| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B Waldrop, T A Christensen, J G Hildebran. GABA-mediated synaptic inhibition of projection neurons in the antennal lobes of the sphinx moth, Manduca sexta. Journal of comparative physiology. A, Sensory, neural, and behavioral physiology. vol 161. issue 1. 1987-09-24. PMID:3039128. |
epsps can be protected from depression by application of gaba. |
1987-09-24 |
2023-08-11 |
Not clear |
| H R Olpe, J Heid, H Bittiger, M W Steinman. Substance P depresses neuronal activity in the rat olfactory bulb in vitro and in vivo: possible mediation via gamma-aminobutyric acid release. Brain research. vol 412. issue 2. 1987-08-28. PMID:2440522. |
it appears that substance p acts by means of releasing gaba which in turn evokes the observed cell depression because the depressant effects were completely abolished by bath-applied bicuculline (10 microm) and picrotoxin (100 microm). |
1987-08-28 |
2023-08-11 |
rat |
| A M Taveira da Silva, B Hartley, P Hamosh, J A Quest, R A Gilli. Respiratory depressant effects of GABA alpha- and beta-receptor agonists in the cat. Journal of applied physiology (Bethesda, Md. : 1985). vol 62. issue 6. 1987-08-28. PMID:3038827. |
we conclude that activation of gaba alpha- and beta-receptors produces cardiorespiratory depression. |
1987-08-28 |
2023-08-11 |
cat |
| J Ong, D I Kerr, A R Johnsto. Differing actions of beta-phenyl-GABA and baclofen in the guinea pig isolated ileum. Neuroscience letters. vol 77. issue 1. 1987-08-10. PMID:3601209. |
in the guinea-pig isolated ileum, both gamma-aminobutyric acid (gaba) and baclofen induced a dose-dependent depression of cholinergic twitch contractions to transmural stimulation, sensitive to delta-aminovaleric acid (dava) and phosphonobaclofen (phaclofen). |
1987-08-10 |
2023-08-11 |
Not clear |
| G A Mason, C H Walker, A J Prange, S C Bond. GABA uptake is inhibited by thyroid hormones: implications for depression. Psychoneuroendocrinology. vol 12. issue 1. 1987-06-26. PMID:2884685. |
gaba uptake is inhibited by thyroid hormones: implications for depression. |
1987-06-26 |
2023-08-11 |
rat |
| D I Kerr, J Ong, R H Prager, B D Gynther, D R Curti. Phaclofen: a peripheral and central baclofen antagonist. Brain research. vol 405. issue 1. 1987-06-08. PMID:3032346. |
phaclofen, the phosphonic acid derivative of baclofen, reversibly antagonized the depression of the cholinergic twitch response of the guinea pig ileum and distal colon by either baclofen or gaba. |
1987-06-08 |
2023-08-11 |
cat |
| J Ong, D I Kerr, G A Johnsto. Calcium dependence of baclofen- and GABA-induced depression of responses to transmural stimulation in the guinea-pig isolated ileum. European journal of pharmacology. vol 134. issue 3. 1987-05-28. PMID:2436928. |
both baclofen and gamma-aminobutyric acid (gaba) induced a dose-dependent depression of cholinergic twitch contractions in the transmurally stimulated guinea-pig isolated ileum. |
1987-05-28 |
2023-08-11 |
Not clear |
| S Sasaki, L C Lee, Y Nakamura, I Iyota, M Fukuyama, A Inoue, K Takeda, M Yoshimura, M Nakagawa, H Ijich. Hypotension and hypothalamic depression produced by intracerebroventricular injections of GABA in spontaneously hypertensive rats. Japanese circulation journal. vol 50. issue 11. 1987-04-10. PMID:3820527. |
hypotension and hypothalamic depression produced by intracerebroventricular injections of gaba in spontaneously hypertensive rats. |
1987-04-10 |
2023-08-11 |
rat |
| G K Kadyrov, E A Abdullaev. [GABA metabolism and the formation of a sensorimotor cortex evoked potential in the presence of excess zinc ions]. Biulleten' eksperimental'noi biologii i meditsiny. vol 103. issue 1. 1987-03-20. PMID:2879575. |
long-term (for 7, 14, 21 days) zncl2 administration at a dose of 0.1 mg/kg produced a sharp depression in the potential appearance and an increase in gaba content by 50% with the enhancement of glutamate decarboxylase activity and the attenuation of gaba-transaminase activity. |
1987-03-20 |
2023-08-11 |
Not clear |
| S C Gilman, J S Colton, J M Hallenbec. Effect of pressure on [3H]GABA release by synaptosomes isolated from cerebral cortex. Journal of applied physiology (Bethesda, Md. : 1985). vol 61. issue 6. 1987-03-11. PMID:3804914. |
the major observation was a 33% depression in total [3h]gaba efflux from depolarized cerebrocortical synaptosomes at 67.7 ata. |
1987-03-11 |
2023-08-11 |
Not clear |
| H J Little, D L Thoma. The effects of anaesthetics and high pressure on the responses of the rat superior cervical ganglion in vitro. The Journal of physiology. vol 374. 1986-10-23. PMID:3746696. |
it was concluded that there was no evidence that the basis of this interaction lay in the potentiation of gaba responses by general anaesthetics, or the depression of cholinergic responses, although the changes seen were not in all cases simply additive. |
1986-10-23 |
2023-08-11 |
mouse |
| S Giuliani, C A Maggi, A Mel. Differences in cardiovascular responses to peripherally administered GABA as influenced by basal conditions and type of anaesthesia. British journal of pharmacology. vol 88. issue 3. 1986-09-26. PMID:3742154. |
in picrotoxin pretreated animals anaesthetized with urethane, gaba produced an initial depression of cardiovascular parameters followed by an excitatory phase. |
1986-09-26 |
2023-08-11 |
Not clear |
| D I Kerr, J Ong, R H Prager, D A War. Caprolactam-barbiturate interaction at the GABAA receptor complex in the guinea-pig intestine. European journal of pharmacology. vol 124. issue 1-2. 1986-08-15. PMID:3013660. |
4,6,6-trimethylcaprolactam antagonised gabaa receptor-mediated contractile responses in guinea-pig isolated ileum, displacing the gaba dose-response curve to the right in a non-parallel manner, and causing a depression of the maximum response. |
1986-08-15 |
2023-08-11 |
Not clear |
| M P Kneussl, P Pappagianopoulos, B Hoop, H Kazem. Reversible depression of ventilation and cardiovascular function by ventriculocisternal perfusion with gamma-aminobutyric acid in dogs. The American review of respiratory disease. vol 133. issue 6. 1986-07-09. PMID:3717757. |
reversible depression of ventilation and cardiovascular function by ventriculocisternal perfusion with gamma-aminobutyric acid in dogs. |
1986-07-09 |
2023-08-11 |
Not clear |
| M P Kneussl, P Pappagianopoulos, B Hoop, H Kazem. Reversible depression of ventilation and cardiovascular function by ventriculocisternal perfusion with gamma-aminobutyric acid in dogs. The American review of respiratory disease. vol 133. issue 6. 1986-07-09. PMID:3717757. |
perfusion with mock csf alone restored cardiorespiratory depression caused by gaba. |
1986-07-09 |
2023-08-11 |
Not clear |
| T Dalkar. Nipecotic acid, an uptake blocker, prevents fading of the gamma-aminobutyric acid effect. Brain research. vol 366. issue 1-2. 1986-05-30. PMID:3008910. |
pyramidale caused a more prominent depression without fading, which suggests that removal of gaba, by uptake, can at least in part account for 'fading'. |
1986-05-30 |
2023-08-11 |
rat |
| D P Artemenko, V D Gerasimo. [Sensitivity to GABA of the soma and dendrites of pyramidal cells in isolated sections of hippocampus in the rat]. Neirofiziologiia = Neurophysiology. vol 17. issue 6. 1986-03-10. PMID:3003593. |
thiopental intensified the depression produced by gaba. |
1986-03-10 |
2023-08-11 |
rat |
| D R Stevens, J P Gallagher, P Shinnick-Gallaghe. Studies on the depression of gamma-aminobutyric acid potentials by phloridzin in cat dorsal root ganglion cells in vitro. Neuroscience letters. vol 60. issue 2. 1985-12-18. PMID:2997675. |
studies on the depression of gamma-aminobutyric acid potentials by phloridzin in cat dorsal root ganglion cells in vitro. |
1985-12-18 |
2023-08-11 |
cat |
| K G Lloyd, F Thuret, A Pil. Upregulation of gamma-aminobutyric acid (GABA) B binding sites in rat frontal cortex: a common action of repeated administration of different classes of antidepressants and electroshock. The Journal of pharmacology and experimental therapeutics. vol 235. issue 1. 1985-11-08. PMID:2995646. |
together with the rather sparse data in the literature on gaba in depression and antidepressant drug action, these findings support a common gabaergic mechanism of action of antidepressant drugs and electroshock, mediated via gaba b synapses. |
1985-11-08 |
2023-08-11 |
rat |
| G Bartholini, K G Lloyd, B Scatton, B Zivkovic, P L Morsell. The GABA hypothesis of depression and antidepressant drug action. Psychopharmacology bulletin. vol 21. issue 3. 1985-10-22. PMID:2994153. |
the gaba hypothesis of depression and antidepressant drug action. |
1985-10-22 |
2023-08-11 |
Not clear |