| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Leonid A Sitailo, Shalini S Tibudan, Mitchell F Dennin. Bax activation and induction of apoptosis in human keratinocytes by the protein kinase C delta catalytic domain. The Journal of investigative dermatology. vol 123. issue 3. 2004-09-20. PMID:15304079. |
bax activation and induction of apoptosis in human keratinocytes by the protein kinase c delta catalytic domain. |
2004-09-20 |
2023-08-12 |
human |
| Soon Young Shin, Chang Gun Kim, Jesang Ko, Do Sik Min, Jong-Soo Chang, Motoi Ohba, Toshio Kuroki, Young Bong Choi, Young-Ho Kim, Doe Sun Na, Jin Woo Kim, Young Han Le. Transcriptional and post-transcriptional regulation of the PKC delta gene by etoposide in L1210 murine leukemia cells: implication of PKC delta autoregulation. Journal of molecular biology. vol 340. issue 4. 2004-08-03. PMID:15223313. |
protein kinase c delta (pkc delta) plays an important role in the regulation of apoptosis in response to diverse anticancer agents. |
2004-08-03 |
2023-08-12 |
mouse |
| D Poncet, P Boya, D Métivier, N Zamzami, G Kroeme. Cytofluorometric quantitation of apoptosis-driven inner mitochondrial membrane permeabilization. Apoptosis : an international journal on programmed cell death. vol 8. issue 5. 2004-06-11. PMID:14601558. |
this decrease can be quantified by cytofluorometry and can be dissociated from other apoptosis-associated mitochondrial perturbations such as the loss of the mitochondrial transmembrane potential (delta phi m), the local overproduction of re-active oxygen species, and the mitochondrial release of cytochrome c. in some paradigms of apoptosis the loss of calcein/co2+ (cc) staining can be dissociated from the delta phi m loss, both of which may occur in a caspase-dependent or caspase-independent fashion, depending on the apoptosis inducer. |
2004-06-11 |
2023-08-12 |
Not clear |
| D Poncet, P Boya, D Métivier, N Zamzami, G Kroeme. Cytofluorometric quantitation of apoptosis-driven inner mitochondrial membrane permeabilization. Apoptosis : an international journal on programmed cell death. vol 8. issue 5. 2004-06-11. PMID:14601558. |
importantly, inner membrane permeabilization to cc may occur without a permanent delta phi m dissipation in apoptosis, suggesting that transient permeabilization events could participate at the apoptotic cascade. |
2004-06-11 |
2023-08-12 |
Not clear |
| John G Shelton, Fumin Chang, John T Lee, Richard A Franklin, Linda S Steelman, James A McCubre. B-raf and insulin synergistically prevent apoptosis and induce cell cycle progression in hematopoietic cells. Cell cycle (Georgetown, Tex.). vol 3. issue 2. 2004-05-21. PMID:14712088. |
apoptosis was prevented in fd/(delta)b-raf:er cells when they were cultured in the presence of il-3 or beta-estradiol, whereas they underwent apoptosis in their absence. |
2004-05-21 |
2023-08-12 |
Not clear |
| Bo-Eun Kim, Sung Rae Roh, Jin Woo Kim, Seong-Whan Jeong, In-Kyung Ki. Cytochrome C-dependent Fas-independent apoptotic pathway in HeLa cells induced by delta12-prostaglandin J2. Experimental & molecular medicine. vol 35. issue 4. 2004-05-06. PMID:14508070. |
particularly, 9-deoxy-delta(9,12)-13,14-dihydro pgd(2) (delta(12)-pgj(2)) was reported for its antineoplastic and apoptotic effects on various cancer cells, but its mechanism inducing apoptosis is still not clear. |
2004-05-06 |
2023-08-12 |
Not clear |
| Bo-Eun Kim, Sung Rae Roh, Jin Woo Kim, Seong-Whan Jeong, In-Kyung Ki. Cytochrome C-dependent Fas-independent apoptotic pathway in HeLa cells induced by delta12-prostaglandin J2. Experimental & molecular medicine. vol 35. issue 4. 2004-05-06. PMID:14508070. |
in this study, we have characterized apoptosis induced by delta(12)-pgj(2) in hela cells. |
2004-05-06 |
2023-08-12 |
Not clear |
| Bo-Eun Kim, Sung Rae Roh, Jin Woo Kim, Seong-Whan Jeong, In-Kyung Ki. Cytochrome C-dependent Fas-independent apoptotic pathway in HeLa cells induced by delta12-prostaglandin J2. Experimental & molecular medicine. vol 35. issue 4. 2004-05-06. PMID:14508070. |
treatment of delta(12)-pgj(2) induced apoptosis as indicated by dna fragmentation, chromatin condensation, and formation of apoptotic body. |
2004-05-06 |
2023-08-12 |
Not clear |
| Bo-Eun Kim, Sung Rae Roh, Jin Woo Kim, Seong-Whan Jeong, In-Kyung Ki. Cytochrome C-dependent Fas-independent apoptotic pathway in HeLa cells induced by delta12-prostaglandin J2. Experimental & molecular medicine. vol 35. issue 4. 2004-05-06. PMID:14508070. |
however, protein expression level of bcl-2 family was not altered by delta(12)-pgj(2), seems to have no effect on hela cell apoptosis. |
2004-05-06 |
2023-08-12 |
Not clear |
| Bo-Eun Kim, Sung Rae Roh, Jin Woo Kim, Seong-Whan Jeong, In-Kyung Ki. Cytochrome C-dependent Fas-independent apoptotic pathway in HeLa cells induced by delta12-prostaglandin J2. Experimental & molecular medicine. vol 35. issue 4. 2004-05-06. PMID:14508070. |
taken together, our results suggest that delta(12)-pgj(2)-induced apoptosis in hela cell utilized caspase cascade without fas receptor-ligand interaction and accompanied with nf-kappab inactivation. |
2004-05-06 |
2023-08-12 |
Not clear |
| Minoo D F Askari, Tuan Vo-Din. Implication of mitochondrial involvement in apoptotic activity of fragile histidine triad gene: application of synchronous luminescence spectroscopy. Biopolymers. vol 73. issue 4. 2004-04-15. PMID:14991669. |
the loss of delta psi(m) is greatly restricted in the presence of the apoptotic inhibitor, cyclosporin a. cytoplasmic translocation of cytochrome c in the fhit expressing cells as an early event in apoptosis is also demonstrated. |
2004-04-15 |
2023-08-12 |
human |
| Sushil K Sharma, Edward C Carlson, Manuchair Ebad. Neuroprotective actions of Selegiline in inhibiting 1-methyl, 4-phenyl, pyridinium ion (MPP+)-induced apoptosis in SK-N-SH neurons. Journal of neurocytology. vol 32. issue 4. 2004-04-14. PMID:14724376. |
mpp(+)-induced apoptosis was characterized by spherical appearance, suppressed neuritogenesis, phosphatidyl serine externalization, plasma membrane perforations, mitochondrial membrane potential (delta psi) collapse, mitochondrial aggregation, and nuclear dna fragmentation and condensation. |
2004-04-14 |
2023-08-12 |
Not clear |
| Ralf Schmidmaier, Mark Oellerich, Joachim Baumgart, Bertold Emmerich, Gerold Meinhard. Treosulfan-induced apoptosis in acute myeloid leukemia cells is accompanied by translocation of protein kinase C delta and enhanced by bryostatin-1. Experimental hematology. vol 32. issue 1. 2004-02-26. PMID:14725904. |
treosulfan-induced apoptosis in acute myeloid leukemia cells is accompanied by translocation of protein kinase c delta and enhanced by bryostatin-1. |
2004-02-26 |
2023-08-12 |
Not clear |
| Tomohide Mukogawa, Fumikazu Koyama, Masaaki Tachibana, Atsushi Takayanagi, Nobuyoshi Shimizu, Hisao Fujii, Masato Ueno, Hiroshi Matsumoto, Taku Takeuchi, Yoshiyuki Nakajim. Adenovirus-mediated gene transduction of truncated I kappa B alpha enhances radiosensitivity in human colon cancer cells. Cancer science. vol 94. issue 8. 2004-02-24. PMID:12901803. |
furthermore, it was demonstrated that apoptosis was increased by adenovirus-mediated gene transduction of i kappa b alpha delta n in vitro and in vivo. |
2004-02-24 |
2023-08-12 |
mouse |
| J H Jeng, Y J Wang, W H Chang, H L Wu, C H Li, B J Uang, J J Kang, J J Lee, L J Hahn, B R Lin, M C Chan. Reactive oxygen species are crucial for hydroxychavicol toxicity toward KB epithelial cells. Cellular and molecular life sciences : CMLS. vol 61. issue 1. 2004-02-24. PMID:14704856. |
hc-induced apoptosis and cell cycle arrest are associated with mitochondrial membrane potential (delta psim) depolarization as revealed by a decrease in rhodamine fluorescence. |
2004-02-24 |
2023-08-12 |
Not clear |
| Ushio Kikkawa, Hidenori Matsuzaki, Toshiyoshi Yamamot. Protein kinase C delta (PKC delta): activation mechanisms and functions. Journal of biochemistry. vol 132. issue 6. 2004-02-19. PMID:12473183. |
various lines of evidence indicate that pkc delta activated in distinct ways plays critical roles in cellular functions such as the control of growth, differentiation, and apoptosis. |
2004-02-19 |
2023-08-12 |
Not clear |
| Christian Benno Oberdanner, Tobias Kiesslich, Barbara Krammer, Kristjan Plaetze. Glucose is required to maintain high ATP-levels for the energy-utilizing steps during PDT-induced apoptosis. Photochemistry and photobiology. vol 76. issue 6. 2004-01-21. PMID:12511053. |
because the mitochondrial membrane potential (delta psi) decreases early in apoptosis, we raised the question about the mechanisms of maintaining a sufficiently high atp level. |
2004-01-21 |
2023-08-12 |
human |
| Derek W Gilroy, Paul R Colville-Nash, Shaun McMaster, Deborah A Sawatzky, Derek A Willoughby, Toby Lawrenc. Inducible cyclooxygenase-derived 15-deoxy(Delta)12-14PGJ2 brings about acute inflammatory resolution in rat pleurisy by inducing neutrophil and macrophage apoptosis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 17. issue 15. 2004-01-06. PMID:14563690. |
inducible cyclooxygenase-derived 15-deoxy(delta)12-14pgj2 brings about acute inflammatory resolution in rat pleurisy by inducing neutrophil and macrophage apoptosis. |
2004-01-06 |
2023-08-12 |
rat |
| Mamoru Satou, Syu Aizawa, Makoto Hayakari, Keizou Ookawa, Shigeki Tsuchid. Enhanced sensitivity to cis-diamminedichloroplatinum(II) of a human carcinoma cell line with mutated p53 gene by cyclin-dependent kinase inhibitor p21(WAF1) expression. Cancer science. vol 94. issue 3. 2004-01-05. PMID:12824923. |
by immunoblotting, these proteins were identified as c-jun n-terminal kinase (jnk) 2 and p38 mitogen-activated protein kinase (mapk) delta, respectively, both of which are believed to be involved in apoptosis induction by cddp. |
2004-01-05 |
2023-08-12 |
human |
| M A de Pablo, S A Susin, E Jacotot, N Larochette, P Costantini, L Ravagnan, N Zamzami, G Kroeme. Palmitate induces apoptosis via a direct effect on mitochondria. Apoptosis : an international journal on programmed cell death. vol 4. issue 2. 2003-12-23. PMID:14634285. |
here we show that the palmitate-induced dissipation of the mitochondrial transmembrane potential (delta psi m), which precedes nuclear apoptosis, is not prevented by inhibitors of mrna synthesis, protein synthesis, caspases, or pro-apoptotic ceramide signaling. |
2003-12-23 |
2023-08-12 |
Not clear |