| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fang Yang, Hong Wang, Huali Chen, Dongzhi Ran, Qiang Tang, Ping Weng, Yuzhuo Sun, Wengao Jian. RAGE Signaling pathway in hippocampus dentate gyrus involved in GLT-1 decrease induced by chronic unpredictable stress in rats. Brain research bulletin. vol 163. 2021-09-29. PMID:32621862. |
these findings suggested that rage/creb-nf-κb signaling pathway in hippocampus dg involved in modulation of glt-1 expression, which possibly contributed to the depressive-like behavior induced by cus. |
2021-09-29 |
2023-08-13 |
rat |
| Yihua He, Yuqin Peng, Yuan Chang, Juan Zhu, Zheqi Li, Kaibin Huang, Suyue Pa. Utilizing the Faxitron MultiRad 225 X-ray irradiation system for the construction of mouse chronic whole brain radiation model. Journal of radiation research. 2021-09-29. PMID:34585253. |
however, two months later, the results of immunofluorescence showed that astrocytes and microglia were activated continuously, and the number of immature neurons in dentate gyrus (dg) area of hippocampus was significantly reduced, in accordance with the features of chronic pathophysiological changes. |
2021-09-29 |
2023-08-13 |
mouse |
| Kirsten Hülskötter, Fred Lühder, Alexander Flügel, Vanessa Herder, Wolfgang Baumgärtne. Tamoxifen Application Is Associated with Transiently Increased Loss of Hippocampal Neurons following Virus Infection. International journal of molecular sciences. vol 22. issue 16. 2021-09-24. PMID:34445189. |
thus, tamoxifen application during a tmev infection is associated with transiently increased neuronal loss in the hippocampus, increased reactive astrogliosis and decreased neurogenesis in the dg. |
2021-09-24 |
2023-08-13 |
mouse |
| Eduardo Domínguez-Rivas, Evangelina Ávila-Muñoz, Stephan W Schwarzacher, Angélica Zeped. Adult hippocampal neurogenesis in the context of lipopolysaccharide-induced neuroinflammation: A molecular, cellular and behavioral review. Brain, behavior, and immunity. vol 97. 2021-09-22. PMID:34174334. |
one of these areas is the subgranular zone of the dentate gyrus (dg) in the hippocampus. |
2021-09-22 |
2023-08-13 |
Not clear |
| Eduardo Domínguez-Rivas, Evangelina Ávila-Muñoz, Stephan W Schwarzacher, Angélica Zeped. Adult hippocampal neurogenesis in the context of lipopolysaccharide-induced neuroinflammation: A molecular, cellular and behavioral review. Brain, behavior, and immunity. vol 97. 2021-09-22. PMID:34174334. |
while the dg is associated with contextual and spatial learning and memory, hippocampal neurogenesis is necessary for pattern separation. |
2021-09-22 |
2023-08-13 |
Not clear |
| Gabriel Berdugo-Vega, Chi-Chieh Lee, Alexander Garthe, Gerd Kempermann, Federico Calegar. Adult-born neurons promote cognitive flexibility by improving memory precision and indexing. Hippocampus. vol 31. issue 10. 2021-09-21. PMID:34174010. |
adult neurogenesis in the hippocampal dentate gyrus (dg) is an extraordinary form of plasticity fundamental for cognitive flexibility. |
2021-09-21 |
2023-08-13 |
Not clear |
| Malgorzata Lopatynska-Mazurek, Anna Pankowska, Ewa Gibula-Tarlowska, Radoslaw Pietura, Jolanta H Kotlinsk. Rapamycin Improves Recognition Memory and Normalizes Amino-Acids and Amines Levels in the Hippocampal Dentate Gyrus in Adult Rats Exposed to Ethanol during the Neonatal Period. Biomolecules. vol 11. issue 3. 2021-09-15. PMID:33673489. |
moreover, the effects of rapamycin pre-treatment during neonatal ethanol exposure on the content of amino-acids and amines essential for the proper development of cognitive function in the dentate gyrus (dg) of the hippocampus was evaluated using proton magnetic resonance spectroscopy (1h mrs) in male adult (pnd 60) rats. |
2021-09-15 |
2023-08-13 |
human |
| Kai-Yi Wang, Jei-Wei Wu, Jen-Kun Cheng, Chun-Chung Chen, Wai-Yi Wong, Robert G Averkin, Gábor Tamás, Kazu Nakazawa, Cheng-Chang Lie. Elevation of hilar mossy cell activity suppresses hippocampal excitability and avoidance behavior. Cell reports. vol 36. issue 11. 2021-09-15. PMID:34525354. |
modulation of hippocampal dentate gyrus (dg) excitability regulates anxiety. |
2021-09-15 |
2023-08-13 |
mouse |
| Pierre Wibawa, Florian Kurth, Eileen Luders, Christos Pantelis, Vanessa L Cropley, Maria A Di Biase, Dennis Velakoulis, Mark Walterfan. Differential involvement of hippocampal subfields in Niemann-Pick type C disease: a case-control study. Metabolic brain disease. vol 36. issue 7. 2021-09-14. PMID:34146215. |
gray matter volumes of the cornu ammonis (ca1, ca2 and ca3), dentate gyrus (dg), subiculum, entorhinal cortex and hippocampal-amygdalar transition area were calculated by integrating mri-based image intensities with microscopically defined cytoarchitectonic probabilities. |
2021-09-14 |
2023-08-13 |
Not clear |
| Małgorzata Beręsewicz-Haller, Olga Krupska, Paweł Bochomulski, Danuta Dudzik, Anita Chęcińska, Wojciech Hilgier, Coral Barbas, Krzysztof Zablocki, Barbara Zablock. Mitochondrial Metabolism behind Region-Specific Resistance to Ischemia-Reperfusion Injury in Gerbil Hippocampus. Role of PKCβII and Phosphate-Activated Glutaminase. International journal of molecular sciences. vol 22. issue 16. 2021-09-14. PMID:34445210. |
mitochondria were used to elucidate the endogenous resistance of hippocampal ca2-4 and dentate gyrus (dg) to transient ischemia and reperfusion in a model of ischemic episode in gerbils. |
2021-09-14 |
2023-08-13 |
Not clear |
| Małgorzata Beręsewicz-Haller, Olga Krupska, Paweł Bochomulski, Danuta Dudzik, Anita Chęcińska, Wojciech Hilgier, Coral Barbas, Krzysztof Zablocki, Barbara Zablock. Mitochondrial Metabolism behind Region-Specific Resistance to Ischemia-Reperfusion Injury in Gerbil Hippocampus. Role of PKCβII and Phosphate-Activated Glutaminase. International journal of molecular sciences. vol 22. issue 16. 2021-09-14. PMID:34445210. |
the gerbils hippocampal tissue were isolated at various time of reperfusion and cell lysates or mitochondria were isolated from ca1 and ca2-4,dg hippocampal regions. |
2021-09-14 |
2023-08-13 |
Not clear |
| James P Bauer, Sarah L Rader, Max E Joffe, Wooseok Kwon, Juliana Quay, Leann Seanez, Chengwen Zhou, P Jeffrey Conn, Alan S Lewi. Modeling intrahippocampal effects of anterior hippocampal hyperactivity relevant to schizophrenia using chemogenetic excitation of long axis-projecting mossy cells in the mouse dentate gyrus. Biological psychiatry global open science. vol 1. issue 2. 2021-09-10. PMID:34414387. |
mossy cells (mcs) of the ventral dentate gyrus (dg) densely project in the hippocampal long axis, targeting both dorsal dg granule cells and inhibitory interneurons. |
2021-09-10 |
2023-08-13 |
mouse |
| Yasaman Razavi, Fariborz Keyhanfar, Abbas Haghparast, Ronak Shabani, Mehdi Mehdizade. Cannabidiol promotes neurogenesis in the dentate gyrus during an abstinence period in rats following chronic exposure to methamphetamine. Metabolic brain disease. vol 36. issue 6. 2021-09-09. PMID:34143376. |
to determine whether cannabidiol (cbd) can promote proliferation and maturation of neuronal progenitor cells, this study investigated the cbd effect on neurogenesis in the hippocampal dentate gyrus (dg) following chronic exposure to meth in rats. |
2021-09-09 |
2023-08-13 |
human |
| Saiedeh Arabmoazzen, Mohammad Ali Mirsheka. Evaluation of the effects of metformin as adenosine monophosphate-activated protein kinase activator on spatial learning and memory in a rat model of multiple sclerosis disease. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 141. 2021-09-08. PMID:34323699. |
here, we have tried to study the preservative effects of met as adenosine monophosphate-activated protein kinase (ampk) activator on the hippocampus dentate gyrus (dg) neuronal firing pattern, motor coordination, and learning & memory loss following ms induction. |
2021-09-08 |
2023-08-13 |
rat |
| Saiedeh Arabmoazzen, Mohammad Ali Mirsheka. Evaluation of the effects of metformin as adenosine monophosphate-activated protein kinase activator on spatial learning and memory in a rat model of multiple sclerosis disease. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 141. 2021-09-08. PMID:34323699. |
a neuronal single-unit recording was measured from hippocampus dg. |
2021-09-08 |
2023-08-13 |
rat |
| Pen-Sen Huang, Ping-Yen Tsai, Ling-Yu Yang, Daniela Lecca, Weiming Luo, Dong Seok Kim, Barry J Hoffer, Yung-Hsiao Chiang, Nigel H Greig, Jia-Yi Wan. 3,6'-Dithiopomalidomide Ameliorates Hippocampal Neurodegeneration, Microgliosis and Astrogliosis and Improves Cognitive Behaviors in Rats with a Moderate Traumatic Brain Injury. International journal of molecular sciences. vol 22. issue 15. 2021-09-08. PMID:34361041. |
the number of degenerating neurons in the ca1 and dentate gyrus (dg) regions of the hippocampus after a tbi was reduced by pom and dp. |
2021-09-08 |
2023-08-13 |
rat |
| Katarzyna Głombik, Jan Detka, Bartosz Bobula, Joanna Bąk, Magdalena Kusek, Krzysztof Tokarski, Bogusława Budziszewsk. Contribution of Hypothyroidism to Cognitive Impairment and Hippocampal Synaptic Plasticity Regulation in an Animal Model of Depression. International journal of molecular sciences. vol 22. issue 4. 2021-09-06. PMID:33562494. |
a weakening of memory processes in the wky rats is shown behaviorally, and in the reduction of long-term potentiation (ltp) in the dentate gyrus (dg) and ca1 hippocampal regions. |
2021-09-06 |
2023-08-13 |
rat |
| Rachel K Nauer, Matthew F Dunne, Chantal E Stern, Thomas W Storer, Karin Scho. Improving fitness increases dentate gyrus/CA3 volume in the hippocampal head and enhances memory in young adults. Hippocampus. vol 30. issue 5. 2021-09-02. PMID:31588607. |
the majority of human studies have focused on the potential for exercise to reduce brain atrophy and attenuate cognitive decline in older adults, whereas animal studies often center on exercise-induced neurogenesis and hippocampal plasticity in the dentate gyrus (dg) of young adult animals. |
2021-09-02 |
2023-08-13 |
human |
| Hweeling Lee, Rüdiger Stirnberg, Sichu Wu, Xin Wang, Tony Stöcker, Sonja Jung, Christian Montag, Nikolai Axmache. Genetic Alzheimer's Disease Risk Affects the Neural Mechanisms of Pattern Separation in Hippocampal Subfields. Current biology : CB. vol 30. issue 21. 2021-09-02. PMID:32916120. |
using ultra-high-field (7t) functional magnetic resonance imaging (fmri), apoe-ε3-ε3 carriers predominantly recruited cornu ammonis 3 (ca3) during a spatial mnemonic discrimination task, whereas apoe-ε3-ε4 and apoe-ε3-ε2 carriers engaged ca3 and dentate gyrus (dg) to the same degree. |
2021-09-02 |
2023-08-13 |
Not clear |
| Zhong-Xuan Ma, Ru-Yi Zhang, Wen-Juan Rui, Zhi-Qing Wang, Xia Fen. Quercetin alleviates chronic unpredictable mild stress-induced depressive-like behaviors by promoting adult hippocampal neurogenesis via FoxG1/CREB/ BDNF signaling pathway. Behavioural brain research. vol 406. 2021-09-02. PMID:33745981. |
in addition, to clarify the relationship between quercetin and ahn, we detected neurogenesis markers in the dentate gyrus (dg) of the hippocampus. |
2021-09-02 |
2023-08-13 |
mouse |