| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Maria J Comin, Gabriella Czifra, Noemi Kedei, Andrea Telek, Nancy E Lewin, Sofiya Kolusheva, Julia F Velasquez, Ryan Kobylarz, Raz Jelinek, Peter M Blumberg, Victor E Marque. Conformationally constrained analogues of diacylglycerol (DAG). 31. Modulation of the biological properties of diacylgycerol lactones (DAG-lactones) containing rigid-rod acyl groups separated from the core lactone by spacer units of different lengths. Journal of medicinal chemistry. vol 52. issue 10. 2009-07-17. PMID:19379015. |
the kinetics and site of translocation for the pkc isozymes alpha and delta upon treatment with the compounds were also studied as well as the early response of erk phosphorylation and the late response of induction of apoptosis in the human prostatic carcinoma cell line lncap. |
2009-07-17 |
2023-08-12 |
human |
| Kenneth K Wu, Jun-Yang Lio. Cyclooxygenase inhibitors induce colon cancer cell apoptosis Via PPARdelta --> 14-3-3epsilon pathway. Methods in molecular biology (Clifton, N.J.). vol 512. 2009-07-16. PMID:19347284. |
there is evidence that they induce colon cancer cell apoptosis by suppressing peroxisome proliferator-activated receptor delta (ppardelta) through inhibition of cox-2-derived prostacyclin (pgi2). |
2009-07-16 |
2023-08-12 |
Not clear |
| Ping-Yuan Lin, Jeng-Woei Lee, Ming-Huei Liao, Hsue-Yin Hsu, Shu-Jun Chiu, Hung-Jen Liu, Wen-Ling Shi. Modulation of p53 by mitogen-activated protein kinase pathways and protein kinase C delta during avian reovirus S1133-induced apoptosis. Virology. vol 385. issue 2. 2009-06-24. PMID:19168198. |
modulation of p53 by mitogen-activated protein kinase pathways and protein kinase c delta during avian reovirus s1133-induced apoptosis. |
2009-06-24 |
2023-08-12 |
Not clear |
| Ping-Yuan Lin, Jeng-Woei Lee, Ming-Huei Liao, Hsue-Yin Hsu, Shu-Jun Chiu, Hung-Jen Liu, Wen-Ling Shi. Modulation of p53 by mitogen-activated protein kinase pathways and protein kinase C delta during avian reovirus S1133-induced apoptosis. Virology. vol 385. issue 2. 2009-06-24. PMID:19168198. |
arv s1133 activates pkc delta and p38 and jnk/sapk pathways, and inhibition of ras, p38, jnk/sapk and pkc delta works efficiently against apoptosis. |
2009-06-24 |
2023-08-12 |
Not clear |
| Shuhua Xia, Zhihong Chen, Lora W Forman, Douglas V Falle. PKCdelta survival signaling in cells containing an activated p21Ras protein requires PDK1. Cellular signalling. vol 21. issue 4. 2009-06-22. PMID:19146951. |
protein kinase c delta (pkcdelta) modulates cell survival and apoptosis in diverse cellular systems. |
2009-06-22 |
2023-08-12 |
Not clear |
| Tong Wang, Yao-ying Zeng, Fei-yue Xing, Fang He, Jiong-kun Wan. [The changes of the thymocyte mitochondria mediated by nitric oxide in thymocyte apoptosis]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 22. issue 3. 2009-06-08. PMID:16643785. |
to study the changes of mitochondrial potential (delta psi m) and cardiolipin (cl) content during thymocyte apoptosis mediated by nitric oxide (no). |
2009-06-08 |
2023-08-12 |
Not clear |
| Chien-Lin Chen, Hong-Chen Che. Functional suppression of E-cadherin by protein kinase Cdelta. Journal of cell science. vol 122. issue Pt 4. 2009-04-21. PMID:19174468. |
protein kinase c (pkc) delta, a member of the novel pkc subfamily, has been shown to have an important role in cell proliferation, differentiation, apoptosis and cell motility. |
2009-04-21 |
2023-08-12 |
Not clear |
| Lin Wang, Jin Cao, Dawei Chen, Xuezhong Liu, Hao Lu, Zongping Li. Role of oxidative stress, apoptosis, and intracellular homeostasis in primary cultures of rat proximal tubular cells exposed to cadmium. Biological trace element research. vol 127. issue 1. 2009-04-20. PMID:18802671. |
simultaneously, elevation of intracellular [ca(2+)]i and reactive oxygen species (ros) levels, significant depletion of mitochondrial membrane potential(delta psi) and cellular glutathione (gsh), intracellular acidification, and inhibition of na(+), k(+)-atpase and ca(2+)-atpase activities were revealed in a dose-dependent manner during the exposure, while the cellular death and the apoptosis could be markedly reversed by n-acetyl-l-cysteine (nac). |
2009-04-20 |
2023-08-12 |
rat |
| Te-Chun Hsia, Jai-Sing Yang, Guang-Wei Chen, Tsan-Hung Chiu, Hsu-Feng Lu, Mei-Due Yang, Fu-Shun Yu, Kuo-Ching Liu, Kuang-Chi Lai, Chin-Chung Lin, Jing-Gung Chun. The roles of endoplasmic reticulum stress and Ca2+ on rhein-induced apoptosis in A-549 human lung cancer cells. Anticancer research. vol 29. issue 1. 2009-04-16. PMID:19331167. |
flow cytometric analysis demonstrated that rhein increased the levels of gadd153 and grp78, both hallmarks of endoplasmic reticulum stress, promoted ros and ca2+ production, induced the loss of mitochondrial membrane potential (delta psi(m)), promoted cytochrome c release from mitochondria, promoted capase-3 activation and led to apoptosis. |
2009-04-16 |
2023-08-12 |
human |
| Chu Chang Chua, Jinping Gao, Ye-Shih Ho, Xingshun Xu, I-Chun Kuo, Kaw-Yan Chua, Hong Wang, Ronald C Hamdy, John C Reed, Balvin H L Chu. Over-expression of a modified bifunctional apoptosis regulator protects against cardiac injury and doxorubicin-induced cardiotoxicity in transgenic mice. Cardiovascular research. vol 81. issue 1. 2009-04-10. PMID:18805781. |
we hypothesize that over-expression of bar delta ring prevents apoptosis and injury following ischaemia/reperfusion (i/r) and attenuates doxorubicin (dox)-induced cardiotoxicity. |
2009-04-10 |
2023-08-12 |
mouse |
| Jo-Lin Chen, H Helen Lin, Kwang-Jin Kim, Anning Lin, J-H James Ou, David K An. PKC delta signaling: a dual role in regulating hypoxic stress-induced autophagy and apoptosis. Autophagy. vol 5. issue 2. 2009-03-30. PMID:19098423. |
pkc delta signaling: a dual role in regulating hypoxic stress-induced autophagy and apoptosis. |
2009-03-30 |
2023-08-12 |
Not clear |
| Young-Sook Lee, Kyung-Cheol Sohn, Ki-Hwan Kim, Moon-June Cho, Gang Min Hur, Tae-Jin Yoon, Sung Kyu Kim, Kyungmoon Lee, Jeung-Hoon Lee, Chang Deok Ki. Role of protein kinase C delta in X-ray-induced apoptosis of keratinocyte. Experimental dermatology. vol 18. issue 1. 2009-03-26. PMID:18637130. |
role of protein kinase c delta in x-ray-induced apoptosis of keratinocyte. |
2009-03-26 |
2023-08-12 |
Not clear |
| Young-Sook Lee, Kyung-Cheol Sohn, Ki-Hwan Kim, Moon-June Cho, Gang Min Hur, Tae-Jin Yoon, Sung Kyu Kim, Kyungmoon Lee, Jeung-Hoon Lee, Chang Deok Ki. Role of protein kinase C delta in X-ray-induced apoptosis of keratinocyte. Experimental dermatology. vol 18. issue 1. 2009-03-26. PMID:18637130. |
in this study, we investigated the process of x-ray-induced apoptosis of skin keratinocyte, and the functional role of protein kinase c delta (pkcdelta) and downstream signalling cascade. |
2009-03-26 |
2023-08-12 |
Not clear |
| Begońa G Miguel, Inmaculada Fernández, Inmaculada Toboso, Alba Agudo-López, Edgardo Catalán, Ana M Martíne. Sphingosylphosphorylcholine induces mitochondria-mediated apoptosis in neuro 2a cells: involvement of protein kinase C. Acta neurobiologiae experimentalis. vol 68. issue 4. 2009-03-13. PMID:19112467. |
treating cells with sphingosylphosphorylcholine resulted in activation of protein kinase c delta, which is necessary, together with elevation of ca2+ for sphingosylphosphorylcholine-induced apoptosis. |
2009-03-13 |
2023-08-12 |
Not clear |
| Begońa G Miguel, Inmaculada Fernández, Inmaculada Toboso, Alba Agudo-López, Edgardo Catalán, Ana M Martíne. Sphingosylphosphorylcholine induces mitochondria-mediated apoptosis in neuro 2a cells: involvement of protein kinase C. Acta neurobiologiae experimentalis. vol 68. issue 4. 2009-03-13. PMID:19112467. |
a rapid translocation from cytosol to membrane, and a proteolytic protein kinase c delta cleavage was found, probably due to activation of caspase-3, to give a catalytically active fragment involved in cellular apoptosis. |
2009-03-13 |
2023-08-12 |
Not clear |
| Xiaoyong Lei, Sheng Zhang, Alan Bohrer, Sasanka Ramanadha. Calcium-independent phospholipase A2 (iPLA2 beta)-mediated ceramide generation plays a key role in the cross-talk between the endoplasmic reticulum (ER) and mitochondria during ER stress-induced insulin-secreting cell apoptosis. The Journal of biological chemistry. vol 283. issue 50. 2009-02-19. PMID:18936091. |
exposure to ceramide alone induces loss in delta psi and apoptosis and these are suppressed by forskolin. |
2009-02-19 |
2023-08-12 |
Not clear |
| Jürgen Löhler, Heidrun Hirner, Bernhard Schmidt, Klaus Kramer, Dietmar Fischer, Dietmar R Thal, Frank Leithäuser, Uwe Knippschil. Immunohistochemical characterisation of cell-type specific expression of CK1delta in various tissues of young adult BALB/c mice. PloS one. vol 4. issue 1. 2009-02-17. PMID:19137063. |
casein kinase 1 delta (ck1delta) phosphorylates many key proteins playing important roles in such biological processes as cell growth, differentiation, apoptosis, circadian rhythm and vesicle transport. |
2009-02-17 |
2023-08-12 |
mouse |
| Kanwal Ahmed, Yuji Matsuya, Hideo Nemoto, Syed Faisal Haider Zaidi, Toshiro Sugiyama, Yoko Yoshihisa, Tadamichi Shimizu, Takashi Kond. Mechanism of apoptosis induced by a newly synthesized derivative of macrosphelides with a thiazole side chain. Chemico-biological interactions. vol 177. issue 3. 2009-02-10. PMID:19014919. |
moreover, antioxidant enzymes catalase and/or superoxide dismutase conjugated with polyethylene glycol also inhibit mst-2-induced ros formation, apoptosis and delta psi(m) loss suggesting thereby pro-oxidant effects of mst-2. |
2009-02-10 |
2023-08-12 |
human |
| M Lasfer, N Vadrot, L Aoudjehane, F Conti, A F Bringuier, G Feldmann, F Reyl-Desmar. Cadmium induces mitochondria-dependent apoptosis of normal human hepatocytes. Cell biology and toxicology. vol 24. issue 1. 2009-02-03. PMID:17610031. |
in order to investigate the involvement of mitochondria in cadmium-induced apoptosis, we measured the mitochondrial membrane potential (delta(psim)). |
2009-02-03 |
2023-08-12 |
human |
| Marina Ferrarini, Fanny Delfanti, Monica Gianolini, Chiara Rizzi, Massimo Alfano, Adriano Lazzarin, Priscilla Biswa. NF-kappa B modulates sensitivity to apoptosis, proinflammatory and migratory potential in short- versus long-term cultured human gamma delta lymphocytes. Journal of immunology (Baltimore, Md. : 1950). vol 181. issue 9. 2009-01-21. PMID:18941174. |
nf-kappa b modulates sensitivity to apoptosis, proinflammatory and migratory potential in short- versus long-term cultured human gamma delta lymphocytes. |
2009-01-21 |
2023-08-12 |
human |