| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Zahorodna, K Tokarski, M Bija. Repeated corticosterone administration increases excitatory effect of 5-HT4 receptor agonist in the rat hippocampus. Polish journal of pharmacology. vol 52. issue 2. 2001-02-02. PMID:10949112. |
the objective of the present study was to investigate whether repeated exposure of rats to high level of corticosterone affects responses of ca1 hippocampal cells to the 5-ht4 receptor agonist zacopride. |
2001-02-02 |
2023-08-12 |
rat |
| C G Parsons, W Danysz, G Quac. Memantine and the amino-alkyl-cyclohexane MRZ 2/579 are moderate affinity uncompetitive NMDA receptor antagonists--in vitro characterisation. Amino acids. vol 19. issue 1. 2001-02-01. PMID:11026484. |
mrz 2/579 protected cultured cortical neurones against glutamate toxicity with an ic50 of 2.16microm and was also effective in protecting hippocampal slices against hypoxia/hypoglycaemia-induced reduction of fepsp amplitude in ca1 with an ec50 of 7.01microm. |
2001-02-01 |
2023-08-12 |
Not clear |
| C Leranth, M Shanabrough, T L Horvat. Hormonal regulation of hippocampal spine synapse density involves subcortical mediation. Neuroscience. vol 101. issue 2. 2001-02-01. PMID:11074158. |
these observations indicate that fimbria/fornix transection itself does not considerably influence ca1 area pyramidal cell spine density and, most importantly, that the estrogenic effect on hippocampal morphology, in addition to directly affecting the hippocampus, involves subcortical mediation. |
2001-02-01 |
2023-08-12 |
rat |
| F G Pike, R S Goddard, J M Suckling, P Ganter, N Kasthuri, O Paulse. Distinct frequency preferences of different types of rat hippocampal neurones in response to oscillatory input currents. The Journal of physiology. vol 529 Pt 1. 2001-01-26. PMID:11080262. |
to investigate how different neuronal types within this network respond to oscillatory inputs we made whole-cell current clamp recordings from three different types of neurones in the ca1 region of rat hippocampal slices: pyramidal cells, fast-spiking interneurones and horizontal interneurones, and recorded their response to sinusoidal inputs at physiologically relevant frequencies (1-100 hz). |
2001-01-26 |
2023-08-12 |
rat |
| S S Smith, F C Hsu, X Li, C A Frye, D S Faber, R S Markowit. Oestrogen effects in olivo-cerebellar and hippocampal circuits. Novartis Foundation symposium. vol 230. 2001-01-25. PMID:10965507. |
this effect was correlated with a decrease in decay time of tetrodotoxin-resistant miniature inhibitory postsynaptic currents (mipscs) recorded from pyramidal cells in ca1 hippocampus, an effect which would tend to reduce total gaba inhibition. |
2001-01-25 |
2023-08-12 |
Not clear |
| A C Chen, A J Eisch, N Sakai, M Takahashi, E J Nestler, R S Duma. Regulation of GFRalpha-1 and GFRalpha-2 mRNAs in rat brain by electroconvulsive seizure. Synapse (New York, N.Y.). vol 39. issue 1. 2001-01-25. PMID:11071708. |
chronic (14 days) administration of different classes of antidepressant drugs, including tranylcypromine, desipramine, or fluoxetine, did not significantly affect the gdnf, gfralpha-1, gfralpha-2, or ret mrna levels in ca1, ca3, and dentate gyrus areas of hippocampus. |
2001-01-25 |
2023-08-12 |
rat |
| G L Wenk, C A Barne. Regional changes in the hippocampal density of AMPA and NMDA receptors across the lifespan of the rat. Brain research. vol 885. issue 1. 2001-01-25. PMID:11121523. |
we found an age-related decline in the number of nmda receptors in the ca1, ca3 and subicular cell regions of the hippocampus, but not in the fd/hilar region, and an age-related decline in the number of ampa receptors in the fd/hilar region, but not in the ca fields. |
2001-01-25 |
2023-08-12 |
rat |
| S Traver, C Bidot, N Spassky, T Baltauss, M F De Tand, J L Thomas, B Zalc, I Janoueix-Lerosey, J D Gunzbur. RGS14 is a novel Rap effector that preferentially regulates the GTPase activity of galphao. The Biochemical journal. vol 350 Pt 1. 2001-01-11. PMID:10926822. |
in situ hybridization studies showed that it is highly expressed only in certain areas of mouse brain (such as the ca1 and ca2 regions of the hippocampus), and that this pattern closely resembles that of rap2, but not rap1, expression. |
2001-01-11 |
2023-08-12 |
mouse |
| R A Cunha, T Almeida, J A Ribeir. Modification by arachidonic acid of extracellular adenosine metabolism and neuromodulatory action in the rat hippocampus. The Journal of biological chemistry. vol 275. issue 48. 2001-01-11. PMID:10978314. |
aa (30 microm) increased by 36-42% the tonic inhibition by endogenous extracellular adenosine of adenosine a(1) receptors in the modulation of acetylcholine release and of ca1 hippocampal synaptic transmission in hippocampal slices. |
2001-01-11 |
2023-08-12 |
rat |
| Y Izumi, A R Zarrin, C F Zorumsk. Arachidonic acid rescues hippocampal long-term potentiation blocked by group I metabotropic glutamate receptor antagonists. Neuroscience. vol 100. issue 3. 2001-01-11. PMID:11098111. |
among antagonists of group i metabotropic glutamate receptors, the mglur5-selective 6-methyl-2-(phenylethynyl)-pyridine inhibited long-term potentiation in the ca1 region of hippocampal slices from 30-day-old rats, whereas (rs)-1-aminoindan-1,5-dicarboxylic acid and cyclopropan[b]chromen-1a-carboxylic acid ethylester, which are more selective for mglur1, failed to inhibit long-term potentiation. |
2001-01-11 |
2023-08-12 |
rat |
| L Sui, D Y Ruan, S Y Ge, X M Men. Two components of long-term depression are impaired by chronic lead exposure in area CA1 and dentate gyrus of rat hippocampus in vitro. Neurotoxicology and teratology. vol 22. issue 5. 2001-01-11. PMID:11106867. |
two components of long-term depression are impaired by chronic lead exposure in area ca1 and dentate gyrus of rat hippocampus in vitro. |
2001-01-11 |
2023-08-12 |
rat |
| L Sui, D Y Ruan, S Y Ge, X M Men. Two components of long-term depression are impaired by chronic lead exposure in area CA1 and dentate gyrus of rat hippocampus in vitro. Neurotoxicology and teratology. vol 22. issue 5. 2001-01-11. PMID:11106867. |
previous studies have demonstrated that low-level lead exposure can impair the induction of long-term depression (ltd) in area ca1 and dentate gyrus (dg) of rat hippocampus in vitro and in vivo. |
2001-01-11 |
2023-08-12 |
rat |
| L Sui, D Y Ruan, S Y Ge, X M Men. Two components of long-term depression are impaired by chronic lead exposure in area CA1 and dentate gyrus of rat hippocampus in vitro. Neurotoxicology and teratology. vol 22. issue 5. 2001-01-11. PMID:11106867. |
furthermore, the impairment of two components by lead exposure might be similar in area ca1, while the impairment of vgcc-ltd might be more serious in dg of hippocampus. |
2001-01-11 |
2023-08-12 |
rat |
| N H Woo, S N Duffy, T Abel, P V Nguye. Genetic and pharmacological demonstration of differential recruitment of cAMP-dependent protein kinases by synaptic activity. Journal of neurophysiology. vol 84. issue 6. 2001-01-11. PMID:11110804. |
transgenic mice [r(ab) mice] that express an inhibitory form of a particular type of regulatory subunit of pka (type-ialpha) showed significantly reduced ltp in area ca1 of hippocampal slices as compared with slices from wild-type mice. |
2001-01-11 |
2023-08-12 |
mouse |
| M Zhou, H K Kimelber. Freshly isolated astrocytes from rat hippocampus show two distinct current patterns and different [K(+)](o) uptake capabilities. Journal of neurophysiology. vol 84. issue 6. 2001-01-11. PMID:11110805. |
in the present study, we have addressed some of these questions in glial fibrillary acidic protein [gfap(+)], freshly isolated astrocytes (fias) from ca1 and ca3 regions of p7-15 rat hippocampus. |
2001-01-11 |
2023-08-12 |
rat |
| D A Montoya, A M White, C L Williams, J K Blusztajn, W H Meck, H S Swartzwelde. Prenatal choline exposure alters hippocampal responsiveness to cholinergic stimulation in adulthood. Brain research. Developmental brain research. vol 123. issue 1. 2001-01-09. PMID:11020547. |
these results suggest that gaba receptor-mediated inhibition remains intact after prenatal choline manipulations, and that enhancement of the excitatory responsiveness of hippocampal circuits in slices from prenatally choline supplemented rats may be related in part to an increase in cholinergic tone within the ca1 circuit. |
2001-01-09 |
2023-08-12 |
rat |
| S D Norrholm, C C Ouime. Chronic fluoxetine administration to juvenile rats prevents age-associated dendritic spine proliferation in hippocampus. Brain research. vol 883. issue 2. 2001-01-09. PMID:11074049. |
in the present study, dendritic spine density was studied in the hippocampus (ca1) and dentate gyrus of juvenile rats acutely and chronically exposed to antidepressant drugs that act on serotonin and norepinephrine. |
2001-01-09 |
2023-08-12 |
rat |
| N P Staff, H Y Jung, T Thiagarajan, M Yao, N Sprusto. Resting and active properties of pyramidal neurons in subiculum and CA1 of rat hippocampus. Journal of neurophysiology. vol 84. issue 5. 2001-01-04. PMID:11067982. |
we also found that both regular spiking subicular and ca1 neurons could be transformed into a burst firing mode by application of a low concentration of 4-aminopyridine, suggesting that in both hippocampal subfields, firing properties are regulated by a slowly inactivating, d-type potassium current. |
2001-01-04 |
2023-08-12 |
rat |
| T Kikusui, A Aoyagi, T Kanek. Spatial working memory is independent of hippocampal CA1 long-term potentiation in rats. Behavioral neuroscience. vol 114. issue 4. 2001-01-02. PMID:10959528. |
these results suggest that spatial working memory is independent of hippocampal ca1 ltp and that the central cholinergic system is involved in spatial working memory, but not through the modulation of hippocampal cai ltp. |
2001-01-02 |
2023-08-12 |
rat |
| L Bjartmar, I M Johansson, J Marcusson, S B Ross, J R Seckl, T Olsso. Selective effects on NGFI-A, MR, GR and NGFI-B hippocampal mRNA expression after chronic treatment with different subclasses of antidepressants in the rat. Psychopharmacology. vol 151. issue 1. 2000-12-28. PMID:10958110. |
mr mrna expression was induced in hippocampal ca1/ca2 subregions (27-37%) by all antidepressants, while moclobemide and 8-oh-dpat significantly increased gr gene expression mainly in the ca1 region (31-44%). |
2000-12-28 |
2023-08-12 |
rat |