| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T C Napier, B S Givens, D W Schulz, B S Bunney, G R Breese, R B Mailma. SCH23390 effects on apomorphine-induced responses of nigral dopaminergic neurons. The Journal of pharmacology and experimental therapeutics. vol 236. issue 3. 1986-04-18. PMID:3512819. |
this conclusion is drawn because: doses of sch23390 known to block behaviors caused by dopamine agonists were ineffective in blocking rate reductions produced by apomorphine and pretreatment with 0.1 mg/kg of sch23390 did not change the apomorphine dose-response curve for inhibition of dopaminergic neurons. |
1986-04-18 |
2023-08-11 |
Not clear |
| G Battaglia, A B Norman, E J Hess, I Crees. Forskolin potentiates the stimulation of rat striatal adenylate cyclase mediated by D-1 dopamine receptors, guanine nucleotides, and sodium fluoride. Journal of neurochemistry. vol 46. issue 4. 1986-04-16. PMID:3005508. |
with respect to 3,4-dihydroxyphenylethylamine (dopamine) receptor-mediated stimulation of striatal enzyme activity, the stimulation of enzyme activity by dopaminergic agonists, in the absence or presence of forskolin, was gtp-dependent and could be antagonized by the selective d-1 antagonist sch23390 (100 nm), indicating that these effects are mediated by d-1 dopamine receptors. |
1986-04-16 |
2023-08-11 |
rat |
| R Shikuma, M Yoshimura, S Kambara, H Yamazaki, R Takashina, H Takahashi, K Takeda, H Ijich. Dopaminergic modulation of salt sensitivity in patients with essential hypertension. Life sciences. vol 38. issue 10. 1986-04-15. PMID:3951317. |
to further evaluate the role of dopaminergic mechanisms in salt-sensitive hypertension, metoclopramide, a dopamine antagonist, was injected intravenously to all patients. |
1986-04-15 |
2023-08-11 |
Not clear |
| N Stern, M Tuck, L Ozaki, J F Kral. Dopaminergic binding and inhibitory effect in the bovine adrenal zona glomerulosa. Hypertension (Dallas, Tex. : 1979). vol 8. issue 3. 1986-04-11. PMID:3005168. |
we now report the identification of dopaminergic binding sites in the bovine adrenal zone glomerulosa using [3h]spiperone, a butyrophenone with high affinity for d2 dopamine receptors. |
1986-04-11 |
2023-08-11 |
rat |
| S W Johnson, B J Hoffer, R Freedma. Investigation of the failure of parenterally administered haloperidol to antagonize dopamine released from micropipettes in the caudate. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 6. issue 2. 1986-04-11. PMID:3081693. |
an anomaly in the experimental data underlying the theory that neuroleptics act by blockade of dopaminergic neurotransmission is the repeatedly demonstrated failure in several laboratories of parenterally administered neuroleptics to antagonize electrophysiologic actions of locally applied dopamine (da) in striatum. |
1986-04-11 |
2023-08-11 |
rat |
| S Narumi, Y Nagai, Y Saji, Y Nagaw. A possible mechanism of action of thyrotropin-releasing hormone (TRH) and its analog DN-1417 on the release of dopamine from the nucleus accumbens and striatum in rats. Japanese journal of pharmacology. vol 39. issue 4. 1986-04-08. PMID:2869169. |
slices of the nucleus accumbens, the terminus of the mesolimbic dopaminergic system and the striatum, the terminus of the nigrostriatal dopaminergic system obtained from rats, were used for analyzing the dopamine releasing effects of trh and its analog dn-1417 (gamma-butyrolactone-gamma-carbonyl-l-histidyl-l-prolinamide citrate). |
1986-04-08 |
2023-08-11 |
rat |
| A J Bradbury, B Costall, M E Kelly, R J Naylor, J A Smit. Biochemical correlates of motor changes caused by the manipulation of dopamine function in the substantia nigra of the mouse. Neuropharmacology. vol 24. issue 12. 1986-04-07. PMID:4094652. |
it is concluded that the action of dopamine agonists in the midbrain can decrease the functional activity in the ascending dopaminergic pathways. |
1986-04-07 |
2023-08-11 |
mouse |
| P van der Zee, W Hesp. Interaction between substituted 1-[2-(diphenylmethoxy)ethyl] piperazines and dopamine receptors. Neuropharmacology. vol 24. issue 12. 1986-04-07. PMID:4094653. |
current insight in structural requirements for binding to dopamine receptors, as obtained mainly with rigid analogues of dopamine, gives no satisfactory explanation for the dopaminergic activity of the piperazine derivatives tested. |
1986-04-07 |
2023-08-11 |
rat |
| C Missale, S Govoni, G Pasinetti, C Assini, P F Spano, F Battaini, M Trabucch. Age-dependent changes in the mechanisms regulating dopamine uptake in the central nervous system. Journal of gerontology. vol 41. issue 2. 1986-04-03. PMID:3950337. |
na+-dependent binding of 3h-cocaine is located on dopaminergic terminals and is related to the dopamine uptake system. |
1986-04-03 |
2023-08-11 |
rat |
| D Cocchi, C Castoldi, S Locatelli, A Novelli, A M Colombo, A Tammaro, E E Mülle. Evaluation of hypothalamic dopaminergic function by neuropharmacologic means in aged women. Journal of neural transmission. vol 64. issue 3-4. 1986-03-26. PMID:3003250. |
the function of the hypothalamic tuberoinfundibular dopaminergic (tida) neurons involved in the control of prolactin secretion was investigated in aged subjects with the use of nomifensine, an indirect-acting dopamine (da) agonist, domperidone, a da receptor antagonist, and da, which acts directly on the pituitary lactotropes. |
1986-03-26 |
2023-08-11 |
human |
| E Przegaliński, L Baran, J Siwanowicz, G Nowak, L Antkiewicz-Michaluk, J Vetulan. Chronic treatment with the potential antidepressant drug rolipram: the effect on the behavioural responses to adrenergic and dopaminergic receptor agonists with some biochemical correlates. Journal of neural transmission. vol 64. issue 3-4. 1986-03-26. PMID:3003251. |
we studied the effect of acute and chronic treatment with rolipram, a potential antidepressant drug, on the behavioural responses induced by adrenergic and dopaminergic receptor agonists in mice and rats, and on (3h)prazosin and (3h)dihydroalprenolol binding to cortical membranes and whole brain noradrenaline and dopamine utilization in rats. |
1986-03-26 |
2023-08-11 |
mouse |
| T J Walsh, D W Schulz, H A Tilson, D L Dehave. Acute exposure to triethyl lead enhances the behavioral effects of dopaminergic agonists: involvement of brain dopamine in organolead neurotoxicity. Brain research. vol 363. issue 2. 1986-03-24. PMID:3942894. |
acute exposure to triethyl lead enhances the behavioral effects of dopaminergic agonists: involvement of brain dopamine in organolead neurotoxicity. |
1986-03-24 |
2023-08-11 |
rat |
| J P Herman, K Choulli, M Le Moa. Activation of striatal dopaminergic grafts by haloperidol. Brain research bulletin. vol 15. issue 6. 1986-03-21. PMID:3936594. |
the effect of haloperidol (0.5 mg/kg, 60 min) on striatal dopamine metabolism of intact rats and of rats bearing a dopaminergic graft implanted into the previously denervated striatum was investigated. |
1986-03-21 |
2023-08-11 |
rat |
| J P Herman, K Choulli, M Le Moa. Activation of striatal dopaminergic grafts by haloperidol. Brain research bulletin. vol 15. issue 6. 1986-03-21. PMID:3936594. |
the dopaminergic grafts increased dopamine and dihydroxyphenylacetic acetic acid (dopac) contents to 6.2 and 9.6% of their respective control levels (lesioned striatum: 0.5 and 0.7% respectively). |
1986-03-21 |
2023-08-11 |
rat |
| R B Barnes, K Y Cha, D G Lee, R A Lob. Modulation of luteinizing hormone immunoreactivity and bioactivity by dopamine but not norepinephrine in women. American journal of obstetrics and gynecology. vol 154. issue 2. 1986-03-21. PMID:3946528. |
these data suggest that although endogenous dopaminergic blockade may not play a significant role in determining basal levels of luteinizing hormone, decreases in dopamine at the pituitary level may increase the bioactive/immunoreactive luteinizing hormone ratio. |
1986-03-21 |
2023-08-11 |
Not clear |
| D Leys, P Bourgeois, A Destée, H Peti. [Acute choreic syndrome and psychotic state induced by an amphetaminic drug]. Revue neurologique. vol 141. issue 6-7. 1986-03-19. PMID:4089413. |
the mechanisms of these acute manifestations are discussed: oral contraceptives increase striatal post-synaptic dopaminergic sensitivity, while amphetamines facilitate the dopamine release in striatum. |
1986-03-19 |
2023-08-11 |
Not clear |
| P Carnoy, P Soubrie, A J Puech, P Simo. Performance deficit induced by low doses of dopamine agonists in rats. Toward a model for approaching the neurobiology of negative schizophrenic symptomatology? Biological psychiatry. vol 21. issue 1. 1986-03-13. PMID:2867789. |
if this deficit is due to decreased dopaminergic transmission produced by low doses of dopamine agonists, our model might suggest that some symptoms of schizophrenia (anhedonia for instance) are not incompatible with deficient dopaminergic transmission. |
1986-03-13 |
2023-08-11 |
rat |
| J A Obeso, M R Luquin, J M Martínez Lag. Intravenous lisuride corrects oscillations of motor performance in Parkinson's disease. Annals of neurology. vol 19. issue 1. 1986-03-11. PMID:3947037. |
lisuride appears to be one of the best available dopamine agonists for continuous dopaminergic stimulation. |
1986-03-11 |
2023-08-11 |
Not clear |
| J J Kyncl, S A Buckner, H Brondyk, D J Kerkman, J F DeBernardis, E N Bush, O Kuche. Adrenergic and dopaminergic properties of dopamine sulfoconjugates. Journal of cardiovascular pharmacology. vol 7. issue 6. 1986-03-05. PMID:2418311. |
adrenergic and dopaminergic properties of dopamine sulfoconjugates. |
1986-03-05 |
2023-08-11 |
dog |
| J J Kyncl, S A Buckner, H Brondyk, D J Kerkman, J F DeBernardis, E N Bush, O Kuche. Adrenergic and dopaminergic properties of dopamine sulfoconjugates. Journal of cardiovascular pharmacology. vol 7. issue 6. 1986-03-05. PMID:2418311. |
in anesthetized dogs the two compounds failed to stimulate either the dopaminergic receptors (da-1) of mesenteric vascular beds or the adrenergic receptors mediating the vasodilatory and pressor responses to dopamine. |
1986-03-05 |
2023-08-11 |
dog |