| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Miriam Renz, Pascal Siegert, Katja Mohnke, Robert Ruemmler, Katrin Frauenknecht, Clemens Sommer, Anja Harde. Precise Definition of Porcine Hippocampal Cornu Ammonis 2: High Histoarchitectural Similarity to Humans but Unequal Sensitivity to Hypoxia. Biomedicines. vol 12. issue 8. 2024-08-29. PMID:39200360. |
experimental animal studies of hypoxic-ischemic injury of the hippocampus of pigs are limited due to the unprecise definition of hippocampal subfields, cornu ammonis 1 to 4, compared to humans. |
2024-08-29 |
2024-09-01 |
human |
| S Li, J Wang, J V Andersen, B I Aldana, B Zhang, E V Prochownik, P A Rosenber. Misprogramming of glucose metabolism impairs recovery of hippocampal slices from neuronal GLT-1 knockout mice and contributes to excitotoxic injury through mitochondrial superoxide production. Journal of neurochemistry. 2024-08-28. PMID:39193789. |
we have previously reported a failure of recovery of synaptic function in the ca1 region of acute hippocampal slices from mice with a conditional neuronal knockout (ko) of glt-1 (eaat2, slc1a2) driven by synapsin-cre (synglt-1 ko). |
2024-08-28 |
2024-08-30 |
mouse |
| Ruth A Singer, Veronika Rajchin, Kwanghoon Park, Nathaniel Heintz, Robert B Darnel. Opto-CLIP reveals dynamic FMRP regulation of mRNAs upon CA1 neuronal activation. bioRxiv : the preprint server for biology. 2024-08-26. PMID:39185177. |
since molecular studies have demonstrated that synaptic plasticity in ca1 excitatory hippocampal neurons is protein-synthesis dependent, together these observations have suggested a potential role for fmrp in synaptic plasticity in fxs. |
2024-08-26 |
2024-08-28 |
Not clear |
| Zhengshan Liu, Yu H Sun, Yue Ren, Jessica Marie Perez, Daniel Scott, Carol Tamming. Upregulated solute-carrier family genes in the hippocampus of schizophrenia can be rescued by antipsychotic medications. Schizophrenia research. vol 272. 2024-08-25. PMID:39182310. |
our previous studies have found that functional changes in the hippocampal circuit from dentate gyrus (dg) to cornu ammonis 3 and 1 (ca3, ca1) are highly associated with schizophrenia (sz). |
2024-08-25 |
2024-08-28 |
human |
| Rocio Alfaro-Ruiz, Alejandro Martín-Belmonte, Carolina Aguado, Ana Esther Moreno-Martínez, Yugo Fukazawa, Rafael Lujá. Selective disruption of synaptic NMDA receptors of the hippocampal trisynaptic circuit in Aβ pathology. Biological research. vol 57. issue 1. 2024-08-23. PMID:39175009. |
using quantitative sds-frl, we unravelled the molecular organisation of glun1 in seven excitatory synapse populations at a high spatial resolution in the ca1 and ca3 fields and the dg of the hippocampus in 12-month-old app/ps1 mice. |
2024-08-23 |
2024-08-25 |
mouse |
| Paige L Graney, Evelyn L Sarno, Jessie E Miller, Christine K Wagne. Implications of Developmental 17-OHPC Exposure on the Mesocorticolimbic Serotonergic and Dopaminergic Pathways and Adolescent Mood-Related Behavior in Rats. Developmental psychobiology. vol 66. issue 6. 2024-08-21. PMID:39164823. |
developmental 17-ohpc exposure significantly increased the density of serotonin transporter-ir fibers in ca1, ca2/3, and the suprapyramidal blade of dentate gyrus in hippocampus and significantly reduced the density of th-ir fibers within the nucleus accumbens shell in males but had no effect in females during adolescence. |
2024-08-21 |
2024-08-23 |
rat |
| Kyu Ri Hahn, Hyun Jung Kwon, Dae Won Kim, In Koo Hwang, Yeo Sung Yoo. Therapeutic Options of Crystallin Mu and Protein Disulfide Isomerase A3 for Cuprizone-Induced Demyelination in Mouse Hippocampus. Neurochemical research. 2024-08-20. PMID:39164609. |
immunohistochemical staining validated these protein expression patterns in the hippocampus, revealing that both pdia3 and crym were downregulated in the hippocampal ca1 region during demyelination and upregulated during remyelination. |
2024-08-20 |
2024-08-23 |
mouse |
| Rui Wang, Linzhong Zhang, Xia Wang, Wen Li, Tingliang Jian, Pengcheng Yin, Xinzhi Wang, Qianwei Chen, Xiaowei Chen, Han Qi. Electrophysiological activity pattern of mouse hippocampal CA1 and dentate gyrus under isoflurane anesthesia. Frontiers in cellular neuroscience. vol 18. 2024-08-06. PMID:39104439. |
the ca1 and dentate gyrus (dg), serving as the primary efferent and gateway of the hippocampal trisynaptic circuit facilitating cognitive learning and memory functions, exhibit significant differences in cellular composition, molecular makeup, and responses to various stimuli. |
2024-08-06 |
2024-08-08 |
mouse |
| Chen Yan, Valentina Mercaldo, Alexander D Jacob, Emily Kramer, Andrew Mocle, Adam I Ramsaran, Lina Tran, Asim J Rashid, Sungmo Park, Nathan Insel, A David Redish, Paul W Frankland, Sheena A Jossely. Higher-order interactions between hippocampal CA1 neurons are disrupted in amnestic mice. Nature neuroscience. 2024-07-19. PMID:39030342. |
here we tested whether contextual threat memory retrieval in mice relies on higher-order interactions between dorsal ca1 hippocampal neurons requiring learning-induced dendritic spine plasticity. |
2024-07-19 |
2024-07-22 |
mouse |
| Li Wei, Xiaopeng Yu, Hui Chen, Yupeng D. The role of P2X4R in regulating CA1 hippocampal synaptic impairment in LPS-induced depression. Journal of affective disorders. 2024-07-17. PMID:39019229. |
the role of p2x4r in regulating ca1 hippocampal synaptic impairment in lps-induced depression. |
2024-07-17 |
2024-07-20 |
Not clear |
| Rabia Anjum, Vernon R J Clarke, Yutaro Nagasawa, Hideji Murakoshi, Suzanne Paradi. Rem2 interacts with CaMKII at synapses and restricts long-term potentiation in hippocampus. PloS one. vol 19. issue 7. 2024-07-12. PMID:38995900. |
here, we report that knock out of rem2 enhances ltp at the schaffer collateral to ca1 synapse in hippocampus, consistent with an inhibitory action of rem2 on camkii in vivo. |
2024-07-12 |
2024-07-15 |
mouse |
| Sara N Bramlett, Shana M Fitzmaurice, Nicholas H Harbin, Wuji Yan, Charan Bandlamudi, G Emme Van Doorn, Yoland Smith, John R Heple. Regulator of G Protein Signaling 14 protein expression profile in the adult mouse brain. bioRxiv : the preprint server for biology. 2024-07-09. PMID:38979272. |
however, our more recent work with adult rhesus macaque brain shows that rgs14 is found in multiple neuron populations throughout hippocampal area ca1 and ca2, caudate nucleus, putamen, globus pallidus, substantia nigra, and amygdala in the adult rhesus monkey brain. |
2024-07-09 |
2024-07-12 |
mouse |
| Wenyan Zhao, Wei Zhang, Yingying Hu, Yuliang Zhou, Jinying Zhao, Yahong Li, Zhipeng X. AdipoRon Ameliorates Synaptic Dysfunction and Inhibits tau Hyperphosphorylation through the AdipoR/AMPK/mTOR Pathway in T2DM Mice. Neurochemical research. vol 49. issue 8. 2024-07-09. PMID:38819697. |
in addition, adiporon treatment up-regulated synaptic proteins (psd95, syn, gap43, and syp), increased the number of hippocampal synapses and attenuated synaptic damage, including the length, the number and the density of dendritic spines in ca1 and dg regions. |
2024-07-09 |
2024-07-12 |
mouse |
| M Angeles Luque, Sara Morcuende, Blas Torres, Luis Herrer. Kv7/M channel dysfunction produces hyperexcitability in hippocampal CA1 pyramidal cells of Fmr1 knockout mice. The Journal of physiology. 2024-07-08. PMID:38976504. |
here we show that pyramidal cells (pcs) in the dorsal ca1 region of the hippocampus elicited a larger action potential (ap) number in response to suprathreshold stimulation in juvenile fmr1 knockout (ko) than wild-type (wt) mice. |
2024-07-08 |
2024-07-12 |
mouse |
| Mona Rahdar, Shima Davoudi, Samaneh Dehghan, Mohammad Javan, Narges Hosseinmardi, Gila Behzadi, Mahyar Janahmad. Reversal of electrophysiological and behavioral deficits mediated by 5-HT7 receptor upregulation following LP-211 treatment in an autistic-like rat model induced by prenatal valproic acid exposure. Neuropharmacology. vol 257. 2024-07-05. PMID:38964596. |
recently, we have reported research has shown a significant decrease in serotonergic neurons originating from the raphe nuclei and projecting to the ca1 region of the dorsal hippocampus in autistic-like rats. |
2024-07-05 |
2024-07-08 |
rat |
| Mona Rahdar, Shima Davoudi, Samaneh Dehghan, Mohammad Javan, Narges Hosseinmardi, Gila Behzadi, Mahyar Janahmad. Reversal of electrophysiological and behavioral deficits mediated by 5-HT7 receptor upregulation following LP-211 treatment in an autistic-like rat model induced by prenatal valproic acid exposure. Neuropharmacology. vol 257. 2024-07-05. PMID:38964596. |
this study presents new evidence indicating an upregulation of 5-ht7r in the ca1 subregion of the hippocampus following the induction of autism. |
2024-07-05 |
2024-07-08 |
rat |
| Qinghe Li, Zhicui Ouyang, Yunqiao Zhang, Zhen Li, Xing Zhu, Zhen Tan. Effect of Early Inhibition of Toll-Like Receptor 4 on Hippocampal Plasticity in a Neonatal Rat Model of Hypoxic-Ischemic Brain Damage. Molecular neurobiology. 2024-07-02. PMID:38954251. |
finally,tak-242 increased the percentage of third-grade dendritic mushroom spines processes in the basal and apical segments of neurons in the hippocampal ca1 region at 21 days after hibd.therefore, we conclude that preinhibition of tlr4 prior to neonatal hibd improved the plasticity of the hippocampus. |
2024-07-02 |
2024-07-06 |
rat |
| Ana Paula Rodrigues Martini, Livia Machado Schlemmer, Joelma Alves Lucio Padilha, Rafael Bandeira Fabres, Natividade de Sá Couto Pereira, Lenir Orlandi Pereira, Carla Dalmaz, Carlos Alexandre Nett. Acrobatic training prevents learning impairments and astrocyte remodeling in the hippocampus of rats undergoing chronic cerebral hypoperfusion: sex-specific benefits. Frontiers in rehabilitation sciences. vol 5. 2024-06-28. PMID:38939055. |
we investigated the effects of acrobatic training on astrocyte remodeling in the ca1 and ca3 subfields of the hippocampus and spatial memory impairment in male and female rats at different stages of the two-vessel occlusion (2vo) model. |
2024-06-28 |
2024-06-30 |
rat |
| D K Avrova, L V Bayunova, N F Avrova, I O Zakharov. The Effect of Intranasal Administration of Gangliosides on the Viability of CA1 Hippocampal Neurons in Rat Two-Vessel Occlusion Model of Forebrain Ischemia/Reperfusion Injury. Bulletin of experimental biology and medicine. 2024-06-21. PMID:38907060. |
the expression of neurotrophic factor bdnf in the ca1 region of hippocampus did not differ in sham-operated rats and animals exposed to ischemia/reperfusion. |
2024-06-21 |
2024-06-24 |
rat |
| Ivette Espinoza, Francisco Cabrera, Julio César Morales-Medina, Ma de Jesús Gómez-Villalobos, Gonzalo Flore. The administration of Cerebrolysin elicits neuroprotective and neurorepair effects in an animal model of type 1 diabetes mellitus. Behavioural brain research. 2024-06-19. PMID:38897418. |
this research aims to investigate the neuroprotective and neurorepair effect of cbl on the cytoarchitecture of neurons and spine density in pyramidal neurons of the prefrontal (pfc) and the ca1 region of the dorsal hippocampus, as well as spheroidal neurons of the dentate gyrus (dg), in stz-induced dm. |
2024-06-19 |
2024-06-22 |
rat |