| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Raffaella Alò, Maria Mele, Gilda Fazzari, Ennio Avolio, Marcello Canonac. Exposure to sub-chronic unpredictable stress accounts for antidepressant-like effects in hamsters treated with BDNF and CNQX. Brain research bulletin. vol 118. 2016-08-22. PMID:26409118. |
sub-chronic administration of bdnf in the hippocampal dentate gyrus (dg) of stressed hamsters was responsible for very evident (p<0.001) sucrose consumption along with notably elevated swimming bouts and reduced immobility states in the forced swim test (fst). |
2016-08-22 |
2023-08-13 |
Not clear |
| E Anne Martin, Shruti Muralidhar, Zhirong Wang, Diégo Cordero Cervantes, Raunak Basu, Matthew R Taylor, Jennifer Hunter, Tyler Cutforth, Scott A Wilke, Anirvan Ghosh, Megan E William. The intellectual disability gene Kirrel3 regulates target-specific mossy fiber synapse development in the hippocampus. eLife. vol 4. 2016-08-22. PMID:26575286. |
in this study, we demonstrate kirrel3 regulates target-specific synapse formation at hippocampal mossy fiber (mf) synapses, which connect dentate granule (dg) neurons to both ca3 and gabaergic neurons. |
2016-08-22 |
2023-08-13 |
mouse |
| M Dolores Muñoz, Mónica Antolín-Vallespín, Silvia Tapia-González, Amelia Sánchez-Capel. Smad3 deficiency inhibits dentate gyrus LTP by enhancing GABAA neurotransmission. Journal of neurochemistry. vol 137. issue 2. 2016-08-22. PMID:26826552. |
the long-term potentiation (ltp) induced in the dg by high-frequency stimulation of the medial perforant pathway is abolished in the dg of smad3-deficient mice, but not in the ca1 hippocampal region. |
2016-08-22 |
2023-08-13 |
mouse |
| M Dolores Muñoz, Mónica Antolín-Vallespín, Silvia Tapia-González, Amelia Sánchez-Capel. Smad3 deficiency inhibits dentate gyrus LTP by enhancing GABAA neurotransmission. Journal of neurochemistry. vol 137. issue 2. 2016-08-22. PMID:26826552. |
hence, smad3 signaling in the dg appears to be necessary to induce ltp by regulating gabaa neurotransmission, suggesting a central role of this intracellular signaling pathway in the hippocampal brain plasticity related to learning and memory. |
2016-08-22 |
2023-08-13 |
mouse |
| Junhong Zhao, Minghong Sui, Xiao Lü, Dongmei Jin, Zhiqiang Zhuang, Tiebin Ya. Electroacupuncture promotes neural stem cell proliferation and neurogenesis in the dentate gyrus of rats following stroke via upregulation of Notch1 expression. Molecular medicine reports. vol 12. issue 5. 2016-08-15. PMID:26328605. |
reverse transcription quantitative polymerase chain reaction (rt‑qpcr) and western blot analyses were performed to detect the expression levels of notch1 and hes1 in the dentate gyrus (dg) of the hippocampus of rats following mcao. |
2016-08-15 |
2023-08-13 |
rat |
| Juri-Alexander Witt, Roland Coras, Johannes Schramm, Albert J Becker, Christian E Elger, Ingmar Blümcke, Christoph Helmstaedte. Relevance of hippocampal integrity for memory outcome after surgical treatment of mesial temporal lobe epilepsy. Journal of neurology. vol 262. issue 10. 2016-08-09. PMID:26138541. |
in 104 patients who had undergone epilepsy surgery for unilateral mtle, we analyzed pre- to postoperative changes of verbal and figural memory as a function of segmental neuronal cell densities of the resected hippocampus (cornu ammonis, ca1-4; internal and external limb of the dentate gyrus, dg). |
2016-08-09 |
2023-08-13 |
Not clear |
| Maria A Rocca, Giulia Longoni, Elisabetta Pagani, Giacomo Boffa, Bruno Colombo, Mariaemma Rodegher, Gianvito Martino, Andrea Falini, Giancarlo Comi, Massimo Filipp. In vivo evidence of hippocampal dentate gyrus expansion in multiple sclerosis. Human brain mapping. vol 36. issue 11. 2016-08-09. PMID:26287572. |
using mr-based radial mapping, we assessed morphological alterations of the hippocampal dentate gyrus (dg) in patients with relapse-onset multiple sclerosis (ms). |
2016-08-09 |
2023-08-13 |
Not clear |
| Maria A Rocca, Giulia Longoni, Elisabetta Pagani, Giacomo Boffa, Bruno Colombo, Mariaemma Rodegher, Gianvito Martino, Andrea Falini, Giancarlo Comi, Massimo Filipp. In vivo evidence of hippocampal dentate gyrus expansion in multiple sclerosis. Human brain mapping. vol 36. issue 11. 2016-08-09. PMID:26287572. |
between-groups differences of dg radial distance (from surface points to the central core of the hippocampus) and correlations with clinical, neuropsychological, and radiological measures were evaluated using surface-based mesh modeling. |
2016-08-09 |
2023-08-13 |
Not clear |
| Maria A Rocca, Giulia Longoni, Elisabetta Pagani, Giacomo Boffa, Bruno Colombo, Mariaemma Rodegher, Gianvito Martino, Andrea Falini, Giancarlo Comi, Massimo Filipp. In vivo evidence of hippocampal dentate gyrus expansion in multiple sclerosis. Human brain mapping. vol 36. issue 11. 2016-08-09. PMID:26287572. |
surface expansion of the dg might represent an inflammation-induced neurogenic (reactive) process of the subgranular zone of the hippocampus primarily aimed at rescuing the functional competence of hippocampal circuitry. |
2016-08-09 |
2023-08-13 |
Not clear |
| An T Dao, Munder A Zagaar, Karim A Alkadh. Moderate Treadmill Exercise Protects Synaptic Plasticity of the Dentate Gyrus and Related Signaling Cascade in a Rat Model of Alzheimer's Disease. Molecular neurobiology. vol 52. issue 3. 2016-08-08. PMID:25288155. |
the dentate gyrus (dg) of the hippocampus is known to be more resistant to the effects of various external factors than other hippocampal areas. |
2016-08-08 |
2023-08-13 |
rat |
| Shigeki Moriguchi, Hiroyuki Sakagami, Yasushi Yabuki, Yuzuru Sasaki, Hisanao Izumi, Chen Zhang, Feng Han, Kohji Fukunag. Stimulation of Sigma-1 Receptor Ameliorates Depressive-like Behaviors in CaMKIV Null Mice. Molecular neurobiology. vol 52. issue 3. 2016-08-08. PMID:25316382. |
calcium/calmodulin-dependent protein kinase iv (camkiv) null mice exhibit depressive-like behaviors and impaired neurogenesis as assessed by bromodeoxyuridine (brdu) incorporation into newborn cells of the hippocampal dentate gyrus (dg). |
2016-08-08 |
2023-08-13 |
mouse |
| Shigeki Moriguchi, Hiroyuki Sakagami, Yasushi Yabuki, Yuzuru Sasaki, Hisanao Izumi, Chen Zhang, Feng Han, Kohji Fukunag. Stimulation of Sigma-1 Receptor Ameliorates Depressive-like Behaviors in CaMKIV Null Mice. Molecular neurobiology. vol 52. issue 3. 2016-08-08. PMID:25316382. |
such stimulation also improved hippocampal long-term potentiation (ltp) induction and maintenance, which are impaired in the dg of camkiv null mice. |
2016-08-08 |
2023-08-13 |
mouse |
| Hong Liu, Xinhong Xue, Huijian Shi, Lifeng Qi, Dianrong Gon. Osthole Upregulates BDNF to Enhance Adult Hippocampal Neurogenesis in APP/PS1 Transgenic Mice. Biological & pharmaceutical bulletin. vol 38. issue 10. 2016-07-25. PMID:26424009. |
adult hippocampal neurogenesis occurs in the dentate gyrus (dg) of the mouse hippocampus, and plays roles in learning and memory progresses. |
2016-07-25 |
2023-08-13 |
mouse |
| Hong Liu, Xinhong Xue, Huijian Shi, Lifeng Qi, Dianrong Gon. Osthole Upregulates BDNF to Enhance Adult Hippocampal Neurogenesis in APP/PS1 Transgenic Mice. Biological & pharmaceutical bulletin. vol 38. issue 10. 2016-07-25. PMID:26424009. |
once daily) treatment dramatically ameliorated the cognitive impairments by morris water maze test and passive avoidance test, and augmented neurogenesis in the dg of hippocampus in app/ps1 mice. |
2016-07-25 |
2023-08-13 |
mouse |
| Abdeslam Mouihat. Prenatal Activation of Toll-Like Receptor-4 Dampens Adult Hippocampal Neurogenesis in An IL-6 Dependent Manner. Frontiers in cellular neuroscience. vol 10. 2016-07-22. PMID:27445700. |
the newly born neurons were monitored in the subventricular zone (svz) and the dentate gyrus (dg) of the hippocampus of adult male offspring by monitoring doublecortin and t-box brain protein-2 expression: two well-established markers of newly born neurons. |
2016-07-22 |
2023-08-13 |
rat |
| C P Hutton, N Déry, E Rosa, J A Lemon, C D Rollo, D R Boreham, M Fahnestock, D deCatanzaro, J M Wojtowicz, S Becke. Synergistic effects of diet and exercise on hippocampal function in chronically stressed mice. Neuroscience. vol 308. 2016-07-19. PMID:26358368. |
the combination of dietary supplementation and exercise had multiple beneficial effects, as reflected in the number of doublecortin (dcx)-positive immature neurons in the dentate gyrus (dg), the sectional area of the dg and hippocampal ca1, as well as increased hippocampal bdnf messenger ribonucleic acid (mrna) and serum vascular endothelial growth factor (vegf) levels. |
2016-07-19 |
2023-08-13 |
mouse |
| Adva Sharvit, Menahem Segal, Orli Kehat, Oliver Stork, Gal Richter-Levi. Differential modulation of synaptic plasticity and local circuit activity in the dentate gyrus and CA1 regions of the rat hippocampus by corticosterone. Stress (Amsterdam, Netherlands). vol 18. issue 3. 2016-07-13. PMID:25815975. |
we have now examined the effects of corticosterone (cort) on extrinsic afferent and local circuit plasticity of the perforant path on the dentate gyrus (dg) and the ventral hippocampal commissure on ca1. |
2016-07-13 |
2023-08-13 |
rat |
| Mari Kojima, Hiroaki Takehara, Takanori Akagi, Hirofumi Shiono, Takanori Ichik. Flexible Sheet-Type Sensor for Noninvasive Measurement of Cellular Oxygen Metabolism on a Culture Dish. PloS one. vol 10. issue 12. 2016-07-06. PMID:26624889. |
furthermore, to demonstrate the utility of the developed sensing system, we demonstrated the mapping of the oxygen consumption rate of rat brain slices and succeeded in visualizing a clear difference among the layer structures of the hippocampus, i.e., the cornu ammonis (ca1 and ca3) and dentate gyrus (dg). |
2016-07-06 |
2023-08-13 |
human |
| Michael G Ruscio, S Bradley King, Harold L Hau. Social isolation increases cell proliferation in male and cell survival in female California mice (Peromyscus californicus). Physiology & behavior. vol 151. 2016-06-28. PMID:26342752. |
after 4 days, isolated males had greater cellular proliferation in the dentate gyrus of the hippocampus (dg) than pair housed males. |
2016-06-28 |
2023-08-13 |
mouse |
| Jens Stepan, Florian Hladky, Andrés Uribe, Florian Holsboer, Mathias V Schmidt, Matthias Ede. High-Speed imaging reveals opposing effects of chronic stress and antidepressants on neuronal activity propagation through the hippocampal trisynaptic circuit. Frontiers in neural circuits. vol 9. 2016-06-21. PMID:26594153. |
here, enabled by a recently developed voltage-sensitive dye imaging (vsdi) assay in mouse brain slices, we examined the impact of chronic stress and concentration-dependent effects of eight clinically used ads (belonging to different chemical/functional classes) on evoked neuronal activity propagations through the hippocampal trisynaptic circuitry (htc: perforant path → dentate gyrus (dg) → area ca3 → area ca1). |
2016-06-21 |
2023-08-13 |
mouse |