| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Rovere, E Clementi, M Ferrarini, S Heltai, C Sciorati, M G Sabbadini, C Rugarli, A A Manfred. CD95 engagement releases calcium from intracellular stores of long term activated, apoptosis-prone gammadelta T cells. Journal of immunology (Baltimore, Md. : 1950). vol 156. issue 12. 1996-07-25. PMID:8648106. |
as intracellular ca2+ release by inhibition of endoplasmic reticulum atpases induces apoptosis in both recently and long term activated gamma delta cells, the molecular regulation of activation-dependent apoptosis is likely to involve events upstream of cd95-dependent ca2+ release. |
1996-07-25 |
2023-08-12 |
human |
| B Combadière, M Freedman, L Chen, E W Shores, P Love, M J Lenard. Qualitative and quantitative contributions of the T cell receptor zeta chain to mature T cell apoptosis. The Journal of experimental medicine. vol 183. issue 5. 1996-07-18. PMID:8642321. |
we found that the tcr-zeta chain, while not absolutely required, was especially effective at promoting mature t cell apoptosis compared with the cd3 epsilon, gamma, or delta chains. |
1996-07-18 |
2023-08-12 |
Not clear |
| S A Huber, A Mortensen, G Moulto. Modulation of cytokine expression by CD4+ T cells during coxsackievirus B3 infections of BALB/c mice initiated by cells expressing the gamma delta + T-cell receptor. Journal of virology. vol 70. issue 5. 1996-06-21. PMID:8627781. |
no apoptosis was observed in h310a1 virus-infected mice, but apoptosis was induced subsequent to gamma delta +-t-cell transfer. |
1996-06-21 |
2023-08-12 |
mouse |
| M Castedo, A Macho, N Zamzami, T Hirsch, P Marchetti, J Uriel, G Kroeme. Mitochondrial perturbations define lymphocytes undergoing apoptotic depletion in vivo. European journal of immunology. vol 25. issue 12. 1996-03-01. PMID:8566012. |
we have recently shown that lymphocyte apoptosis induced by dexamethasone or superantigens is accompanied by reduction of mitochondrial transmembrane potential (delta psi m) which precedes nuclear dna fragmentation. |
1996-03-01 |
2023-08-12 |
mouse |
| M Castedo, A Macho, N Zamzami, T Hirsch, P Marchetti, J Uriel, G Kroeme. Mitochondrial perturbations define lymphocytes undergoing apoptotic depletion in vivo. European journal of immunology. vol 25. issue 12. 1996-03-01. PMID:8566012. |
here, we demonstrate that fluorochromes such as 3,3' dihexyloxacarbocyanine iodide [dioc6(3)] which measure delta psi m, or fluorochromes such as hydroethidine (he) which measure mitochondrial superoxide anion production allow the identification of thymocytes or peripheral t lymphocytes which are eliminated by apoptosis in vivo. |
1996-03-01 |
2023-08-12 |
mouse |
| M Castedo, A Macho, N Zamzami, T Hirsch, P Marchetti, J Uriel, G Kroeme. Mitochondrial perturbations define lymphocytes undergoing apoptotic depletion in vivo. European journal of immunology. vol 25. issue 12. 1996-03-01. PMID:8566012. |
delta psi m reduction and/or enhanced he oxidation are also found when apoptosis is induced by a series of pathogenic agents. |
1996-03-01 |
2023-08-12 |
mouse |
| C Richter, M Schweizer, A Cossarizza, C Francesch. Control of apoptosis by the cellular ATP level. FEBS letters. vol 378. issue 2. 1996-02-22. PMID:8549813. |
the mitochondrial membrane potential (delta psi), which is the driving force for mitochondrial atp synthesis, declines during apoptosis, and maintenance of delta psi prevents apoptosis. |
1996-02-22 |
2023-08-12 |
Not clear |
| F Spinozzi, I Nicoletti, E Agea, S Belia, R Moraca, G Migliorati, C Riccardi, F Grignani, A Bertott. IL-4 is able to reverse the CD2-mediated negative apoptotic signal to CD4-CD8- alpha beta and/or gamma delta T lymphocytes. Immunology. vol 86. issue 3. 1996-02-20. PMID:8550074. |
induction of apoptosis was prevented by the presence of interleukin-4 (il-4) as well as by endonuclease inactivation with 100 microm zncl2, but enhanced by the contemporary block of protein kinase c. thus it seems that in resting t lymphocytes the strong calcium signal delivered by the alternative cd2 activation pathway may act as a negative apoptotic signal in both alpha beta and gamma delta t cells with low (non-major histocompatibility complex restricted) antigenic affinity, so limiting the extension of polyclonal t-cell growth. |
1996-02-20 |
2023-08-12 |
Not clear |
| M A Brooks, A N Ali, P C Turner, R W Moye. A rabbitpox virus serpin gene controls host range by inhibiting apoptosis in restrictive cells. Journal of virology. vol 69. issue 12. 1996-01-11. PMID:7494278. |
morphological examination of rpv delta spi-1-infected a549 cells, together with an observed fragmentation of cellular dna, suggests that the host range defect is associated with the onset of apoptosis. |
1996-01-11 |
2023-08-12 |
human |
| M A Brooks, A N Ali, P C Turner, R W Moye. A rabbitpox virus serpin gene controls host range by inhibiting apoptosis in restrictive cells. Journal of virology. vol 69. issue 12. 1996-01-11. PMID:7494278. |
apoptosis is seen only in rpv delta spi-1 infection of nonpermissive (a549 or pk-15) cells and is absent in all wild-type rpv infections and rpv delta spi-2 mutant infections examined to date. |
1996-01-11 |
2023-08-12 |
human |
| M A Brooks, A N Ali, P C Turner, R W Moye. A rabbitpox virus serpin gene controls host range by inhibiting apoptosis in restrictive cells. Journal of virology. vol 69. issue 12. 1996-01-11. PMID:7494278. |
although the spi-1 gene is expressed early, before dna replication, the triggering apoptotic event occurs late in the infection, as rpv delta spi-1-infected a549 cells do not undergo apoptosis when infections are carried out in the presence of cytosine arabinoside. |
1996-01-11 |
2023-08-12 |
human |
| C Brancolini, M Benedetti, C Schneide. Microfilament reorganization during apoptosis: the role of Gas2, a possible substrate for ICE-like proteases. The EMBO journal. vol 14. issue 21. 1996-01-02. PMID:7489707. |
we demonstrate that during apoptosis the c-terminal domain of gas2 is removed by proteolytic cleavage, resulting in a protein that is similar in size to the described delta 276-314. |
1996-01-02 |
2023-08-12 |
Not clear |
| A T Baldé, J L Sarthou, C Roussilho. Acute Plasmodium falciparum infection is associated with increased percentages of apoptotic cells. Immunology letters. vol 46. issue 1-2. 1995-12-07. PMID:7590929. |
selective immunomagnetic cell isolations carried out immediately before apoptosis quantitation showed that this process affected not only the alpha beta t cells (cd4+ t cells as well as cd8+ t cells) but also the gamma delta t cells and the b-lymphocyte subset. |
1995-12-07 |
2023-08-12 |
human |
| D Cortez, L Kadlec, A M Pendergas. Structural and signaling requirements for BCR-ABL-mediated transformation and inhibition of apoptosis. Molecular and cellular biology. vol 15. issue 10. 1995-10-25. PMID:7565705. |
a bcr-abl deletion mutant (delta 176-427) that activates ras and blocks apoptosis but has severely impaired transforming ability in 32d cells has been identified. |
1995-10-25 |
2023-08-12 |
human |
| A Macho, M Castedo, P Marchetti, J J Aguilar, D Decaudin, N Zamzami, P M Girard, J Uriel, G Kroeme. Mitochondrial dysfunctions in circulating T lymphocytes from human immunodeficiency virus-1 carriers. Blood. vol 86. issue 7. 1995-10-19. PMID:7670095. |
in several models of lymphocyte apoptosis, two alterations of mitochondrial function precede advanced dna fragmentation: (1) a reduction of mitochondrial transmembrane potential (delta psi m) and (2) an increase in mitochondrial generation of superoxide anion. |
1995-10-19 |
2023-08-12 |
human |
| Y Wu, G Pani, K Siminovitch, N Hozum. Antigen receptor-triggered apoptosis in immature B cell lines is associated with the binding of a 44-kDa phosphoprotein to the PTP1C tyrosine phosphatase. European journal of immunology. vol 25. issue 8. 1995-10-10. PMID:7664792. |
while cross-linking of the membrane igm (migm) molecules expressed on wehi 231 lymphoma cells induces these cells to undergo apoptosis, we have previously observed that ligation of the migd expressed on igd-transfected wehi 231 (w delta) cells is not associated with induction of cell death. |
1995-10-10 |
2023-08-12 |
Not clear |
| J H Lee, H S Kim, S Y Jeong, I K Ki. Induction of p53 and apoptosis by delta 12-PGJ2 in human hepatocarcinoma SK-HEP-1 cells. FEBS letters. vol 368. issue 2. 1995-09-07. PMID:7628635. |
induction of p53 and apoptosis by delta 12-pgj2 in human hepatocarcinoma sk-hep-1 cells. |
1995-09-07 |
2023-08-12 |
human |
| J H Lee, H S Kim, S Y Jeong, I K Ki. Induction of p53 and apoptosis by delta 12-PGJ2 in human hepatocarcinoma SK-HEP-1 cells. FEBS letters. vol 368. issue 2. 1995-09-07. PMID:7628635. |
human hepatocarcinoma cells (sk-hep-1) were induced to die through apoptosis by treatment with delta 12-prostaglandin (pg)j2, as characterized by the appearance of a typical dna ladder. |
1995-09-07 |
2023-08-12 |
human |
| J H Lee, H S Kim, S Y Jeong, I K Ki. Induction of p53 and apoptosis by delta 12-PGJ2 in human hepatocarcinoma SK-HEP-1 cells. FEBS letters. vol 368. issue 2. 1995-09-07. PMID:7628635. |
the induction of apoptosis by delta 12-pgj2 was specifically blocked by cycloheximide (chx). |
1995-09-07 |
2023-08-12 |
human |
| J H Lee, H S Kim, S Y Jeong, I K Ki. Induction of p53 and apoptosis by delta 12-PGJ2 in human hepatocarcinoma SK-HEP-1 cells. FEBS letters. vol 368. issue 2. 1995-09-07. PMID:7628635. |
however, the finding that delta 12-pgj2 is also active against hep 3b cells which are devoid of a functional p53 indicates that p53 may not be the critical requirement for inducing apoptosis by delta 12-pgj2. |
1995-09-07 |
2023-08-12 |
human |