Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Miranda C Staples, Airee Kim, Chitra D Mandya. Dendritic remodeling of hippocampal neurons is associated with altered NMDA receptor expression in alcohol dependent rats. Molecular and cellular neurosciences. vol 65. 2016-01-11. PMID:25769285. |
for this study, we investigated seven weeks of cie-induced morphological changes (dendritic complexity and dendritic spine density) of dentate gyrus (dg) granule cell neurons, ca3, and ca1 pyramidal neurons and the associated alterations in biochemical markers of synaptic plasticity and toxicity (nmda receptors and psd-95) in the hippocampus in ethanol-experienced wistar rats 3h (cie) and 21days (protracted abstinence) after the last ethanol vapor exposure. |
2016-01-11 |
2023-08-13 |
rat |
Fábio G Teixeira, Miguel M Carvalho, Andreia Neves-Carvalho, Krishna M Panchalingam, Leo A Behie, Luísa Pinto, Nuno Sousa, António J Salgad. Secretome of mesenchymal progenitors from the umbilical cord acts as modulator of neural/glial proliferation and differentiation. Stem cell reviews and reports. vol 11. issue 2. 2016-01-08. PMID:25420577. |
in the present work, we aimed to assess if the secretome of hucpvcs is able to 1) induce the differentiation of human telencephalon neural precursor cells (htnpcs) in vitro, and 2) modulate neural/glial proliferation, differentiation and survival in the dentate gyrus (dg) of adult rat hippocampus. |
2016-01-08 |
2023-08-13 |
human |
Ming-Shian Tsai, Meng-Larn Lee, Chun-Yun Chang, Hsiang-Hsuan Fan, I-Shing Yu, You-Tzung Chen, Jhih-Yi You, Chun-Yu Chen, Fang-Chia Chang, Jane H Hsiao, Olga Khorkova, Horng-Huei Liou, Yuchio Yanagawa, Li-Jen Lee, Shu-Wha Li. Functional and structural deficits of the dentate gyrus network coincide with emerging spontaneous seizures in an Scn1a mutant Dravet Syndrome model during development. Neurobiology of disease. vol 77. 2016-01-06. PMID:25725421. |
the nature and timing of changes caused by scn1a mutation in the hippocampal dentate gyrus (dg) network, a core area for gating major excitatory input to hippocampus and a classic epileptogenic zone, are not well known. |
2016-01-06 |
2023-08-13 |
mouse |
Ming-Shian Tsai, Meng-Larn Lee, Chun-Yun Chang, Hsiang-Hsuan Fan, I-Shing Yu, You-Tzung Chen, Jhih-Yi You, Chun-Yu Chen, Fang-Chia Chang, Jane H Hsiao, Olga Khorkova, Horng-Huei Liou, Yuchio Yanagawa, Li-Jen Lee, Shu-Wha Li. Functional and structural deficits of the dentate gyrus network coincide with emerging spontaneous seizures in an Scn1a mutant Dravet Syndrome model during development. Neurobiology of disease. vol 77. 2016-01-06. PMID:25725421. |
during the same period, the het dg exhibited a greater reduction of nav1.1-expressing gabaergic neurons compared to other hippocampal areas. |
2016-01-06 |
2023-08-13 |
mouse |
Zhen Zhang, Feng Gao, Xiaokui Kang, Jia Li, Litong Zhang, Wentao Dong, Zhangning Jin, Fan Li, Nannan Gao, Xinwang Cai, Shuyuan Yang, Jianning Zhang, Xinliang Ren, Xinyu Yan. Exploring the potential relationship between Notch pathway genes expression and their promoter methylation in mice hippocampal neurogenesis. Brain research bulletin. vol 113. 2016-01-04. PMID:25701255. |
we observed the expression of notch1, hes1 and ngn2 in hippocampal dg with qpcr, western blot and immunofluorescence staining. |
2016-01-04 |
2023-08-13 |
mouse |
Zhen Zhang, Feng Gao, Xiaokui Kang, Jia Li, Litong Zhang, Wentao Dong, Zhangning Jin, Fan Li, Nannan Gao, Xinwang Cai, Shuyuan Yang, Jianning Zhang, Xinliang Ren, Xinyu Yan. Exploring the potential relationship between Notch pathway genes expression and their promoter methylation in mice hippocampal neurogenesis. Brain research bulletin. vol 113. 2016-01-04. PMID:25701255. |
the number of notch1 or hes1 (+) and brdu (+) cells decreased in the subgranular zone (sgz) of the dg in the hippocampus following tbi. |
2016-01-04 |
2023-08-13 |
mouse |
Kazuhisa Tanaka, Atushi Shoji, Masao Sugawar. An enzyme-entrapped agarose gel for visualization of ischemia-induced L-glutamate fluxes in hippocampal slices in a flow system. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry. vol 31. issue 4. 2016-01-04. PMID:25864676. |
monitoring the time-dependent change of ischemia-induced l-glutamate fluxes at neuronal regions ca1, dg and ca3 of hippocampal slices is demonstrated. |
2016-01-04 |
2023-08-13 |
Not clear |
Takashi Kitamura, Chen Sun, Jared Martin, Lacey J Kitch, Mark J Schnitzer, Susumu Tonegaw. Entorhinal Cortical Ocean Cells Encode Specific Contexts and Drive Context-Specific Fear Memory. Neuron. vol 87. issue 6. 2015-12-30. PMID:26402611. |
the hippocampal dentate gyrus (dg) and ca3 are known to contribute to these functions, but the role of the entorhinal cortex (ec) is poorly understood. |
2015-12-30 |
2023-08-13 |
Not clear |
Catrinel Girbovan, Hélène Plamondo. Resveratrol downregulates type-1 glutamate transporter expression and microglia activation in the hippocampus following cerebral ischemia reperfusion in rats. Brain research. vol 1608. 2015-12-24. PMID:25727173. |
on microglia and astrocyte activation and characterized glt-1 expression in the dentate gyrus (dg), ca1 and ca3 layers of the hippocampus 7 days following 10min global ischemia. |
2015-12-24 |
2023-08-13 |
rat |
Wen Zong, Shuoyang Liu, Xiaotong Wang, Jian Zhang, Tingting Zhang, Ziyi Liu, Dongdong Wang, Aizhen Zhang, Minsheng Zhu, Jiangang Ga. Trio gene is required for mouse learning ability. Brain research. vol 1608. 2015-12-24. PMID:25727174. |
trio gene deletion results in smaller brains, an abnormal hippocampus and disordered granule cells in the dentate gyrus (dg) and cornu ammonis (ca). |
2015-12-24 |
2023-08-13 |
mouse |
Hermes Pofantis, Panagiotis Georgopoulos, Theodoros Petrides, Costas Papatheodoropoulo. Differences in paired-pulse inhibition and facilitation in the dentate gyrus and CA3 field between dorsal and ventral rat hippocampus. Brain research. vol 1608. 2015-12-24. PMID:25770056. |
we studied the processes of inhibition and facilitation in the dentate gyrus (dg) and the ca3 field by examining the effects of paired-pulse stimulation on the evoked population spike (ps) in dorsal (dh) and ventral (vh) hippocampal slices from the adult rat. |
2015-12-24 |
2023-08-13 |
rat |
N Arias, M Méndez, J L Aria. Differential contribution of the hippocampus in two different demanding tasks at early stages of hepatic encephalopathy. Neuroscience. vol 284. 2015-12-22. PMID:25290018. |
to label brain areas related to these tasks, we marked the expression of the c-fos protein and revealed high c-fos immunoreactivity in cornu ammonis 1 (ca1), cornu ammonis 3 (ca3) and entorhinal (ent) cortex of the ph group compared with the sham group in the object-place recognition task and a decrease in c-fos-positive cells in the reversal task in the ca1, ca3, dentate gyrus (dg), cingulate (cg), prelimbic (pl), and infralimbic (il) cortices in the ph group compared with the sham group. |
2015-12-22 |
2023-08-13 |
Not clear |
D H Kim, H E Lee, K J Kwon, S J Park, H Heo, Y Lee, J W Choi, C Y Shin, J H Ry. Early immature neuronal death initiates cerebral ischemia-induced neurogenesis in the dentate gyrus. Neuroscience. vol 284. 2015-12-22. PMID:25301746. |
throughout adulthood, neurons are continuously replaced by new cells in the dentate gyrus (dg) of the hippocampus, and this neurogenesis is increased by various neuronal injuries including ischemic stroke and seizure. |
2015-12-22 |
2023-08-13 |
mouse |
D H Kim, H E Lee, K J Kwon, S J Park, H Heo, Y Lee, J W Choi, C Y Shin, J H Ry. Early immature neuronal death initiates cerebral ischemia-induced neurogenesis in the dentate gyrus. Neuroscience. vol 284. 2015-12-22. PMID:25301746. |
here, we investigated which signal(s) trigger(s) ischemia-induced cell proliferation and neurogenesis in the hippocampal dg region. |
2015-12-22 |
2023-08-13 |
mouse |
Franco Ortiz, Rafael Gutiérre. Entorhinal cortex lesions result in adenosine-sensitive high frequency oscillations in the hippocampus. Experimental neurology. vol 271. 2015-12-22. PMID:26072121. |
entorhinal cortex (ec) projections to the hippocampus run along the perforant path and activate the hippocampal area ca3 and the dentate gyrus (dg), which, in turn, drives ca3. |
2015-12-22 |
2023-08-13 |
Not clear |
Giovanna Maraula, Daniele Lana, Elisabetta Coppi, Francesca Gentile, Tommaso Mello, Alessia Melani, Andrea Galli, Maria Grazia Giovannini, Felicita Pedata, Anna Maria Puglies. The selective antagonism of P2X7 and P2Y1 receptors prevents synaptic failure and affects cell proliferation induced by oxygen and glucose deprivation in rat dentate gyrus. PloS one. vol 9. issue 12. 2015-12-21. PMID:25526634. |
the aim of this research was to determine the synaptic and proliferative response of the dg to severe oxygen and glucose deprivation (ogd) in acute rat hippocampal slices and to investigate the contribution of p2x7 and p2y1 receptor antagonism to recovery of synaptic activity after ogd. |
2015-12-21 |
2023-08-13 |
rat |
Giovanna Maraula, Daniele Lana, Elisabetta Coppi, Francesca Gentile, Tommaso Mello, Alessia Melani, Andrea Galli, Maria Grazia Giovannini, Felicita Pedata, Anna Maria Puglies. The selective antagonism of P2X7 and P2Y1 receptors prevents synaptic failure and affects cell proliferation induced by oxygen and glucose deprivation in rat dentate gyrus. PloS one. vol 9. issue 12. 2015-12-21. PMID:25526634. |
extracellular field excitatory post-synaptic potentials (fepsps) in granule cells of the dg were recorded from rat hippocampal slices. |
2015-12-21 |
2023-08-13 |
rat |
Patrícia Patrício, António Mateus-Pinheiro, Martin Irmler, Nuno D Alves, Ana R Machado-Santos, Mónica Morais, Joana S Correia, Michal Korostynski, Marcin Piechota, Rainer Stoffel, Johannes Beckers, João M Bessa, Osborne F X Almeida, Nuno Sousa, Luísa Pint. Differential and converging molecular mechanisms of antidepressants' action in the hippocampal dentate gyrus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 2. 2015-12-18. PMID:25035085. |
neuroplastic changes in brain regions such as the hippocampal dentate gyrus (dg) accompany depression and its amelioration with ads. |
2015-12-18 |
2023-08-13 |
rat |
Patrícia Patrício, António Mateus-Pinheiro, Martin Irmler, Nuno D Alves, Ana R Machado-Santos, Mónica Morais, Joana S Correia, Michal Korostynski, Marcin Piechota, Rainer Stoffel, Johannes Beckers, João M Bessa, Osborne F X Almeida, Nuno Sousa, Luísa Pint. Differential and converging molecular mechanisms of antidepressants' action in the hippocampal dentate gyrus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 2. 2015-12-18. PMID:25035085. |
in this study, the unpredictable chronic mild stress (ucms) rat model of depression was used to determine the molecular mediators of chronic stress and the targets of four ads with different pharmacological profiles (fluoxetine, imipramine, tianeptine, and agomelatine) in the hippocampal dg. |
2015-12-18 |
2023-08-13 |
rat |
N Osumi, N Guo, M Matsumata, K Yoshizak. Neurogenesis and sensorimotor gating: bridging a microphenotype and an endophenotype. Current molecular medicine. vol 15. issue 2. 2015-12-18. PMID:25732150. |
we noted impairments in the maturation of newborn neurons in the hippocampal dentate gyrus (dg) and gabaergic neurons in the hippocampus, which could be considered as microphenotypes associated with ppi defects. |
2015-12-18 |
2023-08-13 |
mouse |