| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Yusim, O Ajilore, T Bliss, R Sapolsk. Glucocorticoids exacerbate insult-induced declines in metabolism in selectively vulnerable hippocampal cell fields. Brain research. vol 870. issue 1-2. 2000-08-21. PMID:10869507. |
when coupled with our prior report of cyanide disrupting metabolism only in ca1 explants, and the glutamatergic excitotoxin kainic acid disrupting metabolism only in ca3 explants, this demonstrates that microphysiometry can detect the selective regional vulnerability that characterizes the hippocampal response to these necrotic insults. |
2000-08-21 |
2023-08-12 |
rat |
| V Tancredi, M D'Antuono, C Cafè, S Giovedì, M C Buè, G D'Arcangelo, F Onofri, F Benfenat. The inhibitory effects of interleukin-6 on synaptic plasticity in the rat hippocampus are associated with an inhibition of mitogen-activated protein kinase ERK. Journal of neurochemistry. vol 75. issue 2. 2000-08-17. PMID:10899938. |
we have studied the effects of interleukin-6 (il-6) on the expression of paired pulse facilitation (ppf), posttetanic potentiation (ptp), and long-term potentiation (ltp) in the ca1 region of the hippocampus as well as on the activation of the signal transducer and activator of transcription-3 (stat3), the mitogen-activated protein kinase erk (mapk/erk), and the stress-activated protein kinase/c-jun nh(2)-terminal kinase (sapk/jnk). |
2000-08-17 |
2023-08-12 |
rat |
| M J West, C H Kawas, L J Martin, J C Troncos. The CA1 region of the human hippocampus is a hot spot in Alzheimer's disease. Annals of the New York Academy of Sciences. vol 908. 2000-08-17. PMID:10911964. |
the ca1 region of the human hippocampus is a hot spot in alzheimer's disease. |
2000-08-17 |
2023-08-12 |
human |
| M J West, C H Kawas, L J Martin, J C Troncos. The CA1 region of the human hippocampus is a hot spot in Alzheimer's disease. Annals of the New York Academy of Sciences. vol 908. 2000-08-17. PMID:10911964. |
data from an ongoing study of differences in the total number of neurons in the five major subdivisions of the hippocampal regions of the brains of patients with alzheimer's disease (ad) and normal age-matched controls confirm an earlier finding from our laboratories of a pronounced loss of ca1 neurons associated with ad. |
2000-08-17 |
2023-08-12 |
human |
| M Alkondon, M F Braga, E F Pereira, A Maelicke, E X Albuquerqu. alpha7 nicotinic acetylcholine receptors and modulation of gabaergic synaptic transmission in the hippocampus. European journal of pharmacology. vol 393. issue 1-3. 2000-08-11. PMID:10770998. |
the present report provides new findings regarding modulation of gamma-aminobutyric acid (gaba) transmission by alpha7 nicotinic receptor activity in ca1 interneurons of rat hippocampal slices. |
2000-08-11 |
2023-08-12 |
rat |
| A Kivi, T N Lehmann, R Kovács, A Eilers, R Jauch, H J Meencke, A von Deimling, U Heinemann, S Gabrie. Effects of barium on stimulus-induced rises of [K+]o in human epileptic non-sclerotic and sclerotic hippocampal area CA1. The European journal of neuroscience. vol 12. issue 6. 2000-08-11. PMID:10886343. |
in the hippocampus of patients with therapy-refractory temporal lobe epilepsy, glial cells of area ca1 might be less able to take up potassium ions via barium-sensitive inwardly rectifying and voltage-independent potassium channels. |
2000-08-11 |
2023-08-12 |
human |
| R Walz, G Lenz, R Roesler, M M Vianna, V Martins, R Brentani, R Rodnight, I Izquierd. Time-dependent enhancement of inhibitory avoidance retention and MAPK activation by post-training infusion of nerve growth factor into CA1 region of hippocampus of adult rats. The European journal of neuroscience. vol 12. issue 6. 2000-08-11. PMID:10886357. |
time-dependent enhancement of inhibitory avoidance retention and mapk activation by post-training infusion of nerve growth factor into ca1 region of hippocampus of adult rats. |
2000-08-11 |
2023-08-12 |
rat |
| R Walz, G Lenz, R Roesler, M M Vianna, V Martins, R Brentani, R Rodnight, I Izquierd. Time-dependent enhancement of inhibitory avoidance retention and MAPK activation by post-training infusion of nerve growth factor into CA1 region of hippocampus of adult rats. The European journal of neuroscience. vol 12. issue 6. 2000-08-11. PMID:10886357. |
here we investigate: (i) the effect of post-training infusion of ngf into the ca1 region of hippocampus on inhibitory avoidance (ia) retention in rats; (ii) the extension of the effect, in time and space, of ngf infusion into ca1 on the activity of mitogen-activated protein kinase (mapk, syn: erk1/2, p42/p44 mapk). |
2000-08-11 |
2023-08-12 |
rat |
| R Walz, G Lenz, R Roesler, M M Vianna, V Martins, R Brentani, R Rodnight, I Izquierd. Time-dependent enhancement of inhibitory avoidance retention and MAPK activation by post-training infusion of nerve growth factor into CA1 region of hippocampus of adult rats. The European journal of neuroscience. vol 12. issue 6. 2000-08-11. PMID:10886357. |
ngf was bilaterally injected into the ca1 regions of the dorsal hippocampus (0.05, 0.5 or 5.0 ng diluted in 0.5 microl of saline per side ) at 0, 120 or 360 min after ia training in rats. |
2000-08-11 |
2023-08-12 |
rat |
| L A Izquierdo, D M Barros, P G Ardenghi, P Pereira, C Rodrigues, H Choi, J H Medina, I Izquierd. Different hippocampal molecular requirements for short- and long-term retrieval of one-trial avoidance learning. Behavioural brain research. vol 111. issue 1-2. 2000-08-10. PMID:10840135. |
ten minutes prior to the retention test, through indwelling cannulae placed in the ca1 region of the dorsal hippocampus, they received 0.5 microl infusions of: saline, a vehicle (2% dimethylsulfoxide in saline), the glutamate nmda receptor blocker, aminophosphonopentanoic acid (ap5) (5.0 microg), the ampa/kainate receptor blocker, cyanonitroquinoxaline dione (cnqx) (0.25 or 1.25 microg), the metabotropic receptor antagonist, methylcarboxyphenylglycine (mcpg) (0.5 or 2.5 microg), the inhibitor of calcium/calmodulin-dependent protein kinase ii (kn62) (3.5 microg), the inhibitor of camp-dependent protein kinase (pka), rp-camps (0.1 or 0.5 microg), the stimulant of the same enzyme, sp-camps (0.1 or 0.5 microg), or the inhibitor of the mitogen-activated protein kinase (mapk) kinase, pd098059 (10 or 50 microm). |
2000-08-10 |
2023-08-12 |
rat |
| J A White, M I Banks, R A Pearce, N J Kopel. Networks of interneurons with fast and slow gamma-aminobutyric acid type A (GABAA) kinetics provide substrate for mixed gamma-theta rhythm. Proceedings of the National Academy of Sciences of the United States of America. vol 97. issue 14. 2000-08-10. PMID:10869419. |
for example, region ca1 of the hippocampus contains a slower class of gaba(a) (gaba(a,slow)) synapses, believed to be generated by a distinct group of interneurons. |
2000-08-10 |
2023-08-12 |
Not clear |
| A Takeuchi, M C Irizarry, K Duff, T C Saido, K Hsiao Ashe, M Hasegawa, D M Mann, B T Hyman, T Iwatsub. Age-related amyloid beta deposition in transgenic mice overexpressing both Alzheimer mutant presenilin 1 and amyloid beta precursor protein Swedish mutant is not associated with global neuronal loss. The American journal of pathology. vol 157. issue 1. 2000-08-08. PMID:10880403. |
to analyze the relationship between the deposition of amyloid beta peptides (abeta) and neuronal loss in transgenic models of alzheimer's disease (ad), we examined the frontal neocortex (fc) and ca1 portion of hippocampus (ca1) in psapp mice doubly expressing ad-associated mutant presenilin 1 (ps1) and swedish-type mutant beta amyloid precursor protein (appsw) by morphometry of abeta burden and neuronal counts. |
2000-08-08 |
2023-08-12 |
mouse |
| J A Gray, G Grigoryan, D Virley, S Patel, J D Sinden, H Hodge. Conditionally immortalized, multipotential and multifunctional neural stem cell lines as an approach to clinical transplantation. Cell transplantation. vol 9. issue 2. 2000-08-07. PMID:10811390. |
experiments are described using rats with two kinds of brain damage and consequent cognitive deficit (in the morris water maze, three-door runway, and radial maze): 1) ischemic damage to the ca1 hippocampal cell field after four-vessel occlusion (4vo), and 2) damage to the forebrain cholinergic projection system by local injection of excitotoxins to the nuclei of origin or prolonged ethanol administration. |
2000-08-07 |
2023-08-12 |
rat |
| J A Gray, G Grigoryan, D Virley, S Patel, J D Sinden, H Hodge. Conditionally immortalized, multipotential and multifunctional neural stem cell lines as an approach to clinical transplantation. Cell transplantation. vol 9. issue 2. 2000-08-07. PMID:10811390. |
cell suspension grafts derived from primary fetal brain tissue display a stringent requirement for homotypical cell replacement in the 4vo model: cells from the embryonic day (e)18-19 ca1 hippocampal subfield, but not from ca3 or dentate gyrus or from e16 basal forebrain (cholinergic rich) led to recovery of cognitive function. |
2000-08-07 |
2023-08-12 |
rat |
| I Bayazitov, A Kleschevniko. Afferent high strength tetanizations favour potentiation of the NMDA vs. AMPA receptor-mediated component of field EPSP in CA1 hippocampal slices of rats. Brain research. vol 866. issue 1-2. 2000-08-07. PMID:10825494. |
afferent high strength tetanizations favour potentiation of the nmda vs. ampa receptor-mediated component of field epsp in ca1 hippocampal slices of rats. |
2000-08-07 |
2023-08-12 |
rat |
| X D Fan, X M Li, A V Juori. Substantia nigra pars reticulata lesion induces preconvulsive behavior and changes in glutamate receptor gene expression in the rat brain. Brain research. vol 867. issue 1-2. 2000-08-04. PMID:10837796. |
unilateral injection of exogenous da into the anterior region of the snpr induced rapid and short lasting preconvulsive behavior up to wet dog shakes stage and a significant reduction of gene expression for glur1, glur2 and nmdar1 subunits in rat hippocampal subfields including ca1 through ca4 and dentate gyrus (dg) at 1 day after nigral da injection. |
2000-08-04 |
2023-08-12 |
rat |
| J R Moyer, J M Power, L T Thompson, J F Disterhof. Increased excitability of aged rabbit CA1 neurons after trace eyeblink conditioning. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 14. 2000-08-03. PMID:10884331. |
cellular properties of ca1 neurons were studied in hippocampal slices 24 hr after acquisition of trace eyeblink conditioning in young adult and aging rabbits. |
2000-08-03 |
2023-08-12 |
rabbit |
| F Wei, Z C Xu, Z Qu, J Milbrandt, M Zhu. Role of EGR1 in hippocampal synaptic enhancement induced by tetanic stimulation and amputation. The Journal of cell biology. vol 149. issue 7. 2000-08-01. PMID:10871275. |
here we present evidence that excitatory glutamatergic synapses within the ca1 region of the hippocampus may play a role in storing pain-related information. |
2000-08-01 |
2023-08-12 |
mouse |
| D Y Ruan, K F Yan, S Y Ge, Y Z Xu, J T Chen, M Wan. Effects of chronic lead exposure on short-term and long-term depression in area CA1 of the rat hippocampus in vivo. Chemosphere. vol 41. issue 1-2. 2000-07-27. PMID:10819196. |
effects of chronic lead exposure on short-term and long-term depression in area ca1 of the rat hippocampus in vivo. |
2000-07-27 |
2023-08-12 |
rat |
| D Y Ruan, K F Yan, S Y Ge, Y Z Xu, J T Chen, M Wan. Effects of chronic lead exposure on short-term and long-term depression in area CA1 of the rat hippocampus in vivo. Chemosphere. vol 41. issue 1-2. 2000-07-27. PMID:10819196. |
chronic developmental lead (pb) exposure to the rat has been reported to impair the long-term potentiation (ltp) in area ca1 and dg of the hippocampus. |
2000-07-27 |
2023-08-12 |
rat |