| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gonzalo Ugarte, Ricardo Piña, Darwin Contreras, Felipe Godoy, David Rubio, Carlos Rozas, Marc Zeise, Rodrigo Vidal, Jorge Escobar, Bernardo Morale. Attention Deficit-Hyperactivity Disorder (ADHD): From Abnormal Behavior to Impairment in Synaptic Plasticity. Biology. vol 12. issue 9. 2023-09-28. PMID:37759640. |
using a murine model of adhd, a delay in dendritic spines' maturation in ca1 hippocampal neurons correlated with impaired working memory and hippocampal ltp has recently reported. |
2023-09-28 |
2023-10-07 |
Not clear |
| Mihai Ceanga, Vahid Rahmati, Holger Haselmann, Lars Schmidl, Daniel Hunter, Anna-Katherina Brauer, Sabine Liebscher, Jakob Kreye, Harald Prüss, Laurent Groc, Stefan Hallermann, Josep Dalmau, Alessandro Ori, Manfred Heckmann, Christian Gei. Human NMDAR autoantibodies disrupt excitatory-inhibitory balance, leading to hippocampal network hypersynchrony. Cell reports. vol 42. issue 10. 2023-09-28. PMID:37768823. |
after passive transfer of patients' cerebrospinal fluid or human monoclonal anti-glun1-autoantibodies in mice, we find a disrupted excitatory-inhibitory balance resulting from ca1 neuronal hypoexcitability, reduced ampa receptor (ampar) signaling, and faster synaptic inhibition in acute hippocampal slices. |
2023-09-28 |
2023-10-07 |
mouse |
| Courtney Cross, Maya Davies, Emma Bateman, Elise Crame, Paul Joyce, Anthony Wignall, Amin Ariaee, Marc Gladman, Hannah Wardill, Joanne M Bowe. Fibre-rich diet attenuates chemotherapy-related neuroinflammation in mice. Brain, behavior, and immunity. 2023-09-27. PMID:37757978. |
in the context of 5-fu, the diet reduced gfap expression in the ca1 region of the hippocampus (p < 0.0001) as well as the midbrain (p = 0.0216). |
2023-09-27 |
2023-10-07 |
mouse |
| Asim J Rashid, Ali Golbabaei, Sheena A Jossely. Memory: Meet the new engram, same as the old engram. Current biology : CB. vol 33. issue 18. 2023-09-26. PMID:37751708. |
a new study shows that while the neuronal organization of a memory changes with time, including greater cortical engagement, a core ensemble exists in the ca1 region of the dorsal hippocampus that is necessary for retrieval of both a recent and remote memory. |
2023-09-26 |
2023-10-07 |
Not clear |
| Stanislava Bukatova, Alexandra Reichova, Zuzana Bacova, Jan Bako. Neonatal oxytocin treatment alters levels of precursor and mature BDNF forms and modifies the expression of neuronal markers in the male rat hippocampus. Neuropeptides. vol 102. 2023-09-23. PMID:37741113. |
we found that after oxytocin administration, levels of probdnf increased on p5 and mbdnf on p7 in the ca1 hippocampal region. |
2023-09-23 |
2023-10-07 |
rat |
| Wei-Hong Xiong, Maozhen Qin, Haining Zhon. PKA catalytic subunits dissociate from regulatory subunits to regulate neuronal functions. bioRxiv : the preprint server for biology. 2023-09-21. PMID:37732264. |
here we report that different pka subtypes, as defined by the regulatory subunit, exhibit distinct subcellular localization at rest in ca1 neurons of cultured hippocampal slices. |
2023-09-21 |
2023-10-07 |
Not clear |
| Eduarda G Nachtigall, Jociane de C Myskiw, Ivan Izquierdo, Cristiane R G Furin. Cellular mechanisms of contextual fear memory reconsolidation: Role of hippocampal SFKs, TrkB receptors and GluN2B-containing NMDA receptors. Psychopharmacology. 2023-09-12. PMID:37700085. |
we demonstrated that the blockade of src family kinases (sfks), glun2b-containing nmda receptors and trkb receptors (trkbr) in the ca1 region of the hippocampus immediately after the reactivation session impaired contextual fear memory reconsolidation. |
2023-09-12 |
2023-10-07 |
rat |
| Ruiyi Chen, Yash S Vakilna, Samuel Brandon Lassers, William C Tang, Gregory J Brewe. Hippocampal network axons respond to patterned theta burst stimulation with lower activity of initially higher spike train similarity from EC to DG and later similarity of axons from CA1 to EC. Journal of neural engineering. 2023-09-04. PMID:37666242. |
hippocampal network axons respond to patterned theta burst stimulation with lower activity of initially higher spike train similarity from ec to dg and later similarity of axons from ca1 to ec. |
2023-09-04 |
2023-09-07 |
Not clear |
| Rawand H Al-Dmour, Nafe M Al-Tawarah, Nesrin Mwafi, Banan A Alkhataybeh, Khalid M Khleifat, Amjad Tarawneh, Anas O M Satari, Sahem M Alkharabsheh, Laila Albustanj. Enhancement of hippocampal-dependent spatial memory by Ashwagandha ( The International journal of neuroscience. 2023-09-02. PMID:37659008. |
we found that the rats in the nootropic groups showed significantly enhanced nootropic activity characterized by improved hippocampal-dependent spatial memory, as well as increases in the level of nmdar in the cornu ammonis 1 region of their hippocampus. |
2023-09-02 |
2023-09-07 |
rat |
| Parvaneh Mohseni-Moghaddam, Hossein Khaleghzadeh-Ahangar, Rabi Atabak. Role of Necroptosis, a Regulated Cell Death, in Seizure and Epilepsy. Neurochemical research. 2023-08-30. PMID:37646959. |
these responses involve the activation of neurons and astrocytes, consequently leading to an increase in the expression levels of proteins and genes such as rip1, rip3, and mlkl in a time-dependent manner in regions such as the hippocampus (ca1, ca3, dentate gyrus, and hilus), piriform cortex, and amygdala. |
2023-08-30 |
2023-09-07 |
Not clear |
| Liu Ruilian, Zhou Hao, Qu Honglin, Chen Yilin, Bai Qingyun, Guo Fuqiang, Wang Liang, Jiang Xiaobo, Mao Haifen. Effects of aerobic exercise on depression-like behavior and TLR4/NLRP3 pathway in hippocampus CA1 region of CUMS-depressed mice. Journal of affective disorders. 2023-08-27. PMID:37634821. |
the paper observes regulation of the expression levels of nlrp3 and tlr4 in hippocampal ca1 neurons in cums mice by aerobic exercise with constructing cums depression mouse model, in order to explore the neuroprotective mechanism of aerobic exercise on the hippocampus of depressed mice. |
2023-08-27 |
2023-09-07 |
mouse |
| Yulia V Dobryakova, Konstantin Gerasimov, Yulia S Spivak, Tinna Korotkova, Alena Koryagina, Angelina Deryabina, Vladimir A Markevich, Alexey P Bolshako. The Induction of Long-Term Potentiation by Medial Septum Activation under Urethane Anesthesia Can Alter Gene Expression in the Hippocampus. International journal of molecular sciences. vol 24. issue 16. 2023-08-26. PMID:37629149. |
we found that high-frequency stimulation (hfs) of the dmsa led to the induction of long-term potentiation in the synapses formed by the ventral hippocampal commissure on the hippocampal ca1 neurons. |
2023-08-26 |
2023-09-07 |
rat |
| Jill Rocchetti, Caroline Fasano, Gregory Dal-Bo, Elisa Guma, Salah El Mestikawy, Tak-Pan Wong, Gohar Fakhfouri, Bruno Giro. Persistent extrasynaptic hyperdopaminergia in the mouse hippocampus induces plasticity and recognition memory deficits reversed by the atypical antipsychotic sulpiride. PloS one. vol 18. issue 8. 2023-08-25. PMID:37624765. |
in vitro application of gbr on hippocampal slices abolished long-term depression (ltd) of fepsp in temporal ca1. |
2023-08-25 |
2023-09-07 |
mouse |
| Jill Rocchetti, Caroline Fasano, Gregory Dal-Bo, Elisa Guma, Salah El Mestikawy, Tak-Pan Wong, Gohar Fakhfouri, Bruno Giro. Persistent extrasynaptic hyperdopaminergia in the mouse hippocampus induces plasticity and recognition memory deficits reversed by the atypical antipsychotic sulpiride. PloS one. vol 18. issue 8. 2023-08-25. PMID:37624765. |
in conclusion, chronic dat blockade in temporal ca1 profoundly altered mesohippocampal modulation of hippocampal functions. |
2023-08-25 |
2023-09-07 |
mouse |
| Grace Minogue, Allegra Kawles, Antonia Zouridakis, Rachel Keszycki, Alyssa Macomber, Vivienne Lubbat, Nathan Gill, Qinwen Mao, Margaret E Flanagan, Hui Zhang, Rudolph Castellani, Eileen H Bigio, M-Marsel Mesulam, Changiz Geula, Tamar Gefe. Distinct Patterns of Hippocampal Pathology in Alzheimer's Disease with TDP-43. Annals of neurology. 2023-08-18. PMID:37592884. |
here, we investigated neuronal integrity and pathologic burden of tdp-43 and tau along the well-charted trisynaptic hippocampal circuit [dentate gyrus (dg), ca3, and ca1] in participants with amnestic dementia due to ad/tdp, amnestic dementia due to ad alone, or non-amnestic dementia due to tdp-43 proteinopathy associated with frontotemporal lobar degeneration (ftld-tdp). |
2023-08-18 |
2023-09-07 |
human |
| Xue Wang, Ya-Jin Shi, Ting-Yuan Niu, Ting-Ting Chen, Han-Bing Li, Su-Hui Wu, Gen-Lin L. Neuroprotective effect of 20 (S) - Protopanaxadiol (PPD) attenuates NLRP3 inflammasome-mediated microglial pyroptosis in vascular dementia rats. Neuroscience letters. 2023-08-14. PMID:37579868. |
ppd significantly reduced the cerebral infarction area and the activation of microglia in the cortex and hippocampal dg, ca1, and ca3 area. |
2023-08-14 |
2023-09-07 |
rat |
| Xue Wang, Ya-Jin Shi, Ting-Yuan Niu, Ting-Ting Chen, Han-Bing Li, Su-Hui Wu, Gen-Lin L. Neuroprotective effect of 20 (S) - Protopanaxadiol (PPD) attenuates NLRP3 inflammasome-mediated microglial pyroptosis in vascular dementia rats. Neuroscience letters. 2023-08-14. PMID:37579868. |
ppd also significantly alleviated the neurotoxicity by decreasing the aβ and p-tau in hippocampal dg, ca1, and ca3 areas. |
2023-08-14 |
2023-09-07 |
rat |
| Hongmei Wu, Dongyu Min, Buxun Sun, Yifan Ma, Hongpeng Chen, Jing Wu, Ping Ren, Jiabi Wu, Yonggang Cao, Baoshan Zhao, Peng Wan. Effect of WiFi signal exposure in utero and early life on neurodevelopment and behaviors of rats. Environmental science and pollution research international. 2023-08-10. PMID:37561300. |
the results showed that wifi signal exposure in utero and early life (1) increased the body weight of wifi + m (wifi + male) group; (2) no change in neuro-behavioral development was observed in wifi group; (3) increased learning and memory function in wifi + m group; (4) enhanced comparative levels of bdnf and p-creb proteins in the hippocampus of wifi + m group; (5) no neuronal loss or degeneration was detected, and neuronal numbers in hippocampal ca1 were no evidently differences in each group; (6) no change in the apoptosis-related proteins (caspase-3 and bax) levels; and (7) no difference in gsh-px and sod activities in the hippocampus. |
2023-08-10 |
2023-08-16 |
rat |
| Sophia Vinci-Booher, Margaret L Schlichting, Alison R Preston, Franco Pestill. Development of human hippocampal subfield microstructure and relation to associative inference. Cerebral cortex (New York, N.Y. : 1991). 2023-08-09. PMID:37557916. |
while the subiculum (sub) displayed a linear relationship with age, the dentate gyrus (dg), cornu ammonis field 1 (ca1), and cornu ammonis subfields 2 and 3 (combined; ca2/3) displayed nonlinear trajectories that interacted with sex in ca2/3. |
2023-08-09 |
2023-08-16 |
human |
| Elena A Filimonova, Anton A Pashkov, Galina I Moysak, Anastasia Y Tropynina, Svetlana Y Zhanaeva, Anna A Shvaikovskaya, Anna A Akopyan, Konstantin V Danilenko, Lyubomir I Aftanas, Maria A Tikhonova, Jamil A Rzae. Brain but not serum BDNF levels are associated with structural alterations in the hippocampal regions in patients with drug-resistant mesial temporal lobe epilepsy. Frontiers in neuroscience. vol 17. 2023-08-04. PMID:37539386. |
we found that hippocampal (but not serum) bdnf levels were negatively correlated with the contralateral volumes of the ca1 and ca4 subfields, presubiculum, subiculum, dentate gyrus, and molecular layer of the hippocampus. |
2023-08-04 |
2023-08-14 |
human |