| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Closse, W Frick, R Markstein, R Maurer, R Nordman. [3H]205-501, a non-catechol dopaminergic agonist, labels selectively and with high affinity dopamine D2 receptors. Journal of neural transmission. vol 62. issue 3-4. 1985-09-27. PMID:3161996. |
pki values of dopaminergic agonists derived from competition isotherms in the [3h]205-501 binding assay correlate very well with their potency in the acetylcholine release assay, which is controlled by dopamine d2 receptors. |
1985-09-27 |
2023-08-11 |
Not clear |
| J G Cannon, C Koble-Suarez, J P Long, M Ilhan, R K Bhatnaga. Cis- and trans-4-n-Propyl-1,2,3,4,4a,5,6,10b-octahydrobenzo(f)quinolines. Journal of pharmaceutical sciences. vol 74. issue 6. 1985-09-25. PMID:4040568. |
cis- and trans-4-n-propyloctahydrobenzo(f)quinolines 4a,b were prepared for further assessment of dopaminergic effects of non-oxygenated dopamine congeners. |
1985-09-25 |
2023-08-11 |
rat |
| R Sommerville, H E Rosenberg, P A Crook. Synthesis and pharmacological evaluation of aromatic dihydroxylated spiro[indan-1,3'-pyrrolidine] and spiro[indan-2,2'-pyrrolidine] derivatives. Journal of pharmaceutical sciences. vol 74. issue 5. 1985-09-23. PMID:4020632. |
none of these conformationally restricted catecholamines possessed any dopaminergic activity, but 5,6-dihydroxy spiro[indan-1,3'-pyrrolidine] hydrobromide exhibited weak dopamine antagonist properties. |
1985-09-23 |
2023-08-11 |
Not clear |
| M Rosolowsky, H R Weis. Effect of dopamine and blockade of dopaminergic and adrenergic receptors on coronary blood flow in ischemic rabbit myocardium. Journal of cardiovascular pharmacology. vol 7. issue 4. 1985-09-19. PMID:2410711. |
effect of dopamine and blockade of dopaminergic and adrenergic receptors on coronary blood flow in ischemic rabbit myocardium. |
1985-09-19 |
2023-08-11 |
rabbit |
| M Rosolowsky, H R Weis. Effect of dopamine and blockade of dopaminergic and adrenergic receptors on coronary blood flow in ischemic rabbit myocardium. Journal of cardiovascular pharmacology. vol 7. issue 4. 1985-09-19. PMID:2410711. |
dopamine, 10, 100, or 1,000 micrograms/kg/min, was infused in the presence of dopaminergic, beta-, or alpha-adrenergic receptor blockade. |
1985-09-19 |
2023-08-11 |
rabbit |
| M Rosolowsky, H R Weis. Effect of dopamine and blockade of dopaminergic and adrenergic receptors on coronary blood flow in ischemic rabbit myocardium. Journal of cardiovascular pharmacology. vol 7. issue 4. 1985-09-19. PMID:2410711. |
it can be concluded that direct or indirect vasodilator receptors (dopaminergic, beta 1-, and beta 2-adrenoceptors) must be stimulated and perfusion pressure must not fall in order for dopamine to produce increases of coronary blood flow within occluded myocardium. |
1985-09-19 |
2023-08-11 |
rabbit |
| H Schoemaker, C Pimoule, S Arbilla, B Scatton, F Javoy-Agid, S Z Lange. Sodium dependent [3H]cocaine binding associated with dopamine uptake sites in the rat striatum and human putamen decrease after dopaminergic denervation and in Parkinsons disease. Naunyn-Schmiedeberg's archives of pharmacology. vol 329. issue 3. 1985-09-19. PMID:3927176. |
sodium dependent [3h]cocaine binding associated with dopamine uptake sites in the rat striatum and human putamen decrease after dopaminergic denervation and in parkinsons disease. |
1985-09-19 |
2023-08-11 |
human |
| G R Breese, T C Napier, R A Muelle. Dopamine agonist-induced locomotor activity in rats treated with 6-hydroxydopamine at differing ages: functional supersensitivity of D-1 dopamine receptors in neonatally lesioned rats. The Journal of pharmacology and experimental therapeutics. vol 234. issue 2. 1985-09-17. PMID:3926987. |
these results indicate that d-1 dopamine receptors contribute to modulation of central dopaminergic function. |
1985-09-17 |
2023-08-11 |
rat |
| H Fink, R Morgenster. Locomotor effects of lisuride: a consequence of dopaminergic and serotonergic actions. Psychopharmacology. vol 85. issue 4. 1985-09-12. PMID:2991961. |
it is concluded that the locomotor stimulant effect of higher doses of lisuride may depend on stimulation of postsynaptic dopamine receptors and a serotonergic action and that the locomotor effects of lisuride reflect a complex interaction at dopaminergic and serotonergic transmission systems. |
1985-09-12 |
2023-08-11 |
rat |
| A R Artalejo, A G García, C Montiel, P Sánchez-Garcí. A dopaminergic receptor modulates catecholamine release from the cat adrenal gland. The Journal of physiology. vol 362. 1985-09-12. PMID:4020691. |
the fact that dopamine is released in measurable amounts, together with adrenaline and noradrenaline, from perfused cat adrenal glands in response to nicotinic stimulation (v. ceña, unpublished results), favours a role for this dopaminergic receptor in modulating catecholamine release from the chromaffin cell. |
1985-09-12 |
2023-08-11 |
cat |
| S Koyama, M Sasaki, T Setoyama, K Takahashi, K Togashi, K Suzuki, N Kakki, M Ima. Dopaminergic modulation of the renal effect of arginine-vasopressin in water-loaded rats. Japanese journal of pharmacology. vol 38. issue 1. 1985-09-11. PMID:4021228. |
these observations support the view that dopamine inhibits the antidiuretic action of vasopressin by dopaminergic receptors also in the mammalian kidney. |
1985-09-11 |
2023-08-11 |
rat |
| S R George, M Watanabe, T Di Paolo, P Falardeau, F Labrie, P Seema. The functional state of the dopamine receptor in the anterior pituitary is in the high affinity form. Endocrinology. vol 117. issue 2. 1985-08-29. PMID:4017954. |
in order to determine whether the high affinity state or the low affinity state of the dopamine receptor mediated the inhibition of release of prl by dopamine agonists, a large number of dopaminergic agonists (n = 31) and antagonists (n = 24) were tested for their potencies to inhibit the binding of [3h] spiperone to porcine anterior pituitary tissue, and for their potencies to affect the release of prl from rat anterior pituitary cells in culture. |
1985-08-29 |
2023-08-11 |
rat |
| D G Kirch, M R Palmer, M Egan, R Freedma. Electrophysiological interactions between haloperidol and reduced haloperidol, and dopamine, norepinephrine and phencyclidine in rat brain. Neuropharmacology. vol 24. issue 5. 1985-08-26. PMID:2862598. |
phencyclidine, which is an indirect dopaminergic agonist in the caudate, caused inhibition of the discharges of caudate neurons resembling that induced by dopamine itself. |
1985-08-26 |
2023-08-11 |
rat |
| J Barber, R Tomer, H Sroka, M S Myslobodsk. Does unilateral dopamine deficit contribute to depression? Psychiatry research. vol 15. issue 1. 1985-08-22. PMID:3859881. |
given that dopaminergic pathways are involved in affective behavior, depression, which is recognized as an integral part of parkinson's disease, may be associated with a dopamine imbalance. |
1985-08-22 |
2023-08-11 |
Not clear |
| K Toide, N Unemi, T Segaw. Effects of a fluorinated pyrimidinedione anti-cancer drug, 5-fluoro-1-(tetrahydro-2-furanyl)-2,4-pyrimidinedione (FT), and related compounds on nigro-striatal dopaminergic neurons in the central nervous system. Archives internationales de pharmacodynamie et de therapie. vol 274. issue 1. 1985-08-22. PMID:3925907. |
these results suggest that the side effects of ft on the cns, especially its action on dopaminergic neurons, may result from blockade of pre- and post-synaptic dopamine receptors, and may be mediated by its main metabolite 5-fu in the brain. |
1985-08-22 |
2023-08-11 |
rat |
| J S Ramsdell, C L Bethea, R B Jaffe, C B Wilson, R I Weine. Characterization of dopamine and alpha-adrenergic receptors in human prolactin-secreting adenomas with [3H]-dihydroergocryptine. Neuroendocrinology. vol 40. issue 6. 1985-08-21. PMID:2861582. |
dopamine receptors have been repeatedly characterized on prolactin-secreting adenomas using labelled antagonists as ligands; however, no data are available on characterization of the receptor with a dopaminergic agonist. |
1985-08-21 |
2023-08-11 |
human |
| J Arnt, A V Christensen, J Hytte. Pharmacology in vivo of the phenylindan derivative, Lu 19-005, a new potent inhibitor of dopamine, noradrenaline and 5-hydroxytryptamine uptake in rat brain. Naunyn-Schmiedeberg's archives of pharmacology. vol 329. issue 2. 1985-08-13. PMID:2409454. |
behavioural effects on dopaminergic transmission of a phenylindane derivative, lu 19-005 [(+/-)-trans-3-(3,4-dichlorophenyl)-n-methyl-l-indanamine, hci], with potent inhibitory effect on dopamine (da), noradrenaline (na) and serotonin (5-ht) uptake in rats and the effect on da, na and 5-ht activity in mice have been studied and compared with those of other known da, na and 5-ht uptake inhibitors with different selectivity ratios. |
1985-08-13 |
2023-08-11 |
mouse |
| S Nagahama, Y F Chen, S Opari. Enhanced depressor effect of bromocriptine in the DOCA/NaCl hypertensive rat. The American journal of physiology. vol 249. issue 1 Pt 2. 1985-08-13. PMID:2861750. |
to elucidate the role of the dopaminergic system in the maintenance of hypertension in the deoxycorticosterone acetate (doca)/nacl hypertensive rat, the responses of mean arterial pressure (map), plasma norepinephrine (ne), epinephrine (e), and prolactin (prl) to intravenous (iv) administration of bromocriptine, a dopamine agonist, and hexamethonium bromide, a ganglion blocker, were examined in conscious, unrestrained 4-wk doca/nacl hypertensive rats. |
1985-08-13 |
2023-08-11 |
rat |
| G W Maguire, E L Smit. Cat retinal ganglion cell receptive-field alterations after 6-hydroxydopamine induced dopaminergic amacrine cell lesions. Journal of neurophysiology. vol 53. issue 6. 1985-08-12. PMID:2861256. |
the impairment of the dopaminergic ac was verified by high pressure-liquid chromatography (hplc) with electrochemical detection of endogenous dopamine content and by [3h]dopamine high-affinity uptake; the dopaminergic acs of the treated eyes demonstrated reduced endogenous dopamine content and reduced [3h]dopamine uptake compared with that of their matched controls. |
1985-08-12 |
2023-08-11 |
cat |
| C J Schmidt, J K Ritter, P K Sonsalla, G R Hanson, J W Gib. Role of dopamine in the neurotoxic effects of methamphetamine. The Journal of pharmacology and experimental therapeutics. vol 233. issue 3. 1985-08-09. PMID:2409267. |
these results suggest that dopamine plays an important role in the changes mediated by the administration of methamphetamine in both the dopaminergic and serotonergic systems. |
1985-08-09 |
2023-08-11 |
rat |