| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Masaya Harada, Laia Serratosa Capdevila, Maria Wilhelm, Denis Burdakov, Tommaso Patriarch. Stimulation of VTA dopamine inputs to LH upregulates orexin neuronal activity in a DRD2-dependent manner. eLife. vol 12. 2024-04-03. PMID:38567902. |
furthermore, orexin neuron activity could also be upregulated by local stimulation of dopaminergic terminals in the lh in a way that is partially dependent on dopamine d2 receptors (drd2). |
2024-04-03 |
2024-04-05 |
mouse |
| Seong-Jin Yu, Yun Wang, Hui Shen, Eun-Kyung Bae, Yazhou Li, Kumar Sambamurti, Michael A Tones, Margaret M Zaleska, Barry J Hoffer, Nigel H Grei. DPP-4 inhibitors sitagliptin and PF-00734,200 mitigate dopaminergic neurodegeneration, neuroinflammation and behavioral impairment in the rat 6-OHDA model of Parkinson's disease. GeroScience. 2024-04-02. PMID:38563864. |
measures of dopaminergic cell viability, dopamine content, neuroinflammation and neurogenesis were evaluated thereafter in ipsi- and contralateral brain. |
2024-04-02 |
2024-04-04 |
human |
| Maya Molinari, Ori J Lieberman, David Sulzer, Emanuela Santini, Anders Borgkvis. 5-HT1B receptors mediate dopaminergic inhibition of vesicular fusion and GABA release from striatonigral synapses. bioRxiv : the preprint server for biology. 2024-04-01. PMID:38559006. |
the substantia nigra pars reticulata (snr), a crucial basal ganglia output nucleus, contains a dense expression of dopamine d1 receptors (d1rs), along with dendrites belonging to dopaminergic neurons of substantia nigra pars compacta. |
2024-04-01 |
2024-04-04 |
Not clear |
| Meghan L Bucher, Amy R Dunn, Joshua M Bradner, Kristen Stout Egerton, James P Burkett, Michelle A Johnson, Gary W Mille. Synaptic vesicle glycoprotein 2C enhances vesicular storage of dopamine and counters dopaminergic toxicity. The European journal of neuroscience. 2024-03-27. PMID:38532289. |
synaptic vesicle glycoprotein 2c enhances vesicular storage of dopamine and counters dopaminergic toxicity. |
2024-03-27 |
2024-03-29 |
mouse |
| Natchadaporn Sorraksa, Palakorn Kaokaen, Phongsakorn Kunhorm, Nudjanad Heebkaew, Wilasinee Promjantuek, Parinya Nois. Rapid induction of dopaminergic neuron-like cells from human fibroblasts by autophagy activation with only 2-small molecules. 3 Biotech. vol 14. issue 4. 2024-03-25. PMID:38524239. |
the dopaminergic neurons are responsible for the release of dopamine. |
2024-03-25 |
2024-03-27 |
human |
| Natchadaporn Sorraksa, Palakorn Kaokaen, Phongsakorn Kunhorm, Nudjanad Heebkaew, Wilasinee Promjantuek, Parinya Nois. Rapid induction of dopaminergic neuron-like cells from human fibroblasts by autophagy activation with only 2-small molecules. 3 Biotech. vol 14. issue 4. 2024-03-25. PMID:38524239. |
different proteins and factors related to dopaminergic neurons (th, tuj1, and dopamine) were significantly increased in cells that behave like dopaminergic neurons after treatment. |
2024-03-25 |
2024-03-27 |
human |
| Aineng Peng, Jianbo Chai, Haiyuan Wu, Bing Bai, Huihui Yang, Weizhi He, Yonghou Zha. New Therapeutic Targets and Drugs for Schizophrenia Beyond Dopamine D2 Receptor Antagonists. Neuropsychiatric disease and treatment. vol 20. 2024-03-25. PMID:38525480. |
the first generation of antipsychotics was developed based on dopaminergic receptor antagonism, which blocks dopamine d2 receptors in the brain to exert antipsychotic effects. |
2024-03-25 |
2024-03-27 |
Not clear |
| Sheena K Au-Yeung, Don Chamith Halahakoon, Alexander Kaltenboeck, Philip Cowen, Michael Browning, Sanjay G Manoha. The effects of pramipexole on motivational vigour during a saccade task: a placebo-controlled study in healthy adults. Psychopharmacology. 2024-03-18. PMID:38494550. |
this effect, termed motivational vigour, has been proposed to rely on central dopamine, with dopaminergic agents showing promise in the treatment of depression. |
2024-03-18 |
2024-03-20 |
human |
| Dianmei Yu, Haiyan Wang, Yiwen Zhai, Zhixiang Lei, Minglu Sun, Si Chen, Panfeng Yin, Xianchun Wan. Effects of latroeggtoxin-VI on dopamine and α-synuclein in PC12 cells and the implications for Parkinson's disease. Biological research. vol 57. issue 1. 2024-03-16. PMID:38491377. |
parkinson's disease (pd) is characterized by death of dopaminergic neurons leading to dopamine deficiency, excessive α-synuclein facilitating lewy body formation, etc. |
2024-03-16 |
2024-03-19 |
spider |
| Xiaojuan Lu, Yixing Song, Jiaqi Wang, Yunyun Cai, Siwan Peng, Jiaqi Lin, Biqin Lai, Junjie Sun, Tianqing Liu, Gang Chen, Lingyan Xin. Developmental dopaminergic signaling modulates neural circuit formation and contributes to autism spectrum disorder (ASD)-related phenotypes. The American journal of pathology. 2024-03-16. PMID:38492733. |
these findings shed light on the mechanisms underlying the link between disrupted developmental dopamine signaling and asd, and they point to the possibility of targeting dopaminergic signaling in early development for asd treatment. |
2024-03-16 |
2024-03-19 |
human |
| Sherilyn Junelle Recinto, Shobina Premachandran, Sriparna Mukherjee, Alexis Allot, Adam MacDonald, Moein Yaqubi, Samantha Gruenheid, Louis-Eric Trudeau, Jo Anne Stratto. Characterizing enteric neurons in dopamine transporter (DAT)-Cre reporter mice reveals dopaminergic subtypes with dual-transmitter content. The European journal of neuroscience. 2024-03-15. PMID:38487941. |
characterizing enteric neurons in dopamine transporter (dat)-cre reporter mice reveals dopaminergic subtypes with dual-transmitter content. |
2024-03-15 |
2024-03-17 |
mouse |
| Wan-Hsuan Chang, Hung-Te Hsu, Chih-Cheng Lin, Li-Mei An, Chien-Hsing Lee, Horng-Huey Ko, Chih-Lung Lin, Yi-Ching L. Linalool, a Fragrance Compound in Plants, Protects Dopaminergic Neurons and Improves Motor Function and Skeletal Muscle Strength in Experimental Models of Parkinson's Disease. International journal of molecular sciences. vol 25. issue 5. 2024-03-13. PMID:38473763. |
parkinson's disease (pd) is a common neurodegenerative disorder characterized by the gradual loss of dopaminergic neurons in the substantia nigra pars compacta (snpc), resulting in reduced dopamine levels in the striatum and eventual onset of motor symptoms. |
2024-03-13 |
2024-03-15 |
Not clear |
| Ayaka Morigami, Ken Sasak. Physiological specialization of the brain in bumble bee castes: Roles of dopamine in mating-related behaviors in female bumble bees. PloS one. vol 19. issue 3. 2024-03-13. PMID:38478476. |
these results suggest that dopamine plays important roles in gyne-specific behavior in bumble bees and has a common dopaminergic function in female eusocial bees. |
2024-03-13 |
2024-03-16 |
bee |
| Kanika Bhardwaj, Neelu Kanwar Rajawat, Nupur Mathu. Development of Alpha-Synuclein protein model against therapeutic aspects of Parkinson's disease. Indian journal of pharmacology. vol 56. issue 1. 2024-03-08. PMID:38454587. |
journal/ijpha/04.03/01363791-202456010-00007/figure1/v/2024-03-07t095025z/r/image-tiff parkinson's disease (pd) is the most common neurodegenerative disease caused by the steady depletion of dopamine in the striatum due to the loss of dopaminergic neurons. |
2024-03-08 |
2024-03-10 |
Not clear |
| Alagudurai Krishnamoorthy, Riddhi Upadhyay, Murugan Sevana. Chrysin for Neurotrophic and Neurotransmitter Balance in Parkinson's Disease. Methods in molecular biology (Clifton, N.J.). vol 2761. 2024-03-01. PMID:38427256. |
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) has a direct impact on the dopaminergic neurons in the substantia nigra pars compacta (snpc), dopamine in the striatum (st), homovanillic acid (hva), neurotrophic factors of the snpc, and st regions leading to parkinson's disease (pd). |
2024-03-01 |
2024-03-03 |
mouse |
| Florina Madalina Mindru, Andrei-Flavius Radu, Adrian Gheorghe Bumbu, Ada Radu, Simona Gabriela Bunga. Insights into the Medical Evaluation of Ekbom Syndrome: An Overview. International journal of molecular sciences. vol 25. issue 4. 2024-02-24. PMID:38396826. |
its pathophysiological mechanism involves uncertain dopaminergic imbalances and dysfunction in the dopamine transporter system. |
2024-02-24 |
2024-02-26 |
Not clear |
| Lingling Zhang, Hao Yan. Research progress of neural stem cells as a source of dopaminergic neurons for cell therapy in Parkinson's disease. Molecular biology reports. vol 51. issue 1. 2024-02-24. PMID:38400887. |
parkinson's disease (pd) is a neurodegenerative disease, the most characteristic pathological feature is the progressive loss of dopaminergic (da) neurons in the substantia nigra pars compactus (snpc) of the mesencephalon, along with reduced dopamine content in the striatum. |
2024-02-24 |
2024-02-27 |
Not clear |
| Mateusz Toś, Anna Grażyńska, Sofija Antoniuk, Joanna Siud. Impulse Control Disorders in Parkinson's Disease and Atypical Parkinsonian Syndromes-Is There a Difference? Brain sciences. vol 14. issue 2. 2024-02-23. PMID:38391755. |
icds are known non-motor symptoms in parkinson's disease (pd) and are associated primarily with the use of dopaminergic treatment (drt) and especially dopamine agonists (da). |
2024-02-23 |
2024-02-25 |
Not clear |
| Hyun Jun Lee, Darlene Mae Ortiz, Leandro Val Sayson, Mikyung Kim, Jae Hoon Cheong, Hee Jin Ki. Ameliorating effects of Acanthopanax koreanum extract and components on nicotine dependence and withdrawal symptoms. Addiction biology. vol 29. issue 2. 2024-02-21. PMID:38380695. |
in addition, alterations in the dopaminergic and drd1-epac-erk-creb pathways were observed using dopamine elisa and western blotting using mouse brains. |
2024-02-21 |
2024-02-23 |
mouse |
| Hadeel Khamis, Ohad Cohe. Coupled action potential and calcium dynamics underlie robust spontaneous firing in dopaminergic neurons. Physical biology. 2024-02-21. PMID:38382117. |
dopaminergic neurons are specialized cells in the substantia nigra, tasked with dopamine secretion. |
2024-02-21 |
2024-02-24 |
Not clear |