| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Matina Tsampoula, Isaak Tarampoulous, Ivi Antoniadou, Yassemi Koutmani, Dimitrios Gkikas, Kostas Vekrellis, Panagiotis K Politi. Nuclear Receptor NR5A2 Promotes Neuronal Identity in the Adult Hippocampus. Molecular neurobiology. vol 58. issue 5. 2021-11-19. PMID:33411242. |
here we show that nr5a2 is differentially expressed in the dg of the adult hippocampus with neurons exhibiting higher levels of expression than adult neural stem/progenitor cells (anscs), suggesting a correlation with neuronal differentiation. |
2021-11-19 |
2023-08-13 |
Not clear |
| Tingting Zhang, Hong Ding, Ya Wang, Zihao Yuan, Yajie Zhang, Guiquan Chen, Yun Xu, Ling Che. Akt3-mTOR regulates hippocampal neurogenesis in adult mouse. Journal of neurochemistry. vol 159. issue 3. 2021-11-19. PMID:34077553. |
akt signaling has been associated with adult neurogenesis in the hippocampal dentate gyrus (dg). |
2021-11-19 |
2023-08-13 |
mouse |
| Tingting Zhang, Hong Ding, Ya Wang, Zihao Yuan, Yajie Zhang, Guiquan Chen, Yun Xu, Ling Che. Akt3-mTOR regulates hippocampal neurogenesis in adult mouse. Journal of neurochemistry. vol 159. issue 3. 2021-11-19. PMID:34077553. |
herein, we show that progenitor cells, neuroblasts, and mature newborn neurons in hippocampal dg expressed akt3 protein. |
2021-11-19 |
2023-08-13 |
mouse |
| Tingting Zhang, Hong Ding, Ya Wang, Zihao Yuan, Yajie Zhang, Guiquan Chen, Yun Xu, Ling Che. Akt3-mTOR regulates hippocampal neurogenesis in adult mouse. Journal of neurochemistry. vol 159. issue 3. 2021-11-19. PMID:34077553. |
the akt3 phosphorylation in hippocampal dg was increased after voluntary wheel running for 7 days in wild-type mice (running wt mice), but not in akt3-ko mice (running akt3-ko mice). |
2021-11-19 |
2023-08-13 |
mouse |
| Roya Homayouni, Qijing Yu, Sruthi Ramesh, Lingfei Tang, Ana M Daugherty, Noa Ofe. Test-retest reliability of hippocampal subfield volumes in a developmental sample: Implications for longitudinal developmental studies. Journal of neuroscience research. vol 99. issue 10. 2021-11-18. PMID:33751637. |
the hippocampus (hc) is composed of cytoarchitectonically distinct subfields: dentate gyrus (dg), cornu ammonis sectors 1-3 (ca1-3), and subiculum. |
2021-11-18 |
2023-08-13 |
Not clear |
| Gen-Lin He, Ze-Ze Wang, Xue-Ting Yu, Ting-Ting Shen, Zhen Luo, Ping Li, Xue Luo, Yu-Long Tan, Peng Gao, Xue-Sen Yan. The involvement of microglial CX3CR1 in heat acclimation-induced amelioration of adult hippocampal neurogenesis impairment in EMF-exposed mice. Brain research bulletin. vol 177. 2021-11-18. PMID:34555433. |
we found that emf exposure significantly decreased the number of proliferating and differentiating cells in the dentate gyrus (dg) of the hippocampus, resulting in a reduced neurogenesis rate. |
2021-11-18 |
2023-08-13 |
mouse |
| Erin L Grafe, Christine J Fontaine, Jennifer D Thomas, Brian R Christi. Effects of prenatal ethanol exposure on choline-induced long-term depression in the hippocampus. Journal of neurophysiology. vol 126. issue 5. 2021-11-17. PMID:34495785. |
in the current work, we study how the direct application of choline can affect synaptic transmission in the dentate gyrus (dg) of hippocampal slices obtained from adolescent ( |
2021-11-17 |
2023-08-13 |
Not clear |
| Cuiqin Fan, Ye Li, Tian Lan, Wenjing Wang, Yifei Long, Shu Yan Y. Microglia secrete miR-146a-5p-containingexosomes to regulate neurogenesis in depression. Molecular therapy : the journal of the American Society of Gene Therapy. 2021-11-17. PMID:34768001. |
enhancing neurogenesis within the hippocampal dentate gyrus (dg) is critical for maintaining brain development and function in many neurological diseases. |
2021-11-17 |
2023-08-13 |
rat |
| Cuiqin Fan, Ye Li, Tian Lan, Wenjing Wang, Yifei Long, Shu Yan Y. Microglia secrete miR-146a-5p-containingexosomes to regulate neurogenesis in depression. Molecular therapy : the journal of the American Society of Gene Therapy. 2021-11-17. PMID:34768001. |
overexpression of mir-146a-5p in hippocampal dg suppresses neurogenesis and spontaneous discharge of excitatory neurons by directly targeting krüppel-like factor 4 (klf4). |
2021-11-17 |
2023-08-13 |
rat |
| Zhigang Xiao, Zhuoqing Cao, Jiali Yang, Zhixia Jia, Yuru Du, Guoqiang Sun, Ye Lu, Lin Pe. Baicalin promotes hippocampal neurogenesis via the Wnt/β-catenin pathway in a chronic unpredictable mild stress-induced mouse model of depression. Biochemical pharmacology. vol 190. 2021-11-16. PMID:33964281. |
the results indicated that baicalin alleviated cums-induced depression-like behaviour, and improved the nerve cells' survival of the hippocampal dentate gyrus (dg) in cums-induced depression of model mice and increased ki-67- and doublecortin (dcx)-positive cells to restore cums-induced suppression of hippocampal neurogenesis. |
2021-11-16 |
2023-08-13 |
mouse |
| Nasrin Hashemi-Firouzi, Siamak Shahidi, Sara Soleimani As. Chronic stimulation of the serotonergic 5-HT4 receptor modulates amyloid-beta-related impairments in synaptic plasticity and memory deficits in male rats. Brain research. vol 1773. 2021-11-12. PMID:34695393. |
hippocampal synaptic plasticity was evaluated in the dentate gyrus (dg) in response to the stimulation applied to the perforant pathway. |
2021-11-12 |
2023-08-13 |
rat |
| Bai-Chuang Shyu, Zhi-Yue Gao, José Jiun-Shian Wu, Alan Bo Han He, Cai-N Cheng, Andrew Chih Wei Huan. Methamphetamine and Modulation Functionality of the Prelimbic Cortex for Developing a Possible Treatment of Alzheimer's Disease in an Animal Model. Frontiers in aging neuroscience. vol 13. 2021-11-10. PMID:34744692. |
furthermore, the excitations or lesions of the prelimbic cortex (prl) can affect mamph-induced cta learning, plasma corticosterone levels, and neural activity or plasticity in the mpfc [i.e., prl, infralimbic cortex (il), cingulate cortex 1 (cg1)], the nac, the amygdala [i.e., basolateral amygdala (bla) and central amygdala (cea)], and the hippocampus [i.e., ca1, ca2, ca3, and dentate gyrus (dg)]. |
2021-11-10 |
2023-08-13 |
rat |
| Bai-Chuang Shyu, Zhi-Yue Gao, José Jiun-Shian Wu, Alan Bo Han He, Cai-N Cheng, Andrew Chih Wei Huan. Methamphetamine and Modulation Functionality of the Prelimbic Cortex for Developing a Possible Treatment of Alzheimer's Disease in an Animal Model. Frontiers in aging neuroscience. vol 13. 2021-11-10. PMID:34744692. |
the mpfc, and particularly the prl and il and the dg of the hippocampus, appeared to show increased neural activity in c-fos expression or neural plasticity in p-erk expression. |
2021-11-10 |
2023-08-13 |
rat |
| Andrew J Kwilasz, Laurel S Todd, Julissa C Duran-Malle, Anouk E W Schrama, Eric H Mitten, Tracey A Larson, Madison A Clements, Kevin M Harris, Scott T Litwiler, Xiaohui Wang, Anne-Marie Van Dam, Steven F Maier, Kenner C Rice, Linda R Watkins, Ruth M Barriento. Experimental autoimmune encephalopathy (EAE)-induced hippocampal neuroinflammation and memory deficits are prevented with the non-opioid TLR2/TLR4 antagonist (+)-naltrexone. Behavioural brain research. vol 396. 2021-11-09. PMID:32905811. |
this was associated with increased mrna for hippocampal interleukin-1β (il-1β), tlr2, tlr4, nlrp3, and il-17 and elevated expression of the microglial marker iba1 in ca1 and dg regions of the hippocampus, confirming the neuroinflammation observed in higher-dose eae models. |
2021-11-09 |
2023-08-13 |
human |
| Mohammad Alipour, Mina Kamkar Asl, Elnaz Khordad, Fatemeh Alipour, Amir Raoofi, Alireza Ebrahimzadeh-Bideskan, Vahid Ebrahim. Histopathological study on neuroapoptotic alterations induced by etomidate in rat hippocampus. Acta histochemica. vol 123. issue 3. 2021-11-08. PMID:33601320. |
our results showed that the number of tunel positive cells and dark neurons (dns) in etomidate group were significantly higher in the ca1, ca2, ca3, and dentate gyrus (dg) of hippocampus compared with the control and normal groups (p < 0.05). |
2021-11-08 |
2023-08-13 |
human |
| Mohammad Alipour, Mina Kamkar Asl, Elnaz Khordad, Fatemeh Alipour, Amir Raoofi, Alireza Ebrahimzadeh-Bideskan, Vahid Ebrahim. Histopathological study on neuroapoptotic alterations induced by etomidate in rat hippocampus. Acta histochemica. vol 123. issue 3. 2021-11-08. PMID:33601320. |
our findings showed that etomidate can increase apoptotic cells and dark neurons induction in different regions of hippocampus mainly in dg. |
2021-11-08 |
2023-08-13 |
human |
| Ye Li, Cuiqin Fan, Liyan Wang, Tian Lan, Rui Gao, Wenjing Wang, Shu Yan Y. MicroRNA-26a-3p rescues depression-like behaviors in male rats via preventing hippocampal neuronal anomalies. The Journal of clinical investigation. vol 131. issue 16. 2021-11-08. PMID:34228643. |
in the present study, we screened microrna (mirna) expression profiles in the dentate gyrus (dg) of the hippocampus and found that mir-26a-3p was markedly downregulated in a rat model of depression, whereas upregulation of mir-26a-3p within dg regions rescued the neuronal deterioration and depression-like phenotypes resulting from stress exposure, effects that appear to be mediated by the pten pathway. |
2021-11-08 |
2023-08-13 |
rat |
| Ye Li, Cuiqin Fan, Liyan Wang, Tian Lan, Rui Gao, Wenjing Wang, Shu Yan Y. MicroRNA-26a-3p rescues depression-like behaviors in male rats via preventing hippocampal neuronal anomalies. The Journal of clinical investigation. vol 131. issue 16. 2021-11-08. PMID:34228643. |
in conclusion, these results suggest that mir-26a-3p deficits within the hippocampal dg mediated the neuronal anomalies contributing to the display of depression-like behaviors. |
2021-11-08 |
2023-08-13 |
rat |
| Wenhua Xu, Hui Li, Caigu He, Jacqueline Frank, Gang Che. Early Ethanol Exposure Inhibits the Differentiation of Hippocampal Dentate Gyrus Granule Cells in a Mouse Model of Fetal Alcohol Spectrum Disorders. Alcoholism, clinical and experimental research. vol 44. issue 5. 2021-11-04. PMID:32220014. |
the hippocampal formation is critically involved in spatial learning/memory and contains 2 major neuron populations: the pyramidal cells in the hippocampus proper and the dentate gyrus granule cells (dggcs) in the dentate gyrus (dg). |
2021-11-04 |
2023-08-13 |
mouse |
| I G Shalaginova, O P Tuchina, M V Sidorova, A S Levina, D A-A Khlebaeva, A I Vaido, N A Dyuzhikov. Effects of psychogenic stress on some peripheral and central inflammatory markers in rats with the different level of excitability of the nervous system. PloS one. vol 16. issue 7. 2021-11-03. PMID:34324596. |
highly excitable animals show an increase in anxiety-like behavior, in the number of neutrophils compared to lymphocytes as well as in the number of iba1+ cells in ca1, ca3 and dg areas of the hippocampus in response to stress. |
2021-11-03 |
2023-08-13 |
rat |