Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Michael R DeBaun, Allison A Kin. Prevention of central nervous system sequelae in sickle cell disease without evidence from randomized controlled trials: the case for a team-based learning collaborative. Hematology. American Society of Hematology. Education Program. vol 2016. issue 1. 2017-05-15. PMID:27913539. |
four common neurologic problems and strategies for management in children and adults with scd will be discussed: (1) secondary stroke prevention in high-income countries; (2) primary stroke prevention in low- and middle-income countries (lmics); (3) poor academic performance in students; and (4) cognitive disability in adults. |
2017-05-15 |
2023-08-13 |
Not clear |
Jamie M Kawadler, Jonathan D Clayden, Chris A Clark, Fenella J Kirkha. Intelligence quotient in paediatric sickle cell disease: a systematic review and meta-analysis. Developmental medicine and child neurology. vol 58. issue 7. 2017-04-27. PMID:27038278. |
sickle cell disease (scd) is the commonest cause of childhood stroke worldwide. |
2017-04-27 |
2023-08-13 |
Not clear |
Emilie Bollache, Nadjia Kachenoura, Roberto M Lang, Ankit A Desai, Victor Mor-Avi, Amit R Pate. Abnormalities in aortic properties: a potential link between left ventricular diastolic function and ventricular-aortic coupling in sickle cell disease. The international journal of cardiovascular imaging. vol 32. issue 6. 2017-04-24. PMID:26907920. |
compared to controls, scd patients had increased aortic diastolic area, global stroke volume, and both forward and backward flow, while aortic distensibility and peripheral blood pressure were similar. |
2017-04-24 |
2023-08-13 |
Not clear |
Eliyahu G Stoupe. Cosmic ray (neutron) activity and air pollution nanoparticles - cardiovascular disease risk factors - separate or together? Journal of basic and clinical physiology and pharmacology. vol 27. issue 5. 2017-04-18. PMID:27180339. |
in the last decade, a number of studies were published showing links between cardiovascular events such as stroke (cva), acute myocardial infarction (ami), sudden cardiac death (scd) and cosmic ray activity (cra) marker neutron activity on the earth's surface (imp/min). |
2017-04-18 |
2023-08-13 |
human |
Matthew T Borzage, Adam M Bush, Soyoung Choi, Aart J Nederveen, Lena Václavů, Thomas D Coates, John C Woo. Predictors of cerebral blood flow in patients with and without anemia. Journal of applied physiology (Bethesda, Md. : 1985). vol 120. issue 8. 2016-12-27. PMID:26796758. |
sickle cell disease (scd) is the most common cause of stroke in childhood and results primarily from a mismatch of cerebral oxygen supply and demand rather than arterial obstruction. |
2016-12-27 |
2023-08-13 |
human |
Li Wang, Luis E F Almeida, Celia M de Souza Batista, Alfia Khaibullina, Nuo Xu, Sarah Albani, Kira A Guth, Ji Sung Seo, Martha Quezado, Zenaide M N Quezad. Cognitive and behavior deficits in sickle cell mice are associated with profound neuropathologic changes in hippocampus and cerebellum. Neurobiology of disease. vol 85. 2016-09-21. PMID:26462816. |
strokes are perhaps the most serious complications of sickle cell disease (scd) and by the fifth decade occur in approximately 25% of patients. |
2016-09-21 |
2023-08-13 |
mouse |
Ziad Solh, Michael S Taccone, Samantha Marin, Uma Athale, Vicky R Breake. Neurological PRESentations in Sickle Cell Patients Are Not Always Stroke: A Review of Posterior Reversible Encephalopathy Syndrome in Sickle Cell Disease. Pediatric blood & cancer. vol 63. issue 6. 2016-08-19. PMID:26871763. |
acute neurological changes in sickle cell disease (scd) patients often raise the suspicion for stroke. |
2016-08-19 |
2023-08-13 |
Not clear |
Ziad Solh, Michael S Taccone, Samantha Marin, Uma Athale, Vicky R Breake. Neurological PRESentations in Sickle Cell Patients Are Not Always Stroke: A Review of Posterior Reversible Encephalopathy Syndrome in Sickle Cell Disease. Pediatric blood & cancer. vol 63. issue 6. 2016-08-19. PMID:26871763. |
we aimed to (i) review the pres literature in scd patients including clinical presentation, risk factors, pathophysiology, and management and (ii) elucidate the distinction between pres and stroke in scd. |
2016-08-19 |
2023-08-13 |
Not clear |
Ziad Solh, Michael S Taccone, Samantha Marin, Uma Athale, Vicky R Breake. Neurological PRESentations in Sickle Cell Patients Are Not Always Stroke: A Review of Posterior Reversible Encephalopathy Syndrome in Sickle Cell Disease. Pediatric blood & cancer. vol 63. issue 6. 2016-08-19. PMID:26871763. |
pres and stroke in scd are distinguishable conditions. |
2016-08-19 |
2023-08-13 |
Not clear |
Robert J Adam. Prevention of stroke in sickle cell anemia. The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics. vol 42. issue 2. 2016-07-06. PMID:25040376. |
the risk of stroke for a child with scd is many times greater than that of a healthy child without scd or heart disease. |
2016-07-06 |
2023-08-13 |
Not clear |
Michael R DeBaun, Fenella J Kirkha. Central nervous system complications and management in sickle cell disease. Blood. vol 127. issue 7. 2016-07-01. PMID:26758917. |
with advances in brain imaging and completion of randomized clinical trials (rcts) for primary and secondary stroke prevention, the natural history of central nervous system (cns) complications in sickle cell disease (scd) is evolving. |
2016-07-01 |
2023-08-13 |
Not clear |
Allison A King, Naynesh Kamani, Nancy Bunin, Indira Sahdev, Joel Brochstein, Robert J Hayashi, Michael Grimley, Allistair Abraham, Jacqueline Dioguardi, Ka Wah Chan, Dorothea Douglas, Roberta Adams, Martin Andreansky, Eric Anderson, Andrew Gilman, Sonali Chaudhury, Lolie Yu, Jignesh Dalal, Gregory Hale, Geoff Cuvelier, Akshat Jain, Jennifer Krajewski, Alfred Gillio, Kimberly A Kasow, David Delgado, Eric Hanson, Lisa Murray, Shalini Sheno. Successful matched sibling donor marrow transplantation following reduced intensity conditioning in children with hemoglobinopathies. American journal of hematology. vol 90. issue 12. 2016-06-02. PMID:26348869. |
all patients who engrafted were transfusion independent; no strokes or pulmonary complications of scd were noted, and pain symptoms subsided within 6 months posttransplant. |
2016-06-02 |
2023-08-13 |
Not clear |
Hyacinth I Hyacinth, Robert J Adams, Charles S Greenberg, Jenifer H Voeks, Allyson Hill, Jacqueline M Hibbert, Beatrice E Ge. Effect of Chronic Blood Transfusion on Biomarkers of Coagulation Activation and Thrombin Generation in Sickle Cell Patients at Risk for Stroke. PloS one. vol 10. issue 8. 2016-05-17. PMID:26305570. |
hypercoagulability in sickle cell disease (scd) is associated with multiple scd phenotypes, association with stroke risk has not been well described. |
2016-05-17 |
2023-08-13 |
human |
Hyacinth I Hyacinth, Robert J Adams, Charles S Greenberg, Jenifer H Voeks, Allyson Hill, Jacqueline M Hibbert, Beatrice E Ge. Effect of Chronic Blood Transfusion on Biomarkers of Coagulation Activation and Thrombin Generation in Sickle Cell Patients at Risk for Stroke. PloS one. vol 10. issue 8. 2016-05-17. PMID:26305570. |
biomarkers of coagulation activation/thrombin generation were significantly elevated in children with scd, at high risk for stroke. |
2016-05-17 |
2023-08-13 |
human |
Hyacinth I Hyacinth, Robert J Adams, Charles S Greenberg, Jenifer H Voeks, Allyson Hill, Jacqueline M Hibbert, Beatrice E Ge. Effect of Chronic Blood Transfusion on Biomarkers of Coagulation Activation and Thrombin Generation in Sickle Cell Patients at Risk for Stroke. PloS one. vol 10. issue 8. 2016-05-17. PMID:26305570. |
reduction in levels of these biomarkers correlated with reduction in stroke risk (lower tcd velocity), indicating a possible role for hypercoagulation in scd associated stroke. |
2016-05-17 |
2023-08-13 |
human |
Adnan I Qureshi, Ahmed A Malik, Malik M Adil, M Fareed K Sur. Oral contraceptive use and incident stroke in women with sickle cell disease. Thrombosis research. vol 136. issue 2. 2016-05-03. PMID:26140736. |
however, the effect is not studied in the stroke prone sickle cell disease (scd) population. |
2016-05-03 |
2023-08-13 |
Not clear |
Adnan I Qureshi, Ahmed A Malik, Malik M Adil, M Fareed K Sur. Oral contraceptive use and incident stroke in women with sickle cell disease. Thrombosis research. vol 136. issue 2. 2016-05-03. PMID:26140736. |
we want to determine the rate of incident stroke among women with scd enrolled in a large cohort with longitudinal follow-up. |
2016-05-03 |
2023-08-13 |
Not clear |
Charlotte Baker, Althea M Grant, Mary G George, Scott D Grosse, Thomas V Adamkiewic. Contribution of Sickle Cell Disease to the Pediatric Stroke Burden Among Hospital Discharges of African-Americans-United States, 1997-2012. Pediatric blood & cancer. vol 62. issue 12. 2016-02-08. PMID:26174777. |
approximately 10-20% of children with sickle cell disease (scd) develop stroke, but few consistent national estimates of the stroke burden for children with scd exist. |
2016-02-08 |
2023-08-13 |
Not clear |
Charlotte Baker, Althea M Grant, Mary G George, Scott D Grosse, Thomas V Adamkiewic. Contribution of Sickle Cell Disease to the Pediatric Stroke Burden Among Hospital Discharges of African-Americans-United States, 1997-2012. Pediatric blood & cancer. vol 62. issue 12. 2016-02-08. PMID:26174777. |
the purpose of this study is to determine the proportion of diagnosed stroke among african-american pediatric discharges with and without scd. |
2016-02-08 |
2023-08-13 |
Not clear |
A Dorie, A Guindo, Y S Saro, B A Touré, B Fané, A K Dembelé, D A Diall. [Screening of cerebral vasculopathy in sickle cell anemia children using transcranial Doppler]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie. vol 22. issue 3. 2015-12-28. PMID:25636211. |
transcranial doppler (tcd) ultrasonography used to identify scd patients at risk of stroke may contribute to significantly reducing morbidity and mortality in these patients by indicating appropriate treatment. |
2015-12-28 |
2023-08-13 |
Not clear |