| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eiman Mee. Role of Noncoding RNAs in Modulating Microglial Phenotype. Global medical genetics. vol 11. issue 4. 2024-09-11. PMID:39258255. |
microglia are immunocompetent cells that are present in the retina and central nervous system, and are involved in the development maintenance and immune functions in these systems. |
2024-09-11 |
2024-09-13 |
Not clear |
| Eiman Mee. Role of Noncoding RNAs in Modulating Microglial Phenotype. Global medical genetics. vol 11. issue 4. 2024-09-11. PMID:39258255. |
microglia are also present in close association with resident cells in the retina where they engage in synapse formation, support normal functions, as well as immune defense. |
2024-09-11 |
2024-09-13 |
Not clear |
| German Cuevas-Rios, Tawfik Abou Assale, Jannis Wissfeld, Annemarie Bungartz, Julia Hofmann, Thomas Langmann, Harald Neuman. Decreased sialylation elicits complement-related microglia response and bipolar cell loss in the mouse retina. Glia. 2024-09-04. PMID:39228105. |
decreased sialylation elicits complement-related microglia response and bipolar cell loss in the mouse retina. |
2024-09-04 |
2024-09-06 |
mouse |
| Ping Song, Dhwani Parsana, Rupesh Singh, Lana M Pollock, Bela Anand-Apte, Brian D Perkin. Photoreceptor regeneration occurs normally in microglia-deficient irf8 mutant zebrafish following acute retinal damage. Scientific reports. vol 14. issue 1. 2024-08-29. PMID:39209978. |
microglia are resident immune cells in the central nervous system, including the retina that surveil the environment for damage and infection. |
2024-08-29 |
2024-09-04 |
zebrafish |
| Katerina Palacka, Barbora Hermankova, Tereza Cervena, Pavel Rossner, Alena Zajicova, Eva Uherkova, Vladimir Holan, Eliska Javorkov. The Immunomodulatory Effect of Silver Nanoparticles in a Retinal Inflammatory Environment. Inflammation. 2024-08-27. PMID:39190103. |
these data indicate that agnps regulate reactivity of activated microglia in the diseased retina and thus could provide a beneficial effect for the treatment of several retinal diseases. |
2024-08-27 |
2024-08-30 |
mouse |
| Yuxin Hu, Zhen Li, Hongxue Li, Qian Xu, Chengye Xu, Wenjian Lin, Xuefei Ma, Ming Hao, Hongyu Kuan. Severe hypoglycaemia-induced microglial inflammation damages microvascular endothelial cells, leading to retinal destruction. Diabetes & vascular disease research. vol 21. issue 4. 2024-08-26. PMID:39187253. |
human microglia (hmc) are stress-induced inflammatory cells of the retina. |
2024-08-26 |
2024-08-30 |
human |
| Lingli Zhou, Zhenhua Xu, Haining Lu, Hongkwan Cho, Yangyiran Xie, Grace Lee, Kaoru Ri, Elia J Du. Suppression of inner blood-retinal barrier breakdown and pathogenic Müller glia activation in ischemia retinopathy by myeloid cell depletion. Journal of neuroinflammation. vol 21. issue 1. 2024-08-24. PMID:39182142. |
under non-ir conditions, plx treatment successfully depleted microglia in the retina. |
2024-08-24 |
2024-08-28 |
Not clear |
| Jia Xu, Si-Jian Yu, Zi-Bing Ji. Assembling Retinal Organoids with Microglia. Journal of visualized experiments : JoVE. issue 209. 2024-08-14. PMID:39141532. |
microglia (mg) are unique resident macrophages in the retina and central nervous system (cns), serving crucial immunity functions. |
2024-08-14 |
2024-08-17 |
human |
| Francisco Martín-Loro, Fátima Cano-Cano, María J Ortega, Belén Cuevas, Laura Gómez-Jaramillo, María Del Carmen González-Montelongo, Jan Cedric Freisenhausen, Almudena Lara-Barea, Antonio Campos-Caro, Eva Zubía, Manuel Aguilar-Diosdado, Ana I Arrob. Arylphthalide Delays Diabetic Retinopathy via Immunomodulating the Early Inflammatory Response in an Animal Model of Type 1 Diabetes Mellitus. International journal of molecular sciences. vol 25. issue 15. 2024-08-10. PMID:39126007. |
specifically, type 1 diabetes mellitus (t1d) has an immune component that may determine the evolution of dr by compromising the immune response of the retina, which is mediated by microglia. |
2024-08-10 |
2024-08-13 |
rat |
| Giulia Midena, Luca Danieli, Elisabetta Pilotto, Luisa Frizziero, Edoardo Miden. Hyperreflective choroidal foci in diabetic eyes with and without macular edema: novel insights on diabetic choroidopathy. Experimental eye research. 2024-08-09. PMID:39122104. |
these hcf may represent, as in the retina, a sign of infiltration of inflammatory cells (mainly migrating microglia) into the choroid, according to the hypothesis raised by jerry lutty. |
2024-08-09 |
2024-08-13 |
human |
| Chunge Ren, Min Chen, Bangqi Ren, Yuxiao Zeng, Qiang Tan, Qiyou Li, Xue Zhang, Yajie Fang, Yixiao Zhou, Weitao Zhang, Fang Chen, Baishijiao Bian, Yong Li. Mesenchymal stem cell-derived small extracellular vesicles enhance the therapeutic effect of retinal progenitor cells in retinal degenerative disease rats. Neural regeneration research. 2024-08-05. PMID:39101643. |
concurrently, these small extracellular vesicles inhibited the activation of regional microglia, promoted the migration of transplanted retinal progenitor cells to the inner nuclear layer of the retina, and facilitated their differentiation into photoreceptors and bipolar cells. |
2024-08-05 |
2024-08-07 |
human |
| Yumei Cao, Lei Qiao, Yingying Song, Yuanye Yan, Yewen Ni, Huiyu Xi, Jiayu Chen, Suyan Li, Haiyang Li. Caspase-1 Inhibition Ameliorates Photoreceptor Damage Following Retinal Detachment by Inhibiting Microglial Pyroptosis. The American journal of pathology. 2024-07-20. PMID:39032599. |
microglia that reside in retina are activated after rd and are involved in the death of photoreceptor cells. |
2024-07-20 |
2024-07-24 |
rat |
| Stephen H Sinclair, Elan Miller, Kiran S Talekar, Stanley S Schwart. Diabetes mellitus associated neurovascular lesions in the retina and brain: A review. Frontiers in ophthalmology. vol 2. 2024-07-10. PMID:38983558. |
specifically, within the retina, and similarly within the brain cortex, lesions occur of the "neurovascular unit", comprised of focal microvascular occlusions, inflammatory endothelial and pericyte injury, with small vessel leakage resulting in injury to astrocytes, müller cells, and microglia, all of which occur with progressive neuronal apoptosis. |
2024-07-10 |
2024-07-12 |
Not clear |
| Nathaniel Ghena, Sarah R Anderson, Jacqueline M Roberts, Emmalyn Irvin, Joon Schwakopf, Alejandra Bosco, Monica L Vette. CD11c-expressing microglia are transient, driven by interactions with apoptotic cells. bioRxiv : the preprint server for biology. 2024-07-09. PMID:38979153. |
in the developing retina, we previously found a significant proportion of microglia express cd11c (integrin αx, complement receptor 4, |
2024-07-09 |
2024-07-12 |
Not clear |
| Alfred Yu, Li Xuan Tan, Aparna Lakkaraju, Luca Della Santina, Yvonne O. Microglia target synaptic sites early during excitatory circuit disassembly in neurodegeneration. bioRxiv : the preprint server for biology. 2024-06-25. PMID:38915631. |
here we analyzed the role of microglia in the synapse disassembly of degenerating postsynaptic neurons in the inner retina. |
2024-06-25 |
2024-06-27 |
Not clear |
| Philipp Dörschmann, Florentine Hunger, Hannah Schroth, Sibei Chen, Georg Kopplin, Johann Roider, Alexa Klettne. Effects of Fucoidans on Activated Retinal Microglia. International journal of molecular sciences. vol 25. issue 11. 2024-06-19. PMID:38892206. |
in this study, we tested the effects of different fucoidans (and of fucoidan-treated rpe cells) on retinal microglia to investigate whether its anti-inflammatory effect can be extrapolated to the innate immune cells of the retina. |
2024-06-19 |
2024-06-21 |
Not clear |
| Veronica Carnicelli, Noemi De Dominicis, Lucia Scipioni, Marina Fava, Federico Fanti, Benedetta Cinque, Alessandro Leuti, Clotilde Beatrice Angelucci, Anna Rita Lizzi, Roberto Giacominelli-Stuffler, Vincenzo Flati, Manuel Sergi, Dario Compagnone, Anna Maria Sardanelli, Annamaria Tisi, Sergio Oddi, Mauro Maccarron. Protective effects of fatty acid amide hydrolase inhibition in UVB-activated microglia. Biochimica et biophysica acta. Molecular and cell biology of lipids. 2024-06-10. PMID:38857757. |
in this study, we interrogated for the first time the impact of the signaling of these bioactive lipids on microglial cell responses to a sub-lethal acute uvb radiation, a physical stressor responsible of microglia reactivity in either the retina or the brain. |
2024-06-10 |
2024-06-14 |
mouse |
| Xiyu Wu, Haoxian Zhu, Junbin Liu, Shuyi Ouyang, Zheng Lyu, Yeanqi Jin, Xinyu Chen, Qianli Men. Jagged1-Notch1 Signaling Pathway Induces M1 Microglia to Disrupt the Barrier Function of Retinal Microvascular Endothelial Cells. Current eye research. 2024-05-24. PMID:38783634. |
the primary objective of this research was to investigate the impact and mechanism of m1 phenotype microglia on the barrier function of retina microvascular endothelial cells. |
2024-05-24 |
2024-05-27 |
Not clear |
| Alexander P Young, Anna-Maria Szczesniak, Karolynn Hsu, Melanie E M Kelly, Eileen M Denovan-Wrigh. Enantiomeric Agonists of the Type 2 Cannabinoid Receptor Reduce Retinal Damage during Proliferative Vitreoretinopathy and Inhibit Hyperactive Microglia ACS pharmacology & translational science. vol 7. issue 5. 2024-05-17. PMID:38751621. |
enantiomeric agonists of the type 2 cannabinoid receptor reduce retinal damage during proliferative vitreoretinopathy and inhibit hyperactive microglia microglia are resident immune cells of the central nervous system (cns) and propagate inflammation following damage to the cns, including the retina. |
2024-05-17 |
2024-05-27 |
Not clear |
| Daijin Li, Jie Chang, Yujue Wang, Xiaoye Du, Jing Xu, Jingang Cui, Teng Zhang, Yu Che. Hyperoside mitigates photoreceptor degeneration in part by targeting cGAS and suppressing DNA-induced microglial activation. Acta neuropathologica communications. vol 12. issue 1. 2024-05-17. PMID:38755736. |
activated microglia play an important role in driving photoreceptor degeneration-associated neuroinflammation in the retina. |
2024-05-17 |
2024-05-27 |
Not clear |