Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Xun Wang, Bing Wang, Jianping Zhao, Caixing Liu, Xianpeng Qu, Yuhuan L. MiR-155 is involved in major depression disorder and antidepressant treatment via targeting SIRT1. Bioscience reports. vol 38. issue 6. 2019-07-22. PMID:30482883. |
mir-155 is involved in major depression disorder and antidepressant treatment via targeting sirt1. |
2019-07-22 |
2023-08-13 |
human |
Claire L McGrory, Karen M Ryan, Erik Kolshus, Martha Finnegan, Declan M McLoughli. Peripheral blood SIRT1 mRNA levels in depression and treatment with electroconvulsive therapy. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 28. issue 9. 2019-05-03. PMID:30017261. |
peripheral blood sirt1 mrna levels in depression and treatment with electroconvulsive therapy. |
2019-05-03 |
2023-08-13 |
Not clear |
Claire L McGrory, Karen M Ryan, Erik Kolshus, Martha Finnegan, Declan M McLoughli. Peripheral blood SIRT1 mRNA levels in depression and treatment with electroconvulsive therapy. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 28. issue 9. 2019-05-03. PMID:30017261. |
a recent genome-wide association study has identified a locus for major depression in the sirtuin1 gene (sirt1) and lower blood levels of sirt1 mrna in patients with depression have also been observed in two studies. |
2019-05-03 |
2023-08-13 |
Not clear |
Claire L McGrory, Karen M Ryan, Erik Kolshus, Martha Finnegan, Declan M McLoughli. Peripheral blood SIRT1 mRNA levels in depression and treatment with electroconvulsive therapy. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 28. issue 9. 2019-05-03. PMID:30017261. |
to our knowledge, no studies have examined the effect of treatment on sirt1 levels in patients with depression. |
2019-05-03 |
2023-08-13 |
Not clear |
Claire L McGrory, Karen M Ryan, Erik Kolshus, Martha Finnegan, Declan M McLoughli. Peripheral blood SIRT1 mRNA levels in depression and treatment with electroconvulsive therapy. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 28. issue 9. 2019-05-03. PMID:30017261. |
there was no relationship between baseline pre-ect sirt1 levels and depression severity, change in mood scores, suicidality, depression polarity, presence of psychosis, or response to treatment. |
2019-05-03 |
2023-08-13 |
Not clear |
Claire L McGrory, Karen M Ryan, Erik Kolshus, Martha Finnegan, Declan M McLoughli. Peripheral blood SIRT1 mRNA levels in depression and treatment with electroconvulsive therapy. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 28. issue 9. 2019-05-03. PMID:30017261. |
these results indicate that reduced peripheral blood sirt1 mrna could be a trait feature of depression. |
2019-05-03 |
2023-08-13 |
Not clear |
Sokrates Stein, Stephan Winnik, Christian M Matte. Brain-derived neurotrophic factor Val66Met polymorphism in depression and thrombosis: SIRT1 as a possible mediator. European heart journal. vol 38. issue 18. 2019-04-12. PMID:26715164. |
brain-derived neurotrophic factor val66met polymorphism in depression and thrombosis: sirt1 as a possible mediator. |
2019-04-12 |
2023-08-13 |
Not clear |
Xue Liang, Yang Liu, Shiyu Jia, Xiaomin Xu, Meixue Dong, Youdong We. SIRT1: The Value of Functional Outcome, Stroke-Related Dementia, Anxiety, and Depression in Patients with Acute Ischemic Stroke. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. vol 28. issue 1. 2019-02-04. PMID:30361109. |
sirt1: the value of functional outcome, stroke-related dementia, anxiety, and depression in patients with acute ischemic stroke. |
2019-02-04 |
2023-08-13 |
Not clear |
Guofang Lu, Jianguo Li, Hongmei Zhang, Xin Zhao, Liang-Jun Yan, Xiaorong Yan. Role and Possible Mechanisms of Sirt1 in Depression. Oxidative medicine and cellular longevity. vol 2018. 2018-09-05. PMID:29643977. |
role and possible mechanisms of sirt1 in depression. |
2018-09-05 |
2023-08-13 |
Not clear |
Hee-Dae Kim, Jennifer Hesterman, Tanessa Call, Samantha Magazu, Elizabeth Keeley, Kristyna Armenta, Hope Kronman, Rachael L Neve, Eric J Nestler, Deveroux Ferguso. SIRT1 Mediates Depression-Like Behaviors in the Nucleus Accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 32. 2017-07-14. PMID:27511015. |
in the present study, we show that chronic social defeat stress, an ethologically validated model of depression in mice, increases sirt1 levels in the nucleus accumbens (nac), a key brain reward region. |
2017-07-14 |
2023-08-13 |
mouse |
L Lo Iacono, F Visco-Comandini, A Valzania, M T Viscomi, M Coviello, A Giampà, L Roscini, E Bisicchia, A Siracusano, A Troisi, S Puglisi-Allegra, V Carol. Adversity in childhood and depression: linked through SIRT1. Translational psychiatry. vol 5. 2016-05-11. PMID:26327687. |
adversity in childhood and depression: linked through sirt1. |
2016-05-11 |
2023-08-13 |
mouse |
L Lo Iacono, F Visco-Comandini, A Valzania, M T Viscomi, M Coviello, A Giampà, L Roscini, E Bisicchia, A Siracusano, A Troisi, S Puglisi-Allegra, V Carol. Adversity in childhood and depression: linked through SIRT1. Translational psychiatry. vol 5. 2016-05-11. PMID:26327687. |
we also performed a pilot study in humans, in which the blood levels of sirt1 correlated significantly with the severity of symptoms in major depression patients, especially in those who received less parental care during childhood. |
2016-05-11 |
2023-08-13 |
mouse |
Sung Chung, Hee Jeong Kim, In Seon Yoon, Hyun Ju Kim, Sun Hye Choi, Yong Sik Kim, Kyung Ho Shi. Electroconvulsive shock increases SIRT1 immunoreactivity in the mouse hippocampus and hypothalamus. The journal of ECT. vol 29. issue 2. 2014-01-08. PMID:23519217. |
recent study shows that silent mating-type information regulation 2 homolog 1 (sirt1) regulation may be involved with depression. |
2014-01-08 |
2023-08-12 |
mouse |
Sung Chung, Hee Jeong Kim, In Seon Yoon, Hyun Ju Kim, Sun Hye Choi, Yong Sik Kim, Kyung Ho Shi. Electroconvulsive shock increases SIRT1 immunoreactivity in the mouse hippocampus and hypothalamus. The journal of ECT. vol 29. issue 2. 2014-01-08. PMID:23519217. |
the present study was designed to observe whether ecs dynamically regulates sirt1 levels in the hippocampus and hypothalamus; both of these regions have been implicated in the pathophysiology of depression. |
2014-01-08 |
2023-08-12 |
mouse |