| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hong Liu, Xinhong Xue, Huijian Shi, Lifeng Qi, Dianrong Gon. Osthole Upregulates BDNF to Enhance Adult Hippocampal Neurogenesis in APP/PS1 Transgenic Mice. Biological & pharmaceutical bulletin. vol 38. issue 10. 2016-07-25. PMID:26424009. |
once daily) treatment dramatically ameliorated the cognitive impairments by morris water maze test and passive avoidance test, and augmented neurogenesis in the dg of hippocampus in app/ps1 mice. |
2016-07-25 |
2023-08-13 |
mouse |
| Abdeslam Mouihat. Prenatal Activation of Toll-Like Receptor-4 Dampens Adult Hippocampal Neurogenesis in An IL-6 Dependent Manner. Frontiers in cellular neuroscience. vol 10. 2016-07-22. PMID:27445700. |
the newly born neurons were monitored in the subventricular zone (svz) and the dentate gyrus (dg) of the hippocampus of adult male offspring by monitoring doublecortin and t-box brain protein-2 expression: two well-established markers of newly born neurons. |
2016-07-22 |
2023-08-13 |
rat |
| C P Hutton, N Déry, E Rosa, J A Lemon, C D Rollo, D R Boreham, M Fahnestock, D deCatanzaro, J M Wojtowicz, S Becke. Synergistic effects of diet and exercise on hippocampal function in chronically stressed mice. Neuroscience. vol 308. 2016-07-19. PMID:26358368. |
the combination of dietary supplementation and exercise had multiple beneficial effects, as reflected in the number of doublecortin (dcx)-positive immature neurons in the dentate gyrus (dg), the sectional area of the dg and hippocampal ca1, as well as increased hippocampal bdnf messenger ribonucleic acid (mrna) and serum vascular endothelial growth factor (vegf) levels. |
2016-07-19 |
2023-08-13 |
mouse |
| Adva Sharvit, Menahem Segal, Orli Kehat, Oliver Stork, Gal Richter-Levi. Differential modulation of synaptic plasticity and local circuit activity in the dentate gyrus and CA1 regions of the rat hippocampus by corticosterone. Stress (Amsterdam, Netherlands). vol 18. issue 3. 2016-07-13. PMID:25815975. |
we have now examined the effects of corticosterone (cort) on extrinsic afferent and local circuit plasticity of the perforant path on the dentate gyrus (dg) and the ventral hippocampal commissure on ca1. |
2016-07-13 |
2023-08-13 |
rat |
| Mari Kojima, Hiroaki Takehara, Takanori Akagi, Hirofumi Shiono, Takanori Ichik. Flexible Sheet-Type Sensor for Noninvasive Measurement of Cellular Oxygen Metabolism on a Culture Dish. PloS one. vol 10. issue 12. 2016-07-06. PMID:26624889. |
furthermore, to demonstrate the utility of the developed sensing system, we demonstrated the mapping of the oxygen consumption rate of rat brain slices and succeeded in visualizing a clear difference among the layer structures of the hippocampus, i.e., the cornu ammonis (ca1 and ca3) and dentate gyrus (dg). |
2016-07-06 |
2023-08-13 |
human |
| Michael G Ruscio, S Bradley King, Harold L Hau. Social isolation increases cell proliferation in male and cell survival in female California mice (Peromyscus californicus). Physiology & behavior. vol 151. 2016-06-28. PMID:26342752. |
after 4 days, isolated males had greater cellular proliferation in the dentate gyrus of the hippocampus (dg) than pair housed males. |
2016-06-28 |
2023-08-13 |
mouse |
| Jens Stepan, Florian Hladky, Andrés Uribe, Florian Holsboer, Mathias V Schmidt, Matthias Ede. High-Speed imaging reveals opposing effects of chronic stress and antidepressants on neuronal activity propagation through the hippocampal trisynaptic circuit. Frontiers in neural circuits. vol 9. 2016-06-21. PMID:26594153. |
here, enabled by a recently developed voltage-sensitive dye imaging (vsdi) assay in mouse brain slices, we examined the impact of chronic stress and concentration-dependent effects of eight clinically used ads (belonging to different chemical/functional classes) on evoked neuronal activity propagations through the hippocampal trisynaptic circuitry (htc: perforant path → dentate gyrus (dg) → area ca3 → area ca1). |
2016-06-21 |
2023-08-13 |
mouse |
| Sarah M Guadiana, Alexander K Parker, Gileno F Filho, Ashton Sequeira, Susan Semple-Rowland, Gerry Shaw, Ronald J Mandel, Thomas C Foster, Ashok Kumar, Matthew R Sarkisia. Type 3 Adenylyl Cyclase and Somatostatin Receptor 3 Expression Persists in Aged Rat Neocortical and Hippocampal Neuronal Cilia. Frontiers in aging neuroscience. vol 8. 2016-06-15. PMID:27303293. |
the lengths of aciii positive cilia in neocortex were similar between young and aged for both strains, whereas in f344 × bn hippocampus, the cilia lengths increased with age in ca1 and ca3, but not in dentate gyrus (dg). |
2016-06-15 |
2023-08-13 |
rat |
| Liang Ye, Zhengping Hu, Hui Wang, Haibo Zhu, Zhaoju Dong, Wanglin Jiang, Huijuan Zhao, Ning Li, Wei Mi, Wenyan Wang, Xihou H. Tris-(2,3-Dibromopropyl) Isocyanurate, a New Emerging Pollutant, Impairs Cognition and Provokes Depression-Like Behaviors in Adult Rats. PloS one. vol 10. issue 10. 2016-06-08. PMID:26458255. |
tdbp-tazto resulted in cognitive impairment and depression-like behaviors, which may be related with tdbp-tazto-induced hypothalamic-pituitary-adrenal axis hyperactivation, upregulation of inflammatory and oxidative stress markers, overexpression of pro-apoptotic proteins, downexpression of neurogenesis-related proteins in hippocampus, and hippocampal neurons damage in dg, ca1 and ca3 areas. |
2016-06-08 |
2023-08-13 |
human |
| Kuan Zhang, Yanzhao Zhou, Tong Zhao, Liying Wu, Xin Huang, Kuiwu Wu, Lun Xu, Dahu Li, Shuhong Liu, Yongqi Zhao, Ming Fan, Lingling Zh. Reduced Cerebral Oxygen Content in the DG and SVZ In Situ Promotes Neurogenesis in the Adult Rat Brain In Vivo. PloS one. vol 10. issue 10. 2016-06-07. PMID:26466323. |
neurogenesis in the adult brain occurs mainly within two neurogenic structures, the dentate gyrus (dg) of the hippocampus and the sub-ventricular zone (svz) of the forebrain. |
2016-06-07 |
2023-08-13 |
rat |
| Bao-Fei Sun, Qing-Qing Wang, Zi-Jiang Yu, Yan Yu, Chao-Lun Xiao, Chao-Sheng Kang, Guo Ge, Yan Linghu, Jun-De Zhu, Yu-Mei Li, Qiang-Ming Li, Shi-Peng Luo, Dang Yang, Lin Li, Wen-Yan Zhang, Guang Tia. Exercise Prevents Memory Impairment Induced by Arsenic Exposure in Mice: Implication of Hippocampal BDNF and CREB. PloS one. vol 10. issue 9. 2016-06-06. PMID:26368803. |
the expression of brain-derived neurotrophic factor (bdnf) and phosphorylated camp-response element binding protein (pcreb) in the ca1 and dentate gyrus areas (dg) of the dorsal hippocampus were decreased by 3 mg/ kg and 10 mg/ kg, but not by 1 mg/ kg, of arsenic exposure. |
2016-06-06 |
2023-08-13 |
mouse |
| Astha Malik, Roman V Kondratov, Roudabeh J Jamasbi, Michael E Geus. Circadian Clock Genes Are Essential for Normal Adult Neurogenesis, Differentiation, and Fate Determination. PloS one. vol 10. issue 10. 2016-06-02. PMID:26439128. |
it is best understood in the dentate gyrus (dg) of the hippocampus and the subventricular zone (svz). |
2016-06-02 |
2023-08-13 |
mouse |
| Guillaume Martel, Shusaku Uchida, Charles Hevi, Itzamarie Chévere-Torres, Ileana Fuentes, Young Jin Park, Hannah Hafeez, Hirotaka Yamagata, Yoshifumi Watanabe, Gleb P Shumyatsk. Genetic Demonstration of a Role for Stathmin in Adult Hippocampal Neurogenesis, Spinogenesis, and NMDA Receptor-Dependent Memory. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 4. 2016-06-01. PMID:26818507. |
neurogenesis and memory formation are essential features of the dentate gyrus (dg) area of the hippocampus, but to what extent the mechanisms responsible for both processes overlap remains poorly understood. |
2016-06-01 |
2023-08-13 |
mouse |
| Carmen Viva. Adult Hippocampal Neurogenesis, Aging and Neurodegenerative Diseases: Possible Strategies to Prevent Cognitive Impairment. Current topics in medicinal chemistry. vol 15. issue 21. 2016-05-31. PMID:26059358. |
however, this neurogenic capacity is limited to two brain areas, the dentate gyrus (dg of the hippocampus and the subventricular zone (svz of the lateral ventricle. |
2016-05-31 |
2023-08-13 |
Not clear |
| Angélica Pupin Schiavon, Jéssica Mendes Bonato, Humberto Milani, Francisco Silveira Guimarães, Rúbia Maria Weffort de Oliveir. Influence of single and repeated cannabidiol administration on emotional behavior and markers of cell proliferation and neurogenesis in non-stressed mice. Progress in neuro-psychopharmacology & biological psychiatry. vol 64. 2016-05-31. PMID:26187374. |
despite its antidepressant-like effects in the tst, repeated cbd administration at a higher dose (30 mg/kg) decreased cell proliferation and neurogenesis in the hippocampal dg and svz. |
2016-05-31 |
2023-08-13 |
mouse |
| Davide Guerrieri, Henriette van Praa. Exercise-mimetic AICAR transiently benefits brain function. Oncotarget. vol 6. issue 21. 2016-05-20. PMID:26286955. |
at the time-points where we observed equivalent running- and aicar-induced muscle pampk levels (7 and 14 days), cell proliferation, synaptic plasticity and gene expression, as well as markers of oxidative stress and inflammation in the dentate gyrus (dg) of the hippocampus and lateral entorhinal cortex (lec) were evaluated. |
2016-05-20 |
2023-08-13 |
mouse |
| Caine C Smith, Diane Guévremont, Joanna M Williams, Ruth M A Nappe. Apoptotic cell death and temporal expression of apoptotic proteins Bcl-2 and Bax in the hippocampus, following binge ethanol in the neonatal rat model. Alcoholism, clinical and experimental research. vol 39. issue 1. 2016-05-19. PMID:25623404. |
this study investigates acute apoptotic cell death in hippocampal regions ca1, ca3, and dentate gyrus (dg) following a binge etoh exposure on postnatal day (pn) 6, pn8, or pn6 + 8 and the alteration in pro- and anti-apoptotic proteins following a single etoh binge on pn6. |
2016-05-19 |
2023-08-13 |
rat |
| Dayu Sun, Junhua Chen, Xiaohang Bao, Yulong Cai, Jinghui Zhao, Jing Huang, Wei Huang, Xiaotang Fan, Haiwei X. Protection of Radial Glial-Like Cells in the Hippocampus of APP/PS1 Mice: a Novel Mechanism of Memantine in the Treatment of Alzheimer's Disease. Molecular neurobiology. vol 52. issue 1. 2016-05-17. PMID:25195698. |
the failure of adult neurogenesis in the hippocampal dentate gyrus (dg) is closely correlated with memory decline in alzheimer's disease (ad). |
2016-05-17 |
2023-08-13 |
mouse |
| Dayu Sun, Junhua Chen, Xiaohang Bao, Yulong Cai, Jinghui Zhao, Jing Huang, Wei Huang, Xiaotang Fan, Haiwei X. Protection of Radial Glial-Like Cells in the Hippocampus of APP/PS1 Mice: a Novel Mechanism of Memantine in the Treatment of Alzheimer's Disease. Molecular neurobiology. vol 52. issue 1. 2016-05-17. PMID:25195698. |
radial glial-like cells (rgls) localized to the adult dg generate intermediate progenitor cells and immature neurons and thus contribute to adult hippocampus neurogenesis. |
2016-05-17 |
2023-08-13 |
mouse |
| Dayu Sun, Junhua Chen, Xiaohang Bao, Yulong Cai, Jinghui Zhao, Jing Huang, Wei Huang, Xiaotang Fan, Haiwei X. Protection of Radial Glial-Like Cells in the Hippocampus of APP/PS1 Mice: a Novel Mechanism of Memantine in the Treatment of Alzheimer's Disease. Molecular neurobiology. vol 52. issue 1. 2016-05-17. PMID:25195698. |
mem could enhance hippocampal neurogenesis and increase the number of rgls in the dg subgranular zone (dg-sgz) of app/ps1 mice of both ages. |
2016-05-17 |
2023-08-13 |
mouse |