| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eboni I Lance, Emily Barron-Casella, Allen D Everett, James F Casell. Brain-derived neurotrophic factor levels in pediatric sickle cell disease. Pediatric blood & cancer. vol 67. issue 2. 2020-04-22. PMID:31736231. |
children with sickle cell disease (scd) have an increased risk of neurological complications, particularly stroke and silent cerebral infarction (sci). |
2020-04-22 |
2023-08-13 |
human |
| Eboni I Lance, Emily Barron-Casella, Allen D Everett, James F Casell. Brain-derived neurotrophic factor levels in pediatric sickle cell disease. Pediatric blood & cancer. vol 67. issue 2. 2020-04-22. PMID:31736231. |
brain-derived neurotrophic factor (bdnf) is a nerve growth factor associated with neuronal survival, synaptic plasticity, elevated transcranial doppler (tcd) velocities and increased risk of stroke in patients with scd. |
2020-04-22 |
2023-08-13 |
human |
| Allison A King, Robert C McKinstry, Juan Wu, Mary Eapen, Regina Abel, Taniya Varughese, Naynesh Kamani, Shalini Sheno. Functional and Radiologic Assessment of the Brain after Reduced-Intensity Unrelated Donor Transplantation for Severe Sickle Cell Disease: Blood and Marrow Transplant Clinical Trials Network Study 0601. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. vol 25. issue 5. 2020-03-20. PMID:30639825. |
stroke and cognitive decline are hallmarks of sickle cell disease (scd). |
2020-03-20 |
2023-08-13 |
human |
| Jifang Zhou, Jin Han, Edith A Nutescu, William L Galanter, Surrey M Walton, Victor R Gordeuk, Santosh L Saraf, Gregory S Cali. Similar burden of type 2 diabetes among adult patients with sickle cell disease relative to African Americans in the U.S. population: a six-year population-based cohort analysis. British journal of haematology. vol 185. issue 1. 2020-02-19. PMID:30714090. |
compared to scd patients without t2dm, more scd patients with t2dm had diagnoses of nephropathy (28·0% vs. 9·5%; p < 0·001), neuropathy (17·7% vs. 5·2%; p < 0·001) and stroke (24·1% vs. 9·2%; p < 0·001). |
2020-02-19 |
2023-08-13 |
Not clear |
| Anna T Murphy, Stella Kravtsov, Morgan Sangeux, Barry Rawicki, Peter W Ne. Utilizing three dimensional clinical gait analysis to optimize mobility outcomes in incomplete spinal cord damage. Gait & posture. vol 74. 2020-01-23. PMID:31446333. |
three-dimensional gait analysis (3dga) has not previously been considered by consensus panels of spinal cord experts for use in studies of patients with spinal cord damage (scd), yet it is frequently used in other neurological populations, such as stroke and cerebral palsy. |
2020-01-23 |
2023-08-13 |
Not clear |
| Kristin P Guilliams, Fenella J Kirkham, Susanne Holzhauer, Steven Pavlakis, Bryan Philbrook, Catherine Amlie-Lefond, Michael J Noetzel, Nomazulu Dlamini, Mukta Sharma, Jessica L Carpenter, Christine K Fox, Marcela Torres, Rebecca N Ichord, Lori C Jordan, Michael M Dowlin. Arteriopathy Influences Pediatric Ischemic Stroke Presentation, but Sickle Cell Disease Influences Stroke Management. Stroke. vol 50. issue 5. 2020-01-08. PMID:31009343. |
background and purpose- sickle cell disease (scd) and arteriopathy are pediatric stroke risk factors that are not mutually exclusive. |
2020-01-08 |
2023-08-13 |
Not clear |
| Kristin P Guilliams, Fenella J Kirkham, Susanne Holzhauer, Steven Pavlakis, Bryan Philbrook, Catherine Amlie-Lefond, Michael J Noetzel, Nomazulu Dlamini, Mukta Sharma, Jessica L Carpenter, Christine K Fox, Marcela Torres, Rebecca N Ichord, Lori C Jordan, Michael M Dowlin. Arteriopathy Influences Pediatric Ischemic Stroke Presentation, but Sickle Cell Disease Influences Stroke Management. Stroke. vol 50. issue 5. 2020-01-08. PMID:31009343. |
we hypothesized that despite similarities in clinical presentation and radiographic appearance of arteriopathies, stroke evaluation and management differ in children with scd compared with those without scd. |
2020-01-08 |
2023-08-13 |
Not clear |
| Kristin P Guilliams, Fenella J Kirkham, Susanne Holzhauer, Steven Pavlakis, Bryan Philbrook, Catherine Amlie-Lefond, Michael J Noetzel, Nomazulu Dlamini, Mukta Sharma, Jessica L Carpenter, Christine K Fox, Marcela Torres, Rebecca N Ichord, Lori C Jordan, Michael M Dowlin. Arteriopathy Influences Pediatric Ischemic Stroke Presentation, but Sickle Cell Disease Influences Stroke Management. Stroke. vol 50. issue 5. 2020-01-08. PMID:31009343. |
methods- we compared presentation and management of children with and without scd enrolled in the ipss (international pediatric stroke study) with acute arterial ischemic stroke, according to scd and arteriopathy status. |
2020-01-08 |
2023-08-13 |
Not clear |
| Kristin P Guilliams, Fenella J Kirkham, Susanne Holzhauer, Steven Pavlakis, Bryan Philbrook, Catherine Amlie-Lefond, Michael J Noetzel, Nomazulu Dlamini, Mukta Sharma, Jessica L Carpenter, Christine K Fox, Marcela Torres, Rebecca N Ichord, Lori C Jordan, Michael M Dowlin. Arteriopathy Influences Pediatric Ischemic Stroke Presentation, but Sickle Cell Disease Influences Stroke Management. Stroke. vol 50. issue 5. 2020-01-08. PMID:31009343. |
conclusions- arteriopathy, and not scd status, was most influential of stroke presentation. |
2020-01-08 |
2023-08-13 |
Not clear |
| Kristin P Guilliams, Fenella J Kirkham, Susanne Holzhauer, Steven Pavlakis, Bryan Philbrook, Catherine Amlie-Lefond, Michael J Noetzel, Nomazulu Dlamini, Mukta Sharma, Jessica L Carpenter, Christine K Fox, Marcela Torres, Rebecca N Ichord, Lori C Jordan, Michael M Dowlin. Arteriopathy Influences Pediatric Ischemic Stroke Presentation, but Sickle Cell Disease Influences Stroke Management. Stroke. vol 50. issue 5. 2020-01-08. PMID:31009343. |
however, scd status influenced stroke management because children with scd were less likely to have echocardiograms or receive antithrombotic therapy. |
2020-01-08 |
2023-08-13 |
Not clear |
| Yasmeen Akhtar Haseeb, Nourah Hasan Al Qahtan. Outcome of Pregnancy in Saudi Women with Sickle Cell Disease Attending the Tertiary Care University Hospital in Eastern Province of Saudi Arabia. African journal of reproductive health. vol 23. issue 3. 2019-12-31. PMID:31782630. |
hypertensive disorders (13.3%), abruptio placenta (1.6%), intrauterine growth restriction (19.2%), thromboembolism (6.6%) and stroke (2.6%) were all higher in scd as compared to the control group .the complications of scd itself including anemia (89.4%), acute chest syndrome (13.2%) and sickle cell crisis (39.2%) were also increased during the pregnancy. |
2019-12-31 |
2023-08-13 |
Not clear |
| Michelle Case, Sina Shirinpour, Vishal Vijayakumar, Huishi Zhang, Yvonne Datta, Stephen Nelson, Paola Pergami, Deepika S Darbari, Kalpna Gupta, Bin H. Graph theory analysis reveals how sickle cell disease impacts neural networks of patients with more severe disease. NeuroImage. Clinical. vol 21. 2019-12-26. PMID:30477765. |
sickle cell disease (scd) is a hereditary blood disorder associated with many life-threatening comorbidities including cerebral stroke and chronic pain. |
2019-12-26 |
2023-08-13 |
Not clear |
| Hyacinth I Hyacinth, Courtney L Sugihara, Thomas L Spencer, David R Archer, Andy Y Shi. Higher prevalence of spontaneous cerebral vasculopathy and cerebral infarcts in a mouse model of sickle cell disease. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 39. issue 2. 2019-12-23. PMID:28925802. |
stroke is a dramatic complication of sickle cell disease (scd), which is associated with cerebral vasculopathies including moya moya, intravascular thrombi, cerebral hyperemia, and increased vessel tortuosity. |
2019-12-23 |
2023-08-13 |
mouse |
| Yaqiong Chai, Adam M Bush, Julie Coloigner, Aart J Nederveen, Benita Tamrazi, Chau Vu, Soyoung Choi, Thomas D Coates, Natasha Lepore, John C Woo. White matter has impaired resting oxygen delivery in sickle cell patients. American journal of hematology. vol 94. issue 4. 2019-12-20. PMID:30697803. |
although modern medical management has lowered overt stroke occurrence in patients with sickle cell disease (scd), progressive white matter (wm) damage remains common. |
2019-12-20 |
2023-08-13 |
human |
| Marianne E McPherson Yee, Erin K Meyer, Ross M Fasano, Peter A Lane, Cassandra D Josephson, Angela G Breg. Health literacy and knowledge of chronic transfusion therapy in adolescents with sickle cell disease and caregivers. Pediatric blood & cancer. vol 66. issue 7. 2019-12-17. PMID:30941859. |
patients with sickle cell disease (scd) may require chronic transfusion therapy (ctt) for prevention of stroke or other complications. |
2019-12-17 |
2023-08-13 |
Not clear |
| Eric J Niesor, Renée Benghozi, Philippe Amouyel, Keith C Ferdinand, Gregory G Schwart. Adenylyl Cyclase 9 Polymorphisms Reveal Potential Link to HDL Function and Cardiovascular Events in Multiple Pathologies: Potential Implications in Sickle Cell Disease. Cardiovascular drugs and therapy. vol 29. issue 6. 2019-11-20. PMID:26619842. |
moreover, adcy9 polymorphism is associated with risk of stroke in scd. |
2019-11-20 |
2023-08-13 |
Not clear |
| Caterina P Minniti, Vinod K Gidvani, Dorothy Bulas, Wendy A Brown, Gilbert Vezina, M Catherine Driscol. Transcranial Doppler Changes in Children With Sickle Cell Disease on Transfusion Therapy. Journal of pediatric hematology/oncology. vol 26. issue 10. 2019-11-20. PMID:27811602. |
transcranial doppler (tcd) is an effective method for screening patients with sickle cell disease (scd) at risk for first stroke. |
2019-11-20 |
2023-08-13 |
Not clear |
| Michelle Downes, Fenella J Kirkham, Paul T Telfer, Michelle de Haa. Altered Neurophysiological Processing of Auditory Attention in Preschool Children With Sickle Cell Disease. Journal of pediatric psychology. vol 43. issue 8. 2019-11-15. PMID:29048550. |
sickle cell disease (scd) is a genetic red blood cell disorder that often leads to stroke and executive dysfunction in school-age children and adults. |
2019-11-15 |
2023-08-13 |
Not clear |
| IkeOluwa Lagunju, B J Brown, A O Oyinlade, A Asinobi, J Ibeh, A Esione, O O Sodeind. Annual stroke incidence in Nigerian children with sickle cell disease and elevated TCD velocities treated with hydroxyurea. Pediatric blood & cancer. vol 66. issue 3. 2019-11-12. PMID:29797633. |
elevated transcranial doppler (tcd) velocities accurately predict stroke risk in children with sickle cell disease (scd). |
2019-11-12 |
2023-08-13 |
Not clear |
| Kenzaburo Nakajima, Takeshi Aiba, Takeru Makiyama, Suguru Nishiuchi, Seiko Ohno, Koichi Kato, Yuta Yamamoto, Takahiro Doi, Satoshi Shizuta, Kenji Onoue, Nobue Yagihara, Taisuke Ishikawa, Ichiro Watanabe, Hiroshi Kawakami, Yasushi Oginosawa, Nobuyuki Murakoshi, Akihiko Nogami, Kazutaka Aonuma, Yoshihiko Saito, Takeshi Kimura, Satoshi Yasuda, Naomasa Makita, Wataru Shimizu, Minoru Horie, Kengo Kusan. Clinical Manifestations and Long-Term Mortality in Lamin A/C Mutation Carriers From a Japanese Multicenter Registry. Circulation journal : official journal of the Japanese Circulation Society. vol 82. issue 11. 2019-11-12. PMID:30078822. |
furthermore, during follow-up, 17 patients died: 12 end-stage heart failure, 4 scd and 1 stroke. |
2019-11-12 |
2023-08-13 |
human |