| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yuan Fang, Hui Li, Lirong Chang, Yizhi Song, Longhui Ma, Liying Lu, Zunshu Du, Yan Li, Jinping Liu, Yan W. Prenatal stress induced gender-specific alterations of N-methyl-d-aspartate receptor subunit expression and response to Aβ in offspring hippocampal cells. Behavioural brain research. vol 336. 2018-06-01. PMID:28855140. |
in the present study, we tried to explore whether ps affects offspring's aβ levels and nmdar subunit expression in a gender-specific manner in hippocampal ca and dg subregions, and whether ps affects synaptic proteins and nmdar subunit expression in cultured offspring hippocampal cells exposed to aβ. |
2018-06-01 |
2023-08-13 |
rat |
| Trevor A Steve, Clarissa L Yasuda, Roland Coras, Mohjevan Lail, Ingmar Blumcke, Daniel J Livy, Nikolai Malykhin, Donald W Gros. Development of a histologically validated segmentation protocol for the hippocampal body. NeuroImage. vol 157. 2018-05-28. PMID:28587896. |
in the present study, we aimed to: 1) develop a novel method for hippocampal body segmentation, based on two mri-visible anatomical landmarks (stratum lacunosum moleculare [slm] & dentate gyrus [dg]), and assess its accuracy in comparison to the gold standard direct histological measurements; 2) quantify the accuracy of two published segmentation strategies in comparison to the histological gold standard; and 3) apply the novel method to ex vivo mri and correlate the results with histology. |
2018-05-28 |
2023-08-13 |
human |
| Jing Lv, Hao Feng, Ling Chen, Wei-Yao Wang, Xue-Ling Yue, Qing-Hua Ji. Activation of β-adrenoceptor facilitates active avoidance learning through enhancement of glutamate levels in the hippocampal dentate gyrus. Neuroreport. vol 28. issue 15. 2018-05-23. PMID:28877104. |
despite a number of studies indicating that β-adrenoceptors in the hippocampal dentate gyrus (dg) is involved in the modulation of learning and memory as well as ltp, few studies have used glutamate release as a visual indicator in awake animals to explore the role of β-adrenoceptors in learning-dependent ltp. |
2018-05-23 |
2023-08-13 |
rat |
| Jing Lv, Hao Feng, Ling Chen, Wei-Yao Wang, Xue-Ling Yue, Qing-Hua Ji. Activation of β-adrenoceptor facilitates active avoidance learning through enhancement of glutamate levels in the hippocampal dentate gyrus. Neuroreport. vol 28. issue 15. 2018-05-23. PMID:28877104. |
our results suggest that activation of β-adrenoceptors in the hippocampal dg facilitates active avoidance learning by modulations of glutamate level and synaptic efficiency in rats. |
2018-05-23 |
2023-08-13 |
rat |
| Taysa B Bassani, Joelle M Turnes, Eric L R Moura, Jéssica M Bonato, Valentín Cóppola-Segovia, Silvio M Zanata, Rúbia M M W Oliveira, Maria A B F Vita. Effects of curcumin on short-term spatial and recognition memory, adult neurogenesis and neuroinflammation in a streptozotocin-induced rat model of dementia of Alzheimer's type. Behavioural brain research. vol 335. 2018-05-22. PMID:28801114. |
four weeks after surgery, stz-lesioned animals exhibited impairments in short-term spatial memory (object location test (olt) and y maze) and short-term recognition memory (object recognition test - ort), decreased cell proliferation and immature neurons (ki-67- and doublecortin-positive cells, respectively) in the subventricular zone (svz) and dentate gyrus (dg) of hippocampus, and increased immunoreactivity for the glial markers gfap and iba-1 (neuroinflammation). |
2018-05-22 |
2023-08-13 |
rat |
| David Briley, Valeria Ghirardi, Randy Woltjer, Alicia Renck, Olga Zolochevska, Giulio Taglialatela, Maria-Adelaide Micc. Preserved neurogenesis in non-demented individuals with AD neuropathology. Scientific reports. vol 6. 2018-05-18. PMID:27298190. |
laser-capture microdissection of autopsy human hippocampus dg and qrt-pcr mirna analyses were combined with immunofluorescence in this study. |
2018-05-18 |
2023-08-13 |
human |
| Theresa Currier Thomas, Joshua A Beitchman, Francois Pomerleau, Teresa Noel, Paiboon Jungsuwadee, D Allan Butterfield, Daret K St Clair, Mary Vore, Greg A Gerhard. Acute treatment with doxorubicin affects glutamate neurotransmission in the mouse frontal cortex and hippocampus. Brain research. vol 1672. 2018-05-18. PMID:28705715. |
using novel glutamate-selective microelectrode arrays, amperometric recordings measured parameters of extracellular glutamate clearance and potassium-evoked release of glutamate within the medial fc and dentate gyrus (dg) of the hippocampus. |
2018-05-18 |
2023-08-13 |
mouse |
| Chantelle E Terrillion, Bagrat Abazyan, Zhongxi Yang, Joshua Crawford, Alexey V Shevelkin, Yan Jouroukhin, Ki Hyun Yoo, Chang Hoon Cho, Robin Roychaudhuri, Solomon H Snyder, Mi-Hyeon Jang, Mikhail V Pletniko. DISC1 in Astrocytes Influences Adult Neurogenesis and Hippocampus-Dependent Behaviors in Mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 11. 2018-05-16. PMID:28631721. |
as both astrocytes and disc1 influence adult neurogenesis in the dentate gyrus (dg) of the hippocampus, we hypothesized that selective expression of dominant-negative c-terminus-truncated human disc1 (mutant disc1) in astrocytes would affect adult hippocampal neurogenesis and hippocampus-dependent behaviors. |
2018-05-16 |
2023-08-13 |
mouse |
| Ioanna Dori, Spyros Petrakis, Aggeliki Giannakopoulou, Chryssa Bekiari, Ioannis Grivas, Evangelia K Siska, Georgios Koliakos, Georgios C Papadopoulo. Seven days post-injury fate and effects of genetically labelled adipose-derived mesenchymal cells on a rat traumatic brain injury experimental model. Histology and histopathology. vol 32. issue 10. 2018-05-15. PMID:28035654. |
venus+ascs stimulated the proliferation of endogenous neural stem cells (nscs) in the brain neurogenic niches, the subventricular zone (svz) and the hippocampal dentate gyrus (dg). |
2018-05-15 |
2023-08-13 |
rat |
| Junli Zhen, Yanjing Qian, Jian Fu, Ruijun Su, Haiting An, Wei Wang, Yan Zheng, Xiaomin Wan. Deep Brain Magnetic Stimulation Promotes Neurogenesis and Restores Cholinergic Activity in a Transgenic Mouse Model of Alzheimer's Disease. Frontiers in neural circuits. vol 11. 2018-05-02. PMID:28713248. |
furthermore, neurogenesis in the hippocampal dg of dms-treated 5xfad mice was clearly enhanced. |
2018-05-02 |
2023-08-13 |
mouse |
| Nuno R Ferreira, Ana Ledo, João Laranjinha, Greg A Gerhardt, Rui M Barbos. Simultaneous measurements of ascorbate and glutamate in vivo in the rat brain using carbon fiber nanocomposite sensors and microbiosensor arrays. Bioelectrochemistry (Amsterdam, Netherlands). vol 121. 2018-05-01. PMID:29413864. |
the estimated average basal concentration of ascorbate in vivo in the ca1, ca3 and dentate gyrus (dg) sub regions of the hippocampus were 276±60μm (n=10), 183±30μm (n=10) and 133±42μm (n=10), respectively. |
2018-05-01 |
2023-08-13 |
rat |
| Wei Yao, Ji-Chun Zhang, Tamaki Ishima, Chao Dong, Chun Yang, Qian Ren, Min Ma, Mei Han, Jin Wu, Hiroyuki Suganuma, Yusuke Ushida, Masayuki Yamamoto, Kenji Hashimot. Role of Keap1-Nrf2 signaling in depression and dietary intake of glucoraphanin confers stress resilience in mice. Scientific reports. vol 6. 2018-04-30. PMID:27470577. |
we found lower expression of keap1 and nrf2 proteins in the prefrontal cortex (pfc), ca3 and dentate gyrus (dg) of hippocampus in mice with depression-like phenotype compared to control mice. |
2018-04-30 |
2023-08-13 |
mouse |
| Fariba Baei, Aliakbar Rajabzadeh, Javad Bagheri, Zahra Jalayeri, Alireza Ebrahimzadeh-Bideska. Effect of methamphetamine exposure during pregnancy and lactation on polysialic acid-neural cell adhesion molecule expression in rat's offspring hippocampus. Metabolic brain disease. vol 32. issue 4. 2018-04-23. PMID:28243847. |
in one-day infant rats with ma exposure during pregnancy, a significant decrease was observed in the number of psa-ncam positive cells in the ca1 (p = 0.047), ca3 (p = 0.05) and dg (p = 0.006) hippocampus regions compared to control and expression intensity of these molecules in all the three regions (p ≤ 0.05). |
2018-04-23 |
2023-08-13 |
rat |
| Shauna M Stark, Craig E L Star. Age-related deficits in the mnemonic similarity task for objects and scenes. Behavioural brain research. vol 333. 2018-04-20. PMID:28673769. |
in particular, lure discrimination performance for objects showed a positive relationship with the volume of the hippocampus, specifically the combined dentate gyrus (dg) and ca3 subfields, and the subiculum. |
2018-04-20 |
2023-08-13 |
Not clear |
| Xiao-Yu Zheng, Qian-Quan Wan, Chuan-Yi Zheng, Hong-Long Zhou, Xing-Yu Dong, Qing-Shan Deng, Hui Yao, Qiang Fu, Mou Gao, Zhong-Jie Yan, Shan-Shan Wang, Yu You, Jun Lv, Xiang-Yu Wang, Ke-En Chen, Mao-Ying Zhang, Ru-Xiang X. Amniotic Mesenchymal Stem Cells Decrease Aβ Deposition and Improve Memory in APP/PS1 Transgenic Mice. Neurochemical research. vol 42. issue 8. 2018-04-19. PMID:28397068. |
furthermore, enhanced hippocampal neurogenesis in the subgranular zone (sgz) of the dentate gyrus (dg) and enhanced synaptic plasticity following ham-msc treatment could be another important factor in reversing the cognitive decline in app/ps1 mice. |
2018-04-19 |
2023-08-13 |
mouse |
| Olga Krupska, Anna Sarnowska, Bartlomiej Fedorczyk, Magdalena Gewartowska, Aleksandra Misicka, Barbara Zablocka, Malgorzata Beresewic. Ischemia/Reperfusion-Induced Translocation of PKCβII to Mitochondria as an Important Mediator of a Protective Signaling Mechanism in an Ischemia-Resistant Region of the Hippocampus. Neurochemical research. vol 42. issue 8. 2018-04-19. PMID:28401402. |
as we have demonstrated previously ischemia/reperfusion injury (i/r) results in translocation of pkcβ from cytoplasm to mitochondria, but only in ischemia-resistant regions of the hippocampus (ca2-4, dg), we hypothesize that this translocation may be a mediator of a protective signaling mechanism in this region. |
2018-04-19 |
2023-08-13 |
Not clear |
| Ignazio S Piras, Jonida Krate, Isabelle Schrauwen, Jason J Corneveaux, Geidy E Serrano, Lucia Sue, Thomas G Beach, Matthew J Huentelma. Whole transcriptome profiling of the human hippocampus suggests an involvement of the KIBRA rs17070145 polymorphism in differential activation of the MAPK signaling pathway. Hippocampus. vol 27. issue 7. 2018-04-18. PMID:28380666. |
to achieve a better understanding of the pathways modulated by rs17070145 and its associated functional variant(s), we used laser capture microdissection (lcm) and rna-sequencing to investigate the effect of rs17070145 genotypes on whole transcriptome expression in the human hippocampus (hp) of 22 neuropathologically normal individuals, with a specific focus on the dentate gyrus (dg) and at the pyramidal cells (pc) of ca1 and ca3 sub-regions. |
2018-04-18 |
2023-08-13 |
human |
| Jillian N Moretto, Áine M Duffy, Helen E Scharfma. Acute restraint stress decreases c-fos immunoreactivity in hilar mossy cells of the adult dentate gyrus. Brain structure & function. vol 222. issue 5. 2018-04-17. PMID:28190104. |
in prior work, it was identified that control rats that were perfusion-fixed after removal from their home cage exhibited c-fos immunoreactivity (ir) in the dg in a spatially stereotyped pattern: ventral mcs and dorsal granule cells (gcs) expressed c-fos protein (duffy et al., hippocampus 23:649-655, 2013). |
2018-04-17 |
2023-08-13 |
rat |
| Fábio G Teixeira, Krishna M Panchalingam, Rita Assunção-Silva, Sofia C Serra, Bárbara Mendes-Pinheiro, Patrícia Patrício, Sunghoon Jung, Sandra I Anjo, Bruno Manadas, Luísa Pinto, Nuno Sousa, Leo A Behie, António J Salgad. Modulation of the Mesenchymal Stem Cell Secretome Using Computer-Controlled Bioreactors: Impact on Neuronal Cell Proliferation, Survival and Differentiation. Scientific reports. vol 6. 2018-04-16. PMID:27301770. |
a similar trend was also observed in the hippocampal dentate gyrus (dg) of rat brains where, upon injection, an enhanced neuronal and astrocytic survival and differentiation, was observed. |
2018-04-16 |
2023-08-13 |
human |
| Ian Mahar, Angus MacIsaac, John Junghan Kim, Calvin Qiang, Maria Antonietta Davoli, Gustavo Turecki, Naguib Mechawa. Effects of neuregulin-1 administration on neurogenesis in the adult mouse hippocampus, and characterization of immature neurons along the septotemporal axis. Scientific reports. vol 6. 2018-04-16. PMID:27469430. |
these results indicate neurogenic involvement of nrg1-induced antidepressant-like behaviour is particularly associated with increased ventral dg cell proliferation, and identify novel distinctions between dorsal and ventral hippocampal neurogenic development. |
2018-04-16 |
2023-08-13 |
mouse |