| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fan Hu, Meng-Meng Ge, Wei-Heng Che. Effects of lead exposure on dendrite and spine development in hippocampal dentate gyrus areas of rats. Synapse (New York, N.Y.). vol 70. issue 3. 2016-10-17. PMID:26562488. |
lead exposure has been implicated in the impairment of synaptic plasticity in the hippocampal dentate gyrus (dg) areas of rats. |
2016-10-17 |
2023-08-13 |
rat |
| Fan Hu, Meng-Meng Ge, Wei-Heng Che. Effects of lead exposure on dendrite and spine development in hippocampal dentate gyrus areas of rats. Synapse (New York, N.Y.). vol 70. issue 3. 2016-10-17. PMID:26562488. |
our results indicated that, for both ages, lead exposure significantly decreased the total dendritic length and spine density of granule neurons in the dg of the rat hippocampus. |
2016-10-17 |
2023-08-13 |
rat |
| Fan Hu, Meng-Meng Ge, Wei-Heng Che. Effects of lead exposure on dendrite and spine development in hippocampal dentate gyrus areas of rats. Synapse (New York, N.Y.). vol 70. issue 3. 2016-10-17. PMID:26562488. |
our present findings are the first to show that developmental lead exposure disturbs branch and spine formation in hippocampal dg areas. |
2016-10-17 |
2023-08-13 |
rat |
| S Monteiro, F M Ferreira, V Pinto, S Roque, M Morais, D de Sá-Calçada, C Mota, M Correia-Neves, J J Cerqueir. Absence of IFNγ promotes hippocampal plasticity and enhances cognitive performance. Translational psychiatry. vol 6. 2016-10-17. PMID:26731444. |
in the dorsal hippocampus, the absence of this pro-inflammatory cytokine leads to an increase in the numbers of newly born neurons in the subgranular zone of the dentate gyrus (dg), an adult neurogenic niche known to support learning and memory, and to an enlargement of the dendritic arborization of dg granule and cornu ammonis (ca)1 pyramidal neurons. |
2016-10-17 |
2023-08-13 |
Not clear |
| Joshua Sariñana, Susumu Tonegaw. Differentiation of forebrain and hippocampal dopamine 1-class receptors, D1R and D5R, in spatial learning and memory. Hippocampus. vol 26. issue 1. 2016-10-13. PMID:26174222. |
d1r- and d5r-specific in situ hybridization probes showed that forebrain restricted d1r and d5r ko mice (f-d1r/d5r ko) displayed d1r mrna deletion in the medial (m)pfc, dorsal and ventral striatum, and the dentate gyrus (dg) of the hippocampus. |
2016-10-13 |
2023-08-13 |
mouse |
| Joshua Sariñana, Susumu Tonegaw. Differentiation of forebrain and hippocampal dopamine 1-class receptors, D1R and D5R, in spatial learning and memory. Hippocampus. vol 26. issue 1. 2016-10-13. PMID:26174222. |
d5r mrna deletion was limited to the mpfc, the ca1 and dg hippocampal subregions. |
2016-10-13 |
2023-08-13 |
mouse |
| Ana M Daugherty, Andrew R Bender, Naftali Raz, Noa Ofe. Age differences in hippocampal subfield volumes from childhood to late adulthood. Hippocampus. vol 26. issue 2. 2016-10-13. PMID:26286891. |
the hippocampus is composed of distinct subfields: the four cornu ammonis areas (ca1-ca4), dentate gyrus (dg), and subiculum. |
2016-10-13 |
2023-08-13 |
human |
| Ibrahim A Alhaider, Karim A Alkadh. Caffeine treatment prevents rapid eye movement sleep deprivation-induced impairment of late-phase long-term potentiation in the dentate gyrus. The European journal of neuroscience. vol 42. issue 10. 2016-10-13. PMID:26449851. |
the ca1 and dentate gyrus (dg) are physically and functionally closely related areas of the hippocampus, but they differ in various respects, including their reactions to different insults. |
2016-10-13 |
2023-08-13 |
rat |
| Ibrahim A Alhaider, Karim A Alkadh. Caffeine treatment prevents rapid eye movement sleep deprivation-induced impairment of late-phase long-term potentiation in the dentate gyrus. The European journal of neuroscience. vol 42. issue 10. 2016-10-13. PMID:26449851. |
the purpose of this study was to determine the protective effects of chronic caffeine treatment on late-phase long-term potentiation (l-ltp) and its signalling cascade in the dg area of the hippocampus of rapid eye movement sleep-deprived rats. |
2016-10-13 |
2023-08-13 |
rat |
| Sha Sha, Jin Xu, Zi-Hong Lu, Juan Hong, Wei-Jun Qu, Jian-Wei Zhou, Ling Che. Lack of JWA Enhances Neurogenesis and Long-Term Potentiation in Hippocampal Dentate Gyrus Leading to Spatial Cognitive Potentiation. Molecular neurobiology. vol 53. issue 1. 2016-10-10. PMID:25432888. |
we generated systemic and neuronal jwa knockout (jwa-ko and jwa-nko) mice to investigate the influence of jwa deficiency on spatial cognitive performance, process of neurogenesis, and induction of long-term potentiation (ltp) in hippocampal dentate gyrus (dg). |
2016-10-10 |
2023-08-13 |
mouse |
| Sha Sha, Jin Xu, Zi-Hong Lu, Juan Hong, Wei-Jun Qu, Jian-Wei Zhou, Ling Che. Lack of JWA Enhances Neurogenesis and Long-Term Potentiation in Hippocampal Dentate Gyrus Leading to Spatial Cognitive Potentiation. Molecular neurobiology. vol 53. issue 1. 2016-10-10. PMID:25432888. |
in hippocampal dg of jwa-nko mice, either survival and migration or neurite growth of newborn neurons were significantly enhanced without the changes in proliferation and differentiation of stem cells. |
2016-10-10 |
2023-08-13 |
mouse |
| Sha Sha, Jin Xu, Zi-Hong Lu, Juan Hong, Wei-Jun Qu, Jian-Wei Zhou, Ling Che. Lack of JWA Enhances Neurogenesis and Long-Term Potentiation in Hippocampal Dentate Gyrus Leading to Spatial Cognitive Potentiation. Molecular neurobiology. vol 53. issue 1. 2016-10-10. PMID:25432888. |
the results suggest that the jwa deficiency through cascading fak-pi3k-akt-mtor pathway increases the newborn neurons and enhances the ltp induction in hippocampal dg, which leads to the spatial cognitive potentiation. |
2016-10-10 |
2023-08-13 |
mouse |
| Jonathan K Y Lai, Laurie C Doering, Jane A Foste. Developmental expression of the neuroligins and neurexins in fragile X mice. The Journal of comparative neurology. vol 524. issue 4. 2016-10-07. PMID:26235839. |
genotype-based differences in expression included increased nlgn1 mrna in ca1 and s1 cortex, decreased nlgn2 mrna in ca1 and dentate gyrus (dg) regions of the hippocampus, and increased nrxn3 mrna in ca1, dg, and s1 cortex between female wt and fmr1-ko mice. |
2016-10-07 |
2023-08-13 |
mouse |
| Robert F Hevne. Evolution of the mammalian dentate gyrus. The Journal of comparative neurology. vol 524. issue 3. 2016-10-06. PMID:26179319. |
compared with homologous areas in sauropsids (birds and reptiles), the mammalian dg is larger and exhibits qualitatively different phenotypes: 1) folded (c- or v-shaped) granule neuron layer, concave toward the hilus and delimited by a hippocampal fissure; 2) nonperiventricular adult neurogenesis; and 3) prolonged ontogeny, involving extensive abventricular (basal) migration and proliferation of neural stem and progenitor cells (nspcs). |
2016-10-06 |
2023-08-13 |
Not clear |
| Robert F Hevne. Evolution of the mammalian dentate gyrus. The Journal of comparative neurology. vol 524. issue 3. 2016-10-06. PMID:26179319. |
parsimony suggests that increased growth and convolution of the dg arose in stem mammals concurrently with nonperiventricular adult hippocampal neurogenesis and basal migration of nspcs during development. |
2016-10-06 |
2023-08-13 |
Not clear |
| Rina Zilkha-Falb, Nathali Kaushansky, Naoto Kawakami, Avraham Ben-Nu. Post-CNS-inflammation expression of CXCL12 promotes the endogenous myelin/neuronal repair capacity following spontaneous recovery from multiple sclerosis-like disease. Journal of neuroinflammation. vol 13. 2016-10-06. PMID:26747276. |
we investigated the expression dynamics of cxcl12 in the cns with progression of clinical eae and following spontaneous recovery, with a focus on cxcl12 expression in the hippocampal neurogenic dentate gyrus (dg) and in the corpus callosum (cc) of spontaneously recovered mice, and its potential role in promoting the endogenous myelin/neuronal repair capacity. |
2016-10-06 |
2023-08-13 |
mouse |
| Yukihiko Shirayama, Chun Yang, Ji-chun Zhang, Qian Ren, Wei Yao, Kenji Hashimot. Alterations in brain-derived neurotrophic factor (BDNF) and its precursor proBDNF in the brain regions of a learned helplessness rat model and the antidepressant effects of a TrkB agonist and antagonist. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 12. 2016-10-05. PMID:26419294. |
lh rats showed a reduction of bdnf in the medial prefrontal cortex (mpfc), ca3, and dentate gyrus (dg) of the hippocampus, whereas lh rats showed an increase in bdnf in the nucleus accumbens (nac). |
2016-10-05 |
2023-08-13 |
rat |
| Jiaqi Chu, Yalin Tu, Jingkao Chen, Dunxian Tan, Xingguo Liu, Rongbiao P. Effects of melatonin and its analogues on neural stem cells. Molecular and cellular endocrinology. vol 420. 2016-09-30. PMID:26499395. |
nscs are found in two main regions in the adult brain: the subgranular zone (sgz) in the hippocampal dentate gyrus (dg) and the subventricular zone (svz). |
2016-09-30 |
2023-08-13 |
Not clear |
| Masoumeh Nazari, Alireza Komaki, Ruhollah Karamian, Siamak Shahidi, Abdolrahman Sarihi, Masoumeh Asadbeg. The interactive role of CB(1) and GABA(B) receptors in hippocampal synaptic plasticity in rats. Brain research bulletin. vol 120. 2016-09-30. PMID:26611204. |
in this study, we examined the hippocampal effects of co-administrating am251 and cgp55845, which are cb1 and gabab antagonists, respectively, on ltp induction in the dentate gyrus (dg) of rats. |
2016-09-30 |
2023-08-13 |
rat |
| Yoshihiro Kobayashi, Tetsushi Hirano, Takuya Omotehara, Rie Hashimoto, Yuria Umemura, Hideto Yuasa, Natsumi Masuda, Naoto Kubota, Kiichi Minami, Shogo Yanai, Mitsuko Ishihara-Sugano, Youhei Mantani, Toshifumi Yokoyama, Hiroshi Kitagawa, Nobuhiko Hosh. Immunohistochemical analysis of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) toxicity on the developmental dentate gyrus and hippocampal fimbria in fetal mice. The Journal of veterinary medical science. vol 77. issue 11. 2016-09-28. PMID:26096965. |
together, these results demonstrate that maternal tcdd exposure has adverse impacts on neural stem cells (nscs), neural precursor cells (npcs) and granular cells in the dg and disrupts the nsc maintenance and timing of differentiation in the hippocampal fimbria, which in turn interrupt neuronal development in future generations of mice. |
2016-09-28 |
2023-08-13 |
mouse |