| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K L Schavolt, J A Pietenpo. p53 and Delta Np63 alpha differentially bind and regulate target genes involved in cell cycle arrest, DNA repair and apoptosis. Oncogene. vol 26. issue 42. 2007-10-24. PMID:17404570. |
p53 and delta np63 alpha differentially bind and regulate target genes involved in cell cycle arrest, dna repair and apoptosis. |
2007-10-24 |
2023-08-12 |
human |
| Xian-Qi Feng, Yong You, Juan Xiao, Ping Zo. [Thapsigargin-induced apoptosis of K562 cells and its mechanism]. Zhongguo shi yan xue ye xue za zhi. vol 14. issue 1. 2007-10-19. PMID:16584585. |
after the treatment of leukemia cell line k562 by thapsigargin, morphological change of apoptotic cells was investigated by ao/eb fluorescent staining under fluorescent microscope; apoptosis rate was determined with annexin v-fitc/pi double staining by flow cytometry; intracellular calcium concentrations ([ca(2+)]i) were measured by fluorescence spectrophotometer with calcium sensitive fluorescence indicator fura-2/am; mitochondrial transmembrance potentials (delta psi m) was detected on flow cytometry through staining of rhodamine (rh123); the changes of caspase-3, -7, -9, -12, cytochrome c, grp78 proteins were detected by western blot. |
2007-10-19 |
2023-08-12 |
Not clear |
| Xian-Qi Feng, Yong You, Juan Xiao, Ping Zo. [Thapsigargin-induced apoptosis of K562 cells and its mechanism]. Zhongguo shi yan xue ye xue za zhi. vol 14. issue 1. 2007-10-19. PMID:16584585. |
thapsigargin-induced apoptosis in k562 cells is associated closely with the disruption of the delta psi m and the release of cytochrome c from mitochondria, mitochondria participates in endoplasmic reticulum stress-induced apoptosis in k562 cells. |
2007-10-19 |
2023-08-12 |
Not clear |
| Sebastien Bonnet, Gael Rochefort, Gopinath Sutendra, Stephen L Archer, Alois Haromy, Linda Webster, Kyoko Hashimoto, Sandra N Bonnet, Evangelos D Michelaki. The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 27. 2007-09-26. PMID:17596340. |
inhibition of nfatc2 by vivit or cyclosporine restored kv1.5 expression and current, decreased [ca(2+)](i), [k(+)](i), bcl-2, and delta psi m, leading to decreased proliferation and increased apoptosis in vitro. |
2007-09-26 |
2023-08-12 |
human |
| Joanne Durgan, Nicholas Michael, Nick Totty, Peter J Parke. Novel phosphorylation site markers of protein kinase C delta activation. FEBS letters. vol 581. issue 18. 2007-09-19. PMID:17603046. |
protein kinase c delta (pkcdelta) is a ser/thr kinase which regulates numerous cellular processes, including proliferation, differentiation, migration and apoptosis. |
2007-09-19 |
2023-08-12 |
Not clear |
| Tracie A DeVries-Seimon, Angela M Ohm, Michael J Humphries, Mary E Reylan. Induction of apoptosis is driven by nuclear retention of protein kinase C delta. The Journal of biological chemistry. vol 282. issue 31. 2007-09-13. PMID:17562707. |
induction of apoptosis is driven by nuclear retention of protein kinase c delta. |
2007-09-13 |
2023-08-12 |
Not clear |
| Tracie A DeVries-Seimon, Angela M Ohm, Michael J Humphries, Mary E Reylan. Induction of apoptosis is driven by nuclear retention of protein kinase C delta. The Journal of biological chemistry. vol 282. issue 31. 2007-09-13. PMID:17562707. |
protein kinase c delta (pkc delta) mediates apoptosis downstream of many apoptotic stimuli. |
2007-09-13 |
2023-08-12 |
Not clear |
| Tracie A DeVries-Seimon, Angela M Ohm, Michael J Humphries, Mary E Reylan. Induction of apoptosis is driven by nuclear retention of protein kinase C delta. The Journal of biological chemistry. vol 282. issue 31. 2007-09-13. PMID:17562707. |
full-length pkc delta is found in all cells, whereas the catalytic fragment of pkc delta, generated by caspase cleavage, is only present in cells undergoing apoptosis. |
2007-09-13 |
2023-08-12 |
Not clear |
| Tracie A DeVries-Seimon, Angela M Ohm, Michael J Humphries, Mary E Reylan. Induction of apoptosis is driven by nuclear retention of protein kinase C delta. The Journal of biological chemistry. vol 282. issue 31. 2007-09-13. PMID:17562707. |
however, caspase cleavage of pkc delta per se is not required for apoptosis, as an uncleavable form of pkc delta induces apoptosis when retained in the nucleus by the addition of an sv-40 nuclear localization signal. |
2007-09-13 |
2023-08-12 |
Not clear |
| Tracie A DeVries-Seimon, Angela M Ohm, Michael J Humphries, Mary E Reylan. Induction of apoptosis is driven by nuclear retention of protein kinase C delta. The Journal of biological chemistry. vol 282. issue 31. 2007-09-13. PMID:17562707. |
finally, we show that kinase negative full-length pkc delta does not translocate to the nucleus in apoptotic cells but instead inhibits apoptosis by blocking nuclear import of endogenous pkc delta. |
2007-09-13 |
2023-08-12 |
Not clear |
| Tracie A DeVries-Seimon, Angela M Ohm, Michael J Humphries, Mary E Reylan. Induction of apoptosis is driven by nuclear retention of protein kinase C delta. The Journal of biological chemistry. vol 282. issue 31. 2007-09-13. PMID:17562707. |
these studies demonstrate that generation of the pkc delta catalytic fragment is a critical step for commitment to apoptosis and that nuclear import and export of pkc delta plays a key role in regulating the survival/death pathway. |
2007-09-13 |
2023-08-12 |
Not clear |
| Valeria C Grossoni, Karina B Falbo, Marcelo G Kazanietz, Elisa D Bal de Kier Joffé, Alejandro J Urtrege. Protein kinase C delta enhances proliferation and survival of murine mammary cells. Molecular carcinogenesis. vol 46. issue 5. 2007-09-12. PMID:17219421. |
protein kinase c (pkc) delta, a member of the novel family of pkc serine-threonine kinases, has been implicated in negative regulation of proliferation and apoptosis in a large number of cell types, including breast cancer cell lines, and postulated as a tumor suppressor gene. |
2007-09-12 |
2023-08-12 |
Not clear |
| Fang Gong, Yanhui Ma, Anlun Ma, Qiwen Yu, Jiying Zhang, Hong Nie, Xuehua Chen, Baihua Shen, Ningli Li, Dongqing Zhan. A lectin from Chinese mistletoe increases gammadelta T cell-mediated cytotoxicity through induction of caspase-dependent apoptosis. Acta biochimica et biophysica Sinica. vol 39. issue 6. 2007-08-31. PMID:17558450. |
the cytotoxic properties of delta t cells was evaluated by using a (51)cr release test and employed fluorescence-activated cell sorting and enzyme-linked immunosorbent assay analysis to quantify translocation of the cell membrane phospholipid, phosphatidylserine and nuclear dna fragmentation during apoptosis. |
2007-08-31 |
2023-08-12 |
human |
| Manus W Ward, Heinrich J Huber, Petronela Weisová, Heiko Düssmann, David G Nicholls, Jochen H M Preh. Mitochondrial and plasma membrane potential of cultured cerebellar neurons during glutamate-induced necrosis, apoptosis, and tolerance. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 31. 2007-08-28. PMID:17670970. |
statistical analysis of the changes in delta psi(m) or delta psi(p) at a single-cell level revealed two major correlations; those neurons displaying a more pronounced depolarization of delta psi(p) during the initial phase of glutamate excitation entered apoptosis more rapidly, and neurons that displayed a more pronounced hyperpolarization of delta psi(m) after glutamate excitation survived longer. |
2007-08-28 |
2023-08-12 |
Not clear |
| Shanggen Zhou, James W Dewill. Proteasome-mediated CCAAT/enhancer-binding protein delta (C/EBPdelta) degradation is ubiquitin-independent. The Biochemical journal. vol 405. issue 2. 2007-07-10. PMID:17373909. |
c/ebpdelta (ccaat/enhancer-binding protein delta) is a member of the c/ebp family of nuclear proteins that function in the control of cell growth, survival, differentiation and apoptosis. |
2007-07-10 |
2023-08-12 |
Not clear |
| Yi-Hsuan Chen, Hui-Yin Chen, Chin-Lin Hsu, Gow-Chin Ye. Induction of apoptosis by the Lactuca indica L. in human leukemia cell line and its active components. Journal of agricultural and food chemistry. vol 55. issue 5. 2007-06-20. PMID:17295517. |
our results also indicate that eel-induced apoptosis in hl-60 cells is associated with the loss of mitochondrial membrane potential (delta psi m). |
2007-06-20 |
2023-08-12 |
human |
| Chenhong Luo, Akihiro Nawa, Youhei Yamauchi, Shinichi Kohno, Youko Ushijima, Fumi Goshima, Fumitaka Kikkawa, Yukihiro Nishiyam. Intercellular trafficking and cytotoxicity of recombinant HSV-1 thymidine kinase fused with HSV-2 US11 RXP repeat peptide. Virus genes. vol 34. issue 3. 2007-06-14. PMID:16927131. |
we also found that transfection of tkc delta 6-rxp (lacking the c-terminal six amino residues of tk), tk-rxp, and tkn delta 66-rxp (lacking the n-terminal 66 amino residues of tk) induced apoptosis even in the absence of gcv. |
2007-06-14 |
2023-08-12 |
Not clear |
| M Guo, L-P Song, Y Jiang, W Liu, Y Yu, G-Q Che. Hypoxia-mimetic agents desferrioxamine and cobalt chloride induce leukemic cell apoptosis through different hypoxia-inducible factor-1alpha independent mechanisms. Apoptosis : an international journal on programmed cell death. vol 11. issue 1. 2007-05-31. PMID:16374551. |
metavanadate and sodium nitroprusside significantly abrogate dfo rather than cocl(2)-induced mitochondrial delta psi m collapse, caspase-3/8 activation, mcl-1 cleavage and apoptosis, but they fail to influence dfo and cocl(2)-induced hif-1alpha protein accumulation. |
2007-05-31 |
2023-08-12 |
Not clear |
| M L Morrison, K Williamson, K Arthur, G J Price, P W Hamilton, P Maxwel. Phenotypic changes in mitochondrial membrane potential (Delta psi(m)) during valinomycin-induced depolarisation and apoptosis. Cellular oncology : the official journal of the International Society for Cellular Oncology. vol 27. issue 4. 2007-04-13. PMID:16308472. |
phenotypic changes in mitochondrial membrane potential (delta psi(m)) during valinomycin-induced depolarisation and apoptosis. |
2007-04-13 |
2023-08-12 |
Not clear |
| M L Morrison, K Williamson, K Arthur, G J Price, P W Hamilton, P Maxwel. Phenotypic changes in mitochondrial membrane potential (Delta psi(m)) during valinomycin-induced depolarisation and apoptosis. Cellular oncology : the official journal of the International Society for Cellular Oncology. vol 27. issue 4. 2007-04-13. PMID:16308472. |
this demonstrated that the haram texture features (mean of the haralick texture features) were highly valuable in describing the transition of delta psi(m) as the cell undergoes apoptosis. |
2007-04-13 |
2023-08-12 |
Not clear |