| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yuki Hashimotodani, Fuyuki Karube, Yuchio Yanagawa, Fumino Fujiyama, Masanobu Kan. Supramammillary Nucleus Afferents to the Dentate Gyrus Co-release Glutamate and GABA and Potentiate Granule Cell Output. Cell reports. vol 25. issue 10. 2019-11-13. PMID:30517859. |
the supramammillary nucleus (sum) of the hypothalamus projects to the dentate gyrus (dg) and the ca2 region of the hippocampus. |
2019-11-13 |
2023-08-13 |
Not clear |
| Sara Bonzano, Isabella Crisci, Anna Podlesny-Drabiniok, Chiara Rolando, Wojciech Krezel, Michèle Studer, Silvia De Marchi. Neuron-Astroglia Cell Fate Decision in the Adult Mouse Hippocampal Neurogenic Niche Is Cell-Intrinsically Controlled by COUP-TFI In Vivo. Cell reports. vol 24. issue 2. 2019-11-07. PMID:29996095. |
in the dentate gyrus (dg) of the mouse hippocampus, neurogenesis and astrogliogenesis persist throughout life. |
2019-11-07 |
2023-08-13 |
mouse |
| Dongning Su, Hui Liu, Tianrong Liu, Xin Zhang, Wei Yang, Yizhi Song, Jinping Liu, Yan Wu, Lirong Chan. Dynamic SAP102 expression in the hippocampal subregions of rats and APP/PS1 mice of various ages. Journal of anatomy. vol 232. issue 6. 2019-11-06. PMID:29574717. |
in wistar rats, sap102 was not only highly expressed in the hippocampal subregions of neonatal rats but also maintained relatively high expression levels in adult hippocampi and displayed no obvious decreases in the ca1 and dg subregions of aged rats. |
2019-11-06 |
2023-08-13 |
mouse |
| Joanna Ruth Appel, Shiyang Ye, Fulei Tang, Dong Sun, Hongsheng Zhang, Lin Mei, Wen-Cheng Xion. Increased Microglial Activity, Impaired Adult Hippocampal Neurogenesis, and Depressive-like Behavior in Microglial VPS35-Depleted Mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 38. issue 26. 2019-10-28. PMID:29853629. |
conditional knocking out of vps35 in microglia of male mice results in regionally increased microglial density and activity in the subgranular zone of the hippocampal dentate gyrus (dg), accompanied by elevated neural progenitor proliferation, but decreased neuronal differentiation. |
2019-10-28 |
2023-08-13 |
mouse |
| Khushboo Srivastava, Ratnakar Tripathi, Rajnikant Mishr. Age-dependent alterations in expression and co-localization of Pax6 and Ras-GAP in brain of aging mice. Journal of chemical neuroanatomy. vol 92. 2019-10-22. PMID:29787792. |
the co-localization of pax6 and ras-gap were observed in dentate gyrus (dg) and sub-granular zone (sgz) of hippocampus, in glomerular (glla) and mitral cells (mice) of olfactory lobe, granular cells (grce), purkinje cell (puce) and molecular cell layer (mola) of cerebellum, internal plexiform layer (inpl), molecular layer (mola) of cerebral cortex and in intercalated cells of amygdala (itc), caudate nucleus regions in brain of aging mice. |
2019-10-22 |
2023-08-13 |
mouse |
| Lisa Müller-Ehrenberg, Joost M Riphagen, Frans R J Verhey, Alexander T Sack, Heidi I L Jacob. Alzheimer's Disease Biomarkers Have Distinct Associations with Specific Hippocampal Subfield Volumes. Journal of Alzheimer's disease : JAD. vol 66. issue 2. 2019-10-08. PMID:30320590. |
the present study investigated the relationship of aβ and p-tau with hippocampal subfield volumes cornu ammonis (ca) 1-4, dentate gyrus (dg), and subiculum. |
2019-10-08 |
2023-08-13 |
human |
| Daniele Poli, Bruce C Wheeler, Thomas B DeMarse, Gregory J Brewe. Pattern separation and completion of distinct axonal inputs transmitted via micro-tunnels between co-cultured hippocampal dentate, CA3, CA1 and entorhinal cortex networks. Journal of neural engineering. vol 15. issue 4. 2019-10-04. PMID:29623900. |
functions ascribed to the hippocampal sub-regions for encoding episodic memories include the separation of activity patterns propagated from the entorhinal cortex (ec) into the dentate gyrus (dg) and pattern completion in ca3 region. |
2019-10-04 |
2023-08-13 |
Not clear |
| Li-Na Sun, Jin-Shun Qi, Rong Ga. Physical exercise reserved amyloid-beta induced brain dysfunctions by regulating hippocampal neurogenesis and inflammatory response via MAPK signaling. Brain research. vol 1697. 2019-09-27. PMID:29729254. |
morphological studies reveal physical exercise increased the adult neurogenesis and release the immune-response in hippocampal dentate gyrus (dg) region. |
2019-09-27 |
2023-08-13 |
mouse |
| Magdalena Miranda, Brianne A Kent, Juan Facundo Morici, Francisco Gallo, Lisa M Saksida, Timothy J Bussey, Noelia Weisstaub, Pedro Bekinschtei. NMDA receptors and BDNF are necessary for discrimination of overlapping spatial and non-spatial memories in perirhinal cortex and hippocampus. Neurobiology of learning and memory. vol 155. 2019-09-23. PMID:30172952. |
discrimination of overlapping representations has been investigated in the dentate gyrus (dg) of the hippocampus and largely in the perirhinal cortex (prh). |
2019-09-23 |
2023-08-13 |
Not clear |
| Yuan Gao, En-Jie Liu, Wei-Jin Wang, Ya-Li Wang, Xiao-Guang Li, Xin Wang, Shi-Hong Li, Shu-Juan Zhang, Meng-Zhu Li, Qiu-Zhi Zhou, Xiao-Bing Long, Hua-Qiu Zhang, Jian-Zhi Wan. Microglia CREB-Phosphorylation Mediates Amyloid-β-Induced Neuronal Toxicity. Journal of Alzheimer's disease : JAD. vol 66. issue 1. 2019-09-19. PMID:30282353. |
aβ treatment for 24 h increased ps133-creb level in microglia of the hippocampal non-granular cell layers with remarkably decreased ps133-creb immunoreactivity in neurons of the hippocampal granular cell layers, including ca1, ca3, and dg subsets. |
2019-09-19 |
2023-08-13 |
mouse |
| Chao Dong, Ji-Chun Zhang, Qian Ren, Min Ma, Youge Qu, Kai Zhang, Wei Yao, Tamaki Ishima, Hisashi Mori, Kenji Hashimot. Deletion of serine racemase confers D-serine -dependent resilience to chronic social defeat stress. Neurochemistry international. vol 116. 2019-09-10. PMID:29550603. |
in wt mice, csds decreased brain-derived neurotrophic factor (bdnf) expression and phosphorylation/activation of its receptor trkb in prefrontal cortex (pfc), dentate gyrus (dg), and the ca3 region of the hippocampus, but increased bdnf and phosphorylated trkb in the nucleus accumbens (nac). |
2019-09-10 |
2023-08-13 |
mouse |
| S Y Yau, Luis Bettio, M Vetrici, A Truesdell, C Chiu, J Chiu, E Truesdell, B R Christi. Chronic minocycline treatment improves hippocampal neuronal structure, NMDA receptor function, and memory processing in Fmr1 knockout mice. Neurobiology of disease. vol 113. 2019-09-06. PMID:29367010. |
previously we have shown that fxs results in learning impairments that involve deficits in n-methyl-d-aspartate (nmda) receptor-dependent synaptic plasticity in the hippocampal dentate gyrus (dg). |
2019-09-06 |
2023-08-13 |
mouse |
| Anindita Sarkar, Arianna Mei, Apua C M Paquola, Shani Stern, Cedric Bardy, Jason R Klug, Stacy Kim, Neda Neshat, Hyung Joon Kim, Manching Ku, Maxim N Shokhirev, David H Adamowicz, Maria C Marchetto, Roberto Jappelli, Jennifer A Erwin, Krishnan Padmanabhan, Matthew Shtrahman, Xin Jin, Fred H Gag. Efficient Generation of CA3 Neurons from Human Pluripotent Stem Cells Enables Modeling of Hippocampal Connectivity In Vitro. Cell stem cell. vol 22. issue 5. 2019-09-05. PMID:29727680. |
this differentiation paradigm exhibits characteristics of neuronal network maturation, and rabies virus tracing revealed synaptic connections between stem cell-derived dentate gyrus (dg) and ca3 neurons in vitro recapitulating the neuronal connectivity within the hippocampus. |
2019-09-05 |
2023-08-13 |
human |
| Anindita Sarkar, Arianna Mei, Apua C M Paquola, Shani Stern, Cedric Bardy, Jason R Klug, Stacy Kim, Neda Neshat, Hyung Joon Kim, Manching Ku, Maxim N Shokhirev, David H Adamowicz, Maria C Marchetto, Roberto Jappelli, Jennifer A Erwin, Krishnan Padmanabhan, Matthew Shtrahman, Xin Jin, Fred H Gag. Efficient Generation of CA3 Neurons from Human Pluripotent Stem Cells Enables Modeling of Hippocampal Connectivity In Vitro. Cell stem cell. vol 22. issue 5. 2019-09-05. PMID:29727680. |
because hippocampal dysfunction has been implicated in schizophrenia, we applied dg and ca3 differentiation paradigms to schizophrenia-patient-derived hipscs. |
2019-09-05 |
2023-08-13 |
human |
| Jonika Tannous, Henrique Amaral-Silva, Bo Cao, Mon-Ju Wu, Giovana B Zunta-Soares, Iram Kazimi, Cristian Zeni, Benson Mwangi, Jair C Soare. Hippocampal subfield volumes in children and adolescents with mood disorders. Journal of psychiatric research. vol 101. 2019-09-02. PMID:29550609. |
indeed, adult studies have reported smaller hippocampal subfield volumes in regions within the cornu ammonis (ca1 and ca4), dentate gyrus (dg), and hippocampal tails in both patients with major depressive disorder (mdd) and bipolar disorder (bd) compared to healthy controls. |
2019-09-02 |
2023-08-13 |
Not clear |
| Maryam Eslami, Bahman Sadeghi, Fatemeh Goshadro. Chronic ghrelin administration restores hippocampal long-term potentiation and ameliorates memory impairment in rat model of Alzheimer's disease. Hippocampus. vol 28. issue 10. 2019-08-26. PMID:30009391. |
here, we investigated the neuroprotective and therapeutic effects of intracerebroventricular (icv) ghrelin infusion for 2 weeks on passive avoidance learning (pal), memory retention, and synaptic plasticity in the hippocampal dentate gyrus (dg) and ca1 of both normal rats and aβ1-42-induced neurotoxicity in ad model. |
2019-08-26 |
2023-08-13 |
human |
| Katherine G Akers, Yoan Chérasse, Yuki Fujita, Sakthivel Srinivasan, Takeshi Sakurai, Masanori Sakaguch. Concise Review: Regulatory Influence of Sleep and Epigenetics on Adult Hippocampal Neurogenesis and Cognitive and Emotional Function. Stem cells (Dayton, Ohio). vol 36. issue 7. 2019-08-20. PMID:29484772. |
one of these neurogenic regions is the dentate gyrus (dg) of the hippocampus, which plays an important role in cognition and emotion. |
2019-08-20 |
2023-08-13 |
Not clear |
| Maura Boldrini, Camille A Fulmore, Alexandria N Tartt, Laika R Simeon, Ina Pavlova, Verica Poposka, Gorazd B Rosoklija, Aleksandar Stankov, Victoria Arango, Andrew J Dwork, René Hen, J John Man. Human Hippocampal Neurogenesis Persists throughout Aging. Cell stem cell. vol 22. issue 4. 2019-08-14. PMID:29625071. |
aging humans are thought to exhibit waning neurogenesis and exercise-induced angiogenesis, with a resulting volumetric decrease in the neurogenic hippocampal dentate gyrus (dg) region, although concurrent changes in these parameters are not well studied. |
2019-08-14 |
2023-08-13 |
human |
| Pradeep Punnakkal, Deity Domini. NMDA Receptor GluN2 Subtypes Control Epileptiform Events in the Hippocampus. Neuromolecular medicine. vol 20. issue 1. 2019-08-13. PMID:29335819. |
epileptiform events (efes) were recorded from the ca1 and dg areas of hippocampus with or without subtype-specific antagonists. |
2019-08-13 |
2023-08-13 |
rat |
| Jawad Fares, Zeina Bou Diab, Sanaa Nabha, Youssef Fare. Neurogenesis in the adult hippocampus: history, regulation, and prospective roles. The International journal of neuroscience. vol 129. issue 6. 2019-08-12. PMID:30433866. |
abbreviations ahn adult hippocampal neurogenesis akt protein kinase b bmp bone morphogenic protein brdu bromodeoxyuridine cns central nervous system dg dentate gyrus disc1 disrupted-in-schizophrenia 1 fgf-2 fibroblast growth factor 2 gaba gamma-aminobutyric acid mbd1 methyl-cpg-binding domain protein 1 mecp2 methyl-cpg-binding protein 2 mtor mammalian target of rapamycin nscs neural stem cells ob olfactory bulb; p21: cyclin-dependent kinase inhibitor 1 rbpj recombination signal binding protein for immunoglobulin kappa j region rms rostral migratory stream sgz subgranular zone shh sonic hedgehog sox2 sry (sex determining region y)-box 2 svz subventricular zone wnt3 wingless-type mouse mammary tumor virus. |
2019-08-12 |
2023-08-13 |
mouse |