| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ali Dehghani, Gholam Hossein Meftahi, Hedayat Sahrae. The administration of a phentolamine infusion into the basolateral amygdala enhances long-term memory and diminishes anxiety-like behavior in stressed rats. Behavioural pharmacology. 2024-10-22. PMID:39436284. |
the objective of this study was to explore whether inhibition of α-adrenergic receptors (by phentolamine, an α-adrenergic receptor antagonist) in the bla can reduce foot-shock stress-induced anxiety-like behavior, memory deficits, and long-term potentiation (ltp) deficits within the ca1 region of the rat hippocampus. |
2024-10-22 |
2024-10-24 |
rat |
| Aliza A Le, Julie C Lauterborn, Yousheng Jia, Conor D Cox, Gary Lynch, Christine M Gal. Metabotropic NMDAR Signaling Contributes to Sex Differences in Synaptic Plasticity and Episodic Memory. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024-10-18. PMID:39424366. |
blocking nmdar channels with mk-801 eliminated ltp expression in hippocampal field ca1 of both sexes but left intact theta burst stimulation (tbs)-induced actin polymerization within dendritic spines. |
2024-10-18 |
2024-10-21 |
Not clear |
| Daniel S Scott, Muthumeenakshi Subramanian, Jun Yamamoto, Carol A Tamming. Schizophrenia pathology reverse-translated into mouse shows hippocampal hyperactivity, psychosis behaviors and hyper-synchronous events. Molecular psychiatry. 2024-10-15. PMID:39407000. |
post-mortem analyses of brain tissue from human schizophrenia brain show decreased expression of the nmdar subunit glun1 confined to the dentate gyrus with evidence of downstream hippocampal hyperactivity in ca3 and ca1. |
2024-10-15 |
2024-10-18 |
mouse |
| Daniel S Scott, Muthumeenakshi Subramanian, Jun Yamamoto, Carol A Tamming. Schizophrenia pathology reverse-translated into mouse shows hippocampal hyperactivity, psychosis behaviors and hyper-synchronous events. Molecular psychiatry. 2024-10-15. PMID:39407000. |
dg inhibition during adolescence generates an increase in hippocampal activity in ca3 and ca1, impairs social cognition and spatial working memory, as well as shows evidence of increased activity in local field potentials as spontaneous synchronous bursts of activity, which we term hyper-synchronous events (hses) in hippocampus. |
2024-10-15 |
2024-10-18 |
mouse |
| Sanggeon Park, Mijeong Park, Eun Joo Kim, Jeansok J Kim, Yeowool Huh, Jeiwon Ch. Distinct Disruptions in CA1 and CA3 Place Cell Function in Alzheimer's Disease Mice. bioRxiv : the preprint server for biology. 2024-10-10. PMID:39386433. |
our results suggest that distinct alteration in the physiological properties of ca1 and ca3 place cells, coupled with disrupted hippocampal theta rhythm in ca1, may collectively contribute to impaired hippocampal-dependent spatial learning and memory in ad. |
2024-10-10 |
2024-10-12 |
mouse |
| Honglin Jia, Xu Chen, Zhengting Liang, Ruining Liang, Jinhong Wu, Yanling Hu, Wenjun Cui, Xingping Zhan. Senegenin regulates the mechanism of insomnia through the Keap1/Nrf2/PINK1/Parkin pathway mediated by GAD67. Journal of sleep research. 2024-10-09. PMID:39380353. |
insomnia rats exhibited changes in sleep rhythm, learning, and exploration dysfunction, pathological changes in the ca1 region of the hippocampus, and differential expression of gad67 and sleep-related factors. |
2024-10-09 |
2024-10-11 |
rat |
| Sampath K T Kapanaiah, Christina Grimm, Dennis Kätze. Acute optogenetic induction of the prodromal endophenotype of CA1 hyperactivity causes schizophrenia-related deficits in cognition and salience attribution. Schizophrenia (Heidelberg, Germany). vol 10. issue 1. 2024-10-08. PMID:39379378. |
hyperactivity of the human anterior hippocampus has been reported to spread from its ca1 subfield to the subiculum around the onset of first-episode psychosis and could be a cellular target for early therapeutic intervention in the schizophrenia prodrome. |
2024-10-08 |
2024-10-11 |
mouse |
| Aditi Bishnoi, Sachin S Deshmuk. Comparable Theta Phase Coding Dynamics Along the Transverse Axis of CA1. Hippocampus. 2024-10-05. PMID:39368076. |
topographical projection patterns from the entorhinal cortex to area ca1 of the hippocampus have led to a hypothesis that proximal ca1 (pca1, closer to ca2) is spatially more selective than distal ca1 (dca1, closer to the subiculum). |
2024-10-05 |
2024-10-08 |
Not clear |
| Zhipeng Li, Jing Wang, Chongyang Tang, Peng Wang, Peng Ren, Siyang Li, Liye Yi, Qiuyi Liu, Lili Sun, Kaizhou Li, Wencai Ding, Hongbo Bao, Lifen Yao, Meng Na, Guoming Luan, Xia Lian. Coordinated NREM sleep oscillations among hippocampal subfields modulate synaptic plasticity in humans. Communications biology. vol 7. issue 1. 2024-10-01. PMID:39354050. |
using human intracranial recordings from 25 epilepsy patients, we find that hippocampal subfields, including dg/ca3, ca1, and sub, all exhibit significant delta and spindle power during nrem sleep. |
2024-10-01 |
2024-10-04 |
human |
| Mingxin Ding, Porter L Tomsick, Ryan A Young, Shantanu P Jadha. Ventral tegmental area dopamine neural activity switches simultaneously with rule representations in the prefrontal cortex and hippocampus. bioRxiv : the preprint server for biology. 2024-09-24. PMID:39314328. |
we addressed these questions using simultaneous recording of neuronal population activity from the hippocampal area ca1, pfc and ventral tegmental area (vta) in male th-cre rats performing two spatial working memory tasks with frequent rule switches in blocks of trials. |
2024-09-24 |
2024-09-26 |
rat |
| Jingjing Ji, Yirong Xu, Yanni Wang, Guangheng Zhang, Xiaoai Tian, Yeping Zhang, Jiaxuan Re. miR-351-5p regulation of CPEB3 affecting aluminium-induced learning and memory impairment in SD rats. Environmental pollution (Barking, Essex : 1987). 2024-09-22. PMID:39307336. |
double luciferase reporter assay results showed that cpeb3 was a direct target of mir-351-5p, while electron microscopy suggested that aluminium could damage mitochondria and synapses in the ca1 of the hippocampus. |
2024-09-22 |
2024-09-26 |
rat |
| Juraj Bevandić, Federico Stella, H Freyja Ólafsdótti. Parallel maturation of rodent hippocampal memory and CA1 task representations. Current biology : CB. 2024-09-21. PMID:39305898. |
parallel maturation of rodent hippocampal memory and ca1 task representations. |
2024-09-21 |
2024-09-24 |
rat |
| Juraj Bevandić, Federico Stella, H Freyja Ólafsdótti. Parallel maturation of rodent hippocampal memory and CA1 task representations. Current biology : CB. 2024-09-21. PMID:39305898. |
together, these results suggest that a hallmark of hippocampal memory development may be the emergence of contextually specific ca1 representations driven by the maturation of ca1 micro-circuits. |
2024-09-21 |
2024-09-24 |
rat |
| Aaron Lam, Angela L D'Rozario, Jake R Palmer, Andrew McKinnon, Marshall R Dalton, Nicole Espinosa, Loren Mowszowski, Craig L Phillips, Ronald R Grunstein, Sharon L Naismit. Hypoxemia during rapid eye movement sleep mediates memory impairment in older adults at risk for dementia via CA1 hippocampal volume loss. European journal of neurology. 2024-09-20. PMID:39302096. |
hypoxemia during rapid eye movement sleep mediates memory impairment in older adults at risk for dementia via ca1 hippocampal volume loss. |
2024-09-20 |
2024-09-22 |
Not clear |
| Anoop Manakkadan, Dolly Krishnan, Sheila Rui Xia Ang, Sreedharan Sajikuma. Slow Release of Hydrogen Sulfide in CA1 Hippocampal Neurons Rescues Long-Term Synaptic Plasticity and Associativity in an Amyloid-β Induced Model of Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2024-09-20. PMID:39302367. |
slow release of hydrogen sulfide in ca1 hippocampal neurons rescues long-term synaptic plasticity and associativity in an amyloid-β induced model of alzheimer's disease. |
2024-09-20 |
2024-09-22 |
mouse |
| Felix Michaud, Ruggiero Francavilla, Dimitry Topolnik, Parisa Iloun, Suhel Tamboli, Frederic Calon, Lisa Topolni. Altered firing output of VIP interneurons and early dysfunctions in CA1 hippocampal circuits in the 3xTg mouse model of Alzheimer's disease. eLife. vol 13. 2024-09-12. PMID:39264364. |
altered firing output of vip interneurons and early dysfunctions in ca1 hippocampal circuits in the 3xtg mouse model of alzheimer's disease. |
2024-09-12 |
2024-09-14 |
mouse |
| Conor C Dorian, Jiannis Taxidis, Peyman Golshan. Non-spatial hippocampal behavioral timescale synaptic plasticity during working memory is gated by entorhinal inputs. bioRxiv : the preprint server for biology. 2024-09-10. PMID:39253411. |
behavioral timescale synaptic plasticity (btsp) is a form of synaptic potentiation where the occurrence of a single large plateau potential in ca1 hippocampal neurons leads to the formation of reliable place fields during spatial learning tasks. |
2024-09-10 |
2024-09-13 |
mouse |
| Conor C Dorian, Jiannis Taxidis, Peyman Golshan. Non-spatial hippocampal behavioral timescale synaptic plasticity during working memory is gated by entorhinal inputs. bioRxiv : the preprint server for biology. 2024-09-10. PMID:39253411. |
altogether, odor-specific information from lec and strong odor-timed activity from mec are crucial for driving btsp in ca1, which is a synaptic plasticity mechanism for generation of both spatial and non-spatial responses in the hippocampus that may play a role in explaining representational drift and one-shot learning of non-spatial information. |
2024-09-10 |
2024-09-13 |
mouse |
| Pingping Zhao, Changliang Guo, Mian Xie, Liangyi Chen, Peyman Golshani, Daniel Aharon. MiniXL: An open-source, large field-of-view epifluorescence miniature microscope for mice capable of single-cell resolution and multi-brain region imaging. bioRxiv : the preprint server for biology. 2024-09-04. PMID:39229051. |
we demonstrated the capability of minixl recording the activity of large neuronal population in both subcortical area (hippocampal dorsal ca1) and deep brain regions (medial prefrontal cortex, mpfc and nucleus accumbens, nac). |
2024-09-04 |
2024-09-06 |
mouse |
| Bradley G Karat, Sila Genc, Erika P Raven, Marco Palombo, Ali R Khan, Derek K Jone. The developing hippocampus: Microstructural evolution through childhood and adolescence. bioRxiv : the preprint server for biology. 2024-09-04. PMID:39229062. |
a significant negative correlation between age and mr apparent soma radius was found in the subiculum and ca1 throughout the anterior and body of the hippocampus. |
2024-09-04 |
2024-09-06 |
human |