| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rawand H Al-Dmour, Nafe M Al-Tawarah, Nesrin Mwafi, Banan A Alkhataybeh, Khalid M Khleifat, Amjad Tarawneh, Anas O M Satari, Sahem M Alkharabsheh, Laila Albustanj. Enhancement of hippocampal-dependent spatial memory by Ashwagandha ( The International journal of neuroscience. 2023-09-02. PMID:37659008. |
we found that the rats in the nootropic groups showed significantly enhanced nootropic activity characterized by improved hippocampal-dependent spatial memory, as well as increases in the level of nmdar in the cornu ammonis 1 region of their hippocampus. |
2023-09-02 |
2023-09-07 |
rat |
| Parvaneh Mohseni-Moghaddam, Hossein Khaleghzadeh-Ahangar, Rabi Atabak. Role of Necroptosis, a Regulated Cell Death, in Seizure and Epilepsy. Neurochemical research. 2023-08-30. PMID:37646959. |
these responses involve the activation of neurons and astrocytes, consequently leading to an increase in the expression levels of proteins and genes such as rip1, rip3, and mlkl in a time-dependent manner in regions such as the hippocampus (ca1, ca3, dentate gyrus, and hilus), piriform cortex, and amygdala. |
2023-08-30 |
2023-09-07 |
Not clear |
| Liu Ruilian, Zhou Hao, Qu Honglin, Chen Yilin, Bai Qingyun, Guo Fuqiang, Wang Liang, Jiang Xiaobo, Mao Haifen. Effects of aerobic exercise on depression-like behavior and TLR4/NLRP3 pathway in hippocampus CA1 region of CUMS-depressed mice. Journal of affective disorders. 2023-08-27. PMID:37634821. |
the paper observes regulation of the expression levels of nlrp3 and tlr4 in hippocampal ca1 neurons in cums mice by aerobic exercise with constructing cums depression mouse model, in order to explore the neuroprotective mechanism of aerobic exercise on the hippocampus of depressed mice. |
2023-08-27 |
2023-09-07 |
mouse |
| Yulia V Dobryakova, Konstantin Gerasimov, Yulia S Spivak, Tinna Korotkova, Alena Koryagina, Angelina Deryabina, Vladimir A Markevich, Alexey P Bolshako. The Induction of Long-Term Potentiation by Medial Septum Activation under Urethane Anesthesia Can Alter Gene Expression in the Hippocampus. International journal of molecular sciences. vol 24. issue 16. 2023-08-26. PMID:37629149. |
we found that high-frequency stimulation (hfs) of the dmsa led to the induction of long-term potentiation in the synapses formed by the ventral hippocampal commissure on the hippocampal ca1 neurons. |
2023-08-26 |
2023-09-07 |
rat |
| Jill Rocchetti, Caroline Fasano, Gregory Dal-Bo, Elisa Guma, Salah El Mestikawy, Tak-Pan Wong, Gohar Fakhfouri, Bruno Giro. Persistent extrasynaptic hyperdopaminergia in the mouse hippocampus induces plasticity and recognition memory deficits reversed by the atypical antipsychotic sulpiride. PloS one. vol 18. issue 8. 2023-08-25. PMID:37624765. |
in vitro application of gbr on hippocampal slices abolished long-term depression (ltd) of fepsp in temporal ca1. |
2023-08-25 |
2023-09-07 |
mouse |
| Jill Rocchetti, Caroline Fasano, Gregory Dal-Bo, Elisa Guma, Salah El Mestikawy, Tak-Pan Wong, Gohar Fakhfouri, Bruno Giro. Persistent extrasynaptic hyperdopaminergia in the mouse hippocampus induces plasticity and recognition memory deficits reversed by the atypical antipsychotic sulpiride. PloS one. vol 18. issue 8. 2023-08-25. PMID:37624765. |
in conclusion, chronic dat blockade in temporal ca1 profoundly altered mesohippocampal modulation of hippocampal functions. |
2023-08-25 |
2023-09-07 |
mouse |
| Grace Minogue, Allegra Kawles, Antonia Zouridakis, Rachel Keszycki, Alyssa Macomber, Vivienne Lubbat, Nathan Gill, Qinwen Mao, Margaret E Flanagan, Hui Zhang, Rudolph Castellani, Eileen H Bigio, M-Marsel Mesulam, Changiz Geula, Tamar Gefe. Distinct Patterns of Hippocampal Pathology in Alzheimer's Disease with TDP-43. Annals of neurology. 2023-08-18. PMID:37592884. |
here, we investigated neuronal integrity and pathologic burden of tdp-43 and tau along the well-charted trisynaptic hippocampal circuit [dentate gyrus (dg), ca3, and ca1] in participants with amnestic dementia due to ad/tdp, amnestic dementia due to ad alone, or non-amnestic dementia due to tdp-43 proteinopathy associated with frontotemporal lobar degeneration (ftld-tdp). |
2023-08-18 |
2023-09-07 |
human |
| Xue Wang, Ya-Jin Shi, Ting-Yuan Niu, Ting-Ting Chen, Han-Bing Li, Su-Hui Wu, Gen-Lin L. Neuroprotective effect of 20 (S) - Protopanaxadiol (PPD) attenuates NLRP3 inflammasome-mediated microglial pyroptosis in vascular dementia rats. Neuroscience letters. 2023-08-14. PMID:37579868. |
ppd significantly reduced the cerebral infarction area and the activation of microglia in the cortex and hippocampal dg, ca1, and ca3 area. |
2023-08-14 |
2023-09-07 |
rat |
| Xue Wang, Ya-Jin Shi, Ting-Yuan Niu, Ting-Ting Chen, Han-Bing Li, Su-Hui Wu, Gen-Lin L. Neuroprotective effect of 20 (S) - Protopanaxadiol (PPD) attenuates NLRP3 inflammasome-mediated microglial pyroptosis in vascular dementia rats. Neuroscience letters. 2023-08-14. PMID:37579868. |
ppd also significantly alleviated the neurotoxicity by decreasing the aβ and p-tau in hippocampal dg, ca1, and ca3 areas. |
2023-08-14 |
2023-09-07 |
rat |
| Hongmei Wu, Dongyu Min, Buxun Sun, Yifan Ma, Hongpeng Chen, Jing Wu, Ping Ren, Jiabi Wu, Yonggang Cao, Baoshan Zhao, Peng Wan. Effect of WiFi signal exposure in utero and early life on neurodevelopment and behaviors of rats. Environmental science and pollution research international. 2023-08-10. PMID:37561300. |
the results showed that wifi signal exposure in utero and early life (1) increased the body weight of wifi + m (wifi + male) group; (2) no change in neuro-behavioral development was observed in wifi group; (3) increased learning and memory function in wifi + m group; (4) enhanced comparative levels of bdnf and p-creb proteins in the hippocampus of wifi + m group; (5) no neuronal loss or degeneration was detected, and neuronal numbers in hippocampal ca1 were no evidently differences in each group; (6) no change in the apoptosis-related proteins (caspase-3 and bax) levels; and (7) no difference in gsh-px and sod activities in the hippocampus. |
2023-08-10 |
2023-08-16 |
rat |
| Sophia Vinci-Booher, Margaret L Schlichting, Alison R Preston, Franco Pestill. Development of human hippocampal subfield microstructure and relation to associative inference. Cerebral cortex (New York, N.Y. : 1991). 2023-08-09. PMID:37557916. |
while the subiculum (sub) displayed a linear relationship with age, the dentate gyrus (dg), cornu ammonis field 1 (ca1), and cornu ammonis subfields 2 and 3 (combined; ca2/3) displayed nonlinear trajectories that interacted with sex in ca2/3. |
2023-08-09 |
2023-08-16 |
human |
| Elena A Filimonova, Anton A Pashkov, Galina I Moysak, Anastasia Y Tropynina, Svetlana Y Zhanaeva, Anna A Shvaikovskaya, Anna A Akopyan, Konstantin V Danilenko, Lyubomir I Aftanas, Maria A Tikhonova, Jamil A Rzae. Brain but not serum BDNF levels are associated with structural alterations in the hippocampal regions in patients with drug-resistant mesial temporal lobe epilepsy. Frontiers in neuroscience. vol 17. 2023-08-04. PMID:37539386. |
we found that hippocampal (but not serum) bdnf levels were negatively correlated with the contralateral volumes of the ca1 and ca4 subfields, presubiculum, subiculum, dentate gyrus, and molecular layer of the hippocampus. |
2023-08-04 |
2023-08-14 |
human |
| Maya Geva-Sagiv, Halle R Dimsdale-Zucker, Ashley B Williams, Charan Ranganat. Proximity to boundaries reveals spatial context representation in human hippocampal CA1. Neuropsychologia. 2023-08-04. PMID:37541615. |
our results highlight the privileged role of boundaries in ca1 and suggest more generally a close relationship between memory for spatial contexts and representations in the hippocampus and parahippocampal region. |
2023-08-04 |
2023-08-14 |
human |
| Mohammed H Sarikahya, Samantha L Cousineau, Marta De Felice, Hanna J Szkudlarek, Karen K W Wong, Marieka V DeVuono, Kendrick Lee, Mar Rodríguez-Ruiz, Dana Gummerson, Emma Proud, Tsun Hay Jason Ng, Roger Hudson, Tony Jung, Daniel B Hardy, Ken K-C Yeung, Susanne Schmid, Walter Rushlow, Steven R Laviolett. Prenatal THC exposure induces long-term, sex-dependent cognitive dysfunction associated with lipidomic and neuronal pathology in the prefrontal cortex-hippocampal network. Molecular psychiatry. 2023-07-31. PMID:37525013. |
lastly, using matrix-assisted laser desorption/ionization imaging mass spectrometry (maldi ims), we identified region-, age-, and sex-specific deficiencies in specific neural pufas, namely docosahexaenoic acid (dha) and arachidonic acid (ara), and related metabolites, in the pfc and hippocampus (ventral/dorsal subiculum, and ca1 regions). |
2023-07-31 |
2023-08-14 |
Not clear |
| Roy A M Haast, Sriranga Kashyap, Dimo Ivanov, Mohamed D Yousif, Jordan DeKraker, Benedikt A Poser, Ali R Kha. Novel insights into hippocampal perfusion using high-resolution, multi-modal 7T MRI. bioRxiv : the preprint server for biology. 2023-07-28. PMID:37503042. |
using high-resolution 7 tesla arterial spin labelling data, we generated robust perfusion maps and observed significant variations in perfusion among hippocampal subfields, with ca1 exhibiting the lowest perfusion levels. |
2023-07-28 |
2023-08-14 |
human |
| Gila Pirzad Jahromi, Zohreh Jangravi, Mohammadmehdi Hadipour, Hossein Shirvani, Mohammad Reza Afarinesh, Gholam Hossein Meftah. Comparative effects of the alcoholic extract of Terminalia chebula and crocin on stress‑induced anxiety‑like behavior and memory impairment in male rats. Acta neurobiologiae experimentalis. vol 83. issue 2. 2023-07-26. PMID:37493534. |
in this study, we evaluated the preventive effects of crocin and alcoholic extract of the t. chebula alone and in combination to examine their efficacy against chronic restraint stress (crs)‑induced cognitive impairment, anxiety‑like behaviors, hippocampal synaptic plasticity deficit as well as neuronal arborization damage in the hippocampal ca1 neurons. |
2023-07-26 |
2023-08-14 |
rat |
| Liming Dong, Ning Jiang, Jie Bai, Yiman Li, Zhihui Song, Xinmin Liu, Chao Zhan. Neuroprotective Effects of Dammarane Sapogenins Against lipopolysaccharide-induced Cognitive Impairment, Neuroinflammation and Synaptic Dysfunction. Neurochemical research. 2023-07-25. PMID:37490197. |
ds also remarkably inhibited lps-induced neuroinflammation by suppressing microglia overactivation, pro-inflammatory cytok ine release (tnf-α and il-1β) and reducing neuronal loss in the ca1 and dg regions of the hippocampus. |
2023-07-25 |
2023-08-14 |
rat |
| Tomas Ondrejcak, Igor Klyubin, Neng-Wei Hu, Tiernan T O'Malley, Grant T Corbett, Róisín Winters, Michael S Perkinton, Andrew Billinton, Jack A Prenderville, Dominic M Walsh, Michael J Rowa. Tau and Aß in patient-derived aqueous brain extracts act concomitantly to disrupt LTP The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-07-25. PMID:37491315. |
here, we explore how intracerebral injection of aß and tau present in such aqueous extracts of patient brain contribute to disruption of synaptic plasticity in the ca1 area of the male rat hippocampus. |
2023-07-25 |
2023-08-14 |
rat |
| Gleice K Silva-Cardoso, Willian Lazarini-Lopes, Eduardo Octaviano Primini, Jaime E Hallak, José A Crippa, Antônio W Zuardi, Norberto Garcia-Cairasco, Christie R A Leite-Paniss. Cannabidiol modulates chronic neuropathic pain aversion behavior by attenuation of neuroinflammation markers and neuronal activity in the corticolimbic circuit in male Wistar rats. Behavioural brain research. 2023-07-20. PMID:37474023. |
in cci animals, cbd was able to attenuate the increase in neuronal hyperactivity, measured by fosb protein expression, in the regions of the corticolimbic circuit: anterior cingulate cortex (acc), complex basolateral amygdala (bla), granular layer of the dentate gyrus (grdg), and dorsal hippocampus (dh) - adjacent to subiculum (ca1). |
2023-07-20 |
2023-08-14 |
rat |
| Zahra Bahari, Zohreh Jangravi, Boshra Hatef, Habib Valipour, Gholam Hossein Meftah. Creatine supplementation protects spatial memory and long-term potentiation against chronic restraint stress. Behavioural pharmacology. 2023-07-18. PMID:37462147. |
hence, in this study, we examined the effects of creatine supplementation on memory, synaptic plasticity, and neuronal arborization in the ca1 region of the hippocampus in rats under chronic restraint stress (crs). |
2023-07-18 |
2023-08-14 |
rat |