems that regulate it. |
1986-06-09 |
2023-08-11 |
Not clear |
| J P Bennett, G F Woote. Dopamine denervation does not alter in vivo 3H-spiperone binding in rat striatum: implications for external imaging of dopamine receptors in Parkinson's disease. Annals of neurology. vol 19. issue 4. 1986-06-09. PMID:3707090. |
striatal particulate preparations, both from rats with lesion-induced striatal dopamine (da) loss and from some striatal dopamine (da) loss and from some patients with parkinson's disease, exhibit increased 3h-neuroleptic binding, which is interpreted to be the mechanism of denervation-induced behavioral supersensitivity to dopaminergic compounds. |
1986-06-09 |
2023-08-11 |
rat |