| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Manuchair Ebadi, Sushil Sharm. Metallothioneins 1 and 2 attenuate peroxynitrite-induced oxidative stress in Parkinson disease. Experimental biology and medicine (Maywood, N.J.). vol 231. issue 9. 2006-10-25. PMID:17018883. |
sin-1-induced lipid peroxidation, reactive oxygen species synthesis, caspase-3 activation, and apoptosis were attenuated by metallothionein gene overexpression and augmented by metallothionein gene down-regulation. |
2006-10-25 |
2023-08-12 |
mouse |
| Ting Wu, Xin-Sheng Ding, Wei Wang, Jin W. MCI-186 (3-methyl-1-phenyl-2-pyrazolin-5-one) attenuated simulated ischemia/reperfusion injury in cultured rat hippocampal cells. Biological & pharmaceutical bulletin. vol 29. issue 8. 2006-10-18. PMID:16880614. |
mci-186 effectively protects neuron injury after simulated ischemia/reperfusion by inhibiting lipid peroxidation, reducing ca2+ overload, elevating mitochondria membrane potential, and decreasing apoptosis. |
2006-10-18 |
2023-08-12 |
rat |
| C Bouaziz, S Abid-Essefi, A Bouslimi, E El Golli, H Bach. Cytotoxicity and related effects of T-2 toxin on cultured Vero cells. Toxicon : official journal of the International Society on Toxinology. vol 48. issue 3. 2006-10-18. PMID:16884754. |
in this study, cytotoxicity and apotosis induction by t-2 toxin was investigated in vitro on vero cell line using the mtt and the neutral red viability assays, the induction of lipid peroxidation, the decrease of macromolecule levels (protein, dna and rna), dna fragmentation and caspase-3-dependent apoptosis induction. |
2006-10-18 |
2023-08-12 |
human |
| K Bhatia, M Kaur, F Atif, M Ali, H Rehman, S Rahman, S Raisuddi. Aqueous extract of Trigonella foenum-graecum L. ameliorates additive urotoxicity of buthionine sulfoximine and cyclophosphamide in mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 44. issue 10. 2006-10-05. PMID:16828947. |
restoration of gsh by extract treatment may play an important role in reversing cp-induced apoptosis and free radical-mediated lpo in urinary bladder. |
2006-10-05 |
2023-08-12 |
mouse |
| Abha Sharma, Brad Patrick, Jie Li, Rajendra Sharma, Prince V S Jeyabal, Prasada M R V Reddy, Sanjay Awasthi, Yogesh C Awasth. Glutathione S-transferases as antioxidant enzymes: small cell lung cancer (H69) cells transfected with hGSTA1 resist doxorubicin-induced apoptosis. Archives of biochemistry and biophysics. vol 452. issue 2. 2006-09-26. PMID:16890185. |
in order to examine the protective role of alpha-class gst isozyme hgsta1-1 against doxorubicin (dox)-induced lipid peroxidation, cytotoxicity, and apoptosis, human small cell lung cancer (sclc) h69 cells were stably transfected with hgsta1. |
2006-09-26 |
2023-08-12 |
human |
| Abha Sharma, Brad Patrick, Jie Li, Rajendra Sharma, Prince V S Jeyabal, Prasada M R V Reddy, Sanjay Awasthi, Yogesh C Awasth. Glutathione S-transferases as antioxidant enzymes: small cell lung cancer (H69) cells transfected with hGSTA1 resist doxorubicin-induced apoptosis. Archives of biochemistry and biophysics. vol 452. issue 2. 2006-09-26. PMID:16890185. |
these results are consistent with the idea that the alpha-class gsts provide protection against oxidative stress by attenuating lipid peroxidation and these enzymes can modulate signaling for apoptosis. |
2006-09-26 |
2023-08-12 |
human |
| b' E Grosicka, B Sadurska, M Szumi\\xc5\\x82o, T Grzela, P \\xc5\\x81azarczyk, J Niderla-Bieli\\xc5\\x84ska, I Rahden-Staro\\xc5\\x8. Effect of glutathione depletion on apoptosis induced by thiram in Chinese hamster fibroblasts. International immunopharmacology. vol 5. issue 13-14. 2006-09-22. PMID:16275629.' |
the concentrations of thiram required to induce cellular gsh depletion (by 40-50%), protein, and membrane lipid peroxidation (2-fold, and 1.7-fold, respectively), as well as to induce apoptosis in v79 chinese hamster fibroblasts without causing necrosis through cytotoxic effects were between 50-100 microm. |
2006-09-22 |
2023-08-12 |
Not clear |
| Hafiz Mohmmad Abdul, Vittorio Calabrese, Menotti Calvani, D Allan Butterfiel. Acetyl-L-carnitine-induced up-regulation of heat shock proteins protects cortical neurons against amyloid-beta peptide 1-42-mediated oxidative stress and neurotoxicity: implications for Alzheimer's disease. Journal of neuroscience research. vol 84. issue 2. 2006-09-19. PMID:16634066. |
pretreatment of primary cortical neuronal cultures with alcar significantly attenuated abeta(1-42)-induced cytotoxicity, protein oxidation, lipid peroxidation, and apoptosis in a dose-dependent manner. |
2006-09-19 |
2023-08-12 |
rat |
| Chuang C Chiueh, Tsugunobu Andoh, P Boon Choc. Induction of thioredoxin and mitochondrial survival proteins mediates preconditioning-induced cardioprotection and neuroprotection. Annals of the New York Academy of Sciences. vol 1042. 2006-09-11. PMID:15965087. |
cytosolic trx1 and mitochondrial trx2 suppress free radical formation, lipid peroxidation, oxidative stress, and mitochondria-dependent apoptosis; knock out/down of either trx1 or trx2 is detrimental to cell survival. |
2006-09-11 |
2023-08-12 |
mouse |
| V V Novitskii, A K Strelis, S B Tkachenko, I E Esimova, T A Shil'ko, O I Urazova, O V Voronkova, V A Sinitsina, O V Filinyuk, N A Zemlyanay. LPO and apoptosis during pulmonary tuberculosis. Bulletin of experimental biology and medicine. vol 140. issue 5. 2006-09-11. PMID:16758605. |
lpo and apoptosis during pulmonary tuberculosis. |
2006-09-11 |
2023-08-12 |
Not clear |
| V V Novitskii, A K Strelis, S B Tkachenko, I E Esimova, T A Shil'ko, O I Urazova, O V Voronkova, V A Sinitsina, O V Filinyuk, N A Zemlyanay. LPO and apoptosis during pulmonary tuberculosis. Bulletin of experimental biology and medicine. vol 140. issue 5. 2006-09-11. PMID:16758605. |
lpo and apoptosis in blood mononuclear cells were studied in patients with pulmonary tuberculosis before and during treatment with standard chemotherapeutics. |
2006-09-11 |
2023-08-12 |
Not clear |
| V V Novitskii, A K Strelis, S B Tkachenko, I E Esimova, T A Shil'ko, O I Urazova, O V Voronkova, V A Sinitsina, O V Filinyuk, N A Zemlyanay. LPO and apoptosis during pulmonary tuberculosis. Bulletin of experimental biology and medicine. vol 140. issue 5. 2006-09-11. PMID:16758605. |
pulmonary tuberculosis was accompanied by lpo activation and intensification of apoptosis in lymphocytes and monocytes. |
2006-09-11 |
2023-08-12 |
Not clear |
| V V Novitskii, A K Strelis, S B Tkachenko, I E Esimova, T A Shil'ko, O I Urazova, O V Voronkova, V A Sinitsina, O V Filinyuk, N A Zemlyanay. LPO and apoptosis during pulmonary tuberculosis. Bulletin of experimental biology and medicine. vol 140. issue 5. 2006-09-11. PMID:16758605. |
the intensity of lipid peroxidation retuned to normal, while activity of apoptosis remained high after therapy. |
2006-09-11 |
2023-08-12 |
Not clear |
| Xiu An Zhan, Min Wang, Zi Rong Xu, Wei Fen Li, Jian Xin L. Evaluation of caspase-dependent apoptosis during fluoride-induced liver lesion in pigs. Archives of toxicology. vol 80. issue 2. 2006-08-24. PMID:16136339. |
the results suggest that fluoride induces apoptosis by elevating the oxidative stress-induced lipid peroxidation, causing mitochondrial dysfunction and further activating caspase-9 and caspase-3. |
2006-08-24 |
2023-08-12 |
Not clear |
| Kota V Ramana, Aruni Bhatnagar, Sanjay Srivastava, Umesh C Yadav, Sanjay Awasthi, Yogesh C Awasthi, Satish K Srivastav. Mitogenic responses of vascular smooth muscle cells to lipid peroxidation-derived aldehyde 4-hydroxy-trans-2-nonenal (HNE): role of aldose reductase-catalyzed reduction of the HNE-glutathione conjugates in regulating cell growth. The Journal of biological chemistry. vol 281. issue 26. 2006-08-18. PMID:16648138. |
products of lipid peroxidation such as 4-hydroxy-trans-2-nonenal (hne) trigger multiple signaling cascades that variably affect cell growth, differentiation, and apoptosis. |
2006-08-18 |
2023-08-12 |
rat |
| Tao Luo, Zhengyuan Xi. A small dose of hydrogen peroxide enhances tumor necrosis factor-alpha toxicity in inducing human vascular endothelial cell apoptosis: reversal with propofol. Anesthesia and analgesia. vol 103. issue 1. 2006-08-16. PMID:16790636. |
increases in apoptosis, bax, lipid peroxidation product malondialdehyde, ldh, and decreases in bcl-2, superoxide dismutase, and glutathione peroxidase were observed in tnf-alpha-treated cells. |
2006-08-16 |
2023-08-12 |
human |
| Tao Luo, Zhengyuan Xi. A small dose of hydrogen peroxide enhances tumor necrosis factor-alpha toxicity in inducing human vascular endothelial cell apoptosis: reversal with propofol. Anesthesia and analgesia. vol 103. issue 1. 2006-08-16. PMID:16790636. |
h2o2 10 microm did not cause significant lipid peroxidation (0.75 +/- 0.03 nmol/mg of malondialdehyde protein) as compared with control (0.70 +/- 0.04 nmol/mg of malondialdehyde protein) (p > 0.05) but further enhanced tnf-alpha-induced lipid peroxidation, upregulated bax, and down-regulated bcl-2 expression and enhanced tnf-alpha-induced cell apoptosis (p < 0.05). |
2006-08-16 |
2023-08-12 |
human |
| Irfan Rahman, Iain Kilt. Antioxidant therapeutic targets in COPD. Current drug targets. vol 7. issue 6. 2006-07-14. PMID:16787173. |
oxidative stress has important consequences for several elements of lung physiology and for the pathogenesis of copd, including oxidative inactivation of antiproteases and surfactants, mucus hypersecretion, membrane lipid peroxidation, alveolar epithelial injury, remodeling of extracellular matrix, and apoptosis. |
2006-07-14 |
2023-08-12 |
Not clear |
| Azize Sener, Derya Ozsavci, Rabia Oba, Gulderen Yanikkaya Demirel, Fikriye Uras, K Turay Yardimc. Do platelet apoptosis, activation, aggregation, lipid peroxidation and platelet-leukocyte aggregate formation occur simultaneously in hyperlipidemia? Clinical biochemistry. vol 38. issue 12. 2006-06-12. PMID:16253220. |
do platelet apoptosis, activation, aggregation, lipid peroxidation and platelet-leukocyte aggregate formation occur simultaneously in hyperlipidemia? |
2006-06-12 |
2023-08-12 |
Not clear |
| Azize Sener, Derya Ozsavci, Rabia Oba, Gulderen Yanikkaya Demirel, Fikriye Uras, K Turay Yardimc. Do platelet apoptosis, activation, aggregation, lipid peroxidation and platelet-leukocyte aggregate formation occur simultaneously in hyperlipidemia? Clinical biochemistry. vol 38. issue 12. 2006-06-12. PMID:16253220. |
the aim of this study was to investigate whether platelet apoptosis, platelet activation, platelet aggregation, platelet-leukocyte aggregate (pla) formation and lipid peroxidation occur simultaneously in hyperlipidemia. |
2006-06-12 |
2023-08-12 |
Not clear |