| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Irena Majkutewicz, Ewelina Kurowska, Magdalena Podlacha, Dorota Myślińska, Beata Grembecka, Jan Ruciński, Karolina Pierzynowska, Danuta Wron. Age-dependent effects of dimethyl fumarate on cognitive and neuropathological features in the streptozotocin-induced rat model of Alzheimer's disease. Brain research. vol 1686. 2019-04-19. PMID:29453958. |
notably, within aged stz-injected rats, dmf treatment was associated with improved performance in mwm, reduced neurodegeneration in all hippocampal areas, reduced dg microglia activation, and reduced ca1 nitrotyrosine labeling compared to age-matched rats without dmf treatment. |
2019-04-19 |
2023-08-13 |
rat |
| Siok Lam Lim, Diana Nguyen Tran, Joannee Zumkehr, Christine Chen, Sagar Ghiaar, Zanett Kieu, Emmanuel Villanueva, Victoria Gallup, Carlos J Rodriguez-Ortiz, Masashi Kitazaw. Inhibition of hematopoietic cell kinase dysregulates microglial function and accelerates early stage Alzheimer's disease-like neuropathology. Glia. vol 66. issue 12. 2019-04-15. PMID:30277607. |
these multifactorial changes in microglial activities led to attenuated psd95 levels in hippocampal dg and ca3 regions, but did not alter the postsynaptic dendritic spine morphology at the ca1 region nor cognitive function of the mice. |
2019-04-15 |
2023-08-13 |
mouse |
| Baohui Zhai, Xueliang Shang, Jingxuan Fu, Fangjuan Li, Tao Zhan. Rapamycin relieves anxious emotion and synaptic plasticity deficits induced by hindlimb unloading in mice. Neuroscience letters. vol 677. 2019-04-09. PMID:29684531. |
afterwards, long-term potentiation (ltp) recorded in the hippocampal dentate gyrus (dg) region was effectively reduced by rapamycin, which was significantly inhibited by hu procedure. |
2019-04-09 |
2023-08-13 |
mouse |
| Shuang-Hong Tang, Yan-Jun Du, Jia-Huan Xiao, Yun Wang, Feng Shen, Guo-Jie Su. [Acupuncture and Moxibustion Improves Learning-memory Ability of Alzheimer's Disease Rats Possibly by Up-regulating Serum Aβ Internalization Enzyme Contents]. Zhen ci yan jiu = Acupuncture research. vol 43. issue 11. 2019-04-08. PMID:30585465. |
to observe the effect of acupuncture and moxibustion (am) on learning-memory ability and expression of amyloid beta (aβ) in the hippocampal dentate gyrus (dg) of alzheimer's disease (ad) rats, so as to explore its mechanism underlying improvement of ad. |
2019-04-08 |
2023-08-13 |
rat |
| Sita Sharan Patel, R S Ray, Arun Sharma, Vineet Mehta, Anju Katyal, Malairaman Udayaban. Antidepressant and anxiolytic like effects of Urtica dioica leaves in streptozotocin induced diabetic mice. Metabolic brain disease. vol 33. issue 4. 2019-04-01. PMID:29704081. |
in addition, chronic diabetes significantly increased the expression of tnf-α in ca1 (p < 0.001), ca2 (p < 0.01), ca3 (p < 0.001) and dg (p < 0.001) regions of hippocampus as compared to control mice. |
2019-04-01 |
2023-08-13 |
mouse |
| Sita Sharan Patel, R S Ray, Arun Sharma, Vineet Mehta, Anju Katyal, Malairaman Udayaban. Antidepressant and anxiolytic like effects of Urtica dioica leaves in streptozotocin induced diabetic mice. Metabolic brain disease. vol 33. issue 4. 2019-04-01. PMID:29704081. |
chronic diabetes mediated neuronal damage in the ca2, ca3 and dg regions of hippocampus. |
2019-04-01 |
2023-08-13 |
mouse |
| b' Andrijana Stanisavljevi\\xc4\\x87, Ivana Peri\\xc4\\x87, Peter Gass, Dragos Inta, Undine E Lang, Stefan Borgwardt, Dragana Filipovi\\xc4\\x8. Brain Sub/Region-Specific Effects of Olanzapine on c-Fos Expression of Chronically Socially Isolated Rats. Neuroscience. vol 396. 2019-04-01. PMID:30458222.' |
olz treatment reversed depression- and anxiety-like behaviors induced by csis and suppressed a csis-induced increase in the number of c-fos-positive cells in subregions of the dorsal hippocampus, ventral (v) dg, retrosplenial cortex, and medial prefrontal cortex. |
2019-04-01 |
2023-08-13 |
rat |
| Talita Matias Barbosa Cavalcante, José de Maria Albuquerque De Melo, Lia Bastos Lopes, Matheus Costa Bessa, Jéssica Gurgel Santos, Luna Costa Vasconcelos, Antônio Eufrásio Vieira Neto, Lucas Teixeira Nunes Borges, Marta Maria França Fonteles, Adriano José Maia Chaves Filho, Danielle Macêdo, Adriana Rolim Campos, Carlos Clayton Torres Aguiar, Silvânia Maria Mendes Vasconcelo. Ivabradine possesses anticonvulsant and neuroprotective action in mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 109. 2019-04-01. PMID:30551511. |
immunohistochemistry analysis for cleaved caspase-3, a pro-apoptotic and degenerative marker, in hippocampal subregions namely cornu ammonis (ca)1, ca3 and dentate gyrus (dg), were also performed. |
2019-04-01 |
2023-08-13 |
mouse |
| Simone F Carron, Edwin B Yan, Benjamin J Allitt, Ramesh Raja. Immediate and Medium-term Changes in Cortical and Hippocampal Inhibitory Neuronal Populations after Diffuse TBI. Neuroscience. vol 388. 2019-03-29. PMID:30036662. |
however, dg of hippocampus now showed reduction of dendrite-targeting inhibitory neurons. |
2019-03-29 |
2023-08-13 |
Not clear |
| Yuta Senza. Function of local circuits in the hippocampal dentate gyrus-CA3 system. Neuroscience research. vol 140. 2019-03-28. PMID:30408501. |
anatomical observations, theoretical work and lesioning experiments have supported the idea that the ca3 in the hippocampus is important for encoding, storage and retrieval of memory while the dentate gyrus (dg) is important for the pattern separation of the incoming inputs from the entorhinal cortex. |
2019-03-28 |
2023-08-13 |
Not clear |
| Ali Sayyahi, Mehrdad Jahanshahi, Hossein Amini, Hamid Sepehr. Vitamin E can compensate the density of M1 receptors in the hippocampus of scopolamine-treated rats. Folia neuropathologica. vol 56. issue 3. 2019-03-28. PMID:30509043. |
vitamin e treatment significantly increased neuron numbers in the ca1 and ca3 areas of the hippocampus and dg area. |
2019-03-28 |
2023-08-13 |
rat |
| Sahreh Shabani, Mohammad Ali Mirsheka. Diosmin is neuroprotective in a rat model of scopolamine-induced cognitive impairment. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 108. 2019-03-22. PMID:30372840. |
in this study, we have assessed the effects of administration of the diosmin (dm, 50 and 100 mg/kg), before injection of 0.4 mg/kg of scopolamine on memory and motor function, the hippocampal dentate gyrus (dg) electrophysiological activity as well as brain inflammation. |
2019-03-22 |
2023-08-13 |
rat |
| S Stern, R Santos, M C Marchetto, A P D Mendes, G A Rouleau, S Biesmans, Q-W Wang, J Yao, P Charnay, A G Bang, M Alda, F H Gag. Neurons derived from patients with bipolar disorder divide into intrinsically different sub-populations of neurons, predicting the patients' responsiveness to lithium. Molecular psychiatry. vol 23. issue 6. 2019-03-18. PMID:28242870. |
we recently reported that hippocampal dentate gyrus (dg) neurons differentiated from induced pluripotent stem cell (ipsc)-derived fibroblasts of bd patients are electrophysiologically hyperexcitable. |
2019-03-18 |
2023-08-13 |
human |
| Dinesh Upadhya, Bharathi Hattiangady, Olagide W Castro, Bing Shuai, Maheedhar Kodali, Sahithi Attaluri, Adrian Bates, Yi Dong, Su-Chun Zhang, Darwin J Prockop, Ashok K Shett. Human induced pluripotent stem cell-derived MGE cell grafting after status epilepticus attenuates chronic epilepsy and comorbidities via synaptic integration. Proceedings of the National Academy of Sciences of the United States of America. vol 116. issue 1. 2019-03-18. PMID:30559206. |
moreover, grafting of hipsc-mge cells after se mediated several neuroprotective and antiepileptogenic effects in the host hippocampus, as evidenced by reductions in host interneuron loss, abnormal neurogenesis, and aberrant mossy fiber sprouting in the dentate gyrus (dg). |
2019-03-18 |
2023-08-13 |
human |
| Dinesh Upadhya, Bharathi Hattiangady, Olagide W Castro, Bing Shuai, Maheedhar Kodali, Sahithi Attaluri, Adrian Bates, Yi Dong, Su-Chun Zhang, Darwin J Prockop, Ashok K Shett. Human induced pluripotent stem cell-derived MGE cell grafting after status epilepticus attenuates chronic epilepsy and comorbidities via synaptic integration. Proceedings of the National Academy of Sciences of the United States of America. vol 116. issue 1. 2019-03-18. PMID:30559206. |
furthermore, axons from graft-derived interneurons made synapses on the dendrites of host excitatory neurons in the dg and the ca1 subfield of the hippocampus, implying an excellent graft-host synaptic integration. |
2019-03-18 |
2023-08-13 |
human |
| A Kanzari, C Bourcier-Lucas, A Freyssin, D N Abrous, N Haddjeri, G Luca. Inducing a long-term potentiation in the dentate gyrus is sufficient to produce rapid antidepressant-like effects. Molecular psychiatry. vol 23. issue 3. 2019-03-12. PMID:28485406. |
recent hypotheses propose that one prerequisite to obtain a rapid antidepressant (ad) effect would reside in processes of synaptic reinforcement occurring within the dentate gyrus (dg) of the hippocampus independently from neurogenesis. |
2019-03-12 |
2023-08-13 |
rat |
| Huan Zhu, Lixing Qiao, Yao Sun, Liping Yin, Li Huang, Li Jiang, Jiaqing L. Basic fibroblast growth factor enhances cell proliferation in the dentate gyrus of neonatal rats following hypoxic-ischemic brain damage. Neuroscience letters. vol 673. 2019-03-11. PMID:29410360. |
the present study aimed to investigate the correlation between neurogenesis and basic fibroblast growth factor (bfgf) in the hippocampal dentate gyrus (dg) region in neonatal rats following hibd. |
2019-03-11 |
2023-08-13 |
rat |
| Rui Zhu, Yi-Hsuan Pan, Lijie Sun, Tianhao Zhang, Caiyun Wang, Shuai Ye, Ning Yang, Tiantian Lu, Thomas Wisniewski, Suying Dang, Wei Zhan. ADAMTS18 Deficiency Affects Neuronal Morphogenesis and Reduces the Levels of Depression-like Behaviors in Mice. Neuroscience. vol 399. 2019-03-11. PMID:30579834. |
in this study, we showed that adamts18 mrna is highly abundant in developing brains, especially in the cerebellum granular cell layer and the hippocampus dentate gyrus (dg) granular cell layer. |
2019-03-11 |
2023-08-13 |
mouse |
| Rui Zhu, Yi-Hsuan Pan, Lijie Sun, Tianhao Zhang, Caiyun Wang, Shuai Ye, Ning Yang, Tiantian Lu, Thomas Wisniewski, Suying Dang, Wei Zhan. ADAMTS18 Deficiency Affects Neuronal Morphogenesis and Reduces the Levels of Depression-like Behaviors in Mice. Neuroscience. vol 399. 2019-03-11. PMID:30579834. |
adamts18 knockout (ko) mice displayed higher dendritic branching complexity and spine density on hippocampal dg granular cells. |
2019-03-11 |
2023-08-13 |
mouse |
| A Dheer, V Jain, N Kushwah, R Kumar, D Prasad, S B Sing. Temporal and Spatial Changes in Glial Cells During Chronic Hypobaric Hypoxia: Role in Neurodegeneration. Neuroscience. vol 383. 2019-03-07. PMID:29751055. |
the study aims to understand the effect of hh exposure on glial physiology in a time-dependent (0, 1, 3, 7 and 14 days of hh exposure) and region-dependent (ca1, ca3 and dg regions of hippocampus) manner. |
2019-03-07 |
2023-08-13 |
Not clear |