| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A F Sved, H A Baker, D J Rei. Dopamine synthesis in inbred mouse strains which differ in numbers of dopamine neurons. Brain research. vol 303. issue 2. 1984-08-30. PMID:6744023. |
balb/cj and cba/j mice have been shown to have different numbers of dopamine (da) neurons in the central nervous system, with balb/cj mice having 20-50% more da neurons in each dopaminergic cell group which is reflected in a difference in tyrosine hydroxylase activity in these cell groups. |
1984-08-30 |
2023-08-12 |
mouse |
| G A Ricaurte, L S Seiden, C R Schuste. Further evidence that amphetamines produce long-lasting dopamine neurochemical deficits by destroying dopamine nerve fibers. Brain research. vol 303. issue 2. 1984-08-30. PMID:6744029. |
to determine whether this fiber degeneration induced by amphetamines was dopaminergic, the long-lasting dopamine depletion produced by methamphetamine was antagonized with alpha-methyl-para-tyrosine. |
1984-08-30 |
2023-08-12 |
rat |
| B Turowski, M Szkrybalo, K Anderson, D Miller, N Uretsk. Effect of a sulfonium analog of dopamine on the depolarization-induced release of [3H]acetylcholine from mouse striatal slices. Biochemical pharmacology. vol 33. issue 15. 1984-08-29. PMID:6466358. |
the release of [3h]dopamine by the sulfonium analog was inhibited by cocaine (3 microm), suggesting that the drug-induced release of [3h]dopamine was dependent on the carrier-mediated uptake of the sulfonium analog into dopaminergic neurons. |
1984-08-29 |
2023-08-12 |
mouse |
| J A Javitch, R O Blaustein, S H Snyde. [3H]mazindol binding associated with neuronal dopamine and norepinephrine uptake sites. Molecular pharmacology. vol 26. issue 1. 1984-08-27. PMID:6087116. |
the association of [3h]mazindol binding sites with neuronal dopamine uptake sites in the corpus striatum is further supported by the reduction of [3h]mazindol binding sites in striatal membranes following destruction of dopaminergic neurons by 6-hydroxydopamine. |
1984-08-27 |
2023-08-12 |
Not clear |
| M J Zigmond, A L Acheson, M K Stachowiak, E M Stricke. Neurochemical compensation after nigrostriatal bundle injury in an animal model of preclinical parkinsonism. Archives of neurology. vol 41. issue 8. 1984-08-27. PMID:6147127. |
in our studies, damage to the nigrostriatal bundle of the rat, resulting in the loss of up to 95% of the dopaminergic terminals in striatum, was accompanied by apparent increases in the synthesis and release of dopamine (da) from those dopaminergic terminals that remained. |
1984-08-27 |
2023-08-12 |
rat |
| M Schultzberg, S B Dunnett, A Björklund, U Stenevi, T Hökfelt, G J Dockray, M Goldstei. Dopamine and cholecystokinin immunoreactive neurons in mesencephalic grafts reinnervating the neostriatum: evidence for selective growth regulation. Neuroscience. vol 12. issue 1. 1984-08-24. PMID:6146944. |
these results indicate that the dopaminergic reinnervation of the denervated neostriatum is preferentially carried out by the population of grafted mesencephalic dopamine neurones apparently lacking the cholecystokinin-like peptide. |
1984-08-24 |
2023-08-12 |
rat |
| K J Lookingland, K E Moor. Dopamine receptor-mediated regulation of incertohypothalamic dopaminergic neurons in the male rat. Brain research. vol 304. issue 2. 1984-08-24. PMID:6331589. |
dopamine receptor-mediated regulation of incertohypothalamic dopaminergic neurons in the male rat. |
1984-08-24 |
2023-08-12 |
rat |
| L A Chiodo, M J Bannon, A A Grace, R H Roth, B S Bunne. Evidence for the absence of impulse-regulating somatodendritic and synthesis-modulating nerve terminal autoreceptors on subpopulations of mesocortical dopamine neurons. Neuroscience. vol 12. issue 1. 1984-08-24. PMID:6462443. |
the dopaminergic nature of those mesocortical neurons insensitive to apomorphine and dopamine was confirmed using combined intracellular recording and catecholamine histofluorescence techniques. |
1984-08-24 |
2023-08-12 |
Not clear |
| J L Imbs, M Schmidt, J D Ehrhardt, J Schwart. The sympathetic nervous system and renal sodium handling: is dopamine involved? Journal of cardiovascular pharmacology. vol 6 Suppl 1. 1984-08-23. PMID:6204137. |
the presence of vascular dopamine receptors and dopaminergic nervous fibers in the kidney suggests that dopamine plays a role in the control of renal function by the autonomic nervous system. |
1984-08-23 |
2023-08-12 |
Not clear |
| S Swart, B P O'Malley, J Vora, D B Barnett, F D Rosentha. The effects of dopaminergic blockade on serum TSH and prolactin levels in thyrotoxicosis. Acta endocrinologica. vol 106. issue 3. 1984-08-20. PMID:6429989. |
in the first part of this study, we have demonstrated that, in 7 patients with untreated thyrotoxicosis, a 7 day regime of the long acting dopamine antagonist metoclopramide (10 mg orally 8 hourly) produces more adequate dopaminergic blockade at pituitary level than a single oral 10 mg dose of the compound as assessed by serum prolactin responses. |
1984-08-20 |
2023-08-12 |
human |
| R Prado-Alcala, A Streather, R A Wis. Brain stimulation reward and dopamine terminal fields. II. Septal and cortical projections. Brain research. vol 301. issue 2. 1984-08-17. PMID:6733491. |
variations in self-stimulation threshold were seen as electrodes were moved through homogeneous regions of dopamine terminal density in some regions, while stable thresholds were associated with movements through areas of varying dopamine terminal density in others; thus, again, there was no special relation between goodness of self-stimulation and density of dopaminergic innervation. |
1984-08-17 |
2023-08-12 |
Not clear |
| M J Zigmond, E M Stricke. Parkinson's disease: studies with an animal model. Life sciences. vol 35. issue 1. 1984-08-14. PMID:6146085. |
it appears that the loss of dopaminergic neurons is accompanied by an exponential increase in the ratio of tyrosine hydroxylase activity to dopamine content. |
1984-08-14 |
2023-08-12 |
rat |
| M Warnhof. Simultaneous determination of norepinephrine, dopamine, 5-hydroxytryptamine and their main metabolites in rat brain using high-performance liquid chromatography with electrochemical detection. Enzymatic hydrolysis of metabolites prior to chromatography. Journal of chromatography. vol 307. issue 2. 1984-08-13. PMID:6203923. |
in order to measure turnover rates of the noradrenergic, dopaminergic, and serotonergic transmitter systems in rat brain, a method was developed by which norepinephrine, dopamine, and 5-hydroxytryptamine, and their main metabolites 3-methoxy-4-hydroxyphenylglycol, 3,4-dihydroxyphenylacetic acid, 3-methoxy-4-hydroxyphenylacetic acid, and 5-hydroxyindole-3-acetic acid, could be measured simultaneously. |
1984-08-13 |
2023-08-12 |
rat |
| L Peyrin, H Simon, J M Cottet-Emard, N Bruneau, M Le Moa. 6-Hydroxydopamine lesions of dopaminergic A10 neurons. Long-term effects on the urinary excretion of free and conjugated catecholamines and their metabolites in the rat. Brain research. vol 235. issue 2. 1984-08-13. PMID:6821353. |
free and conjugated catecholamines (dopamine, noradrenaline, adrenaline) and their methoxylated and/or deaminated metabolites were studied in rat urine after the bilateral destruction of the a10 dopaminergic cell group. |
1984-08-13 |
2023-08-12 |
rat |
| H Taquet, F Javoy-Agid, F Cesselin, M Hamon, J C Legrand, Y Agi. Microtopography of methionine-enkephalin, dopamine and noradrenaline in the ventral mesencephalon of human control and Parkinsonian brains. Brain research. vol 235. issue 2. 1984-08-13. PMID:7188329. |
this observation, together with the close topographical association of dopamine and met-enkephalin in the substantia nigra, further supports the likely existence of important functional relationships between dopaminergic and enkephalinergic neurons in the human brain. |
1984-08-13 |
2023-08-12 |
human |
| R L Cooper, I J Constable, L Davidso. Aqueous humor catecholamines. Current eye research. vol 3. issue 6. 1984-08-07. PMID:6734261. |
this may explain the presence of aqueous humor dopamine and the effects of dopaminergic drugs on intraocular pressure. |
1984-08-07 |
2023-08-12 |
human |
| B Bokobza, M Ruberg, B Scatton, F Javoy-Agid, Y Agi. [3H]spiperone binding, dopamine and HVA concentrations in Parkinson's disease and supranuclear palsy. European journal of pharmacology. vol 99. issue 2-3. 1984-08-07. PMID:6734727. |
the density of d2-type dopamine receptors, measured by the binding of [3h]spiperone was normal in the substantia nigra, caudate nucleus and nucleus accumbens of parkinsonian subjects and above control levels in the putamen, in spite of massive lesions of the dopaminergic neurons. |
1984-08-07 |
2023-08-12 |
human |
| D K Sarkar, P E Gottschall, Q W Xie, J Meite. Reduced tuberoinfundibular dopaminergic neuronal function in rats with in situ prolactin-secreting pituitary tumors. Neuroendocrinology. vol 38. issue 6. 1984-08-07. PMID:6738813. |
tuberoinfundibular dopaminergic (tida) neuronal function in rats with spontaneous or estrogen-induced prolactin- (prl-)secreting pituitary tumors (prolactinomas) was studied by assaying dopamine (da) concentration in pituitary stalk blood and electrically induced release of 3h-da from the median eminence in vitro. |
1984-08-07 |
2023-08-12 |
rat |
| H Sjövall, S Redfors, B Biber, M Jodal, O Lundgre. Effect of intravenous dopamine infusion on intramural blood flow distribution and fluid absorption in the feline small intestine. Scandinavian journal of gastroenterology. vol 19. issue 3. 1984-08-01. PMID:6740217. |
the findings indicate that dopamine induces a mucosal vasodilation via one mechanism (possibly dopaminergic) and enhances fluid transport via another mechanism, probably alpha-adrenergic. |
1984-08-01 |
2023-08-12 |
Not clear |
| K Bech, C P Hovendal, F Gottrup, D Anderse. Dopaminergic and beta-adrenergic effects on gastric antral motility. Scandinavian journal of gastroenterology. Supplement. vol 89. 1984-07-27. PMID:6146195. |
dopamine was used alone and in conjunction with selective blockade of adrenergic and dopaminergic receptors during infusion of bethanechol or pentagastrin inducing motor activity patterns as in the phase iii of the mmc and the digestive state respectively. |
1984-07-27 |
2023-08-12 |
Not clear |