| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pei-Pei Liu, Shi-Ping Lu, Xiao Li, Gang-Bin Tang, Xiao Liu, Shang-Kun Dai, Lin-Fei Jiao, Xi-Wen Lin, Xing-Guo Li, Baoyang Hu, Jianwei Jiao, Zhao-Qian Teng, Chun-Sheng Han, Chang-Mei Li. Abnormal chromatin remodeling caused by ARID1A deletion leads to malformation of the dentate gyrus. Cell death and differentiation. 2023-08-05. PMID:37543710. |
disruption of arid1a in mouse forebrain significantly decreases neural stem/progenitor cells (nspcs) proliferation and differentiation to neurons within the dentate gyrus (dg), increasing perinatal and postnatal apoptosis, leading to reduced hippocampus size. |
2023-08-05 |
2023-08-14 |
mouse |
| Joshua D Rieskamp, Ileanexis Rosado-Burgos, Jacob E Christofi, Eliza Ansar, Dalia Einstein, Ashley E Walters, Valentina Valentini, John P Bruno, Elizabeth D Kirb. Excitatory amino acid transporter 1 supports adult hippocampal neural stem cell self-renewal. iScience. vol 26. issue 7. 2023-08-03. PMID:37534178. |
within the adult mammalian dentate gyrus (dg) of the hippocampus, glutamate stimulates neural stem cell (nsc) self-renewing proliferation, providing a link between adult neurogenesis and local circuit activity. |
2023-08-03 |
2023-08-14 |
Not clear |
| Parisa Sadat Panahi, Sogol Esmaili, Mohadeseh Ghalandari-Shamami, Zahra Mousavi, Abbas Haghparas. Similar functional roles of the Orexin-1 and Orexin-2 receptors within the dentate gyrus area of the hippocampus in the stress-induced antinociceptive responses in the acute pain model in the rat. Physiology & behavior. 2023-08-03. PMID:37536620. |
some evidence indicates that the hippocampus's dentate gyrus (dg) potentially modulates pain and stress. |
2023-08-03 |
2023-08-14 |
rat |
| Parisa Sadat Panahi, Sogol Esmaili, Mohadeseh Ghalandari-Shamami, Zahra Mousavi, Abbas Haghparas. Similar functional roles of the Orexin-1 and Orexin-2 receptors within the dentate gyrus area of the hippocampus in the stress-induced antinociceptive responses in the acute pain model in the rat. Physiology & behavior. 2023-08-03. PMID:37536620. |
these findings show that the orexin system in the hippocampal dg region might be partially involved in the sia in acute pain. |
2023-08-03 |
2023-08-14 |
rat |
| Daniel D Callow, Yash Kommula, Craig E L Stark, J Carson Smit. Acute cycling exercise and hippocampal subfield function and microstructure in healthy older adults. Hippocampus. 2023-08-01. PMID:37526119. |
aging is associated with deterioration in dentate gyrus (dg) and ca3, both crucial hippocampal subfields for age susceptible memory processes such as mnemonic discrimination (md). |
2023-08-01 |
2023-08-14 |
human |
| Evanthia A Makrygianni, George P Chrouso. Neural Progenitor Cells and the Hypothalamus. Cells. vol 12. issue 14. 2023-07-29. PMID:37508487. |
in the postnatal/adult brain, npcs are primarily located in the subventricular zone (svz) of the lateral ventricles (lvs) and subgranular zone (sgz) of the hippocampal dentate gyrus (dg). |
2023-07-29 |
2023-08-14 |
Not clear |
| Kelsey D McDermott, M Agustina Frechou, Jake T Jordan, Sunaina S Martin, J Tiago Gonçalve. Delayed formation of neural representations of space in aged mice. Aging cell. 2023-07-26. PMID:37491802. |
the hippocampal dentate gyrus (dg) is important for processing spatial information in the brain and is particularly vulnerable to aging, yet its sparse activity has led to difficulties in assessing changes in this area. |
2023-07-26 |
2023-08-14 |
mouse |
| Liming Dong, Ning Jiang, Jie Bai, Yiman Li, Zhihui Song, Xinmin Liu, Chao Zhan. Neuroprotective Effects of Dammarane Sapogenins Against lipopolysaccharide-induced Cognitive Impairment, Neuroinflammation and Synaptic Dysfunction. Neurochemical research. 2023-07-25. PMID:37490197. |
ds also remarkably inhibited lps-induced neuroinflammation by suppressing microglia overactivation, pro-inflammatory cytok ine release (tnf-α and il-1β) and reducing neuronal loss in the ca1 and dg regions of the hippocampus. |
2023-07-25 |
2023-08-14 |
rat |
| Monica Garcia-Durillo, Bruno G Frenguell. Antagonism of P2X7 receptors enhances lorazepam action in delaying seizure onset in an in vitro model of status epilepticus. Neuropharmacology. 2023-07-17. PMID:37459909. |
this study evaluated the effect of the selective p2x7r antagonist a740003 on acute seizures in the dentate gyrus (dg) of hippocampal brain slices, where p2x7rs are highly expressed, with a view to establishing its potential use as a therapy or adjunct with lorazepam (lzp) in refractory se. |
2023-07-17 |
2023-08-14 |
mouse |
| Monica Garcia-Durillo, Bruno G Frenguell. Antagonism of P2X7 receptors enhances lorazepam action in delaying seizure onset in an in vitro model of status epilepticus. Neuropharmacology. 2023-07-17. PMID:37459909. |
extracellular field excitatory postsynaptic potentials were recorded from the dg of male mouse hippocampal slices when spontaneous seizure-like events (sles) were induced by removing extracellular mg |
2023-07-17 |
2023-08-14 |
mouse |
| Si Sun, Yitong Xu, Ningxi Yu, Meifeng Zhang, Jinghui Wang, Dong Wan, Zhen Tian, Huifeng Zh. Catalpol Alleviates Ischemic Stroke Through Promoting Angiogenesis and Facilitating Proliferation and Differentiation of Neural Stem Cells via the VEGF-A/KDR Pathway. Molecular neurobiology. 2023-07-13. PMID:37439957. |
catalpol remarkably promoted angiogenesis, promoted proliferation and differentiation of neural stem cells (nscs) in the subventricular zone (svz), and prevented neuronal loss and astrocyte activation in the ischemic cortex or hippocampal dentate gyrus (dg) in vivo. |
2023-07-13 |
2023-08-14 |
rat |
| Leonardo Oliveira Bittencourt, Aline Dionizio, Maria Karolina Martins Ferreira, Walessa Alana Bragança Aragão, Sabrina de Carvalho Cartágenes, Bruna Puty, Cristiane do Socorro Ferraz Maia, Fatemeh Vida Zohoori, Marília Afonso Rabelo Buzalaf, Rafael Rodrigues Lim. Prolonged exposure to high fluoride levels during adolescence to adulthood elicits molecular, morphological, and functional impairments in the hippocampus. Scientific reports. vol 13. issue 1. 2023-07-08. PMID:37422569. |
these changes were associated with modulation of the hippocampal proteomic profile, especially of proteins related to synaptic communication, and a neurodegenerative pattern in the ca3 and dg. |
2023-07-08 |
2023-08-14 |
mouse |
| Nerina M Villalba, Catalina Madarnas, Julieta Bressano, Viviana Sanchez, Alicia Brusc. Perinatal ethanol exposure affects cell populations in adult dorsal hippocampal neurogenic niche. Neuroscience research. 2023-07-07. PMID:37419388. |
in the adult brain, neurogenesis takes place in the dentate gyrus (dg) of the hippocampus and in the subventricular zone. |
2023-07-07 |
2023-08-14 |
mouse |
| Rafael de Jesús Macias-Velez, Martha Catalina Rivera-Cervantes, Alejandra Guadalupe Marín-López, Justo Murguía-Castill. Intranasal erythropoietin protects granular cells and reduces astrogliosis in the dentate gyrus after ischemic damage, an effect associated with molecular changes in erythropoietin and its receptor. Neuroscience letters. 2023-07-01. PMID:37393008. |
within the hippocampus, the ca1 and dentate gyrus (dg) regions are considered the most and the least susceptible to damage by cerebral ischemia, respectively. |
2023-07-01 |
2023-08-14 |
Not clear |
| Milenna T van Dijk, Ardesheer Talati, Pratik Kashyap, Karan Desai, Nora Kelsall, Marc Gameroff, Natalie Aw, Eyal Abraham, Breda Cullen, Jiook Cha, Christoph Anacker, Myrna M Weissman, Jonathan Posne. Dentate Gyrus Microstructure is associated with Resilience after Exposure to Maternal Stress Across Two Human Cohorts. Biological psychiatry. 2023-07-01. PMID:37393047. |
rodent models implicate the dentate gyrus (dg) of the hippocampus in the effects of ms on offspring depressive-like behaviors, but mechanisms in humans remain unclear. |
2023-07-01 |
2023-08-14 |
human |
| Feng Zhang, Kijun Yoon, Nam-Shik Kim, Guo-Li Ming, Hongjun Son. Cell-autonomous and non-cell-autonomous roles of NKCC1 in regulating neural stem cell quiescence in the hippocampal dentate gyrus. Stem cell reports. 2023-06-30. PMID:37390823. |
how nscs in the dentate gyrus (dg) of the hippocampus acquire their quiescence during early postnatal stages and continuously maintain quiescence in adulthood is poorly understood. |
2023-06-30 |
2023-08-14 |
Not clear |
| Jie Xu, Bowen Zheng, Yanmei Ma, Xiaopeng Zhang, Jianhua Cheng, Jing Yang, Peng Li, Jianzhong Zhang, Li Jing, Fang X. PI3K-AKT-mTOR signaling pathway regulates autophagy of hippocampal neurons in diabetic rats with chronic unpredictable mild stress. Behavioural brain research. 2023-06-30. PMID:37390967. |
the number of pyknotic neurons at cornu ammonis 1 (ca1) and dentate gyrus (dg) of the hippocampus in t2dd was significantly increased compared with cums and t2dm groups. |
2023-06-30 |
2023-08-14 |
rat |
| Rita Chaaya, Joel R Steele, Brian G Oliver, Hui Chen, Rita Machaalan. Effects of e-vapour and high-fat diet on the immunohistochemical staining of nicotinic acetylcholine receptors, apoptosis, microglia and astrocytes in the adult male mouse hippocampus. Journal of chemical neuroanatomy. 2023-06-21. PMID:37343645. |
this study, using a mouse model, investigated the effects of exposure to e-vapour (± nicotine) and hfd (43% fat) consumption, on the expression of nicotinic acetylcholine receptor (nachr) subunits α3, α4, α7 and β2, apoptosis markers caspase-3 and tunel, microglial marker iba-1, and astrocyte marker gfap, in hippocampal subregions of dentate gyrus (dg) and cornu ammonis (ca) 1-3. |
2023-06-21 |
2023-08-14 |
mouse |
| Sanghee Yun, Ivan Soler, Fionya H Tran, Harley A Haas, Raymon Shi, Grace L Bancroft, Maiko Suarez, Christopher R de Santis, Ryan P Reynolds, Amelia J Eisc. Behavioral pattern separation and cognitive flexibility are enhanced in a mouse model of increased lateral entorhinal cortex-dentate gyrus circuit activity. Frontiers in behavioral neuroscience. vol 17. 2023-06-16. PMID:37324519. |
in humans and mice, discrimination and adaptation rely on the integrity of the hippocampal dentate gyrus (dg) which receives glutamatergic input from the entorhinal cortex (ec), including the lateral ec (lec). |
2023-06-16 |
2023-08-14 |
mouse |
| Guo Xiang, Xia Liu, Jiangong Wang, Shunshun Lu, Meng Yu, Yuhan Zhang, Bin Sun, Bin Huang, Xin-Yun Lu, Xingang Li, Di Zhan. Peroxisome proliferator-activated receptor-α activation facilitates contextual fear extinction and modulates intrinsic excitability of dentate gyrus neurons. Translational psychiatry. vol 13. issue 1. 2023-06-15. PMID:37322045. |
the dentate gyrus (dg) of the hippocampus encodes contextual information associated with fear, and cell activity in the dg is required for acquisition and extinction of contextual fear. |
2023-06-15 |
2023-08-14 |
mouse |