| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Annalisa Adinolfi, Gabriele Di Sante, Luca Rivignani Vaccari, Maria Tredicine, Francesco Ria, Davide Bonvissuto, Valentina Corvino, Claudio Sette, Maria Concetta Gelos. Regionally restricted modulation of Frontiers in molecular neuroscience. vol 15. 2023-01-30. PMID:36710925. |
in this study, we investigated several parameters of neuroplasticity in the hippocampus of the experimental autoimmune encephalomyelitis (eae) sjl/j mouse model, characterized by rostral inflammatory and demyelinating lesions similar to relapsing-remitting ms. by combining morphological and molecular analyses, we found that the hippocampus undergoes extensive inflammation in eae-mice, more pronounced in the ca3 and dentate gyrus (dg) subfields than in the ca1, associated with changes in gabaergic circuitry, as indicated by the increased expression of the interneuron marker parvalbumin selectively in ca3. |
2023-01-30 |
2023-08-14 |
mouse |
| Yann Vanrobeys, Utsav Mukherjee, Lucy Langmack, Ethan Bahl, Li-Chun Lin, Jacob J Michaelson, Ted Abel, Snehajyoti Chatterje. Mapping the spatial transcriptomic signature of the hippocampus during memory consolidation. bioRxiv : the preprint server for biology. 2023-01-30. PMID:36711475. |
we demonstrate the functional relevance of subregion-specific gene expression by genetic manipulation of a transcription factor selectively in the ca1 hippocampal subregion, leading to long-term memory deficits. |
2023-01-30 |
2023-08-14 |
Not clear |
| Price Obot, Galadu Subah, Antonia Schonwald, Jian Pan, Libor Velíšek, Jana Velíšková, Patric K Stanton, Eliana Sceme. Astrocyte and neuronal Panx1 support long-term reference memory in mice. bioRxiv : the preprint server for biology. 2023-01-30. PMID:36711845. |
field potential recordings in hippocampal slices of panx1-null mice revealed an attenuation of both long-term potentiation (ltp) of synaptic strength and long-term depression (ltd) at schaffer collateral - ca1 synapses without alterations basal synaptic transmission or pre-synaptic paired-pulse facilitation. |
2023-01-30 |
2023-08-14 |
mouse |
| Iván Ballasch, Esther García-García, Cristina Vila, Anna Pérez-González, Anna Sancho-Balsells, Jéssica Fernández, David Soto, Mar Puigdellívol, Xavier Gasull, Jordi Alberch, Manuel J Rodríguez, Josep M Canals, Albert Giral. Ikzf1 as a novel regulator of microglial homeostasis in inflammation and neurodegeneration. Brain, behavior, and immunity. 2023-01-26. PMID:36702234. |
by characterizing the ikzf1 deficient mice, we observed that these mice displayed spatial learning deficits, impaired hippocampal ca3-ca1 long-term potentiation, and decreased spine density in pyramidal neurons of the ca1, which correlates with an increased expression of synaptic markers within microglia. |
2023-01-26 |
2023-08-14 |
mouse |
| Valentina Licheri, Giuseppe Talani, Giovanni Biggio, Enrico Sann. Bi-directional modulation of hyperpolarization-activated cation currents (I Neuropharmacology. 2023-01-23. PMID:36690323. |
previous work has demonstrated that etoh enhances the firing rate of hippocampal gabaergic interneurons and thus the presynaptic gaba release at ca1 and ca3 inhibitory synapses through a positive modulation of the hyperpolarization-activated cyclic nucleotide-gated cation (hcn) channels. |
2023-01-23 |
2023-08-14 |
Not clear |
| Naserddine Hamadi, Ömür Gülsüm Deniz, Ahlam Said Abi Issa, Azim Ullah Shamsul Islam, Naheed Amir, Saeed Tariq Minhas, Nather Madjid, Fatima Khelifi-Touhami, Süleyman Kaplan, Abdu Ade. Stereological Evidence of Non-Selective Hippocampal Neurodegeneration, IGF-1 Depletion, and Behavioral Deficit following Short Term Bilateral Adrenalectomy in Wistar Rats. Biomolecules. vol 13. issue 1. 2023-01-21. PMID:36671407. |
stereological counting in the hippocampus revealed significant neuronal deaths in the dentate gyrus and ca4/ca3, but not in the ca2 and ca1 areas, 7 and 14 days post adrenalectomy. |
2023-01-21 |
2023-08-14 |
rat |
| Nan Nan, Qi Wang, Mei-Jing Li, Yong-Song Xu, Xiao-Meng Guo, Rui Xu, Zhe Ma, Si-Hui Wang, Jing Li, Hui Zhao, Mu-Xin Gon. The Microbiota-Dependent Treatment of Wuzhuyu Decoction for Chronic Migraine Model Rat Associated with Anxiety-Depression Like Behavior. Oxidative medicine and cellular longevity. vol 2023. 2023-01-17. PMID:36647428. |
the cm rats exhibited anxiety- and depression-like behavior with 5-ht and number of neurons decreased in the ca1 and ca2 regions of hippocampal. |
2023-01-17 |
2023-08-14 |
rat |
| Amolika Dhungana, Serena Becchi, Jessica Leake, Gary Morris, Nesli Avgan, Bernard W Balleine, Bryce Vissel, Laura A Bradfiel. Goal-directed action is transiently impaired in a hAPP-J20 mouse model of Alzheimer's disease. eNeuro. 2023-01-17. PMID:36650070. |
together, these data demonstrate that goal-directed action is initially impaired in j20 mice of both sexes and in aging male mice regardless of genotype, and that this impairment is related to neuroinflammation in the dorsal ca1 hippocampal region. |
2023-01-17 |
2023-08-14 |
mouse |
| Olesia M Bilash, Spyridon Chavlis, Cara D Johnson, Panayiota Poirazi, Jayeeta Bas. Lateral entorhinal cortex inputs modulate hippocampal dendritic excitability by recruiting a local disinhibitory microcircuit. Cell reports. vol 42. issue 1. 2023-01-14. PMID:36640337. |
we combine functional circuit mapping and computational modeling to examine how long-range glutamatergic lec projections modulate compartment-specific excitation-inhibition dynamics in hippocampal area ca1. |
2023-01-14 |
2023-08-14 |
Not clear |
| Zhong Luo, Meng Xu, Linhai Zhang, Haiqing Zhang, Zucai Xu, Zhongxiang X. Glycyrrhizin regulates the HMGB1/P38MAPK signalling pathway in status epilepticus. Molecular medicine reports. vol 27. issue 2. 2023-01-12. PMID:36633134. |
furthermore, gl could alleviate neuronal injury in the ca1 region of the hippocampus and prevented hmgb1 translocation from the nucleus into the cytoplasm in these areas. |
2023-01-12 |
2023-08-14 |
rat |
| Pasha A Davoudian, Ling-Xiao Shao, Alex C Kwa. Shared and Distinct Brain Regions Targeted for Immediate Early Gene Expression by Ketamine and Psilocybin. ACS chemical neuroscience. 2023-01-11. PMID:36630309. |
select regions exhibited drug-preferential differences, such as dorsal raphe and insular cortex for psilocybin and the ca1 subfield of hippocampus for ketamine. |
2023-01-11 |
2023-08-14 |
mouse |
| Teryn D Johnson, Katherine R Keefe, Lara M Range. Stimulation-induced entrainment of hippocampal network activity: Identifying optimal input frequencies. Hippocampus. 2023-01-10. PMID:36624658. |
previously, it has been shown that the coordination of rhythmic activity between the lateral entorhinal cortex (lec) and the ca1 region of the hippocampus is tightly correlated with the onset of learning in an associative learning task. |
2023-01-10 |
2023-08-14 |
rat |
| Lívia Neves, Bruno Lobão-Soares, Ana Paula de Castro Araujo, Alan Michel Bezerra Furtunato, Izabela Paiva, Nicholy Souza, Anne Kelly Morais, George Nascimento, Elaine Gavioli, Adriano Bretanha Lopes Tort, Flávio Freitas Barbosa, Hindiael Belchio. Theta and gamma oscillations in the rat hippocampus support the discrimination of object displacement in a recognition memory task. Frontiers in behavioral neuroscience. vol 16. 2023-01-09. PMID:36620858. |
here, we chronically implanted microelectrode arrays in adult male wistar rats to record network oscillations from dg, ca3, and ca1 of the dorsal hippocampus while animals executed an object recognition task of high and low spatial displacement tests (hd: 108 cm, and ld: 54 cm, respectively). |
2023-01-09 |
2023-08-14 |
rat |
| Fengmei Wei, Wenhao Li, Bo Ma, Ziqing Yan, Zhi Wang, Lu Zhang, Donghua Xian, Yongqing He, Xiao Deng, Yajie Chen, Zheng Tingjuan, Junfeng Zhang, Yuhong Jin. Local CRF and oxytocin receptors correlate with female experience-driven avoidance change and hippocampal neuronal plasticity. Neurochemistry international. 2023-01-09. PMID:36623734. |
the study explored how neonatal maternal deprivation (md) and post-weaning environmental enrichment (ee) impacted the ca1 and dg's neuronal plasticity in the dorsal hippocampus, and its relationships with passive avoidance, local corticotrophin-releasing factor (crf) levels, and oxytocin receptor (otr) levels in female balb/c mice. |
2023-01-09 |
2023-08-14 |
mouse |
| Pei-Yi Lin, Lulu Y Chen, Man Jiang, Justin H Trotter, Erica Seigneur, Thomas C Südho. Neurexin-2: An inhibitory neurexin that restricts excitatory synapse formation in the hippocampus. Science advances. vol 9. issue 1. 2023-01-06. PMID:36608123. |
moreover, hippocampal neurexin-2 deletions also increased synaptic connectivity in the ca1 region when induced in mature mice and impaired the cognitive flexibility of spatial memory. |
2023-01-06 |
2023-08-14 |
mouse |
| Qi Liu, Zixu Wang, Jing Cao, Yulan Dong, Yaoxing Che. Insulin ameliorates dim blue light at night-induced apoptosis in hippocampal neurons via the IR/IRS1/AKT/GSK3β/β-catenin signaling pathway. Ecotoxicology and environmental safety. vol 250. 2022-12-31. PMID:36586168. |
consistent with these changes, we also observed that dlan-bl reduced the number of neurons in the ca1, ca3 and dg regions of the hippocampus, up-regulated the mrna expression levels of bax, down-regulated the mrna expression levels of bcl-2, bcl-xl and the protein expression level of pirs1, pakt, pgsk3β, β-catenin in the hippocampus. |
2022-12-31 |
2023-08-14 |
mouse |
| Janine I Rossato, Andressa Radiske, Maria Carolina Gonzalez, Lia R M Bevilaqua, Martín Cammarot. On the effect of hippocampal c-Jun N-terminal kinase inhibition on object recognition memory. Frontiers in behavioral neuroscience. vol 16. 2022-12-29. PMID:36578877. |
here we show that when injected into dorsal ca1 5 min, but not 6 h, after training adult male rats in the novel object recognition learning task, the jnk inhibitor sp600125 impaired orm for at least 7 days without affecting exploratory activity, short-term orm retention, or the functional integrity of the hippocampus. |
2022-12-29 |
2023-08-14 |
rat |
| Huanqiu Zhang, P Dylan Rich, Albert K Lee, Tatyana O Sharpe. Hippocampal spatial representations exhibit a hyperbolic geometry that expands with experience. Nature neuroscience. 2022-12-29. PMID:36581729. |
here we report that neurons in the ca1 region of rat hippocampus that mediate spatial perception represent space according to a non-linear hyperbolic geometry. |
2022-12-29 |
2023-08-14 |
rat |
| Azahara Oliva, Antonio Fernandez-Ruiz, Lindsay A Karab. CA2 orchestrates hippocampal network dynamics. Hippocampus. 2022-12-28. PMID:36575880. |
the hippocampus is composed of various subregions: ca1, ca2, ca3, and the dentate gyrus (dg). |
2022-12-28 |
2023-08-14 |
Not clear |
| Eu-Gene Kim, Wonseok Chang, SangYep Shin, Anjana Silwal Adhikari, Geun Hee Seol, Dae-Yong Song, Sun Seek Mi. Maternal separation in mice leads to anxiety-like/aggressive behavior and increases immunoreactivity for glutamic acid decarboxylase and parvalbumin in the adolescence ventral hippocampus. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 27. issue 1. 2022-12-28. PMID:36575939. |
gad67-positive neurons were increased in the hippocampal regions we observed: dentate gyrus (dg), ca3, ca1, subiculum, presubiculum, and parasubiculum. |
2022-12-28 |
2023-08-14 |
mouse |