| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Boe-Eun Kim, Jeong-Hwa Lee, Ho-Shik Kim, Oh-Joo Kwon, Seong-Whan Jeong, In-Kyung Ki. Involvement of Sox-4 in the cytochrome c-dependent AIF-independent apoptotic pathway in HeLa cells induced by Delta12-prostaglandin J2. Experimental & molecular medicine. vol 36. issue 5. 2005-04-26. PMID:15557816. |
previous study showed delta(12)-pgj(2)-induced apoptosis utilized caspase cascade through cytochrome c-dependent pathways in hela cells. |
2005-04-26 |
2023-08-12 |
Not clear |
| Boe-Eun Kim, Jeong-Hwa Lee, Ho-Shik Kim, Oh-Joo Kwon, Seong-Whan Jeong, In-Kyung Ki. Involvement of Sox-4 in the cytochrome c-dependent AIF-independent apoptotic pathway in HeLa cells induced by Delta12-prostaglandin J2. Experimental & molecular medicine. vol 36. issue 5. 2005-04-26. PMID:15557816. |
in this study, the cellular mechanism of delta(12)-pgj(2)- induced apoptosis in hela cells, specifically, the role of two mitochondrial factors; bcl-2 and apoptosis-inducing factor (aif) was investigated. |
2005-04-26 |
2023-08-12 |
Not clear |
| Boe-Eun Kim, Jeong-Hwa Lee, Ho-Shik Kim, Oh-Joo Kwon, Seong-Whan Jeong, In-Kyung Ki. Involvement of Sox-4 in the cytochrome c-dependent AIF-independent apoptotic pathway in HeLa cells induced by Delta12-prostaglandin J2. Experimental & molecular medicine. vol 36. issue 5. 2005-04-26. PMID:15557816. |
pre-treatment of z-vad- fmk, the pan-caspase inhibitor, resulted in the attenuation of ym depolarization in delta(12)-pgj(2)-induced apoptosis. |
2005-04-26 |
2023-08-12 |
Not clear |
| Boe-Eun Kim, Jeong-Hwa Lee, Ho-Shik Kim, Oh-Joo Kwon, Seong-Whan Jeong, In-Kyung Ki. Involvement of Sox-4 in the cytochrome c-dependent AIF-independent apoptotic pathway in HeLa cells induced by Delta12-prostaglandin J2. Experimental & molecular medicine. vol 36. issue 5. 2005-04-26. PMID:15557816. |
these and previous findings together suggest that delta(12)-pgj(2)-induced apoptosis in hela cells is caspase-dependent, aif-independent events which may be affected by sox-4 protein expression up-regulated by delta(12)-pgj(2). |
2005-04-26 |
2023-08-12 |
Not clear |
| Lihong Yin, Nabila Bennani-Baiti, C Thomas Powel. Phorbol ester-induced apoptosis of C4-2 cells requires both a unique and a redundant protein kinase C signaling pathway. The Journal of biological chemistry. vol 280. issue 7. 2005-04-18. PMID:15611126. |
previous reports have implicated activation of protein kinase c (pkc) isozymes alpha and delta in pma-induced lncap apoptosis using overexpression, pharmacological inhibitors, and dominant-negative constructs, but have left unresolved if other isozymes are involved, if there are separate requirements for individual pkc isozymes, or if there is redundancy. |
2005-04-18 |
2023-08-12 |
human |
| J Eeva, J Pelkone. Mechanisms of B cell receptor induced apoptosis. Apoptosis : an international journal on programmed cell death. vol 9. issue 5. 2005-04-12. PMID:15314280. |
based on recent studies, collapse of mitochondrial membrane potential (delta psi m) seems to be an essential event for bcr-mediated apoptosis in both mature and immature cells. |
2005-04-12 |
2023-08-12 |
Not clear |
| Catherine Sweeney, David Morrow, Yvonne A Birney, Seamus Coyle, Colm Hennessy, Agnieszka Scheller, Philip M Cummins, Dermot Walls, Eileen M Redmond, Paul A Cahil. Notch 1 and 3 receptor signaling modulates vascular smooth muscle cell growth, apoptosis, and migration via a CBF-1/RBP-Jk dependent pathway. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 18. issue 12. 2005-04-05. PMID:15247148. |
moreover, inhibition of endogenous notch mediated cbf-1/rbp-jk regulated gene expression with a non-dna binding mutant of cbf-1, a notch ic deleted of its delta ram domain and the epstein-barr virus encoded rpms-1, in conjunction with pharmacological inhibitors of notch ic receptor trafficking (brefeldin a and monensin), resulted in a significant decrease in cell growth while concomitantly increasing smc apoptosis and migration. |
2005-04-05 |
2023-08-12 |
Not clear |
| E Simeonova, M Garstka, J Kozioł-Lipińska, A Mostowsk. Monitoring the mitochondrial transmembrane potential with the JC-1 fluorochrome in programmed cell death during mesophyll leaf senescence. Protoplasma. vol 223. issue 2-4. 2005-03-04. PMID:15221519. |
we stated that the reduction of delta psi(m) does not directly induce programmed cell death in mesophyll cells, as opposed to animal apoptosis. |
2005-03-04 |
2023-08-12 |
Not clear |
| Hideki Mizutani, Saeko Tada-Oikawa, Yusuke Hiraku, Michio Kojima, Shosuke Kawanish. Mechanism of apoptosis induced by doxorubicin through the generation of hydrogen peroxide. Life sciences. vol 76. issue 13. 2005-03-01. PMID:15680309. |
this oxidative dna damage causes indirect h(2)o(2) generation through parp and nad(p)h oxidase activation, leading to the delta psi m increase and subsequent caspase-3 activation in dox-induced apoptosis. |
2005-03-01 |
2023-08-12 |
human |
| Masashi Kitazawa, Vellareddy Anantharam, Yongjie Yang, Yoko Hirata, Arthi Kanthasamy, Anumantha G Kanthasam. Activation of protein kinase C delta by proteolytic cleavage contributes to manganese-induced apoptosis in dopaminergic cells: protective role of Bcl-2. Biochemical pharmacology. vol 69. issue 1. 2005-02-15. PMID:15588722. |
activation of protein kinase c delta by proteolytic cleavage contributes to manganese-induced apoptosis in dopaminergic cells: protective role of bcl-2. |
2005-02-15 |
2023-08-12 |
Not clear |
| Giuseppina Colonna-Romano, Alessandra Aquino, Matteo Bulati, Domenico Lio, Giuseppina Candore, Gioacchino Oddo, Giuseppe Scialabba, Salvatore Vitello, Calogero Carus. Impairment of gamma/delta T lymphocytes in elderly: implications for immunosenescence. Experimental gerontology. vol 39. issue 10. 2005-02-03. PMID:15501013. |
moreover, we demonstrate that gamma delta t cells in aged and centenarians show an enhanced sensitivity to undergo apoptosis induced both by alpha-fas and tnf-alpha. |
2005-02-03 |
2023-08-12 |
human |
| Giuseppina Colonna-Romano, Alessandra Aquino, Matteo Bulati, Domenico Lio, Giuseppina Candore, Gioacchino Oddo, Giuseppe Scialabba, Salvatore Vitello, Calogero Carus. Impairment of gamma/delta T lymphocytes in elderly: implications for immunosenescence. Experimental gerontology. vol 39. issue 10. 2005-02-03. PMID:15501013. |
all together these data suggest that gamma delta t lymphocytes are impaired in elderly and suggest that the reduced ability to proliferate and the reduced number of circulating gamma delta t lymphocytes is due to the proneness to apoptosis. |
2005-02-03 |
2023-08-12 |
human |
| José M López, Manuel A Fernández, Maria Piqué, Joan Gi. Aspirin-induced apoptosis in jurkat cells is not mediated by peroxisome proliferator-activated receptor delta. Molecular and cellular biochemistry. vol 266. issue 1-2. 2005-02-03. PMID:15646027. |
aspirin-induced apoptosis in jurkat cells is not mediated by peroxisome proliferator-activated receptor delta. |
2005-02-03 |
2023-08-12 |
Not clear |
| José M López, Manuel A Fernández, Maria Piqué, Joan Gi. Aspirin-induced apoptosis in jurkat cells is not mediated by peroxisome proliferator-activated receptor delta. Molecular and cellular biochemistry. vol 266. issue 1-2. 2005-02-03. PMID:15646027. |
nonsteroidal antiinflammatory drugs may induce apoptosis via inhibition of peroxisome proliferator-activated receptor delta (ppardelta) activity. |
2005-02-03 |
2023-08-12 |
Not clear |
| Yulong L Chen, P Y Law, Horace H Lo. Inhibition of akt/protein kinase B signaling by naltrindole in small cell lung cancer cells. Cancer research. vol 64. issue 23. 2005-01-27. PMID:15574783. |
here we report that naltrindole, which has been used as a classic delta opioid antagonist, inhibited growth and induced apoptosis in the three characteristic sclc cell lines, nci-h69, nci-h345, and nci-h510. |
2005-01-27 |
2023-08-12 |
Not clear |
| G M Leinninger, J W Russell, C M van Golen, A Berent, E L Feldma. Insulin-like growth factor-I regulates glucose-induced mitochondrial depolarization and apoptosis in human neuroblastoma. Cell death and differentiation. vol 11. issue 8. 2005-01-26. PMID:15105834. |
these results suggest that elevated glucose produces early initiator caspase activation, followed by delta psi(m) changes, in neuroblastoma cells; in turn, igf-i prevents apoptosis by preventing downstream caspase activation, maintaining delta psi(m) and regulating bcl proteins. |
2005-01-26 |
2023-08-12 |
human |
| Ji-Yeon Jung, Won-Jae Ki. Involvement of mitochondrial- and Fas-mediated dual mechanism in CoCl2-induced apoptosis of rat PC12 cells. Neuroscience letters. vol 371. issue 2-3. 2005-01-25. PMID:15519734. |
the main mechanism for these apoptosis appeared to be mitochondria-mediated pathway accompanied with loss of the mitochondrial transmembrane potential (delta psi m) followed by cytochrome c release from the mitochondria into the cytosol, resulting in the activation of caspase-9 and caspase-3. |
2005-01-25 |
2023-08-12 |
rat |
| Zheng-Guo Cui, Takashi Kondo, Ryohei Ogawa, Loreto B Feril, Qing-Li Zhao, Shigehito Wada, Toshiyuki Arai, Keisuke Makin. Enhancement of radiation-induced apoptosis by 6-formylpterin. Free radical research. vol 38. issue 4. 2004-10-21. PMID:15190933. |
these results indicate that intracellular h2o2 generated by 6-fp enhances radiation-induced apoptosis via the mitochondria-mediated caspase-dependent pathway, with the active involvement of pkc delta. |
2004-10-21 |
2023-08-12 |
human |
| Kazumasa Ohta, Rintarou Okoshi, Maiko Wakabayashi, Yutaka Sato, Harutoshi Kizak. Modulation of dexamethasone-induced thymocyte apoptosis by heat-shock protein 90-binding agents. The Bulletin of Tokyo Dental College. vol 45. issue 1. 2004-10-21. PMID:15346879. |
the present study showed that the hsp90-binding agents, geldanamycin, herbimycin a and radicicol, inhibited the murine thymocyte apoptosis induced by dexamethasone and was accompanied by the inhibition of the reduction of the mitochondrial transmembrane potential (delta psi m). |
2004-10-21 |
2023-08-12 |
Not clear |
| Yoonkyung Do, Robert J McKallip, Mitzi Nagarkatti, Prakash S Nagarkatt. Activation through cannabinoid receptors 1 and 2 on dendritic cells triggers NF-kappaB-dependent apoptosis: novel role for endogenous and exogenous cannabinoids in immunoregulation. Journal of immunology (Baltimore, Md. : 1950). vol 173. issue 4. 2004-09-28. PMID:15294950. |
addition of delta(9)-tetrahydrocannabinol (thc), a major psychoactive component found in marijuana or anandamide, an endogenous cannabinoid, to dc cultures induced apoptosis in dcs. |
2004-09-28 |
2023-08-12 |
mouse |